Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 99082145

GI number: 99082145

Start: 2423398

End: 2424741

Strand: Reverse

Name: glmM

Synonym: TM1040_2305

Alternate gene names: 99082145

Gene position: 2424741-2423398 (Counterclockwise)

Preceding gene: 99082146

Following gene: 99082142

Centisome position: 75.75

GC content: 63.32

Gene sequence:

>1344_bases
ATGCGGAAACTCTTTGGAACCGATGGCGTGCGTGGCAAGGCCAATATGCATCCGATGACCGCCGAGATGGCGCTTCGGAT
CGGGGCCGCTGTTGGGCGCTACTTCCGGCGTGAAAACGACACCGTGCACCGGGTGGTGATCGGCAAGGACACCCGCCTCT
CGGGCTATATGTTTGAAAACGCGCTGACGGCGGGGCTGACCTCGACAGGCATGAATGTGCTTTTGCTGGGGCCCGTGCCA
ACGCCTGCCGTGGGTCTGATGACCCGCTCGATGCGGGCAGATTTGGGCGTGATGATCTCTGCCAGCCACAACCCGGCCGA
GGACAATGGCATCAAGTTCTTTGGCCCCGATGGCTATAAGCTCTCGGATGAGGTGGAACTGGAGCTTGAGGCGCTGATTG
AGGCGGGTGTCGAGCCTGCACAGGCGCAGAACATTGGTCGCGCCAAACGGATCGATGATGCACGGTTTCGCTATGGCGAG
CGGGTCAAGAGCTCTTTGCCGCGTGACATGCGTCTGGATGGCCTGAAGGTTGTGATCGATTGCGCGAATGGGGCCGCCCA
CCGCGCCGCGCCTGAAATCCTGTGGGAGCTGGGTGCAGATGTGATCCCCGTCGGGGTGTCGCCCGATGGGCTCAATATCA
ATCGCGGCTGTGGCTCCACCCAGCCGGCGGCGGCGGCCGAGACGGTGGTGGCGCATGGTGCCGATGTGGGGATCTGCCTT
GACGGTGATGCCGACAGGGTTGTGGTGATCGACGAGACCGGCACCGTCGCCGACGGCGATCAGCTGATGGCGCTTCTGGC
CTCGGCATGGTCTGCGGATGGGCGGTTGAGCGGCGGCGCACTTGTTGCAACCGTCATGTCGAACCTGGGTCTCGAGCGGT
TCTTGAATGAGCGCGGCATCGGTCTTGAGCGGACCGGCGTTGGGGACCGCTATGTGGTGGAGCGCATGCGGCAGGGGGGC
TTTAACCTCGGCGGTGAGCAATCCGGCCATATCGTGATGAGCGATTATGCCACCACCGGCGACGGTCTGATGGCGGGGCT
GCATTTCCTCGCCGAGATGGTACGGCGCGGGCAGAAGGCCTCGGAATTGGCGCGCCAGTTTGAGCCGGTTCCGCAGCTGC
TCAAGAATGTGCGGTTCGAGGCCGGGCAGGCACCATTGGAGGCGGATCAGGTGCAAACGGCGATTGCAGAGGCTGAAAAG
CAGCTCAATGGCCGCGGGCGGCTGTTGATCCGAAAGTCTGGCACCGAGCCGCTCATCCGCGTGATGGCCGAGAGCGAGGA
CCCGGTGTTGCTGAACCGTGCTGTCGACGATGTGGTTGCGGCTGTAGAGGCGGCAACGCAGTAG

Upstream 100 bases:

>100_bases
GACGGCGCAGGCGCTGCGCCTGTGGCAGGCCACACGATAGAAAGAGATCACGGCAGCAGTTGGAATGTCCGGCGCTGCGC
TGGGCAGGGGAGCAGCTTTG

Downstream 100 bases:

>100_bases
GCACATGCGGCCCGGGCTTACGGTCGGCGGCGCAGGGTTTGCTTTGGTCCCTTCATGGGGGGCTCTGTCTCCACAGGCAG
AGTCGTCACCCCGAGATCTT

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MRKLFGTDGVRGKANMHPMTAEMALRIGAAVGRYFRRENDTVHRVVIGKDTRLSGYMFENALTAGLTSTGMNVLLLGPVP
TPAVGLMTRSMRADLGVMISASHNPAEDNGIKFFGPDGYKLSDEVELELEALIEAGVEPAQAQNIGRAKRIDDARFRYGE
RVKSSLPRDMRLDGLKVVIDCANGAAHRAAPEILWELGADVIPVGVSPDGLNINRGCGSTQPAAAAETVVAHGADVGICL
DGDADRVVVIDETGTVADGDQLMALLASAWSADGRLSGGALVATVMSNLGLERFLNERGIGLERTGVGDRYVVERMRQGG
FNLGGEQSGHIVMSDYATTGDGLMAGLHFLAEMVRRGQKASELARQFEPVPQLLKNVRFEAGQAPLEADQVQTAIAEAEK
QLNGRGRLLIRKSGTEPLIRVMAESEDPVLLNRAVDDVVAAVEAATQ

Sequences:

