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The map label for this gene is cinA [C]

Identifier: 99082307

GI number: 99082307

Start: 2607783

End: 2608505

Strand: Reverse

Name: cinA [C]

Synonym: TM1040_2467

Alternate gene names: 99082307

Gene position: 2608505-2607783 (Counterclockwise)

Preceding gene: 99082310

Following gene: 99082306

Centisome position: 81.49

GC content: 60.44

Gene sequence:

>723_bases
ATGCCCAACCCCACCGCCGCGATGCTTGTGATCGGGGATGAAATACTGTCTGGGCGCACACGCGATGCAAATATGTACTA
TCTCGCTGGCGAATTGGCCAAACACGGCGTTGACCTAAAGGAAGTCCGCGTGGTGAGCGACGACGCGGCTGCAATCGTTA
CTGCCGTCAAAGCGCTGTCAGGGGCCTATGACCATGTGTTTACCTCTGGCGGGATTGGCCCCACGCATGATGACATCACC
GCAGATTGCATTGCCGAGGCTTTTGGGGCCGCGATTGATGTGCGCGCCGATGCCCGCGCGATCCTCGAAGAGCATTACGC
CAAGACAGGCGCAGAGCTGAACGAGGCGCGTTTGCGCATGGCCCGCATACCCGATGGGGCCGCGTTGATTGACAATCCCG
TATCGCGCGCGCCCGGTTTTACCTTGGGCAATGTTCACGTTATGGCGGGGGTGCCGGCGGTGTTTCAGGCAATGGTGGAA
ACCGTTCTGGCCACTCTGGCTGGGGGTAAGCCCCTCCTGAGTCAAACCTTGCGTGTGGAGCGCGGGGAGGGCGAGATTGC
CGCGACCTTGTCGGCGCTGGCAGAAAAATTTGGCGACCTCTCGATTGGCTGCTACCCGTTTCAGGTCAACGGTGCTTTTG
GCGCCAATGTCGTTGTGCGCGGAACAGAAGGCGCGCGTGTGGACGCCGCAATCACAGAGCTTGCACGGGATCTCGGCGTG
TGA

Upstream 100 bases:

>100_bases
TCCGCGCGCTGTCAAAGCGTCAGAGGCCCAATCCGCTTGCACCGACTGTCGGGGCGGCTATCCTCTTGGTGGACGCCGCA
AAACTCACAGGAGACGAGCC

Downstream 100 bases:

>100_bases
CAGAGGCGCAGACCGATCCCAAATATTATGATGTGGTAGAGGCCACATGGCCTTGTCTGCGATGCGAAAAGCTAGGCGAT
ATCACTTTGCGCGTCGGTGC

Product: molybdopterin binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MPNPTAAMLVIGDEILSGRTRDANMYYLAGELAKHGVDLKEVRVVSDDAAAIVTAVKALSGAYDHVFTSGGIGPTHDDIT
ADCIAEAFGAAIDVRADARAILEEHYAKTGAELNEARLRMARIPDGAALIDNPVSRAPGFTLGNVHVMAGVPAVFQAMVE
TVLATLAGGKPLLSQTLRVERGEGEIAATLSALAEKFGDLSIGCYPFQVNGAFGANVVVRGTEGARVDAAITELARDLGV

Sequences:

>Translated_240_residues
MPNPTAAMLVIGDEILSGRTRDANMYYLAGELAKHGVDLKEVRVVSDDAAAIVTAVKALSGAYDHVFTSGGIGPTHDDIT
ADCIAEAFGAAIDVRADARAILEEHYAKTGAELNEARLRMARIPDGAALIDNPVSRAPGFTLGNVHVMAGVPAVFQAMVE
TVLATLAGGKPLLSQTLRVERGEGEIAATLSALAEKFGDLSIGCYPFQVNGAFGANVVVRGTEGARVDAAITELARDLGV
>Mature_239_residues
PNPTAAMLVIGDEILSGRTRDANMYYLAGELAKHGVDLKEVRVVSDDAAAIVTAVKALSGAYDHVFTSGGIGPTHDDITA
DCIAEAFGAAIDVRADARAILEEHYAKTGAELNEARLRMARIPDGAALIDNPVSRAPGFTLGNVHVMAGVPAVFQAMVET
VLATLAGGKPLLSQTLRVERGEGEIAATLSALAEKFGDLSIGCYPFQVNGAFGANVVVRGTEGARVDAAITELARDLGV

Specific function: Unknown

COG id: COG1058

COG function: function code R; Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CinA family [H]

Homologues:

Organism=Homo sapiens, GI41872403, Length=208, Percent_Identity=33.1730769230769, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI296434309, Length=208, Percent_Identity=33.1730769230769, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI41872389, Length=208, Percent_Identity=33.1730769230769, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI296434312, Length=196, Percent_Identity=31.6326530612245, Blast_Score=88, Evalue=8e-18,
Organism=Escherichia coli, GI1788583, Length=157, Percent_Identity=32.484076433121, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71993974, Length=259, Percent_Identity=33.976833976834, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71993966, Length=259, Percent_Identity=33.976833976834, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323832, Length=225, Percent_Identity=28.8888888888889, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR001453
- InterPro:   IPR023055 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 24915; Mature: 24783

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNPTAAMLVIGDEILSGRTRDANMYYLAGELAKHGVDLKEVRVVSDDAAAIVTAVKALS
CCCCCEEEEEECHHHHCCCCCCCCEEEEEHHHHHCCCCHHHEEEECCCHHHHHHHHHHHH
GAYDHVFTSGGIGPTHDDITADCIAEAFGAAIDVRADARAILEEHYAKTGAELNEARLRM
CHHHHHEECCCCCCCCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCCCHHHHHHHHH
ARIPDGAALIDNPVSRAPGFTLGNVHVMAGVPAVFQAMVETVLATLAGGKPLLSQTLRVE
HCCCCCCHHHCCCHHHCCCCEECCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
RGEGEIAATLSALAEKFGDLSIGCYPFQVNGAFGANVVVRGTEGARVDAAITELARDLGV
CCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PNPTAAMLVIGDEILSGRTRDANMYYLAGELAKHGVDLKEVRVVSDDAAAIVTAVKALS
CCCCEEEEEECHHHHCCCCCCCCEEEEEHHHHHCCCCHHHEEEECCCHHHHHHHHHHHH
GAYDHVFTSGGIGPTHDDITADCIAEAFGAAIDVRADARAILEEHYAKTGAELNEARLRM
CHHHHHEECCCCCCCCCCHHHHHHHHHHCCEEECCHHHHHHHHHHHHHCCCHHHHHHHHH
ARIPDGAALIDNPVSRAPGFTLGNVHVMAGVPAVFQAMVETVLATLAGGKPLLSQTLRVE
HCCCCCCHHHCCCHHHCCCCEECCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHC
RGEGEIAATLSALAEKFGDLSIGCYPFQVNGAFGANVVVRGTEGARVDAAITELARDLGV
CCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]