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The map label for this gene is mocR [H]

Identifier: 99082007

GI number: 99082007

Start: 2277923

End: 2279320

Strand: Reverse

Name: mocR [H]

Synonym: TM1040_2167

Alternate gene names: 99082007

Gene position: 2279320-2277923 (Counterclockwise)

Preceding gene: 99082008

Following gene: 99082002

Centisome position: 71.21

GC content: 65.16

Gene sequence:

>1398_bases
ATGCCAAGCGATTTGCCCGCCTTTATGCCGGATCGGCGTTCTGATGTGCCGATCTTTGAGCAGATCTGCACGGCCTTGCG
ATCTCGAATTCGCTCTGGGGCTCTTGCCACCGGGGCGCGGCTCCCGGCAACGCGGGCGCTTGCAGGGGATCTGGGGGTGG
CGCGTGCGACGGTCGTGACGGCCTATGAGCAGCTGGTGGCCGAGGGCTATCTCATGGCGCGGCGCGGATCGGGTTATACC
GTCTGTGCCATGGGCGAGGTGGAGCTTCCGGCGAAAGGGACGCCCACGCCACCTGCGGACCTCAGCGAGCGGGGAGACCT
GCTCTTGGAGGCTGGCCAGCCGGACATGCGTCTCTTTCCGCACCGCGCCTGGGCAAAAGCCGTTGCTCGCCTCTGCCGCA
CACGTCCAGAAGATATGTTGATGGGCTGCGGGCGCTTTGGTCATCCGGACCTGCGCCAGGCCATTGCCGCCCATGTGAAC
GATTGGCGCGGGATCGCCGCGCGGCCGGATCAGGTGCTGGTCACCTCTGGCGCGACCGAGGCGTTGGATGTTTGTCTCGC
GGCGCTGGCCTCGAGCACCGGAGCGGTTGGGGTGGAGGATCCCGGCTATCCCCCGATCCGACGGTTTGCGCAGGCGCAGG
GGCGTCGCATCCGAGACTTGGCGCTCGATTCCCAAGGGGCCGAAGTCCCTACAACTGGCGATGGCACCGATGTGGTGGTT
CTGACGCCGTCGCATCAATACCCGCTTGGTGGCGCGATGAGTGCGGGCCGGCGACAAGAGTTTGTGCGCTGGGCGGCGCA
GTCACAGGGCTGGATCATCGAGGACGATTACGATTCGGAATTTCGCTATGCGGGCCGACCGATTCCCGCGCTGGCAGGTG
TCGACGGGCAGGGGCGGACAGTCTACATCGGCAGCTTCTCCAAGATTTTCTCGAACAGCTTGCGGATGGGGTACATCGTG
GCCCCCGAGGCGCTGGTGGAGCGCCTCGTGCGGGCGATGCGTCGCAAGGGTGCGCGTGCCAGTGCCATGCCCCAAGCGGC
TCTGGCGGAGTTTATGCAGCACGGAGAGTTCTACCGGCACCTGCGCCGGGTGCGCCGAATCTATGCGGAACGGCACCGGA
CCCTGATCGCGCGGTTGCGCTCGGATTTCTCTGATGTGGGCCATGTGGAGGATTATCAAGCTGGCATGCAGGTCGTGCTG
CATCTGCGTCCCGAAATTTGCGATCAGACCGTGACAACAGCCGCACGCGCAGCCGGTGTGGGTGCGGAGGCGCTCTCAAG
CTACAGCCGCCGCGCGGGCGCCTTCAATGGGGTGGTTCTGGGCGCCTGCCTCAATGATCTTGATGAGCAGGCAGAAGCCC
TGTCGCGCCTGCGCGCGACGATTTCCTCAACAGGATAA

Upstream 100 bases:

>100_bases
TCTGGGAAAGACAGGGGCCGGGCGTTGTGCCCGGTCTTTGCTTGTCTGTCGATTGGCGCAGGCATAACGTTGCCAAGAGG
ACACTCTGATCGGACCAATT

Downstream 100 bases:

>100_bases
TCCCCTGCTTCTCGGCGGTGCGTGAGTGGTGGAATGCGCCAATTTTTCAGAGAGAAAAATGGTACTCCGTAGGGGAATCG
AACCCCTCTTTCCAGGTTGA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MPSDLPAFMPDRRSDVPIFEQICTALRSRIRSGALATGARLPATRALAGDLGVARATVVTAYEQLVAEGYLMARRGSGYT
VCAMGEVELPAKGTPTPPADLSERGDLLLEAGQPDMRLFPHRAWAKAVARLCRTRPEDMLMGCGRFGHPDLRQAIAAHVN
DWRGIAARPDQVLVTSGATEALDVCLAALASSTGAVGVEDPGYPPIRRFAQAQGRRIRDLALDSQGAEVPTTGDGTDVVV
LTPSHQYPLGGAMSAGRRQEFVRWAAQSQGWIIEDDYDSEFRYAGRPIPALAGVDGQGRTVYIGSFSKIFSNSLRMGYIV
APEALVERLVRAMRRKGARASAMPQAALAEFMQHGEFYRHLRRVRRIYAERHRTLIARLRSDFSDVGHVEDYQAGMQVVL
HLRPEICDQTVTTAARAAGVGAEALSSYSRRAGAFNGVVLGACLNDLDEQAEALSRLRATISSTG

