Click here to switch to the map view.

The map label for this gene is glpR [H]

Identifier: 99082045

GI number: 99082045

Start: 2315748

End: 2316542

Strand: Direct

Name: glpR [H]

Synonym: TM1040_2205

Alternate gene names: 99082045

Gene position: 2315748-2316542 (Clockwise)

Preceding gene: 99082044

Following gene: 99082046

Centisome position: 72.35

GC content: 62.39

Gene sequence:

>795_bases
ATGGACGCCAACGACCGCCAAAACGAAATCCTTTCCTTGCTGACCCAGCAGGATCGCGTCGAGGTCGAAGACCTCGCGCA
GCGCTTTGGCGTATCCTTGCAGACGGTGCGAACAGACTTGCGTGACCTCTCTGCCCGAGGGCAGCTCAGCCGCGTGCATG
GCGGCGCGATGCGCATCAGCTCGGCGTCAAATCGCGGCTATGCCGAACGGCGCAGCCTCAACGCGACCGGCAAGCGCGCG
ATGGCAGCTCTGGCGGCTGAGGTGATCCCGGAAAACTGCTCCATCGCGCTCAATATCGGCACCTCCACCGAACAGGTCGC
GCGTGCACTCTCTGGCCACAAGGGCCTCACGGTGCTCTCAAACAACATCAACATTATCAATATGATGATGGAAATGGAGA
CGCGTGACCTGATCCTTGTTGGCGGCTCCATCCGGCAAAGCGACGGCGCCATCGTCGGCGAAGAGGCCGTCGAGTTCATC
AATCGATACAAGGTCGATTACGCCGTGATCGGCGCCTCTGCCATGGACGCCGACGGTGCCATCCTCGACCACGACGCGCG
CGAAGTATCCGTCGCCCGCGCGATCCTCAAAAACGCCCGCACGCGCATCCTGATGTGCGACGGCAGCAAATTCGACCGCT
CTGCCCCAGTGCGCATCTGCGCGCTGGCCGAGCTGGACCTTGTCATCACCGACCGCCCCGTTCCCGCGGAATTTGCCGAG
GCCGCAGAGGCCGCTGGCACACGAATCCTCATCGCAGACGGCGGCGCAGAAAACGAAAGCAGCGCAAATGACTGA

Upstream 100 bases:

>100_bases
GCGAGGGGCTTTCTTTTTGATGCCACCCAATACCAAAACGAAAATCAATAGTGACAATATACCTGCATTCGCCTAAAGAT
ATTCGGGAAAAGGAAAGCAA

Downstream 100 bases:

>100_bases
TTCCTCGCAAAGCACCGAGATCACCGATCTCTTCATCATTGGCGGCGGCATCAATGGCTGTGGCATCGCGCGCGACGCAG
CAGGCCGTGGGCTTTCCGTG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MDANDRQNEILSLLTQQDRVEVEDLAQRFGVSLQTVRTDLRDLSARGQLSRVHGGAMRISSASNRGYAERRSLNATGKRA
MAALAAEVIPENCSIALNIGTSTEQVARALSGHKGLTVLSNNINIINMMMEMETRDLILVGGSIRQSDGAIVGEEAVEFI
NRYKVDYAVIGASAMDADGAILDHDAREVSVARAILKNARTRILMCDGSKFDRSAPVRICALAELDLVITDRPVPAEFAE
AAEAAGTRILIADGGAENESSAND

Sequences:

>Translated_264_residues
MDANDRQNEILSLLTQQDRVEVEDLAQRFGVSLQTVRTDLRDLSARGQLSRVHGGAMRISSASNRGYAERRSLNATGKRA
MAALAAEVIPENCSIALNIGTSTEQVARALSGHKGLTVLSNNINIINMMMEMETRDLILVGGSIRQSDGAIVGEEAVEFI
NRYKVDYAVIGASAMDADGAILDHDAREVSVARAILKNARTRILMCDGSKFDRSAPVRICALAELDLVITDRPVPAEFAE
AAEAAGTRILIADGGAENESSAND
>Mature_264_residues
MDANDRQNEILSLLTQQDRVEVEDLAQRFGVSLQTVRTDLRDLSARGQLSRVHGGAMRISSASNRGYAERRSLNATGKRA
MAALAAEVIPENCSIALNIGTSTEQVARALSGHKGLTVLSNNINIINMMMEMETRDLILVGGSIRQSDGAIVGEEAVEFI
NRYKVDYAVIGASAMDADGAILDHDAREVSVARAILKNARTRILMCDGSKFDRSAPVRICALAELDLVITDRPVPAEFAE
AAEAAGTRILIADGGAENESSAND

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=236, Percent_Identity=38.5593220338983, Blast_Score=184, Evalue=4e-48,
Organism=Escherichia coli, GI87082344, Length=236, Percent_Identity=32.6271186440678, Blast_Score=157, Evalue=8e-40,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=29.3650793650794, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789059, Length=260, Percent_Identity=30, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=28.9156626506024, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1788069, Length=240, Percent_Identity=27.5, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=27.2, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789170, Length=229, Percent_Identity=28.3842794759825, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787540, Length=252, Percent_Identity=28.1746031746032, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787063, Length=248, Percent_Identity=23.7903225806452, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=23.015873015873, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28327; Mature: 28327

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDANDRQNEILSLLTQQDRVEVEDLAQRFGVSLQTVRTDLRDLSARGQLSRVHGGAMRIS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEE
SASNRGYAERRSLNATGKRAMAALAAEVIPENCSIALNIGTSTEQVARALSGHKGLTVLS
CCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEE
NNINIINMMMEMETRDLILVGGSIRQSDGAIVGEEAVEFINRYKVDYAVIGASAMDADGA
CCCEEEEEEEHHCCCCEEEECCCEECCCCCEECHHHHHHHHHHCCEEEEEECCCCCCCCC
ILDHDAREVSVARAILKNARTRILMCDGSKFDRSAPVRICALAELDLVITDRPVPAEFAE
EECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHH
AAEAAGTRILIADGGAENESSAND
HHHHCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MDANDRQNEILSLLTQQDRVEVEDLAQRFGVSLQTVRTDLRDLSARGQLSRVHGGAMRIS
CCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHCCCEEEEE
SASNRGYAERRSLNATGKRAMAALAAEVIPENCSIALNIGTSTEQVARALSGHKGLTVLS
CCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCCCCEEEEE
NNINIINMMMEMETRDLILVGGSIRQSDGAIVGEEAVEFINRYKVDYAVIGASAMDADGA
CCCEEEEEEEHHCCCCEEEECCCEECCCCCEECHHHHHHHHHHCCEEEEEECCCCCCCCC
ILDHDAREVSVARAILKNARTRILMCDGSKFDRSAPVRICALAELDLVITDRPVPAEFAE
EECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEEEEEEEEEEECCCCCHHHHH
AAEAAGTRILIADGGAENESSAND
HHHHCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]