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The map label for this gene is tolR [H]

Identifier: 99082207

GI number: 99082207

Start: 2489250

End: 2489738

Strand: Reverse

Name: tolR [H]

Synonym: TM1040_2367

Alternate gene names: 99082207

Gene position: 2489738-2489250 (Counterclockwise)

Preceding gene: 99082208

Following gene: 99082206

Centisome position: 77.78

GC content: 64.62

Gene sequence:

>489_bases
ATGGGAGCCGGTGTTCAGACAAAGGATGCAGGCGGTGGCCGCCGGCGCGGACGGCGTCGGTCGCGCGCGCGCCCGATGGC
AGAGATCAACATCACGCCCTTTGTGGATGTGATGCTGGTGCTTCTGATCATCTTCATGGTTGCAGCCCCGCTGATGACAG
TGGGCGTGCCCGTCGAGTTGCCGAAAACCGCCGCAGGCGCGCTGGCCGGGGATGATGAAGAACCGCTCACCGTGACCATG
ACTGCCGCAGGTGACATCCAGATCCAGACCACGCCGGTTGCGCGCGATCAGCTTGTGGCGCGTCTCCAGGCAATTGCGGC
CGAACGCGACTCGGATCGGGTCTATTTGCGTGCTGATGGGGCGATTGCCTACAGCGATGTCATGCAGGTGATGGGCGCGC
TCAATGCGGGTGGGTTTGCCAATGTGGGGCTTGTGACCGACCAGGGCGGCCCTGCACTCGACGGGCGGTCTGCCGCCCCG
GCAGAGTAA

Upstream 100 bases:

>100_bases
TAACAAACTCTCGGCGGATTCTGATCGCATCATTGGCGGCTATGAGGCCTTTGCTGATGAATTCGCGACCATCTTCTCGC
GCCAGTTGGACAGCTGAGCC

Downstream 100 bases:

>100_bases
CACGGGTGCGGATGTGCAAACCGGCACAAAGATCTCTCTCGCGGGGCATGGCCTCCTGATCACCTGGGCGCTGGCTGGCG
GGTGGCTCAATCCTGAGCCG

Product: biopolymer transport protein ExbD/TolR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MGAGVQTKDAGGGRRRGRRRSRARPMAEINITPFVDVMLVLLIIFMVAAPLMTVGVPVELPKTAAGALAGDDEEPLTVTM
TAAGDIQIQTTPVARDQLVARLQAIAAERDSDRVYLRADGAIAYSDVMQVMGALNAGGFANVGLVTDQGGPALDGRSAAP
AE

Sequences:

>Translated_162_residues
MGAGVQTKDAGGGRRRGRRRSRARPMAEINITPFVDVMLVLLIIFMVAAPLMTVGVPVELPKTAAGALAGDDEEPLTVTM
TAAGDIQIQTTPVARDQLVARLQAIAAERDSDRVYLRADGAIAYSDVMQVMGALNAGGFANVGLVTDQGGPALDGRSAAP
AE
>Mature_161_residues
GAGVQTKDAGGGRRRGRRRSRARPMAEINITPFVDVMLVLLIIFMVAAPLMTVGVPVELPKTAAGALAGDDEEPLTVTMT
AAGDIQIQTTPVARDQLVARLQAIAAERDSDRVYLRADGAIAYSDVMQVMGALNAGGFANVGLVTDQGGPALDGRSAAPA
E

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0848

COG function: function code U; Biopolymer transport protein

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbD/tolR family [H]

Homologues:

Organism=Escherichia coli, GI1789380, Length=127, Percent_Identity=38.5826771653543, Blast_Score=94, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014168
- InterPro:   IPR003400 [H]

Pfam domain/function: PF02472 ExbD [H]

EC number: NA

Molecular weight: Translated: 16816; Mature: 16684

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGVQTKDAGGGRRRGRRRSRARPMAEINITPFVDVMLVLLIIFMVAAPLMTVGVPVEL
CCCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKTAAGALAGDDEEPLTVTMTAAGDIQIQTTPVARDQLVARLQAIAAERDSDRVYLRADG
CCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECC
AIAYSDVMQVMGALNAGGFANVGLVTDQGGPALDGRSAAPAE
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GAGVQTKDAGGGRRRGRRRSRARPMAEINITPFVDVMLVLLIIFMVAAPLMTVGVPVEL
CCCCCCCCCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKTAAGALAGDDEEPLTVTMTAAGDIQIQTTPVARDQLVARLQAIAAERDSDRVYLRADG
CCCCCCCCCCCCCCCEEEEEEECCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEECC
AIAYSDVMQVMGALNAGGFANVGLVTDQGGPALDGRSAAPAE
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8955385; 10984043 [H]