Sequences:

>Translated_465_residues
MPSDLPAFMPDRRSDVPIFEQICTALRSRIRSGALATGARLPATRALAGDLGVARATVVTAYEQLVAEGYLMARRGSGYT
VCAMGEVELPAKGTPTPPADLSERGDLLLEAGQPDMRLFPHRAWAKAVARLCRTRPEDMLMGCGRFGHPDLRQAIAAHVN
DWRGIAARPDQVLVTSGATEALDVCLAALASSTGAVGVEDPGYPPIRRFAQAQGRRIRDLALDSQGAEVPTTGDGTDVVV
LTPSHQYPLGGAMSAGRRQEFVRWAAQSQGWIIEDDYDSEFRYAGRPIPALAGVDGQGRTVYIGSFSKIFSNSLRMGYIV
APEALVERLVRAMRRKGARASAMPQAALAEFMQHGEFYRHLRRVRRIYAERHRTLIARLRSDFSDVGHVEDYQAGMQVVL
HLRPEICDQTVTTAARAAGVGAEALSSYSRRAGAFNGVVLGACLNDLDEQAEALSRLRATISSTG
>Mature_464_residues
PSDLPAFMPDRRSDVPIFEQICTALRSRIRSGALATGARLPATRALAGDLGVARATVVTAYEQLVAEGYLMARRGSGYTV
CAMGEVELPAKGTPTPPADLSERGDLLLEAGQPDMRLFPHRAWAKAVARLCRTRPEDMLMGCGRFGHPDLRQAIAAHVND
WRGIAARPDQVLVTSGATEALDVCLAALASSTGAVGVEDPGYPPIRRFAQAQGRRIRDLALDSQGAEVPTTGDGTDVVVL
TPSHQYPLGGAMSAGRRQEFVRWAAQSQGWIIEDDYDSEFRYAGRPIPALAGVDGQGRTVYIGSFSKIFSNSLRMGYIVA
PEALVERLVRAMRRKGARASAMPQAALAEFMQHGEFYRHLRRVRRIYAERHRTLIARLRSDFSDVGHVEDYQAGMQVVLH
LRPEICDQTVTTAARAAGVGAEALSSYSRRAGAFNGVVLGACLNDLDEQAEALSRLRATISSTG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=224, Percent_Identity=23.6607142857143, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI33469970, Length=224, Percent_Identity=23.6607142857143, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787710, Length=405, Percent_Identity=28.3950617283951, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1790797, Length=394, Percent_Identity=24.6192893401015, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 50346; Mature: 50215

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSDLPAFMPDRRSDVPIFEQICTALRSRIRSGALATGARLPATRALAGDLGVARATVVT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHH
AYEQLVAEGYLMARRGSGYTVCAMGEVELPAKGTPTPPADLSERGDLLLEAGQPDMRLFP
HHHHHHHCCHHEEECCCCEEEEEECCEECCCCCCCCCCCCCCCCCCEEEECCCCCCHHCC
HRAWAKAVARLCRTRPEDMLMGCGRFGHPDLRQAIAAHVNDWRGIAARPDQVLVTSGATE
HHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHH
ALDVCLAALASSTGAVGVEDPGYPPIRRFAQAQGRRIRDLALDSQGAEVPTTGDGTDVVV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCEEEE
LTPSHQYPLGGAMSAGRRQEFVRWAAQSQGWIIEDDYDSEFRYAGRPIPALAGVDGQGRT
ECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHCCCCCCHHCCCCCCCCE
VYIGSFSKIFSNSLRMGYIVAPEALVERLVRAMRRKGARASAMPQAALAEFMQHGEFYRH
EEEECHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LRRVRRIYAERHRTLIARLRSDFSDVGHVEDYQAGMQVVLHLRPEICDQTVTTAARAAGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
GAEALSSYSRRAGAFNGVVLGACLNDLDEQAEALSRLRATISSTG
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSDLPAFMPDRRSDVPIFEQICTALRSRIRSGALATGARLPATRALAGDLGVARATVVT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHH
AYEQLVAEGYLMARRGSGYTVCAMGEVELPAKGTPTPPADLSERGDLLLEAGQPDMRLFP
HHHHHHHCCHHEEECCCCEEEEEECCEECCCCCCCCCCCCCCCCCCEEEECCCCCCHHCC
HRAWAKAVARLCRTRPEDMLMGCGRFGHPDLRQAIAAHVNDWRGIAARPDQVLVTSGATE
HHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCHH
ALDVCLAALASSTGAVGVEDPGYPPIRRFAQAQGRRIRDLALDSQGAEVPTTGDGTDVVV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCEEEE
LTPSHQYPLGGAMSAGRRQEFVRWAAQSQGWIIEDDYDSEFRYAGRPIPALAGVDGQGRT
ECCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCHHHCCCCCCHHCCCCCCCCE
VYIGSFSKIFSNSLRMGYIVAPEALVERLVRAMRRKGARASAMPQAALAEFMQHGEFYRH
EEEECHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
LRRVRRIYAERHRTLIARLRSDFSDVGHVEDYQAGMQVVLHLRPEICDQTVTTAARAAGV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCC
GAEALSSYSRRAGAFNGVVLGACLNDLDEQAEALSRLRATISSTG
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]