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The map label for this gene is hprK [H]

Identifier: 99082279

GI number: 99082279

Start: 2579157

End: 2579645

Strand: Reverse

Name: hprK [H]

Synonym: TM1040_2439

Alternate gene names: 99082279

Gene position: 2579645-2579157 (Counterclockwise)

Preceding gene: 99082280

Following gene: 99082278

Centisome position: 80.59

GC content: 60.12

Gene sequence:

>489_bases
TTGTGGTCGGTCTGCCGGTCTGAGCGGGTGAATACCGCGTCGCCCGACCTCGACGTCATTTTATTGCACGCCAGTTGCGT
CGCGCTCGATGAGCGCGGCGTTTTGCTCTGTGGCCCCTCCGGGAGCGGTAAATCGGCGCTTGCTTTGGAACTGATGGCAC
GTGGTGCGATCCTAGTGGCCGACGATAAGACCGAGGTCTTTAGGGACGGCGCGGTTTTGCGCGCGCGTGCGCCCGAAACG
ATCTCAGGCCTCATTGAGGCGCGCGGTGTGGGGCTTCTCCGCGCTGAGACGCTGGCGCAGGTGCGACTTTGCGTCGTGGT
CGACTTGGGTCAACTTGAAACCGACCGTCTGCCGCGCCACCTAAAGGAAGAGGTGTTGGGAATTTCATTGCCCAAGGTGA
ACCGAATCGACGGCGCGCATTTTCCGGCAGCTTTGATCCAATATGTGAAAGGTGGAGCACTTGACCCCGAAACAGAGCCC
AAACTCTGA

Upstream 100 bases:

>100_bases
ATTTCCAAGCAGATTGTTGAGGCGCATGGCGGCGTGATCTGGGCGGAGAACATTCGCCCCACCGAGGCGGATCTGACCTC
CGAGCCGCTCGGAGCTCGTT

Downstream 100 bases:

>100_bases
GACTGGTGCGGTAACCGAGCCGCCACTGGTGTTGGTCACCGGTCCCTCGGGGGCGGGGCGCACCACTGCAATCAACGTAC
TCGAAGACTTGGATTTTGAG

Product: Hpr(Ser) kinase/phosphatase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MWSVCRSERVNTASPDLDVILLHASCVALDERGVLLCGPSGSGKSALALELMARGAILVADDKTEVFRDGAVLRARAPET
ISGLIEARGVGLLRAETLAQVRLCVVVDLGQLETDRLPRHLKEEVLGISLPKVNRIDGAHFPAALIQYVKGGALDPETEP
KL

Sequences:

>Translated_162_residues
MWSVCRSERVNTASPDLDVILLHASCVALDERGVLLCGPSGSGKSALALELMARGAILVADDKTEVFRDGAVLRARAPET
ISGLIEARGVGLLRAETLAQVRLCVVVDLGQLETDRLPRHLKEEVLGISLPKVNRIDGAHFPAALIQYVKGGALDPETEP
KL
>Mature_162_residues
MWSVCRSERVNTASPDLDVILLHASCVALDERGVLLCGPSGSGKSALALELMARGAILVADDKTEVFRDGAVLRARAPET
ISGLIEARGVGLLRAETLAQVRLCVVVDLGQLETDRLPRHLKEEVLGISLPKVNRIDGAHFPAALIQYVKGGALDPETEP
KL

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 17313; Mature: 17313

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSVCRSERVNTASPDLDVILLHASCVALDERGVLLCGPSGSGKSALALELMARGAILVA
CCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHCCEEEEE
DDKTEVFRDGAVLRARAPETISGLIEARGVGLLRAETLAQVRLCVVVDLGQLETDRLPRH
CCCHHHHHCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHEEEEEEEECCCCCHHHHHHH
LKEEVLGISLPKVNRIDGAHFPAALIQYVKGGALDPETEPKL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MWSVCRSERVNTASPDLDVILLHASCVALDERGVLLCGPSGSGKSALALELMARGAILVA
CCCCCCCCCCCCCCCCCEEEEEEEEEEEECCCCEEEECCCCCCCHHHHHHHHHCCEEEEE
DDKTEVFRDGAVLRARAPETISGLIEARGVGLLRAETLAQVRLCVVVDLGQLETDRLPRH
CCCHHHHHCCCEEEECCCHHHHHHHHHCCCCHHHHHHHHHEEEEEEEECCCCCHHHHHHH
LKEEVLGISLPKVNRIDGAHFPAALIQYVKGGALDPETEPKL
HHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA