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The map label for this gene is soxA [H]

Identifier: 99081903

GI number: 99081903

Start: 2165626

End: 2168046

Strand: Direct

Name: soxA [H]

Synonym: TM1040_2063

Alternate gene names: 99081903

Gene position: 2165626-2168046 (Clockwise)

Preceding gene: 99081902

Following gene: 99081910

Centisome position: 67.66

GC content: 61.46

Gene sequence:

>2421_bases
ATGCGTACAGAAGCCAAGGCCGTGGTCATCGGCGGCGGGGTCATCGGTTGTTCGATCCTTTATCACCTGACCAAACTCGG
CTGGTCCGATGTGGTGTTGCTGGAGCGCGACGAGCTGACCTCGGGATCGACCTGGCACGCGGCGGCCAATATCCATGGCC
TGCACGACAGCACCAACATCTCGCGCATCCAGCACTATACGATGACGCTCTACAAGGAGCTCGAGCAGGAAACCGGCCAG
GGCTGCGGCGTGTTTCAGCCCGGATCTCTCTATCTGGCGCAGACCGAAGACCGCGCGCACCAGCTGCGTCTGCAGGCCGC
CAAGGCCAAGCTCTACGGGATGAACTTCTACGAGATTTCCATCGAGGAAGCTCAGGAACTCAACCCGCTGGTGAATTTCG
ACGGGATCCGCTGTGTCATGTATGAGCCCGATGGCGGCAATGTGGACCCCTCCGGTGTGACACAAGCCTACGCCACCGGC
GCGCGGCAACGCGGCGCCGAGATCCATCGTTTCACGCCGGTCACGGCCACAGAGGCGCAGCCTGATGGCACCTGGATTGT
AAAAACCCCCAAGGGCGACATTCACACCGACTGGGTGGTGAATGCAGCGGGTCTTTGGGGCCGGGAGGTGGCAAAACTTG
CGGGCCTCGAGTTGCCTCTGCAACCCACCGAGCATCAGTATTTTGTCACCGAAACGATTCCGGAGATCGCCGGAATGGAG
CGTCGCCTGCCATCTGTATCGGATCGCGACGGGGAATATTACCTGCGCCAAGAGGGACAGGGGCTTCTGGTGGGTGCCTA
TGAGAAGGGCATGAAATTCTGGGCCGAGGACGGCACGCCCCTGGATTTTGCGCATGACCTGTTCCCCGACGACCTCGAGC
GCATCGAAGAAAACATGATGAACGCCATCGAACGTGTGCCTGTGGTGGGGGATGCGGGCATCAAGCGCGTGATCAACGGA
CCAATGATCTGGTCACCCGATGCCAATGTGTTGTTTGGCCCGGTGCCGGAGCTTTCGGGCTATTTCTGCTGCAATGGCAT
CATCCCCGGCTTTTCGCAGTCCGGCGGTATGGGCCTGATGGCGGCGCAGTGGATGATCGAGGGCGAGACGCAGTTTGACA
TGTTCAACTGGGACGTGGCGCGGTTTGGCGACTGGGCCACAAAGGAATTCACCAAGGCGCGCGTAGAGGATCAATATGCG
CATCGGTTTGCGATCCATTTCCCAAATGAAGAGCGCAGCGCAGGCCGCCCCGCCCGCACCCGCCCGATCTATGAGATGCA
GCGCGAGATGGGCGCGGTCTTTGGGCTCAATGCCGGATGGGAGCACCCCTTGTGGTTTGCGGATCAGCCCGGCGCCGAGG
ACACCAATGGCTTTACCCGGCAGAACTGGTGGGGGCCGGTGGGCGAAGAATGCAAGATGCTGCGCGCGCGTGCCGGCATC
ATCGACATATCGAATTTCGCCAAATACCGCTGCAAAGGCCCTGATGCCGAGGACTGGCTGAATGCGGTATTTGCCAATCG
CATGCCAAAGGCGGTGGGGCGGTCGTGCCTCACGCCCTTGATTTCAAAGCGCGGCGGGATCGCCGGGGATTTCACCGTCA
CACGGCTGGCGGAGGATGAATTCTGGGTCATCGGCTCCGGCATGGCGGAGCGCTATCACAAGCGGTTCTTTGGTGCGGTG
CCCTTGCCGGAAGGGACCTCGTTTGAGAGCCTCACCCAGGAGGTCTGCGGTTTCAACGTGGCAGGCCCCAAGTCGCGCGA
GATGCTCCAGCGCATGACCAATGAGCCTTTGGACACCGCCTCATTCCCCTTCATGCGCAGCAAACGACTGATGCTCGCAG
GGATCAATGTTGTGGCGTTGCGCGTCTCTTTCACGGGGGACCTCGGCTGGGAGTTGCACTGCGCCACAGAGGATCAGGAA
AAGCTTTATATCGCGTTGATCGAAGCAGGCCGAGAGTTCGGCGCCGGCCCCGTGGGCAGTCGCGCCCTGATGTCGCTGCG
CGTCGAGAAGGGCTATGGCTCCTGGAGCCGCGAGTACAGCCCCGAGTACTTCCCGCATGAGGTGGGATTTCAGCCGCTGT
GTAAAATGGACAAGGATTTCCTCAACAAATCTGCCGCCGAGACCGCGATGGGCACGCCTGCGCGCGAGGAATTGGTGCTG
CTGCATCTCACTGCCGAGGATGTGGAGGCCTCTGACGCCGATGCCACCGGGGGGGAGCCGATTTTCAAGGACGGACGCGG
TATCGGGCGGGTAACATCGGGCACCTATGGATACACGGTCGGCATGTCTCTGGCTCTTGGCTATGTCAAAGACGCCAAGC
CCGGTGATACCGTCGAGGTGATGGTGCTGGGGCGCGCGCACCGTGCCGTGATCCTCGCCGAGCCGCCCTTTGACCCCAAG
GGCGAGCGGCTGCGCGCCTAG

