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The map label for this gene is trkH [H]

Identifier: 99081776

GI number: 99081776

Start: 2037616

End: 2039064

Strand: Reverse

Name: trkH [H]

Synonym: TM1040_1935

Alternate gene names: 99081776

Gene position: 2039064-2037616 (Counterclockwise)

Preceding gene: 99081777

Following gene: 99081775

Centisome position: 63.7

GC content: 58.8

Gene sequence:

>1449_bases
ATGTTGGATCTGCGCCCCGTCGGATATGTCATTGGCCTGCTCGTCGTCATTTTGGGCGGCACCATGGTTTTCCCACTCCT
CCTTGATCTTTACGATGGCAAGGGGGAGTGGCCTGTGTTTCTCGAAAGCGCCCTCTTCTGTTTTCTGGTCGGAGGGGTTT
TGGCCTTGACCTGCGCCAATGGGGTAGGGCGGGGATTGTCGATCCGCCAGACCTTTTTGCTCACCACATTGGTCTGGGTG
GTGCTGCCGATTTTTGGCGCGTTGCCCTTGATGCTGGGGGCAACCGAACTGAGTTTCACGGATGCTTTTTTTGAGGCGAT
GTCGGGGCTGACGACCACCGGGTCAACGGTGATCTCGGGGCTTGATGATCTGCCGCGTGGTCTGTTGCTGTGGCGGGGCA
TCCTGCAATGGCTGGGTGGCATTGGTATCATTGTGGTCGCCATGGTGTTCCTGCCGGAGCTCCGGGTTGGGGGCATGCAG
ATCTTTAAATCCGAAGCCTTTGACACGATGGGGAAAATCCTCCCGCGTGCACAGGAAATCGCCAAGCAGATCTCGGTGAT
CTACCTGGTGCTCACATTGGTCTGTGCGCTGGTTTACACGGTTCTGGGTATGGGGCTTTTTGATGCGGTGGTGCATGCGA
TGACCACCATGTCGACGGGCGGGTTCTCCAATTACGACGCGTCTTTTGGCACGTTTTCCGGTCCGGCGGAGTATGCCGCC
GCCATCTTTATGGTGGTCGCGGCTCTGCCGTTTGTGCGCTATGTGCAGATGGTCAACGGCAAGACCCTGCCGCTGTTTCA
GGACTCGCAGGTGCGGGCCTTCATGGCGACGATCCTTTTGCTTGTGGCCATCACCGCCGGGGTGCTTGTGACCATCTTTC
CGCATCATCCCGAGCAGGCCGTGCGCGAGGCCCTGTTCAACATCATCTCCATCATGTCCGGAACCGGTTATGCCAGTGTC
GACTACATGGCCTGGGGGCCGTTCCTGATCATGATCTTCTTCTTTATCGGGCTCATTGGGGGCTGCGCGGGCTCGACCGC
CTGTTCGGTGAAGATCTTCCGCTACCAGCTTCTCTTTGCCTCGATCAGGGTGCAGGTGCAGCGCATCCGCTCGCCCAACG
GGGTCTTTGTGCCGCGCTATGAGGGGCGACCGGTCACGCCCGATGTTCTAAGCTCGGTGATCTCGTTTTTCATGTTCTTC
GTCATCACGCTGGGCATCGTGGCCTGGGCGCTCGCGCTGACGGGGCTCGACTTCATCACCGCCATCTCGGGAGCAGCAAC
AGCGGTTGCCAATATCGGTCCCGGTCTTGGAGATATCATCGGGCCTGCGGGGAACTTCGCCCCGCTCAATGACACCGCCA
AGTGGATTTTGGCCATCGCAATGCTGATCGGGCGACTGGAGCTGATGGCGGTTTATGCGATCCTGACGGTTCGTTTCTGG
CGCAGCTAG

Upstream 100 bases:

>100_bases
CGATGCCTGCGACAGCGGCGCACAACACAGAGGACACAAAGAGCGAGTCGTGATCGCTTTGGCTTGACAGTTCGAGCGGG
GGTTGCCAACGCTGCCCGTC

Downstream 100 bases:

>100_bases
GCCAATCCGGGGCTGAAGGTTGCTCAAAACGCCCTGCGCCTTGAAATAAAGGGCTGGGCCATCTTGCTCTTGCGCGGGCG
CTCGCCTAAGAACGCGCGAA

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 482

Protein sequence:

>482_residues
MLDLRPVGYVIGLLVVILGGTMVFPLLLDLYDGKGEWPVFLESALFCFLVGGVLALTCANGVGRGLSIRQTFLLTTLVWV
VLPIFGALPLMLGATELSFTDAFFEAMSGLTTTGSTVISGLDDLPRGLLLWRGILQWLGGIGIIVVAMVFLPELRVGGMQ
IFKSEAFDTMGKILPRAQEIAKQISVIYLVLTLVCALVYTVLGMGLFDAVVHAMTTMSTGGFSNYDASFGTFSGPAEYAA
AIFMVVAALPFVRYVQMVNGKTLPLFQDSQVRAFMATILLLVAITAGVLVTIFPHHPEQAVREALFNIISIMSGTGYASV
DYMAWGPFLIMIFFFIGLIGGCAGSTACSVKIFRYQLLFASIRVQVQRIRSPNGVFVPRYEGRPVTPDVLSSVISFFMFF
VITLGIVAWALALTGLDFITAISGAATAVANIGPGLGDIIGPAGNFAPLNDTAKWILAIAMLIGRLELMAVYAILTVRFW
RS

Sequences:

>Translated_482_residues
MLDLRPVGYVIGLLVVILGGTMVFPLLLDLYDGKGEWPVFLESALFCFLVGGVLALTCANGVGRGLSIRQTFLLTTLVWV
VLPIFGALPLMLGATELSFTDAFFEAMSGLTTTGSTVISGLDDLPRGLLLWRGILQWLGGIGIIVVAMVFLPELRVGGMQ
IFKSEAFDTMGKILPRAQEIAKQISVIYLVLTLVCALVYTVLGMGLFDAVVHAMTTMSTGGFSNYDASFGTFSGPAEYAA
AIFMVVAALPFVRYVQMVNGKTLPLFQDSQVRAFMATILLLVAITAGVLVTIFPHHPEQAVREALFNIISIMSGTGYASV
DYMAWGPFLIMIFFFIGLIGGCAGSTACSVKIFRYQLLFASIRVQVQRIRSPNGVFVPRYEGRPVTPDVLSSVISFFMFF
VITLGIVAWALALTGLDFITAISGAATAVANIGPGLGDIIGPAGNFAPLNDTAKWILAIAMLIGRLELMAVYAILTVRFW
RS
>Mature_482_residues
MLDLRPVGYVIGLLVVILGGTMVFPLLLDLYDGKGEWPVFLESALFCFLVGGVLALTCANGVGRGLSIRQTFLLTTLVWV
VLPIFGALPLMLGATELSFTDAFFEAMSGLTTTGSTVISGLDDLPRGLLLWRGILQWLGGIGIIVVAMVFLPELRVGGMQ
IFKSEAFDTMGKILPRAQEIAKQISVIYLVLTLVCALVYTVLGMGLFDAVVHAMTTMSTGGFSNYDASFGTFSGPAEYAA
AIFMVVAALPFVRYVQMVNGKTLPLFQDSQVRAFMATILLLVAITAGVLVTIFPHHPEQAVREALFNIISIMSGTGYASV
DYMAWGPFLIMIFFFIGLIGGCAGSTACSVKIFRYQLLFASIRVQVQRIRSPNGVFVPRYEGRPVTPDVLSSVISFFMFF
VITLGIVAWALALTGLDFITAISGAATAVANIGPGLGDIIGPAGNFAPLNDTAKWILAIAMLIGRLELMAVYAILTVRFW
RS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=489, Percent_Identity=35.3783231083845, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1787626, Length=488, Percent_Identity=32.172131147541, Blast_Score=236, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 51847; Mature: 51847

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure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CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]