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The map label for this gene is aatA [H]

Identifier: 99081575

GI number: 99081575

Start: 1828535

End: 1829737

Strand: Direct

Name: aatA [H]

Synonym: TM1040_1734

Alternate gene names: 99081575

Gene position: 1828535-1829737 (Clockwise)

Preceding gene: 99081571

Following gene: 99081576

Centisome position: 57.12

GC content: 58.94

Gene sequence:

>1203_bases
ATGTCCGTTCTTTCTGCGACACTTTCCCGCGTGAAGCCTTCCCCGACCATTGCCGTCACCAATAAGGCGCGTGAATTGAA
AGCCGCCGGTCGCGACGTGATCGGCCTTGGTGCGGGGGAACCGGATTTCGACACGCCACAATCCATCAAGGATGCCGCTG
TCCGTGCCATTGCCGAGGGCAAGACCAAATACACAGCCGTCGATGGCATCCCGGAGCTGAAGCAGACCATCTGCGAAAAG
TTCAAGCGTGACAATGGCCTGGACTATCGCCCGGAGCAGGTCACGGTAAACTCTGGCGGCAAGCAGACGCTGTATAACGC
CCTGATGGCGACCCTCAATCCCGGCGATGAGGTGATCATCCCCGCGCCCTATTGGGTGAGCTATCCTGACATGGTGCTCC
TTGCAGGAGGCACTCCGGTTCCGGTGGAGGCCAGCCTTGAGAGCAGCTTCAAACTGACGCCCGATCAGTTGGAGGCCGCC
ATCACCGACAAGACCAAATGGTTCATCTTCAATTCTCCCTCCAACCCGACCGGAGCCGGATATTCGCGCGCCGAATTGAA
AGCTCTGACGGATGTCTTGATGCGTCATCCCCATGTCTGGGTGATGACCGATGACATGTATGAACACCTCGCCTATGACG
ATTTCGAATTCTGCACACCGGCGCAGGTTGAACCGGGACTCTATGACCGCACCCTCACCTGCAACGGGGTTTCCAAAGCC
TATGCGATGACTGGCTGGCGGATCGGCTATGCGGCGGGTCCGGAAACTCTGATTGCGGCGATGCGCAAGGTGCAGTCGCA
GTCTACCTCGAACCCCTGTTCGGTCAGCCAATATGCCGCGCTCGAAGCGCTCACGGGGCCGCAGGATTTCCTCGCCAGCA
ACAATGAGATCTTCGTGCGGCGGCGCAATCTGGTGGTGTCGATGCTGTCGGAGATCGATGGCTTGACCTGCCCGGTGCCG
GAGGGCGCTTTTTATGTCTACCCCTCGATCGCGGGTCTCATTGGCAAGACAACGCCAAAAGGCGTAACCATCAACAGCGA
TGAGGATTTTGCCACCGCCCTTCTGGAAGAGGCCGATGTGGCCGTGGTGTTTGGCGCAGCCTTTGGCCTCTCGCCGAATT
TTCGTGTGAGCTATGCAACCTCCGATGACGCCCTCAAGGAAGCCTGCACGCGCATCCAGCGCTTCTGCGCCTCGCTCAGC
TGA

Upstream 100 bases:

>100_bases
TCGTCGTGTCGGTCATGCGGTCTCTCCTAAGTGGACGACTTGATTGCCGTTTGGCGCCACCCTAAGAGTTTTGCAGATGA
CATTCAAATCGAGGTCCGAC

Downstream 100 bases:

>100_bases
TCTCTGAGCGCCACGACACAAAGTCTTGCGCTGCGCTTTGCGCATCGCGGTGGGGCGGCGGCGGCCGCCGCCCGGCCCAA
CCGGGCCAATGTGGCGTGCC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSVLSATLSRVKPSPTIAVTNKARELKAAGRDVIGLGAGEPDFDTPQSIKDAAVRAIAEGKTKYTAVDGIPELKQTICEK
FKRDNGLDYRPEQVTVNSGGKQTLYNALMATLNPGDEVIIPAPYWVSYPDMVLLAGGTPVPVEASLESSFKLTPDQLEAA
ITDKTKWFIFNSPSNPTGAGYSRAELKALTDVLMRHPHVWVMTDDMYEHLAYDDFEFCTPAQVEPGLYDRTLTCNGVSKA
YAMTGWRIGYAAGPETLIAAMRKVQSQSTSNPCSVSQYAALEALTGPQDFLASNNEIFVRRRNLVVSMLSEIDGLTCPVP
EGAFYVYPSIAGLIGKTTPKGVTINSDEDFATALLEEADVAVVFGAAFGLSPNFRVSYATSDDALKEACTRIQRFCASLS

Sequences:

