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The map label for this gene is 99081737

Identifier: 99081737

GI number: 99081737

Start: 1997303

End: 1998976

Strand: Direct

Name: 99081737

Synonym: TM1040_1896

Alternate gene names: NA

Gene position: 1997303-1998976 (Clockwise)

Preceding gene: 99081736

Following gene: 99081738

Centisome position: 62.4

GC content: 65.77

Gene sequence:

>1674_bases
ATGGCCGCCGCACAGCGCGACAACCACGCCGATGTCATCGTGATCGGGGCCGGTCTGGCAGGTCTGGTTGCGGCCAATGA
GCTGGCGGATCGCGGCAAGCGGGTGATCCTGCTGGAACAGGAGCCGGCTCATTTCATCGGCGGGCAAGCCCATTGGAGCC
TTGGCGGCCTCTTTATGGTGGACACCCCCGAGCAGCGCCGCATGGGCATCCGCGACAGTCTGGATCTTGCGCAGCGCGAC
TGGGCGGGCAGCGCGCAGTTCGACCGTCCCGAGGATCAGAGCCCGCGTCAATGGGCCAAGGCCTATCTCGAGTTTGCCGC
AGGCGATATGCGCGCGTGGCTGCATGATCTGGGCCTGCGCTGGTTTCCAGTCGTGGGCTGGGCCGAGCGCGGCGATGGGC
GCGCCGAAGGGCATGGCAACTCCGTGCCGCGGTTCCATATCACATGGGGCACCGGGCCGGGCGTAGTCGCCCCATTTGCC
CAGCGCGTGCATGCCCATGTTGCGACGGGACGGATCGACGCGCGCTTTCGCCATCAGGTCAGCCATATCATCCAGCAGGG
CGGTCACATCAAAGGGGTTTCGGGCGAGGTGCTGGCCGATGACCAGGGCCCGATCGGCGCACAAACCAACCGGCATGAGG
TCGGCGAGTTCGAAGTCTACGCGCCCTCGCTCATTGTGGCCTCGGGGGGGATCGGCGGCAATCTGGAGATGGTCCGCGAA
AACTGGCCGACAGAGCGGCTTGGCCCGGCGCCCAGCCGGATGGTGTCGGGCGTGCCGGCCCATGTGGACGGGCGCATGCT
GAAGGTCGCGCAGGCGGCGGGCGGCCATATCATCAACGGCGACCGCATGTGGCACTATTGCGAGGGGCTGAGAAACTGGG
ACCCGATCTGGCCCAACCACGGCATCCGCATCCTGCCCGGCCCGTCGTCGCTCTGGTTTGACGCACATGGCACCCGCTTG
CCCGATCCGGCGCTGCCGGGGTTTGACACGCTTGGGACGCTCAAGGCAATCTTGGCCAGCGGGCAGGACTACAGCTGGTT
CATCCTCAGTCAGAAGATCATCCAGAAGGAATTTGCACTGTCGGGCTCGGAACAGAACCCAGACCTCACGTCCGGCACAT
GGGCCGAAGTGCTCCGGGCGCGGATCTTTTCCGGCGGCAAGGCCCCCGTCCCGGTCGAAGCCTTCAAGAAACATGGCGCG
GATTTTGTGGTGGCCGAGACGCTCTCGGACCTTGTGCGCGGCATGAATGAGATCGCGGATGTGCCGCTTGACGAGGCACA
TATCCGCGCCCAGATCGAGGCGCGCGATGCGCAGGTCGACAATCCCTTTGCCAAGGACCGCCAGATCCAGGCGATCCACG
CGGCGCGCAATTATCGCGGTGACCGGCTTATTCGCACGGCGAAACCGCATCGGTTGCTGGACCGCGCCAATGGGCCGCTG
ATCGCGGTGCGGCTCAGTATCCTCACCCGCAAGACATTGGGCGGGCTGCACACCACACTGGAGAGTCAGATGATCGGCGC
AGACGGGGCGCCCCTGCCCGGCCTCTTTGCGGTGGGCGAAGCGGCTGGCTTTGGCGGGGGTGGGTATCACGGCTACAATG
CGCTTGAGGGCACGTTTCTGGGGGGCTGCCTCTTTTCGGGGCGTCAGGCTGGGCGTTCGGATCAGATCGCGTGA

