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The map label for this gene is csd [H]

Identifier: 99081943

GI number: 99081943

Start: 2208354

End: 2209778

Strand: Reverse

Name: csd [H]

Synonym: TM1040_2103

Alternate gene names: 99081943

Gene position: 2209778-2208354 (Counterclockwise)

Preceding gene: 99081945

Following gene: 99081942

Centisome position: 69.04

GC content: 63.86

Gene sequence:

>1425_bases
ATGATCTTTGATGAGTTCAAAACGTCGATCAAAAACACAGCGGACGCGGGGCAACTGGCCGCGACATTGATTGGCGAAGG
GGTCATGATCCCCGGCCTCAGAGGTGATGTGCCGCTGGTCTATGCAGACTATGTGGCCTCTGGGCGCGCGATGCGCCCAG
TCGAAGACTTCATTGCCGAAAAGCTCCTGCCGTTTTATGCCAACTCGCACACCGAAGCGTCCTATTGCGGGCAGTATGTG
ACCCGGATGCGGCGTGAGGCGCGGGCAGAAATCGCGCGGCTGACGGGTGCGGGGGACGACTGCGAGGTGATCTTTGCAGG
CTCCGGTGCCACGGCGGGTTTGAACCGGTTGGTGAAGCTTTTGGGGATTGAAGAGGCCACGCGCCCGGTTGTGTTTATCG
GCCCCTATGAGCATCACTCCAACATCCTGCCGTGGCGCGAGAGCCGCGCCGAGGTGGTCGAAATCCCCGAAGGCCCTGAT
GGCGGCGTGGATCTCGCAGCCCTCGAGGCGGCCTTGGTTGCGCATGCGGAGGCGGATCTGAAGATCGGCAGCTTCTCGGC
GGCGTCGAACGTGACGGGGATCATCACCGATCCCGACCCGGTCACGCGGCTGTTGCGCGCGCATGGCGCACTTGCGGTTT
GGGACTATGCCGGGGGTGGGCCCTATCTGCCCATCGACATGGGCGCGCATGGCGCCGAGCCTAAGGACGCTGTTGTGGTT
TCGCCGCACAAATTTCCGGGCGGGCCGGGGGCCTCTGGCGTTCTGGTGCTGCGCCGCGATGCGGTGCGGGCGCAAAACCC
CTCATGGCCAGGGGGGGGCACGGTGAGCTTTGTCTCGCCTTGGTCGCATCGCTACGCTGACAGTCTCAGCGCGCGAGAGG
AAGCCGGCACGCCCAATGTGGTGGGTGACATTCGTGCGGCGCTGGCGTTTTTGGTCAAGGAAGCCGTGGGGCAGGAGCAG
ATCGAGGCCCGCGAGGCGCAGTACGCTGCAAAGGCGCGCGCGGCCTGGGCGGATGTGCCGGGGCTGACGCTTCTGGGGCA
CGCGCATGCCCACCGGCTGCCGATCTTTTCCTTTACCGTGGAAGGGGCCTCCGGTGCGCCGGTGCATCAGCAACTCTTCA
CCCGCATGCTCAGCGATGTTTATGGCATTCAGGCGCGTGGTGGATGCGCCTGCGCGGGACCTTATGCACACCGGCTGCTT
GAGATCGACGAGCCTCAGTCTGAGGCCCTGCTTAGGGATCTTCTTGCCGGACGGGAGCTGCAGAAACCGGGCTGGGTGCG
GTTGAACTTCTCTTACCTGATGGCCGAAGAGACCGTGGATTATGTGATCGAGAGCGTGAAGGCGCTGGTGCTGGAGGCCG
AAAATGTCGCCTCTGCTTATGATGCGGATCCGAGCACCGCGCGCTTTCAGCCACGGGCAGCCTGA

Upstream 100 bases:

>100_bases
ATCATATGAAATGGATATACCGCTGTCACCCGTGAACTTAGGTGAAAATGAACGCTCATAGGTGGTCTATCATTGCAGAA
ATAGCAATGAGGGCGCGCAT

Downstream 100 bases:

>100_bases
CGAATACCCTGTCTTTGATGCCGGGAAGAGATTCTAGGCACAGGATGTTTCGCCTCGGGCTTTGCCCGAGGCGACCCGCG
TCGCGCGCCCTCAGGGCGCG

Product: aminotransferase, class V

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MIFDEFKTSIKNTADAGQLAATLIGEGVMIPGLRGDVPLVYADYVASGRAMRPVEDFIAEKLLPFYANSHTEASYCGQYV
TRMRREARAEIARLTGAGDDCEVIFAGSGATAGLNRLVKLLGIEEATRPVVFIGPYEHHSNILPWRESRAEVVEIPEGPD
GGVDLAALEAALVAHAEADLKIGSFSAASNVTGIITDPDPVTRLLRAHGALAVWDYAGGGPYLPIDMGAHGAEPKDAVVV
SPHKFPGGPGASGVLVLRRDAVRAQNPSWPGGGTVSFVSPWSHRYADSLSAREEAGTPNVVGDIRAALAFLVKEAVGQEQ
IEAREAQYAAKARAAWADVPGLTLLGHAHAHRLPIFSFTVEGASGAPVHQQLFTRMLSDVYGIQARGGCACAGPYAHRLL
EIDEPQSEALLRDLLAGRELQKPGWVRLNFSYLMAEETVDYVIESVKALVLEAENVASAYDADPSTARFQPRAA

Sequences:

>Translated_474_residues
MIFDEFKTSIKNTADAGQLAATLIGEGVMIPGLRGDVPLVYADYVASGRAMRPVEDFIAEKLLPFYANSHTEASYCGQYV
TRMRREARAEIARLTGAGDDCEVIFAGSGATAGLNRLVKLLGIEEATRPVVFIGPYEHHSNILPWRESRAEVVEIPEGPD
GGVDLAALEAALVAHAEADLKIGSFSAASNVTGIITDPDPVTRLLRAHGALAVWDYAGGGPYLPIDMGAHGAEPKDAVVV
SPHKFPGGPGASGVLVLRRDAVRAQNPSWPGGGTVSFVSPWSHRYADSLSAREEAGTPNVVGDIRAALAFLVKEAVGQEQ
IEAREAQYAAKARAAWADVPGLTLLGHAHAHRLPIFSFTVEGASGAPVHQQLFTRMLSDVYGIQARGGCACAGPYAHRLL
EIDEPQSEALLRDLLAGRELQKPGWVRLNFSYLMAEETVDYVIESVKALVLEAENVASAYDADPSTARFQPRAA
>Mature_474_residues
MIFDEFKTSIKNTADAGQLAATLIGEGVMIPGLRGDVPLVYADYVASGRAMRPVEDFIAEKLLPFYANSHTEASYCGQYV
TRMRREARAEIARLTGAGDDCEVIFAGSGATAGLNRLVKLLGIEEATRPVVFIGPYEHHSNILPWRESRAEVVEIPEGPD
GGVDLAALEAALVAHAEADLKIGSFSAASNVTGIITDPDPVTRLLRAHGALAVWDYAGGGPYLPIDMGAHGAEPKDAVVV
SPHKFPGGPGASGVLVLRRDAVRAQNPSWPGGGTVSFVSPWSHRYADSLSAREEAGTPNVVGDIRAALAFLVKEAVGQEQ
IEAREAQYAAKARAAWADVPGLTLLGHAHAHRLPIFSFTVEGASGAPVHQQLFTRMLSDVYGIQARGGCACAGPYAHRLL
EIDEPQSEALLRDLLAGRELQKPGWVRLNFSYLMAEETVDYVIESVKALVLEAENVASAYDADPSTARFQPRAA

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=364, Percent_Identity=28.8461538461538, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789175, Length=371, Percent_Identity=27.4932614555256, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193211090, Length=469, Percent_Identity=35.181236673774, Blast_Score=298, Evalue=4e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 50569; Mature: 50569

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDEFKTSIKNTADAGQLAATLIGEGVMIPGLRGDVPLVYADYVASGRAMRPVEDFIAE
CCHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCEEEEHHHHCCCCCCHHHHHHHH
KLLPFYANSHTEASYCGQYVTRMRREARAEIARLTGAGDDCEVIFAGSGATAGLNRLVKL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
LGIEEATRPVVFIGPYEHHSNILPWRESRAEVVEIPEGPDGGVDLAALEAALVAHAEADL
HCCHHHCCCEEEECCCHHCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCC
KIGSFSAASNVTGIITDPDPVTRLLRAHGALAVWDYAGGGPYLPIDMGAHGAEPKDAVVV
EECCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEE
SPHKFPGGPGASGVLVLRRDAVRAQNPSWPGGGTVSFVSPWSHRYADSLSAREEAGTPNV
CCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCH
VGDIRAALAFLVKEAVGQEQIEAREAQYAAKARAAWADVPGLTLLGHAHAHRLPIFSFTV
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCEEEEEE
EGASGAPVHQQLFTRMLSDVYGIQARGGCACAGPYAHRLLEIDEPQSEALLRDLLAGREL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHEECCCCHHHHHHHHHHCCCCC
QKPGWVRLNFSYLMAEETVDYVIESVKALVLEAENVASAYDADPSTARFQPRAA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIFDEFKTSIKNTADAGQLAATLIGEGVMIPGLRGDVPLVYADYVASGRAMRPVEDFIAE
CCHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCEEEEHHHHCCCCCCHHHHHHHH
KLLPFYANSHTEASYCGQYVTRMRREARAEIARLTGAGDDCEVIFAGSGATAGLNRLVKL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHH
LGIEEATRPVVFIGPYEHHSNILPWRESRAEVVEIPEGPDGGVDLAALEAALVAHAEADL
HCCHHHCCCEEEECCCHHCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCC
KIGSFSAASNVTGIITDPDPVTRLLRAHGALAVWDYAGGGPYLPIDMGAHGAEPKDAVVV
EECCCCCCCCCEEEEECCHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEE
SPHKFPGGPGASGVLVLRRDAVRAQNPSWPGGGTVSFVSPWSHRYADSLSAREEAGTPNV
CCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCH
VGDIRAALAFLVKEAVGQEQIEAREAQYAAKARAAWADVPGLTLLGHAHAHRLPIFSFTV
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCEEEEEE
EGASGAPVHQQLFTRMLSDVYGIQARGGCACAGPYAHRLLEIDEPQSEALLRDLLAGREL
CCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHEECCCCHHHHHHHHHHCCCCC
QKPGWVRLNFSYLMAEETVDYVIESVKALVLEAENVASAYDADPSTARFQPRAA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]