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The map label for this gene is gmr [H]

Identifier: 99082009

GI number: 99082009

Start: 2281704

End: 2282726

Strand: Reverse

Name: gmr [H]

Synonym: TM1040_2169

Alternate gene names: 99082009

Gene position: 2282726-2281704 (Counterclockwise)

Preceding gene: 99082010

Following gene: 99082008

Centisome position: 71.31

GC content: 59.24

Gene sequence:

>1023_bases
ATGATGACCTTCGAACAGCTGACCGGCCTTGCCGACCAACTCTGCCCAATGCATGTGATCATTGACGCGGATGGCCTGAT
CGTGAGCCACGGTCCGACCCTCGACAAGATCCGGGGCGACAATGGCTGGTTGGGCAAACCGGTGCTCGAGGTGCTGGACC
TGCAGCGGCCTCGCTCCGTCAAAGCCGTTGCTGATCTCATGAATACCGCTGGCAGCAAACTGCACTTTCAGCTTCATGAC
GCGCCGCACACCCGGATGAAGGGCGTGTTGGTTCCGCTCCCCAAGGGGCGGGGCGCATTCATAAATCTCTCTTTCGGGAT
TTCGGTGCTGGATGCGGTGCGCGACTTCAACCTGACCAGTCAGGATTTCTCGCCCACGGATCTCACGATCGAGATGCTTT
ACCTGGTGGAGGCGAAATCTGCCGCTATGGAGGCGTCGCGCCAGCTGAACCTGCGCTTGCAGGGGGCCAAGATTGCCGCC
GAGGAGCAGGCCTTTACCGATACGTTGACCGGGCTGAAGAACCGTCGCGCCATGGACCATGTGTTGAACCGCCTGATCAG
CGGCGGGCGCGACTTTGCCCTGATGAATGTCGATCTCGACTTCTTCAAATCTGTCAATGACACCTACGGTCATGCCGCAG
GTGATGCGGTGTTGCAGCGGGTGGCCTCCATCATGGTGGAGTGTACACGCAAATCTGACACCGTTGCGCGCATCGGTGGT
GACGAGTTTGTGCTGGTGTTTGAGGGGTTGATGGATCGCAACCGGATCAATGATCTGGCCTGCCGCCTGATCGAGCGCCT
TGAAGAGCCGATCATGTATGGCGCGGATGAGTGCCGGATTTCCGCCTCTGCAGGCACCACCTTGTCCACGGATGTCGCGC
AGCCTCTGCCGGCGACGCTATTGCATCAGGCCGACCTTGCGCTCTACGCCTCCAAACGGGCGGGCAAAGCGCAGCATATG
TTCTATACGCCCAGCCTCGAAGATGAGATGGATCTGGTCGAGCAAAACAGCAAGTCTGCCTGA

Upstream 100 bases:

>100_bases
ATCTCGTGGGGGAGCAGGAAGGCTCCGACGTGATTTCGATCACCCTCGTGGAAAGCGATTTCAGCGAGGGGCGCGCGTTT
GAACTGGGGGCGCATACATT

Downstream 100 bases:

>100_bases
CAGCGCACATACCTCTCCGCGGCGCCGCTTTCGCGCAAAGGGTTTCTGGCCCATACGGATTTCTTCCGTGTGGGCCTTTT
CGATTTGGCATGGCTCGAAG

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MMTFEQLTGLADQLCPMHVIIDADGLIVSHGPTLDKIRGDNGWLGKPVLEVLDLQRPRSVKAVADLMNTAGSKLHFQLHD
APHTRMKGVLVPLPKGRGAFINLSFGISVLDAVRDFNLTSQDFSPTDLTIEMLYLVEAKSAAMEASRQLNLRLQGAKIAA
EEQAFTDTLTGLKNRRAMDHVLNRLISGGRDFALMNVDLDFFKSVNDTYGHAAGDAVLQRVASIMVECTRKSDTVARIGG
DEFVLVFEGLMDRNRINDLACRLIERLEEPIMYGADECRISASAGTTLSTDVAQPLPATLLHQADLALYASKRAGKAQHM
FYTPSLEDEMDLVEQNSKSA

Sequences:

>Translated_340_residues
MMTFEQLTGLADQLCPMHVIIDADGLIVSHGPTLDKIRGDNGWLGKPVLEVLDLQRPRSVKAVADLMNTAGSKLHFQLHD
APHTRMKGVLVPLPKGRGAFINLSFGISVLDAVRDFNLTSQDFSPTDLTIEMLYLVEAKSAAMEASRQLNLRLQGAKIAA
EEQAFTDTLTGLKNRRAMDHVLNRLISGGRDFALMNVDLDFFKSVNDTYGHAAGDAVLQRVASIMVECTRKSDTVARIGG
DEFVLVFEGLMDRNRINDLACRLIERLEEPIMYGADECRISASAGTTLSTDVAQPLPATLLHQADLALYASKRAGKAQHM
FYTPSLEDEMDLVEQNSKSA
>Mature_340_residues
MMTFEQLTGLADQLCPMHVIIDADGLIVSHGPTLDKIRGDNGWLGKPVLEVLDLQRPRSVKAVADLMNTAGSKLHFQLHD
APHTRMKGVLVPLPKGRGAFINLSFGISVLDAVRDFNLTSQDFSPTDLTIEMLYLVEAKSAAMEASRQLNLRLQGAKIAA
EEQAFTDTLTGLKNRRAMDHVLNRLISGGRDFALMNVDLDFFKSVNDTYGHAAGDAVLQRVASIMVECTRKSDTVARIGG
DEFVLVFEGLMDRNRINDLACRLIERLEEPIMYGADECRISASAGTTLSTDVAQPLPATLLHQADLALYASKRAGKAQHM
FYTPSLEDEMDLVEQNSKSA

Specific function: Part of a 2 protein system that seems to be dedicated to transcription of csgD. This protein decreases csgD transcription and thus decreases expression of adhesive curli fimbriae genes csgEFG, csgBAC/ymaD and adrA (yaic). Activity of this protein is antag

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=167, Percent_Identity=36.5269461077844, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788381, Length=187, Percent_Identity=35.8288770053476, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=32.9268292682927, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87082007, Length=162, Percent_Identity=35.8024691358025, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081881, Length=164, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786584, Length=161, Percent_Identity=32.2981366459627, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=180, Percent_Identity=30, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87081974, Length=124, Percent_Identity=33.0645161290323, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788956, Length=169, Percent_Identity=29.585798816568, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=31.875, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787056, Length=156, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=29.940119760479, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR000014
- InterPro:   IPR013767 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF00989 PAS [H]

EC number: =3.1.4.52 [H]

Molecular weight: Translated: 37316; Mature: 37316

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTFEQLTGLADQLCPMHVIIDADGLIVSHGPTLDKIRGDNGWLGKPVLEVLDLQRPRSV
CCCHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHCCCCCCCCCHHHHHHHCCCCCCHH
KAVADLMNTAGSKLHFQLHDAPHTRMKGVLVPLPKGRGAFINLSFGISVLDAVRDFNLTS
HHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHHCCCCC
QDFSPTDLTIEMLYLVEAKSAAMEASRQLNLRLQGAKIAAEEQAFTDTLTGLKNRRAMDH
CCCCCCCCEEEEEEEHHHHHHHHHHHHHEEEEEECCEECHHHHHHHHHHHHHHHHHHHHH
VLNRLISGGRDFALMNVDLDFFKSVNDTYGHAAGDAVLQRVASIMVECTRKSDTVARIGG
HHHHHHCCCCCEEEEECCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECC
DEFVLVFEGLMDRNRINDLACRLIERLEEPIMYGADECRISASAGTTLSTDVAQPLPATL
CCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCEECCHHCCCCCHHH
LHQADLALYASKRAGKAQHMFYTPSLEDEMDLVEQNSKSA
HHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCCCC
>Mature Secondary Structure
MMTFEQLTGLADQLCPMHVIIDADGLIVSHGPTLDKIRGDNGWLGKPVLEVLDLQRPRSV
CCCHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHCCCCCCCCCHHHHHHHCCCCCCHH
KAVADLMNTAGSKLHFQLHDAPHTRMKGVLVPLPKGRGAFINLSFGISVLDAVRDFNLTS
HHHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEEEECCHHHHHHHHHCCCCC
QDFSPTDLTIEMLYLVEAKSAAMEASRQLNLRLQGAKIAAEEQAFTDTLTGLKNRRAMDH
CCCCCCCCEEEEEEEHHHHHHHHHHHHHEEEEEECCEECHHHHHHHHHHHHHHHHHHHHH
VLNRLISGGRDFALMNVDLDFFKSVNDTYGHAAGDAVLQRVASIMVECTRKSDTVARIGG
HHHHHHCCCCCEEEEECCHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECC
DEFVLVFEGLMDRNRINDLACRLIERLEEPIMYGADECRISASAGTTLSTDVAQPLPATL
CCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHEEECCCCCEECCHHCCCCCHHH
LHQADLALYASKRAGKAQHMFYTPSLEDEMDLVEQNSKSA
HHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]