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The map label for this gene is blc [H]

Identifier: 99082027

GI number: 99082027

Start: 2297086

End: 2297646

Strand: Reverse

Name: blc [H]

Synonym: TM1040_2187

Alternate gene names: 99082027

Gene position: 2297646-2297086 (Counterclockwise)

Preceding gene: 99082028

Following gene: 99082026

Centisome position: 71.78

GC content: 62.21

Gene sequence:

>561_bases
ATGATTGCAGTTGCTTTTCGCTCCACACTCGCCGCCACCCTGGTTGCTCTTACACTCGCGGCACCGGTGCAGGCTGCAGA
GTATCGCGACACCGATGTTGCGATGACCGTGCAAGAGGATCTGGACCTGTCGCGCTATCTTGGCACTTGGTACGAGATCG
CGCGGTTTCCCAACCGGTTTGAGCAGGGCTGTGCGGCGGTGACCGCAGAGTACAGCCCGCTTCCCAAGGATCGCATCAAG
GTGGTGAACAGCTGTCGCAAGGGGGGCGTGACGGGACCGCTGGAAACGGTCGAAGGCGTGGCGCGCGTCGCGGGGCCTGG
CAAGCTTGAGGTGAACTTTGTCTCCTGGTTGCGGCTCTTGCCCTTCACATGGGGGGACTACTGGGTGCTGGACGTGGACG
CGGACTATCAGGTGGCGGTCATCGGCACGCCAAAAGGCAAGCAGGGCTGGATTCTGGCCCGCACGCCCAACATCAGCGCG
ACAGAGCTGGAGGCTGCAAAAGCGGTCCTGCGCAAGAATGGATATGACACCGGGGCCCTGGAGATGGTGCCCCAGAACTA
G

Upstream 100 bases:

>100_bases
TTGGCCTGCAGAAACGCGCCCCGATCACCAAGTAATCGGGAACGAAAGCCGGGGGCAGGGGTTAGAGTTGAAAGATATTT
TGCCCCCGGAGGTCCGTATC

Downstream 100 bases:

>100_bases
GGACAACGGGATATGACAAAAACAGCAGCAATCATTGGCGGTGGCGTTATCGGCGGCGGTTGGGCCGCGCGGTTCTTGCT
CAATGGCTGGGATGTGCGGG

Product: Lipocalin-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MIAVAFRSTLAATLVALTLAAPVQAAEYRDTDVAMTVQEDLDLSRYLGTWYEIARFPNRFEQGCAAVTAEYSPLPKDRIK
VVNSCRKGGVTGPLETVEGVARVAGPGKLEVNFVSWLRLLPFTWGDYWVLDVDADYQVAVIGTPKGKQGWILARTPNISA
TELEAAKAVLRKNGYDTGALEMVPQN

Sequences:

>Translated_186_residues
MIAVAFRSTLAATLVALTLAAPVQAAEYRDTDVAMTVQEDLDLSRYLGTWYEIARFPNRFEQGCAAVTAEYSPLPKDRIK
VVNSCRKGGVTGPLETVEGVARVAGPGKLEVNFVSWLRLLPFTWGDYWVLDVDADYQVAVIGTPKGKQGWILARTPNISA
TELEAAKAVLRKNGYDTGALEMVPQN
>Mature_186_residues
MIAVAFRSTLAATLVALTLAAPVQAAEYRDTDVAMTVQEDLDLSRYLGTWYEIARFPNRFEQGCAAVTAEYSPLPKDRIK
VVNSCRKGGVTGPLETVEGVARVAGPGKLEVNFVSWLRLLPFTWGDYWVLDVDADYQVAVIGTPKGKQGWILARTPNISA
TELEAAKAVLRKNGYDTGALEMVPQN

Specific function: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids [H]

COG id: COG3040

COG function: function code M; Bacterial lipocalin

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the calycin superfamily. Lipocalin family [H]

Homologues:

Organism=Homo sapiens, GI4502163, Length=156, Percent_Identity=32.0512820512821, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1790592, Length=155, Percent_Identity=36.7741935483871, Blast_Score=83, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28574799, Length=141, Percent_Identity=34.7517730496454, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR013208
- InterPro:   IPR022271
- InterPro:   IPR002446
- InterPro:   IPR022272 [H]

Pfam domain/function: PF08212 Lipocalin_2 [H]

EC number: NA

Molecular weight: Translated: 20307; Mature: 20307

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVAFRSTLAATLVALTLAAPVQAAEYRDTDVAMTVQEDLDLSRYLGTWYEIARFPNRF
CEEEHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCHHHH
EQGCAAVTAEYSPLPKDRIKVVNSCRKGGVTGPLETVEGVARVAGPGKLEVNFVSWLRLL
HHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHH
PFTWGDYWVLDVDADYQVAVIGTPKGKQGWILARTPNISATELEAAKAVLRKNGYDTGAL
CCCCCCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEE
EMVPQN
EEECCC
>Mature Secondary Structure
MIAVAFRSTLAATLVALTLAAPVQAAEYRDTDVAMTVQEDLDLSRYLGTWYEIARFPNRF
CEEEHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEEHHHCCHHHHHHHHHHHHHCHHHH
EQGCAAVTAEYSPLPKDRIKVVNSCRKGGVTGPLETVEGVARVAGPGKLEVNFVSWLRLL
HHHHHEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHH
PFTWGDYWVLDVDADYQVAVIGTPKGKQGWILARTPNISATELEAAKAVLRKNGYDTGAL
CCCCCCEEEEEECCCEEEEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCCCEE
EMVPQN
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]