Upstream 100 bases:

>100_bases
ATGCGTTGCCCTTGCGGCAGCCCCACACGCAAAGATTGCGCGACTGGCCGCCTTGCGCCTAGGCTCTGGAGGAAAGGCAC
GCCACTGAAGGAGGAGCGCC

Downstream 100 bases:

>100_bases
TCTGGGCGGAAACGTGTGCTAGGCAGCCGCGATGACACCGCCCTCTCCAGATACGATCTATTTTTACGCGCAAACGGACC
CTTATGCGGAGTTTTCAAAC

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MAAAQRDNHADVIVIGAGLAGLVAANELADRGKRVILLEQEPAHFIGGQAHWSLGGLFMVDTPEQRRMGIRDSLDLAQRD
WAGSAQFDRPEDQSPRQWAKAYLEFAAGDMRAWLHDLGLRWFPVVGWAERGDGRAEGHGNSVPRFHITWGTGPGVVAPFA
QRVHAHVATGRIDARFRHQVSHIIQQGGHIKGVSGEVLADDQGPIGAQTNRHEVGEFEVYAPSLIVASGGIGGNLEMVRE
NWPTERLGPAPSRMVSGVPAHVDGRMLKVAQAAGGHIINGDRMWHYCEGLRNWDPIWPNHGIRILPGPSSLWFDAHGTRL
PDPALPGFDTLGTLKAILASGQDYSWFILSQKIIQKEFALSGSEQNPDLTSGTWAEVLRARIFSGGKAPVPVEAFKKHGA
DFVVAETLSDLVRGMNEIADVPLDEAHIRAQIEARDAQVDNPFAKDRQIQAIHAARNYRGDRLIRTAKPHRLLDRANGPL
IAVRLSILTRKTLGGLHTTLESQMIGADGAPLPGLFAVGEAAGFGGGGYHGYNALEGTFLGGCLFSGRQAGRSDQIA

Sequences:

>Translated_557_residues
MAAAQRDNHADVIVIGAGLAGLVAANELADRGKRVILLEQEPAHFIGGQAHWSLGGLFMVDTPEQRRMGIRDSLDLAQRD
WAGSAQFDRPEDQSPRQWAKAYLEFAAGDMRAWLHDLGLRWFPVVGWAERGDGRAEGHGNSVPRFHITWGTGPGVVAPFA
QRVHAHVATGRIDARFRHQVSHIIQQGGHIKGVSGEVLADDQGPIGAQTNRHEVGEFEVYAPSLIVASGGIGGNLEMVRE
NWPTERLGPAPSRMVSGVPAHVDGRMLKVAQAAGGHIINGDRMWHYCEGLRNWDPIWPNHGIRILPGPSSLWFDAHGTRL
PDPALPGFDTLGTLKAILASGQDYSWFILSQKIIQKEFALSGSEQNPDLTSGTWAEVLRARIFSGGKAPVPVEAFKKHGA
DFVVAETLSDLVRGMNEIADVPLDEAHIRAQIEARDAQVDNPFAKDRQIQAIHAARNYRGDRLIRTAKPHRLLDRANGPL
IAVRLSILTRKTLGGLHTTLESQMIGADGAPLPGLFAVGEAAGFGGGGYHGYNALEGTFLGGCLFSGRQAGRSDQIA
>Mature_556_residues
AAAQRDNHADVIVIGAGLAGLVAANELADRGKRVILLEQEPAHFIGGQAHWSLGGLFMVDTPEQRRMGIRDSLDLAQRDW
AGSAQFDRPEDQSPRQWAKAYLEFAAGDMRAWLHDLGLRWFPVVGWAERGDGRAEGHGNSVPRFHITWGTGPGVVAPFAQ
RVHAHVATGRIDARFRHQVSHIIQQGGHIKGVSGEVLADDQGPIGAQTNRHEVGEFEVYAPSLIVASGGIGGNLEMVREN
WPTERLGPAPSRMVSGVPAHVDGRMLKVAQAAGGHIINGDRMWHYCEGLRNWDPIWPNHGIRILPGPSSLWFDAHGTRLP
DPALPGFDTLGTLKAILASGQDYSWFILSQKIIQKEFALSGSEQNPDLTSGTWAEVLRARIFSGGKAPVPVEAFKKHGAD
FVVAETLSDLVRGMNEIADVPLDEAHIRAQIEARDAQVDNPFAKDRQIQAIHAARNYRGDRLIRTAKPHRLLDRANGPLI
AVRLSILTRKTLGGLHTTLESQMIGADGAPLPGLFAVGEAAGFGGGGYHGYNALEGTFLGGCLFSGRQAGRSDQIA