>Translated_447_residues
MRKLFGTDGVRGKANMHPMTAEMALRIGAAVGRYFRRENDTVHRVVIGKDTRLSGYMFENALTAGLTSTGMNVLLLGPVP
TPAVGLMTRSMRADLGVMISASHNPAEDNGIKFFGPDGYKLSDEVELELEALIEAGVEPAQAQNIGRAKRIDDARFRYGE
RVKSSLPRDMRLDGLKVVIDCANGAAHRAAPEILWELGADVIPVGVSPDGLNINRGCGSTQPAAAAETVVAHGADVGICL
DGDADRVVVIDETGTVADGDQLMALLASAWSADGRLSGGALVATVMSNLGLERFLNERGIGLERTGVGDRYVVERMRQGG
FNLGGEQSGHIVMSDYATTGDGLMAGLHFLAEMVRRGQKASELARQFEPVPQLLKNVRFEAGQAPLEADQVQTAIAEAEK
QLNGRGRLLIRKSGTEPLIRVMAESEDPVLLNRAVDDVVAAVEAATQ
>Mature_447_residues
MRKLFGTDGVRGKANMHPMTAEMALRIGAAVGRYFRRENDTVHRVVIGKDTRLSGYMFENALTAGLTSTGMNVLLLGPVP
TPAVGLMTRSMRADLGVMISASHNPAEDNGIKFFGPDGYKLSDEVELELEALIEAGVEPAQAQNIGRAKRIDDARFRYGE
RVKSSLPRDMRLDGLKVVIDCANGAAHRAAPEILWELGADVIPVGVSPDGLNINRGCGSTQPAAAAETVVAHGADVGICL
DGDADRVVVIDETGTVADGDQLMALLASAWSADGRLSGGALVATVMSNLGLERFLNERGIGLERTGVGDRYVVERMRQGG
FNLGGEQSGHIVMSDYATTGDGLMAGLHFLAEMVRRGQKASELARQFEPVPQLLKNVRFEAGQAPLEADQVQTAIAEAEK
QLNGRGRLLIRKSGTEPLIRVMAESEDPVLLNRAVDDVVAAVEAATQ

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=444, Percent_Identity=47.7477477477478, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1788361, Length=470, Percent_Identity=28.936170212766, Blast_Score=124, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6323934, Length=144, Percent_Identity=30.5555555555556, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_SILST (Q1GE79)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_614299.1
- ProteinModelPortal:   Q1GE79
- SMR:   Q1GE79
- STRING:   Q1GE79
- GeneID:   4078295
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_2305
- NMPDR:   fig|292414.1.peg.667
- eggNOG:   COG1109
- HOGENOM:   HBG644964
- OMA:   EEAGINS
- PhylomeDB:   Q1GE79
- ProtClustDB:   PRK14315
- BioCyc:   SSP292414:TM1040_2305-MONOMER
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47666; Mature: 47666

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLFGTDGVRGKANMHPMTAEMALRIGAAVGRYFRRENDTVHRVVIGKDTRLSGYMFEN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
ALTAGLTSTGMNVLLLGPVPTPAVGLMTRSMRADLGVMISASHNPAEDNGIKFFGPDGYK
HHHHCHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCC
LSDEVELELEALIEAGVEPAQAQNIGRAKRIDDARFRYGERVKSSLPRDMRLDGLKVVID
CCCHHHHHHHHHHHCCCCHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEE
CANGAAHRAAPEILWELGADVIPVGVSPDGLNINRGCGSTQPAAAAETVVAHGADVGICL
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEECCCCCCCCCCHHHHHHHHCCCCEEEEE
DGDADRVVVIDETGTVADGDQLMALLASAWSADGRLSGGALVATVMSNLGLERFLNERGI
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHCCC
GLERTGVGDRYVVERMRQGGFNLGGEQSGHIVMSDYATTGDGLMAGLHFLAEMVRRGQKA
CEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHH
SELARQFEPVPQLLKNVRFEAGQAPLEADQVQTAIAEAEKQLNGRGRLLIRKSGTEPLIR
HHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
VMAESEDPVLLNRAVDDVVAAVEAATQ
HHHCCCCCEEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRKLFGTDGVRGKANMHPMTAEMALRIGAAVGRYFRRENDTVHRVVIGKDTRLSGYMFEN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHH
ALTAGLTSTGMNVLLLGPVPTPAVGLMTRSMRADLGVMISASHNPAEDNGIKFFGPDGYK
HHHHCHHHCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEECCCCCC
LSDEVELELEALIEAGVEPAQAQNIGRAKRIDDARFRYGERVKSSLPRDMRLDGLKVVID
CCCHHHHHHHHHHHCCCCHHHHHCCCCHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEE
CANGAAHRAAPEILWELGADVIPVGVSPDGLNINRGCGSTQPAAAAETVVAHGADVGICL
CCCCCCHHHHHHHHHHCCCCEEEECCCCCCCEECCCCCCCCCCHHHHHHHHCCCCEEEEE
DGDADRVVVIDETGTVADGDQLMALLASAWSADGRLSGGALVATVMSNLGLERFLNERGI
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHCCC
GLERTGVGDRYVVERMRQGGFNLGGEQSGHIVMSDYATTGDGLMAGLHFLAEMVRRGQKA
CEEECCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHH
SELARQFEPVPQLLKNVRFEAGQAPLEADQVQTAIAEAEKQLNGRGRLLIRKSGTEPLIR
HHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
VMAESEDPVLLNRAVDDVVAAVEAATQ
HHHCCCCCEEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA