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The map label for this gene is chvG [H]

Identifier: 99082280

GI number: 99082280

Start: 2579623

End: 2581356

Strand: Reverse

Name: chvG [H]

Synonym: TM1040_2440

Alternate gene names: 99082280

Gene position: 2581356-2579623 (Counterclockwise)

Preceding gene: 99082281

Following gene: 99082279

Centisome position: 80.64

GC content: 59.05

Gene sequence:

>1734_bases
ATGCGCGATAGTAGCATGACCGATACACACCGGCAGACGGGCCGGGATTCACGCCGGGACGGGGATCTGGTGCTGGGTGA
CGATTGGGTCGCACCAGAGCAGACGGTCGGGCGCGAAATGCGGGCCAAACGGGCGCGGCGTGGCTGGTTTTCGCTGCGCG
GTTCTCCGCTGGCGCGTAAAATCATCACCTTCAACCTGATTGCACTGATCATCCTTGTGTCGGGGATCCTCTATTTGAAC
TCCGCGCGGCAGAGCCTTGTATACCAGCGGCTTGGCACATTGGTATCCGAGGCGATGCTGGCTACGGATGTACTTGAGGT
GCAGCTTTTTGAGGGGGGCGAGGCTGGTGTCACACCCAGCGCGGAGGATATTTCGCGCACGCTCGATAATATTTCGTTGC
GTGGCGGCGTTGAAATTTTTGTGTTTGATACGTCGCTGACCCTGTTGGACCAGCAAAAAGGCGTCATGCGTGCGGATGCG
CTCAATCGGCTCAACGACAATGAGGGCGGGCGCACCCTGATCACTGACACGCTCAAGGCGATCTGGTCTGCGGTGGGCGG
CGAAAGCGCGCCGGAAAACGTCGTGGCCGAGATCGACCTGACCGAACCCCAGCTTTTGTCTCTCATTCAGCGTGCGCTCA
GCGATGGAACACAGGTGGGGGCGGTGCCCGACAGTGCAGGCGGAACCGTTTACGCCGCGACCAATCCGATTTTGCAGCAG
GGCCAGGCAACGGGCGTTCTGTTGATGACTTCGGCAACTGGCGAAATCGACCGTCTCGTCCGCATCGAACGTGAGCGGGT
ATTGCAGATGTTCATCGTCGCCCTCCTGGTCTCTATCGGGTTGAGCCTCGTGCTGGCTTCCACGATCGCCAACCCCCTTG
CCGATCTGGCCGAGGCGGCAGAGCTCGGCAAGGACCGCGACAACGACAAGGTCAAACCGGGACGCATTCGCATTCCGGAC
CTCTCGGCGCGCCCGGATGAGATCGGCCGCCTGAGCCGCGCCCTGCGTGGAATGGTCAAAGCGCTCTATAATCGTATCGA
TAGTAACGAACAATTTGCAGCTGATGTGGCACATGAGATCAAGAATCCTCTGGCCAGTTTGCAGTCTGCGGTCGGCACGC
TCCGGATGGTTCACCGAGAAGACCAACGGGAGAAGCTGATGGAAGTGATTGAACATGATGTGCGCCGTCTCGATCGGTTG
GTGAGCGACATTTCCAATGCGTCCCGGTTGGATGCAGAGCTGGTGAAAGAGGACGAAGAAGACTTTGACCTTCTCAAGAT
GCTCGGCAATCTCAACCAGTATTTGGGCGAAGACGCCCGCGGCAAGGGAATCGATTACATCACCGAGCTGCCGAATGAGC
CGATCTTGATCCGGGGTCTCGAGGCCCGTTTGGCGCAGGTTTTTGTCAATCTGATCACCAACGCAATTTCGTTCTGCGAA
GAGGGCGATGCGATCCGTGTCTGGGCGCGGCGGCGGGACAATCGTGTCCTGATCGTGGTCGAAGACACCGGCCCCGGCAT
TCCAGAGCAGGCATTGTCCAAGGTCTTCAAGCGCTTCTATTCTCAGCGCCCCGAAGAGCATTTTGGCAACAATTCCGGCC
TTGGGCTTGCGATTTCCAAGCAGATTGTTGAGGCGCATGGCGGCGTGATCTGGGCGGAGAACATTCGCCCCACCGAGGCG
GATCTGACCTCCGAGCCGCTCGGAGCTCGTTTTGTGGTCGGTCTGCCGGTCTGA

Upstream 100 bases:

>100_bases
TGCGGATTTCGCAGCGATCGAGACCCTCTATGGGATCGGCTACCGCTACAATGAAGAATAAGACCCCGACTTTCGGGGTC
TTTGGCGGAGACATGCGTGC

Downstream 100 bases:

>100_bases
GCGGGTGAATACCGCGTCGCCCGACCTCGACGTCATTTTATTGCACGCCAGTTGCGTCGCGCTCGATGAGCGCGGCGTTT
TGCTCTGTGGCCCCTCCGGG

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 577; Mature: 577

Protein sequence:

>577_residues
MRDSSMTDTHRQTGRDSRRDGDLVLGDDWVAPEQTVGREMRAKRARRGWFSLRGSPLARKIITFNLIALIILVSGILYLN
SARQSLVYQRLGTLVSEAMLATDVLEVQLFEGGEAGVTPSAEDISRTLDNISLRGGVEIFVFDTSLTLLDQQKGVMRADA
LNRLNDNEGGRTLITDTLKAIWSAVGGESAPENVVAEIDLTEPQLLSLIQRALSDGTQVGAVPDSAGGTVYAATNPILQQ
GQATGVLLMTSATGEIDRLVRIERERVLQMFIVALLVSIGLSLVLASTIANPLADLAEAAELGKDRDNDKVKPGRIRIPD
LSARPDEIGRLSRALRGMVKALYNRIDSNEQFAADVAHEIKNPLASLQSAVGTLRMVHREDQREKLMEVIEHDVRRLDRL
VSDISNASRLDAELVKEDEEDFDLLKMLGNLNQYLGEDARGKGIDYITELPNEPILIRGLEARLAQVFVNLITNAISFCE
EGDAIRVWARRRDNRVLIVVEDTGPGIPEQALSKVFKRFYSQRPEEHFGNNSGLGLAISKQIVEAHGGVIWAENIRPTEA
DLTSEPLGARFVVGLPV

Sequences:

>Translated_577_residues
MRDSSMTDTHRQTGRDSRRDGDLVLGDDWVAPEQTVGREMRAKRARRGWFSLRGSPLARKIITFNLIALIILVSGILYLN
SARQSLVYQRLGTLVSEAMLATDVLEVQLFEGGEAGVTPSAEDISRTLDNISLRGGVEIFVFDTSLTLLDQQKGVMRADA
LNRLNDNEGGRTLITDTLKAIWSAVGGESAPENVVAEIDLTEPQLLSLIQRALSDGTQVGAVPDSAGGTVYAATNPILQQ
GQATGVLLMTSATGEIDRLVRIERERVLQMFIVALLVSIGLSLVLASTIANPLADLAEAAELGKDRDNDKVKPGRIRIPD
LSARPDEIGRLSRALRGMVKALYNRIDSNEQFAADVAHEIKNPLASLQSAVGTLRMVHREDQREKLMEVIEHDVRRLDRL
VSDISNASRLDAELVKEDEEDFDLLKMLGNLNQYLGEDARGKGIDYITELPNEPILIRGLEARLAQVFVNLITNAISFCE
EGDAIRVWARRRDNRVLIVVEDTGPGIPEQALSKVFKRFYSQRPEEHFGNNSGLGLAISKQIVEAHGGVIWAENIRPTEA
DLTSEPLGARFVVGLPV
>Mature_577_residues
MRDSSMTDTHRQTGRDSRRDGDLVLGDDWVAPEQTVGREMRAKRARRGWFSLRGSPLARKIITFNLIALIILVSGILYLN
SARQSLVYQRLGTLVSEAMLATDVLEVQLFEGGEAGVTPSAEDISRTLDNISLRGGVEIFVFDTSLTLLDQQKGVMRADA
LNRLNDNEGGRTLITDTLKAIWSAVGGESAPENVVAEIDLTEPQLLSLIQRALSDGTQVGAVPDSAGGTVYAATNPILQQ
GQATGVLLMTSATGEIDRLVRIERERVLQMFIVALLVSIGLSLVLASTIANPLADLAEAAELGKDRDNDKVKPGRIRIPD
LSARPDEIGRLSRALRGMVKALYNRIDSNEQFAADVAHEIKNPLASLQSAVGTLRMVHREDQREKLMEVIEHDVRRLDRL
VSDISNASRLDAELVKEDEEDFDLLKMLGNLNQYLGEDARGKGIDYITELPNEPILIRGLEARLAQVFVNLITNAISFCE
EGDAIRVWARRRDNRVLIVVEDTGPGIPEQALSKVFKRFYSQRPEEHFGNNSGLGLAISKQIVEAHGGVIWAENIRPTEA
DLTSEPLGARFVVGLPV

