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The map label for this gene is prmA [H]

Identifier: 99082216

GI number: 99082216

Start: 2495256

End: 2496125

Strand: Reverse

Name: prmA [H]

Synonym: TM1040_2376

Alternate gene names: 99082216

Gene position: 2496125-2495256 (Counterclockwise)

Preceding gene: 99082217

Following gene: 99082215

Centisome position: 77.98

GC content: 59.43

Gene sequence:

>870_bases
ATGCCCACATTCACCGCCCTCACCACGCTGTCCGAAAAAGCTCAGGCAGAGGCGCTGGGCGAGGCAATGGAACGTCTGAC
CCCCGAGCCCACGGGCATTGGCGTTTTCGAGGTCGAGGATGGCTCAGGCCTATGGGAAGTGGGCGGCTATTTTACCGAAG
CCCCGGATGAGGCGGGGCTGGCGCTGTTGGCCGCAATGCACGATGCCAAACCCTTTGCCGTGTCCGAATTGCCAGAGACC
GACTGGGTGGCCCATGTACGCCGCGAGCTTGCCCCGGTGGAGGCTGGGCGCTTTTTTGTCTACGGTAGCCATGACGCCGA
CAAGGTTCCCGCAGACAAGATCCCGCTTCTGATCGAGGCGGCCATGGCCTTTGGCACCGGGCATCACGGCACCACGCTTG
GCTGCCTCAAGGCGCTGGATCATCTGCTTTGCGAAGGCTTCGAAGGCAAGAAAGTGGCCGATATTGGATGTGGCACAGCT
GTCCTTGCAATGGCCGCTGCGCGGGTCTGGCCCACGGCGCAGATCCTGGCGAGCGACATCGACGAGGTCGCTGTCGATGT
GGCAGAGGCCAACATGGACGCCAATGGCATGAAGGGCGCGGTCGCATGTCTGGAGGCCGCAGGCTTTGACGCACCAGCGC
TAAAGGCTGCTGCACCGTATGATCTGATCTTCGCAAATATTCTCAAAGGCCCTCTGGTGGCGCTTGCGCCGGACATGGCG
GCTCATTTGCGCGCAGGCGGGTATGCGATTCTCTCCGGGATTTTGAACGAGCAGGCCGATGATGTGATTGCGGTTTATGC
ACAAAACGGCATCAATCTTGTCAAAAGGACTGAAATTGGTGAATGGACCACTTTGATTTTGTCAAAGTAA

Upstream 100 bases:

>100_bases
GGGCGGCGCGGCTCTGCTCACCCCTTGACCAATCACACAAGGCTCGCGTAGGCGCTGATCAACCGCGCGCGACGCGCTCT
ATGTTTCGTTGGAGATCCCC

Downstream 100 bases:

>100_bases
ATCAGAGGTCGGCGGCAATTTAGTCAAATTGCTGGTAATCGCCGTGACTTCGCCGATTTCCTTAAGTAAACTCTAATAAT
CCGCTGGTGGGGGCCAGTTC

Product: 50S ribosomal protein L11P methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MPTFTALTTLSEKAQAEALGEAMERLTPEPTGIGVFEVEDGSGLWEVGGYFTEAPDEAGLALLAAMHDAKPFAVSELPET
DWVAHVRRELAPVEAGRFFVYGSHDADKVPADKIPLLIEAAMAFGTGHHGTTLGCLKALDHLLCEGFEGKKVADIGCGTA
VLAMAAARVWPTAQILASDIDEVAVDVAEANMDANGMKGAVACLEAAGFDAPALKAAAPYDLIFANILKGPLVALAPDMA
AHLRAGGYAILSGILNEQADDVIAVYAQNGINLVKRTEIGEWTTLILSK

Sequences:

>Translated_289_residues
MPTFTALTTLSEKAQAEALGEAMERLTPEPTGIGVFEVEDGSGLWEVGGYFTEAPDEAGLALLAAMHDAKPFAVSELPET
DWVAHVRRELAPVEAGRFFVYGSHDADKVPADKIPLLIEAAMAFGTGHHGTTLGCLKALDHLLCEGFEGKKVADIGCGTA
VLAMAAARVWPTAQILASDIDEVAVDVAEANMDANGMKGAVACLEAAGFDAPALKAAAPYDLIFANILKGPLVALAPDMA
AHLRAGGYAILSGILNEQADDVIAVYAQNGINLVKRTEIGEWTTLILSK
>Mature_288_residues
PTFTALTTLSEKAQAEALGEAMERLTPEPTGIGVFEVEDGSGLWEVGGYFTEAPDEAGLALLAAMHDAKPFAVSELPETD
WVAHVRRELAPVEAGRFFVYGSHDADKVPADKIPLLIEAAMAFGTGHHGTTLGCLKALDHLLCEGFEGKKVADIGCGTAV
LAMAAARVWPTAQILASDIDEVAVDVAEANMDANGMKGAVACLEAAGFDAPALKAAAPYDLIFANILKGPLVALAPDMAA
HLRAGGYAILSGILNEQADDVIAVYAQNGINLVKRTEIGEWTTLILSK

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=164, Percent_Identity=31.7073170731707, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30241; Mature: 30110

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFTALTTLSEKAQAEALGEAMERLTPEPTGIGVFEVEDGSGLWEVGGYFTEAPDEAGL
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEECCCCEECCCCCHHHH
ALLAAMHDAKPFAVSELPETDWVAHVRRELAPVEAGRFFVYGSHDADKVPADKIPLLIEA
HHHHHHHCCCCCCHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
AMAFGTGHHGTTLGCLKALDHLLCEGFEGKKVADIGCGTAVLAMAAARVWPTAQILASDI
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHH
DEVAVDVAEANMDANGMKGAVACLEAAGFDAPALKAAAPYDLIFANILKGPLVALAPDMA
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCCHHHCCCHHH
AHLRAGGYAILSGILNEQADDVIAVYAQNGINLVKRTEIGEWTTLILSK
HHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCEEEEEECC
>Mature Secondary Structure 
PTFTALTTLSEKAQAEALGEAMERLTPEPTGIGVFEVEDGSGLWEVGGYFTEAPDEAGL
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEECCCCEECCCCCHHHH
ALLAAMHDAKPFAVSELPETDWVAHVRRELAPVEAGRFFVYGSHDADKVPADKIPLLIEA
HHHHHHHCCCCCCHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCHHHHHH
AMAFGTGHHGTTLGCLKALDHLLCEGFEGKKVADIGCGTAVLAMAAARVWPTAQILASDI
HHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCHHHHHHHHH
DEVAVDVAEANMDANGMKGAVACLEAAGFDAPALKAAAPYDLIFANILKGPLVALAPDMA
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHCCCHHHCCCHHH
AHLRAGGYAILSGILNEQADDVIAVYAQNGINLVKRTEIGEWTTLILSK
HHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]