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, but the ketosteroid dehydrogenase activity is low compared to KsdD in the cholesterol degradation process. The low activ

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60275; Mature: 60144

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAQRDNHADVIVIGAGLAGLVAANELADRGKRVILLEQEPAHFIGGQAHWSLGGLFMV
CCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCEECCCCEEEE
DTPEQRRMGIRDSLDLAQRDWAGSAQFDRPEDQSPRQWAKAYLEFAAGDMRAWLHDLGLR
ECCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCC
WFPVVGWAERGDGRAEGHGNSVPRFHITWGTGPGVVAPFAQRVHAHVATGRIDARFRHQV
EEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
SHIIQQGGHIKGVSGEVLADDQGPIGAQTNRHEVGEFEVYAPSLIVASGGIGGNLEMVRE
HHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCHHHHHC
NWPTERLGPAPSRMVSGVPAHVDGRMLKVAQAAGGHIINGDRMWHYCEGLRNWDPIWPNH
CCCCHHCCCCHHHHHCCCCCCCCCHHEEEHHHCCCEEECCCCHHHHHHCCCCCCCCCCCC
GIRILPGPSSLWFDAHGTRLPDPALPGFDTLGTLKAILASGQDYSWFILSQKIIQKEFAL
CEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHC
SGSEQNPDLTSGTWAEVLRARIFSGGKAPVPVEAFKKHGADFVVAETLSDLVRGMNEIAD
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHC
VPLDEAHIRAQIEARDAQVDNPFAKDRQIQAIHAARNYRGDRLIRTAKPHRLLDRANGPL
CCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHCCCCCE
IAVRLSILTRKTLGGLHTTLESQMIGADGAPLPGLFAVGEAAGFGGGGYHGYNALEGTFL
EEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHH
GGCLFSGRQAGRSDQIA
HHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
AAAQRDNHADVIVIGAGLAGLVAANELADRGKRVILLEQEPAHFIGGQAHWSLGGLFMV
CCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCCEECCCCEEEE
DTPEQRRMGIRDSLDLAQRDWAGSAQFDRPEDQSPRQWAKAYLEFAAGDMRAWLHDLGLR
ECCHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCC
WFPVVGWAERGDGRAEGHGNSVPRFHITWGTGPGVVAPFAQRVHAHVATGRIDARFRHQV
EEEEEEEEECCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
SHIIQQGGHIKGVSGEVLADDQGPIGAQTNRHEVGEFEVYAPSLIVASGGIGGNLEMVRE
HHHHHCCCCEECCCCCEEECCCCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCHHHHHC
NWPTERLGPAPSRMVSGVPAHVDGRMLKVAQAAGGHIINGDRMWHYCEGLRNWDPIWPNH
CCCCHHCCCCHHHHHCCCCCCCCCHHEEEHHHCCCEEECCCCHHHHHHCCCCCCCCCCCC
GIRILPGPSSLWFDAHGTRLPDPALPGFDTLGTLKAILASGQDYSWFILSQKIIQKEFAL
CEEEEECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHC
SGSEQNPDLTSGTWAEVLRARIFSGGKAPVPVEAFKKHGADFVVAETLSDLVRGMNEIAD
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEHHHHHHHHHHHHHHHHC
VPLDEAHIRAQIEARDAQVDNPFAKDRQIQAIHAARNYRGDRLIRTAKPHRLLDRANGPL
CCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCHHHHHCCCCCE
IAVRLSILTRKTLGGLHTTLESQMIGADGAPLPGLFAVGEAAGFGGGGYHGYNALEGTFL
EEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHH
GGCLFSGRQAGRSDQIA
HHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA