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The map label for this gene is ywbI [H]

Identifier: 99081910

GI number: 99081910

Start: 2174017

End: 2175000

Strand: Direct

Name: ywbI [H]

Synonym: TM1040_2070

Alternate gene names: 99081910

Gene position: 2174017-2175000 (Clockwise)

Preceding gene: 99081903

Following gene: 99081911

Centisome position: 67.92

GC content: 61.99

Gene sequence:

>984_bases
ATGACACCACCAGATCAGGTCCATCCCCGCCCCCATATCGACCCGGAACGTCTGACCCGCGAGATGAACTGGAACCTCCT
GCGCACCTTTGTAGTGCTGGCCGAGAGTGGCTCCATCACCGAGGCAGCAGAGCGTTTGCGCCTGAAACAGCCCTCGGTTT
CGGTTGCGCTCAAGAAGCTTGAAGACCAGCTAGGGCAGCACCTGATAGATCGCTCGCCGGGGCATTTCACCCTCACCAAG
GCCGGCCAGATGCTCTACCGCGAGGCGGTCAACATCAACGGCTCCATCCTGCGGCTGGCGACCCTGATGCGCACCGTCAC
CCCTGAAATCAGTGGCCATGTGCGAATCGCGGTGGCGAGCCATGTGCTCTGCCCGCTGTTTGACAGTGTGATCGGCGATT
TTTACGCCGCGCACCCAAAGGCCAGCCTTGCGATTGACGTGATCACCAGTGGCGATGCGATCACCGCCGTGGCGGCCAAG
CGTGTGAGCTTTGCCCTCGCCCTTGTGCGCGAACAGGACCCAAACCTGCGCTATCTGCCTGTCTACCGCGAAACCTTCGG
ATTGTTCTGTGGCCCCCGTCACCCGCTCTTTGGCCGCAGCGATCTGACCCTTGAGGACCTGAAGGGCCATGCGGCGGTGG
TGTTTGACAATGACCGCCTGCAGGACGCGCTGCAGGATGTCACCCTCTTACGGGCCCGCGCCGCCCTCGCACCCGAGATC
ACGGGCGTTTCTGAAAACCTCGAGGAGGTCCGCCGTATGATCATGGCAGGGCTTGGCATTGGGCCTTTGCCCAAACATGT
GGTCGCGCGCGACATCGAGGATGGTCTGTTGTGGCAGGTCCCTCCGTTCGAGGACCTGCCCGAAGTCGACGTCTATCTGA
TCTGGAACCCGACAACCGTGCGCAACCGCGCCGAGGAAACGCTGCTCACCACTCTGATCGAGCGCCTCGAAACCGTCCCC
TTTGCCGAGCGTTCCTATGCCTGA

Upstream 100 bases:

>100_bases
TACCCCTGCATAGATTCTGATAATGGTCCTGAATATACGTCATCTGGCAGCTCACACTCAGGGCCGACAGACCCACTCTC
AAACCCTTGATTTTAAAAAC

Downstream 100 bases:

>100_bases
CCTCTCAGTTTTCACTTTTTCATAAAGACCTCATTTCAACATATCAGAGCGGCGCAACCTGTGGTCAGGACACAGCACCC
TTGCGCCATCCCCCACTCGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MTPPDQVHPRPHIDPERLTREMNWNLLRTFVVLAESGSITEAAERLRLKQPSVSVALKKLEDQLGQHLIDRSPGHFTLTK
AGQMLYREAVNINGSILRLATLMRTVTPEISGHVRIAVASHVLCPLFDSVIGDFYAAHPKASLAIDVITSGDAITAVAAK
RVSFALALVREQDPNLRYLPVYRETFGLFCGPRHPLFGRSDLTLEDLKGHAAVVFDNDRLQDALQDVTLLRARAALAPEI
TGVSENLEEVRRMIMAGLGIGPLPKHVVARDIEDGLLWQVPPFEDLPEVDVYLIWNPTTVRNRAEETLLTTLIERLETVP
FAERSYA

Sequences:

>Translated_327_residues
MTPPDQVHPRPHIDPERLTREMNWNLLRTFVVLAESGSITEAAERLRLKQPSVSVALKKLEDQLGQHLIDRSPGHFTLTK
AGQMLYREAVNINGSILRLATLMRTVTPEISGHVRIAVASHVLCPLFDSVIGDFYAAHPKASLAIDVITSGDAITAVAAK
RVSFALALVREQDPNLRYLPVYRETFGLFCGPRHPLFGRSDLTLEDLKGHAAVVFDNDRLQDALQDVTLLRARAALAPEI
TGVSENLEEVRRMIMAGLGIGPLPKHVVARDIEDGLLWQVPPFEDLPEVDVYLIWNPTTVRNRAEETLLTTLIERLETVP
FAERSYA
>Mature_326_residues
TPPDQVHPRPHIDPERLTREMNWNLLRTFVVLAESGSITEAAERLRLKQPSVSVALKKLEDQLGQHLIDRSPGHFTLTKA
GQMLYREAVNINGSILRLATLMRTVTPEISGHVRIAVASHVLCPLFDSVIGDFYAAHPKASLAIDVITSGDAITAVAAKR
VSFALALVREQDPNLRYLPVYRETFGLFCGPRHPLFGRSDLTLEDLKGHAAVVFDNDRLQDALQDVTLLRARAALAPEIT
GVSENLEEVRRMIMAGLGIGPLPKHVVARDIEDGLLWQVPPFEDLPEVDVYLIWNPTTVRNRAEETLLTTLIERLETVPF
AERSYA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=301, Percent_Identity=26.2458471760797, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=24.8979591836735, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788481, Length=256, Percent_Identity=26.953125, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790399, Length=289, Percent_Identity=25.6055363321799, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787601, Length=300, Percent_Identity=23, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI157672245, Length=245, Percent_Identity=24.8979591836735, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787530, Length=251, Percent_Identity=26.6932270916335, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=26.2096774193548, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787879, Length=279, Percent_Identity=24.7311827956989, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36423; Mature: 36292

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPDQVHPRPHIDPERLTREMNWNLLRTFVVLAESGSITEAAERLRLKQPSVSVALKKL
CCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHH
EDQLGQHLIDRSPGHFTLTKAGQMLYREAVNINGSILRLATLMRTVTPEISGHVRIAVAS
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHH
HVLCPLFDSVIGDFYAAHPKASLAIDVITSGDAITAVAAKRVSFALALVREQDPNLRYLP
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
VYRETFGLFCGPRHPLFGRSDLTLEDLKGHAAVVFDNDRLQDALQDVTLLRARAALAPEI
EHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
TGVSENLEEVRRMIMAGLGIGPLPKHVVARDIEDGLLWQVPPFEDLPEVDVYLIWNPTTV
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEECCCCCCCCCCCEEEEEECCHHH
RNRAEETLLTTLIERLETVPFAERSYA
HHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TPPDQVHPRPHIDPERLTREMNWNLLRTFVVLAESGSITEAAERLRLKQPSVSVALKKL
CCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHH
EDQLGQHLIDRSPGHFTLTKAGQMLYREAVNINGSILRLATLMRTVTPEISGHVRIAVAS
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEHHH
HVLCPLFDSVIGDFYAAHPKASLAIDVITSGDAITAVAAKRVSFALALVREQDPNLRYLP
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEE
VYRETFGLFCGPRHPLFGRSDLTLEDLKGHAAVVFDNDRLQDALQDVTLLRARAALAPEI
EHHHHHHHHCCCCCCCCCCCCCCHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCC
TGVSENLEEVRRMIMAGLGIGPLPKHVVARDIEDGLLWQVPPFEDLPEVDVYLIWNPTTV
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEECCCCCCCCCCCEEEEEECCHHH
RNRAEETLLTTLIERLETVPFAERSYA
HHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]