Specific function: Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.5652173913043, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786783, Length=266, Percent_Identity=26.6917293233083, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1790346, Length=315, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=26.5873015873016, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1790861, Length=335, Percent_Identity=26.5671641791045, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=29.8319327731092, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789403, Length=278, Percent_Identity=27.6978417266187, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788549, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=207, Percent_Identity=28.5024154589372, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=283, Percent_Identity=26.5017667844523, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=200, Percent_Identity=29.5, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1789149, Length=218, Percent_Identity=29.8165137614679, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081816, Length=337, Percent_Identity=27.0029673590504, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790551, Length=296, Percent_Identity=28.0405405405405, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=339, Percent_Identity=25.3687315634218, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1788713, Length=239, Percent_Identity=25.5230125523013, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63389; Mature: 63389

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDSSMTDTHRQTGRDSRRDGDLVLGDDWVAPEQTVGREMRAKRARRGWFSLRGSPLARK
CCCCCCCHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHH
IITFNLIALIILVSGILYLNSARQSLVYQRLGTLVSEAMLATDVLEVQLFEGGEAGVTPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
AEDISRTLDNISLRGGVEIFVFDTSLTLLDQQKGVMRADALNRLNDNEGGRTLITDTLKA
HHHHHHHHHCCEECCCCEEEEEECCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHH
IWSAVGGESAPENVVAEIDLTEPQLLSLIQRALSDGTQVGAVPDSAGGTVYAATNPILQQ
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCHHHHC
GQATGVLLMTSATGEIDRLVRIERERVLQMFIVALLVSIGLSLVLASTIANPLADLAEAA
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGKDRDNDKVKPGRIRIPDLSARPDEIGRLSRALRGMVKALYNRIDSNEQFAADVAHEI
HHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KNPLASLQSAVGTLRMVHREDQREKLMEVIEHDVRRLDRLVSDISNASRLDAELVKEDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DFDLLKMLGNLNQYLGEDARGKGIDYITELPNEPILIRGLEARLAQVFVNLITNAISFCE
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
EGDAIRVWARRRDNRVLIVVEDTGPGIPEQALSKVFKRFYSQRPEEHFGNNSGLGLAISK
CCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHH
QIVEAHGGVIWAENIRPTEADLTSEPLGARFVVGLPV
HHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MRDSSMTDTHRQTGRDSRRDGDLVLGDDWVAPEQTVGREMRAKRARRGWFSLRGSPLARK
CCCCCCCHHHHHCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCHHHCCCCHHHHH
IITFNLIALIILVSGILYLNSARQSLVYQRLGTLVSEAMLATDVLEVQLFEGGEAGVTPS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCC
AEDISRTLDNISLRGGVEIFVFDTSLTLLDQQKGVMRADALNRLNDNEGGRTLITDTLKA
HHHHHHHHHCCEECCCCEEEEEECCCHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHH
IWSAVGGESAPENVVAEIDLTEPQLLSLIQRALSDGTQVGAVPDSAGGTVYAATNPILQQ
HHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCEECCCCCCCCCEEEEECCHHHHC
GQATGVLLMTSATGEIDRLVRIERERVLQMFIVALLVSIGLSLVLASTIANPLADLAEAA
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELGKDRDNDKVKPGRIRIPDLSARPDEIGRLSRALRGMVKALYNRIDSNEQFAADVAHEI
HHCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
KNPLASLQSAVGTLRMVHREDQREKLMEVIEHDVRRLDRLVSDISNASRLDAELVKEDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
DFDLLKMLGNLNQYLGEDARGKGIDYITELPNEPILIRGLEARLAQVFVNLITNAISFCE
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
EGDAIRVWARRRDNRVLIVVEDTGPGIPEQALSKVFKRFYSQRPEEHFGNNSGLGLAISK
CCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCHHHHH
QIVEAHGGVIWAENIRPTEADLTSEPLGARFVVGLPV
HHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8407839; 11743193; 11743194 [H]