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The map label for this gene is ctrA [H]

Identifier: 99081973

GI number: 99081973

Start: 2238343

End: 2239470

Strand: Direct

Name: ctrA [H]

Synonym: TM1040_2133

Alternate gene names: 99081973

Gene position: 2238343-2239470 (Clockwise)

Preceding gene: 99081972

Following gene: 99081974

Centisome position: 69.93

GC content: 62.41

Gene sequence:

>1128_bases
ATGACTTTACGGTGGGCGCGCCCCGTGGCCTTGTTGGCTGCGGTTGCCCTCGCAGCATCATGCGGGCTGCCCAAGGTGGG
CCCGAACAAACGTGAGATCTTTGCAGGGTCGGTACAAAAACAGGGCGATGCCTTTGTGGTCTCGGTCAACGACCGCGTTG
CCCGGGCAACAGCCGTGGTACCCGCACTTGGGTTTTCCGACGCCTTCACCAAAGCATCGGTTCTTACCTCCGACATCATT
CGCCCCGGCGATATCCTTGGCCTGACGATCTGGGAAAACGTCGACGACGGGCTGCTTGCCAGCGCCGGCGCCAATGCCAC
CCTTCTCGAAGAAGTGCAGGTTGATGGTGCGGGCTTCATCTTTGTGCCCTACGCAGGCCGCGTGCGCGCCTCGGGCAATA
CGCCAGAGCAGTTGCGCGAAGCCATCACCAAGAAGCTCGAAGACCAGACGCCCGACCCGCAGGTTCAGGTGCGCCGCCTT
GCCGGCGATGGCGCCACAGTCAGCCTCACCGGAGCGGTGGGCGCGCAGGGGGTCTATCCAATCGAACGTCCGACGCGCAC
TCTGGCCACCATGCTGGCGCAAGCTGGCGGCGTGGCGATCGAACCCGAGATTGCGCAGGTCTCTGTGACCCGCCAAGGGC
AGACTGGCACGATCTGGTTCGAGGACCTCTACGACCACCCCCAGATGGACATCGCGCTGCGCAATGGCGACAAGATCCTT
GTGGAAGGCGATACGCGCTCCTTTACCGCGCTGGGAGCGACCGCGGCGCAGGCCCGTGTACCTTTCGAGAGCCAGAACCT
CTCGGCGCTTGAAGCTCTTGCACAGGTCGGCGGCCTGATCGCCACGGCATCCGATCCCACCGGTGTCTTTGTCTTCCGCA
ATGAACCTGAAGCGATCTCAAATCAGGTGCTTGGGCGTGACGATCTGATCGGCGCGCAGCGCATGATCTACGTGCTGAAC
CTCACTCAGCCCAACGGTCTCTTCATTGCCCGCGACTTCGTGATCCGCGATGGCGACACCATCTATGTGACCGAAGCACC
CTATGCCCAATGGACCAAGACGCTGTCTCTTCTGACCAGCCCGCTGTCCACGGCTGCAAGTGTCGAGACCCTGTTCGGCG
GCAGTTAA

Upstream 100 bases:

>100_bases
GATGCAAGCGCGACTGGATTTTTGCGTGACAGTCCGCTAATTTGGGCGCAAAACTTGAGGCAAAATAAACATAGGTCGAG
GAGACCGAGCAGTGAAACCC

Downstream 100 bases:

>100_bases
GCAGCAATGATGCAAGGGCCTTTGCCGCATCTGGACGAGACCAGAACCGGGAGCAAACGCTCCCGGTTGTTTGTGTATAA
CGGAGGGTTTCTGACCCAGT

Product: polysaccharide export protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTLRWARPVALLAAVALAASCGLPKVGPNKREIFAGSVQKQGDAFVVSVNDRVARATAVVPALGFSDAFTKASVLTSDII
RPGDILGLTIWENVDDGLLASAGANATLLEEVQVDGAGFIFVPYAGRVRASGNTPEQLREAITKKLEDQTPDPQVQVRRL
AGDGATVSLTGAVGAQGVYPIERPTRTLATMLAQAGGVAIEPEIAQVSVTRQGQTGTIWFEDLYDHPQMDIALRNGDKIL
VEGDTRSFTALGATAAQARVPFESQNLSALEALAQVGGLIATASDPTGVFVFRNEPEAISNQVLGRDDLIGAQRMIYVLN
LTQPNGLFIARDFVIRDGDTIYVTEAPYAQWTKTLSLLTSPLSTAASVETLFGGS

Sequences:

>Translated_375_residues
MTLRWARPVALLAAVALAASCGLPKVGPNKREIFAGSVQKQGDAFVVSVNDRVARATAVVPALGFSDAFTKASVLTSDII
RPGDILGLTIWENVDDGLLASAGANATLLEEVQVDGAGFIFVPYAGRVRASGNTPEQLREAITKKLEDQTPDPQVQVRRL
AGDGATVSLTGAVGAQGVYPIERPTRTLATMLAQAGGVAIEPEIAQVSVTRQGQTGTIWFEDLYDHPQMDIALRNGDKIL
VEGDTRSFTALGATAAQARVPFESQNLSALEALAQVGGLIATASDPTGVFVFRNEPEAISNQVLGRDDLIGAQRMIYVLN
LTQPNGLFIARDFVIRDGDTIYVTEAPYAQWTKTLSLLTSPLSTAASVETLFGGS
>Mature_374_residues
TLRWARPVALLAAVALAASCGLPKVGPNKREIFAGSVQKQGDAFVVSVNDRVARATAVVPALGFSDAFTKASVLTSDIIR
PGDILGLTIWENVDDGLLASAGANATLLEEVQVDGAGFIFVPYAGRVRASGNTPEQLREAITKKLEDQTPDPQVQVRRLA
GDGATVSLTGAVGAQGVYPIERPTRTLATMLAQAGGVAIEPEIAQVSVTRQGQTGTIWFEDLYDHPQMDIALRNGDKILV
EGDTRSFTALGATAAQARVPFESQNLSALEALAQVGGLIATASDPTGVFVFRNEPEAISNQVLGRDDLIGAQRMIYVLNL
TQPNGLFIARDFVIRDGDTIYVTEAPYAQWTKTLSLLTSPLSTAASVETLFGGS

Specific function: Involved in transport of capsular polysaccharides to the cell surface. May function as a membrane anchor for capsular polysaccharides. Possible porin properties [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1787218, Length=287, Percent_Identity=27.8745644599303, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788376, Length=288, Percent_Identity=26.7361111111111, Blast_Score=91, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715 [H]

Pfam domain/function: PF02563 Poly_export [H]

EC number: NA

Molecular weight: Translated: 39637; Mature: 39506

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRWARPVALLAAVALAASCGLPKVGPNKREIFAGSVQKQGDAFVVSVNDRVARATAVV
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHH
PALGFSDAFTKASVLTSDIIRPGDILGLTIWENVDDGLLASAGANATLLEEVQVDGAGFI
CCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCEEEEEEEECCCCEE
FVPYAGRVRASGNTPEQLREAITKKLEDQTPDPQVQVRRLAGDGATVSLTGAVGAQGVYP
EEECCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCEEEEEECCCCCCCCC
IERPTRTLATMLAQAGGVAIEPEIAQVSVTRQGQTGTIWFEDLYDHPQMDIALRNGDKIL
CCCHHHHHHHHHHHCCCEEECCCEEEEEEEECCCCCEEEEHHHCCCCCEEEEEECCCEEE
VEGDTRSFTALGATAAQARVPFESQNLSALEALAQVGGLIATASDPTGVFVFRNEPEAIS
EECCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCEEEECCCCCEEEEECCCCHHHH
NQVLGRDDLIGAQRMIYVLNLTQPNGLFIARDFVIRDGDTIYVTEAPYAQWTKTLSLLTS
HHHCCCHHCCCCEEEEEEEEECCCCCEEEEEEEEEECCCEEEEECCCHHHHHHHHHHHHH
PLSTAASVETLFGGS
CHHHHHHHHHHCCCC
>Mature Secondary Structure 
TLRWARPVALLAAVALAASCGLPKVGPNKREIFAGSVQKQGDAFVVSVNDRVARATAVV
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHH
PALGFSDAFTKASVLTSDIIRPGDILGLTIWENVDDGLLASAGANATLLEEVQVDGAGFI
CCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCEECCCCCCEEEEEEEECCCCEE
FVPYAGRVRASGNTPEQLREAITKKLEDQTPDPQVQVRRLAGDGATVSLTGAVGAQGVYP
EEECCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHEEEEECCCCCEEEEEECCCCCCCCC
IERPTRTLATMLAQAGGVAIEPEIAQVSVTRQGQTGTIWFEDLYDHPQMDIALRNGDKIL
CCCHHHHHHHHHHHCCCEEECCCEEEEEEEECCCCCEEEEHHHCCCCCEEEEEECCCEEE
VEGDTRSFTALGATAAQARVPFESQNLSALEALAQVGGLIATASDPTGVFVFRNEPEAIS
EECCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHCCEEEECCCCCEEEEECCCCHHHH
NQVLGRDDLIGAQRMIYVLNLTQPNGLFIARDFVIRDGDTIYVTEAPYAQWTKTLSLLTS
HHHCCCHHCCCCEEEEEEEEECCCCCEEEEEEEEEECCCEEEEECCCHHHHHHHHHHHHH
PLSTAASVETLFGGS
CHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1659649; 1371768; 10710307 [H]