Upstream 100 bases:

>100_bases
TCATGCGAGCATGAGAATTATCGAGGTTGCCCAAGGTGGGGCGGCGGTGGAACATTTCCCCAACGCCCCTTCCCCGCAGC
AAAGCAAAGGCACCCTCATC

Downstream 100 bases:

>100_bases
GACAAAACAGCCGGTCGGTTCTGCGGCAGGAGCGCCGCGATACCGGCGCTGTCACCGCCGTCGATGAGCGCGCCAAGGTG
ACGTGCGGTGGTGGGGCCAA

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: Sarcosine oxidase subunit [H]

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MRTEAKAVVIGGGVIGCSILYHLTKLGWSDVVLLERDELTSGSTWHAAANIHGLHDSTNISRIQHYTMTLYKELEQETGQ
GCGVFQPGSLYLAQTEDRAHQLRLQAAKAKLYGMNFYEISIEEAQELNPLVNFDGIRCVMYEPDGGNVDPSGVTQAYATG
ARQRGAEIHRFTPVTATEAQPDGTWIVKTPKGDIHTDWVVNAAGLWGREVAKLAGLELPLQPTEHQYFVTETIPEIAGME
RRLPSVSDRDGEYYLRQEGQGLLVGAYEKGMKFWAEDGTPLDFAHDLFPDDLERIEENMMNAIERVPVVGDAGIKRVING
PMIWSPDANVLFGPVPELSGYFCCNGIIPGFSQSGGMGLMAAQWMIEGETQFDMFNWDVARFGDWATKEFTKARVEDQYA
HRFAIHFPNEERSAGRPARTRPIYEMQREMGAVFGLNAGWEHPLWFADQPGAEDTNGFTRQNWWGPVGEECKMLRARAGI
IDISNFAKYRCKGPDAEDWLNAVFANRMPKAVGRSCLTPLISKRGGIAGDFTVTRLAEDEFWVIGSGMAERYHKRFFGAV
PLPEGTSFESLTQEVCGFNVAGPKSREMLQRMTNEPLDTASFPFMRSKRLMLAGINVVALRVSFTGDLGWELHCATEDQE
KLYIALIEAGREFGAGPVGSRALMSLRVEKGYGSWSREYSPEYFPHEVGFQPLCKMDKDFLNKSAAETAMGTPAREELVL
LHLTAEDVEASDADATGGEPIFKDGRGIGRVTSGTYGYTVGMSLALGYVKDAKPGDTVEVMVLGRAHRAVILAEPPFDPK
GERLRA

Sequences:

>Translated_806_residues
MRTEAKAVVIGGGVIGCSILYHLTKLGWSDVVLLERDELTSGSTWHAAANIHGLHDSTNISRIQHYTMTLYKELEQETGQ
GCGVFQPGSLYLAQTEDRAHQLRLQAAKAKLYGMNFYEISIEEAQELNPLVNFDGIRCVMYEPDGGNVDPSGVTQAYATG
ARQRGAEIHRFTPVTATEAQPDGTWIVKTPKGDIHTDWVVNAAGLWGREVAKLAGLELPLQPTEHQYFVTETIPEIAGME
RRLPSVSDRDGEYYLRQEGQGLLVGAYEKGMKFWAEDGTPLDFAHDLFPDDLERIEENMMNAIERVPVVGDAGIKRVING
PMIWSPDANVLFGPVPELSGYFCCNGIIPGFSQSGGMGLMAAQWMIEGETQFDMFNWDVARFGDWATKEFTKARVEDQYA
HRFAIHFPNEERSAGRPARTRPIYEMQREMGAVFGLNAGWEHPLWFADQPGAEDTNGFTRQNWWGPVGEECKMLRARAGI
IDISNFAKYRCKGPDAEDWLNAVFANRMPKAVGRSCLTPLISKRGGIAGDFTVTRLAEDEFWVIGSGMAERYHKRFFGAV
PLPEGTSFESLTQEVCGFNVAGPKSREMLQRMTNEPLDTASFPFMRSKRLMLAGINVVALRVSFTGDLGWELHCATEDQE
KLYIALIEAGREFGAGPVGSRALMSLRVEKGYGSWSREYSPEYFPHEVGFQPLCKMDKDFLNKSAAETAMGTPAREELVL
LHLTAEDVEASDADATGGEPIFKDGRGIGRVTSGTYGYTVGMSLALGYVKDAKPGDTVEVMVLGRAHRAVILAEPPFDPK
GERLRA
>Mature_806_residues
MRTEAKAVVIGGGVIGCSILYHLTKLGWSDVVLLERDELTSGSTWHAAANIHGLHDSTNISRIQHYTMTLYKELEQETGQ
GCGVFQPGSLYLAQTEDRAHQLRLQAAKAKLYGMNFYEISIEEAQELNPLVNFDGIRCVMYEPDGGNVDPSGVTQAYATG
ARQRGAEIHRFTPVTATEAQPDGTWIVKTPKGDIHTDWVVNAAGLWGREVAKLAGLELPLQPTEHQYFVTETIPEIAGME
RRLPSVSDRDGEYYLRQEGQGLLVGAYEKGMKFWAEDGTPLDFAHDLFPDDLERIEENMMNAIERVPVVGDAGIKRVING
PMIWSPDANVLFGPVPELSGYFCCNGIIPGFSQSGGMGLMAAQWMIEGETQFDMFNWDVARFGDWATKEFTKARVEDQYA
HRFAIHFPNEERSAGRPARTRPIYEMQREMGAVFGLNAGWEHPLWFADQPGAEDTNGFTRQNWWGPVGEECKMLRARAGI
IDISNFAKYRCKGPDAEDWLNAVFANRMPKAVGRSCLTPLISKRGGIAGDFTVTRLAEDEFWVIGSGMAERYHKRFFGAV
PLPEGTSFESLTQEVCGFNVAGPKSREMLQRMTNEPLDTASFPFMRSKRLMLAGINVVALRVSFTGDLGWELHCATEDQE
KLYIALIEAGREFGAGPVGSRALMSLRVEKGYGSWSREYSPEYFPHEVGFQPLCKMDKDFLNKSAAETAMGTPAREELVL
LHLTAEDVEASDADATGGEPIFKDGRGIGRVTSGTYGYTVGMSLALGYVKDAKPGDTVEVMVLGRAHRAVILAEPPFDPK
GERLRA

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=808, Percent_Identity=38.8613861386139, Blast_Score=577, Evalue=1e-164,
Organism=Homo sapiens, GI197927446, Length=866, Percent_Identity=32.7944572748268, Blast_Score=414, Evalue=1e-115,
Organism=Homo sapiens, GI21361378, Length=866, Percent_Identity=32.7944572748268, Blast_Score=414, Evalue=1e-115,
Organism=Homo sapiens, GI194306651, Length=785, Percent_Identity=28.1528662420382, Blast_Score=320, Evalue=3e-87,
Organism=Escherichia coli, GI1789272, Length=397, Percent_Identity=23.9294710327456, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32563613, Length=814, Percent_Identity=27.5184275184275, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71994045, Length=825, Percent_Identity=27.3939393939394, Blast_Score=275, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI71994052, Length=832, Percent_Identity=27.1634615384615, Blast_Score=272, Evalue=5e-73,
Organism=Drosophila melanogaster, GI20130091, Length=864, Percent_Identity=29.6296296296296, Blast_Score=341, Evalue=1e-93,
Organism=Drosophila melanogaster, GI28571104, Length=795, Percent_Identity=30.314465408805, Blast_Score=320, Evalue=2e-87,
Organism=Drosophila melanogaster, GI20129441, Length=397, Percent_Identity=26.9521410579345, Blast_Score=83, Evalue=9e-16,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006277 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C; PF07992 Pyr_redox_2 [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 89271; Mature: 89271

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTEAKAVVIGGGVIGCSILYHLTKLGWSDVVLLERDELTSGSTWHAAANIHGLHDSTNI
CCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCH
SRIQHYTMTLYKELEQETGQGCGVFQPGSLYLAQTEDRAHQLRLQAAKAKLYGMNFYEIS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHEECCEEEEEE
IEEAQELNPLVNFDGIRCVMYEPDGGNVDPSGVTQAYATGARQRGAEIHRFTPVTATEAQ
HHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCC
PDGTWIVKTPKGDIHTDWVVNAAGLWGREVAKLAGLELPLQPTEHQYFVTETIPEIAGME
CCCCEEEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHCHH
RRLPSVSDRDGEYYLRQEGQGLLVGAYEKGMKFWAEDGTPLDFAHDLFPDDLERIEENMM
HCCCCCCCCCCCEEEEECCCEEEEEEHHHCCCEECCCCCCCCHHHHCCHHHHHHHHHHHH
NAIERVPVVGDAGIKRVINGPMIWSPDANVLFGPVPELSGYFCCNGIIPGFSQSGGMGLM
HHHHHCCCCCCCHHHHHHCCCEEECCCCCEEECCCCCCCCEEEECCCCCCCCCCCCCEEE
AAQWMIEGETQFDMFNWDVARFGDWATKEFTKARVEDQYAHRFAIHFPNEERSAGRPART
EEEEEECCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCC
RPIYEMQREMGAVFGLNAGWEHPLWFADQPGAEDTNGFTRQNWWGPVGEECKMLRARAGI
CCHHHHHHHHHHEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCE
IDISNFAKYRCKGPDAEDWLNAVFANRMPKAVGRSCLTPLISKRGGIAGDFTVTRLAEDE
EECCCCHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
FWVIGSGMAERYHKRFFGAVPLPEGTSFESLTQEVCGFNVAGPKSREMLQRMTNEPLDTA
EEEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
SFPFMRSKRLMLAGINVVALRVSFTGDLGWELHCATEDQEKLYIALIEAGREFGAGPVGS
CCCHHHCCEEEEECCEEEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCHHHCCCCCCC
RALMSLRVEKGYGSWSREYSPEYFPHEVGFQPLCKMDKDFLNKSAAETAMGTPAREELVL
HHEEEEEEECCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LHLTAEDVEASDADATGGEPIFKDGRGIGRVTSGTYGYTVGMSLALGYVKDAKPGDTVEV
EEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEE
MVLGRAHRAVILAEPPFDPKGERLRA
EEEECCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRTEAKAVVIGGGVIGCSILYHLTKLGWSDVVLLERDELTSGSTWHAAANIHGLHDSTNI
CCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEECCCCCCCH
SRIQHYTMTLYKELEQETGQGCGVFQPGSLYLAQTEDRAHQLRLQAAKAKLYGMNFYEIS
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHEECCEEEEEE
IEEAQELNPLVNFDGIRCVMYEPDGGNVDPSGVTQAYATGARQRGAEIHRFTPVTATEAQ
HHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEECCCC
PDGTWIVKTPKGDIHTDWVVNAAGLWGREVAKLAGLELPLQPTEHQYFVTETIPEIAGME
CCCCEEEECCCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCEEEHHHHHHHHCHH
RRLPSVSDRDGEYYLRQEGQGLLVGAYEKGMKFWAEDGTPLDFAHDLFPDDLERIEENMM
HCCCCCCCCCCCEEEEECCCEEEEEEHHHCCCEECCCCCCCCHHHHCCHHHHHHHHHHHH
NAIERVPVVGDAGIKRVINGPMIWSPDANVLFGPVPELSGYFCCNGIIPGFSQSGGMGLM
HHHHHCCCCCCCHHHHHHCCCEEECCCCCEEECCCCCCCCEEEECCCCCCCCCCCCCEEE
AAQWMIEGETQFDMFNWDVARFGDWATKEFTKARVEDQYAHRFAIHFPNEERSAGRPART
EEEEEECCCCEEEEECCCHHHCCCHHHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCC
RPIYEMQREMGAVFGLNAGWEHPLWFADQPGAEDTNGFTRQNWWGPVGEECKMLRARAGI
CCHHHHHHHHHHEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCE
IDISNFAKYRCKGPDAEDWLNAVFANRMPKAVGRSCLTPLISKRGGIAGDFTVTRLAEDE
EECCCCHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
FWVIGSGMAERYHKRFFGAVPLPEGTSFESLTQEVCGFNVAGPKSREMLQRMTNEPLDTA
EEEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCC
SFPFMRSKRLMLAGINVVALRVSFTGDLGWELHCATEDQEKLYIALIEAGREFGAGPVGS
CCCHHHCCEEEEECCEEEEEEEEECCCCCEEEEECCCCCCEEEEEEEECCHHHCCCCCCC
RALMSLRVEKGYGSWSREYSPEYFPHEVGFQPLCKMDKDFLNKSAAETAMGTPAREELVL
HHEEEEEEECCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
LHLTAEDVEASDADATGGEPIFKDGRGIGRVTSGTYGYTVGMSLALGYVKDAKPGDTVEV
EEEECCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCCEEEE
MVLGRAHRAVILAEPPFDPKGERLRA
EEEECCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]