>Translated_400_residues
MSVLSATLSRVKPSPTIAVTNKARELKAAGRDVIGLGAGEPDFDTPQSIKDAAVRAIAEGKTKYTAVDGIPELKQTICEK
FKRDNGLDYRPEQVTVNSGGKQTLYNALMATLNPGDEVIIPAPYWVSYPDMVLLAGGTPVPVEASLESSFKLTPDQLEAA
ITDKTKWFIFNSPSNPTGAGYSRAELKALTDVLMRHPHVWVMTDDMYEHLAYDDFEFCTPAQVEPGLYDRTLTCNGVSKA
YAMTGWRIGYAAGPETLIAAMRKVQSQSTSNPCSVSQYAALEALTGPQDFLASNNEIFVRRRNLVVSMLSEIDGLTCPVP
EGAFYVYPSIAGLIGKTTPKGVTINSDEDFATALLEEADVAVVFGAAFGLSPNFRVSYATSDDALKEACTRIQRFCASLS
>Mature_399_residues
SVLSATLSRVKPSPTIAVTNKARELKAAGRDVIGLGAGEPDFDTPQSIKDAAVRAIAEGKTKYTAVDGIPELKQTICEKF
KRDNGLDYRPEQVTVNSGGKQTLYNALMATLNPGDEVIIPAPYWVSYPDMVLLAGGTPVPVEASLESSFKLTPDQLEAAI
TDKTKWFIFNSPSNPTGAGYSRAELKALTDVLMRHPHVWVMTDDMYEHLAYDDFEFCTPAQVEPGLYDRTLTCNGVSKAY
AMTGWRIGYAAGPETLIAAMRKVQSQSTSNPCSVSQYAALEALTGPQDFLASNNEIFVRRRNLVVSMLSEIDGLTCPVPE
GAFYVYPSIAGLIGKTTPKGVTINSDEDFATALLEEADVAVVFGAAFGLSPNFRVSYATSDDALKEACTRIQRFCASLS

Specific function: Required for symbiotic nitrogen fixation [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=358, Percent_Identity=28.7709497206704, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI169881279, Length=358, Percent_Identity=28.7709497206704, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI56713254, Length=326, Percent_Identity=29.7546012269939, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI56713256, Length=326, Percent_Identity=29.7546012269939, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI169881281, Length=365, Percent_Identity=26.027397260274, Blast_Score=115, Evalue=5e-26,
Organism=Homo sapiens, GI4507369, Length=422, Percent_Identity=24.8815165876777, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1786816, Length=378, Percent_Identity=27.2486772486773, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788627, Length=392, Percent_Identity=26.2755102040816, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1788722, Length=393, Percent_Identity=30.5343511450382, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71994472, Length=395, Percent_Identity=27.5949367088608, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71994476, Length=395, Percent_Identity=27.5949367088608, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=412, Percent_Identity=26.2135922330097, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17567663, Length=378, Percent_Identity=24.8677248677249, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=314, Percent_Identity=28.9808917197452, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=345, Percent_Identity=24.6376811594203, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=344, Percent_Identity=22.093023255814, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573069, Length=322, Percent_Identity=28.8819875776398, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24646114, Length=322, Percent_Identity=28.8819875776398, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28573067, Length=322, Percent_Identity=28.8819875776398, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28573065, Length=322, Percent_Identity=28.8819875776398, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI18859735, Length=324, Percent_Identity=24.6913580246914, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43230; Mature: 43099

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLSATLSRVKPSPTIAVTNKARELKAAGRDVIGLGAGEPDFDTPQSIKDAAVRAIAEG
CCHHHHHHHHCCCCCCEEECCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCC
KTKYTAVDGIPELKQTICEKFKRDNGLDYRPEQVTVNSGGKQTLYNALMATLNPGDEVII
CCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPDMVLLAGGTPVPVEASLESSFKLTPDQLEAAITDKTKWFIFNSPSNPTGAG
CCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
YSRAELKALTDVLMRHPHVWVMTDDMYEHLAYDDFEFCTPAQVEPGLYDRTLTCNGVSKA
CCHHHHHHHHHHHHHCCEEEEEECHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHH
YAMTGWRIGYAAGPETLIAAMRKVQSQSTSNPCSVSQYAALEALTGPQDFLASNNEIFVR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHCCCCEEEEE
RRNLVVSMLSEIDGLTCPVPEGAFYVYPSIAGLIGKTTPKGVTINSDEDFATALLEEADV
HHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHCCCCCCCEEECCCCHHHHHHHHCCCE
AVVFGAAFGLSPNFRVSYATSDDALKEACTRIQRFCASLS
EEEEEEHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SVLSATLSRVKPSPTIAVTNKARELKAAGRDVIGLGAGEPDFDTPQSIKDAAVRAIAEG
CHHHHHHHHCCCCCCEEECCCHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCC
KTKYTAVDGIPELKQTICEKFKRDNGLDYRPEQVTVNSGGKQTLYNALMATLNPGDEVII
CCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCEEE
PAPYWVSYPDMVLLAGGTPVPVEASLESSFKLTPDQLEAAITDKTKWFIFNSPSNPTGAG
CCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCCCC
YSRAELKALTDVLMRHPHVWVMTDDMYEHLAYDDFEFCTPAQVEPGLYDRTLTCNGVSKA
CCHHHHHHHHHHHHHCCEEEEEECHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCHHH
YAMTGWRIGYAAGPETLIAAMRKVQSQSTSNPCSVSQYAALEALTGPQDFLASNNEIFVR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHCCCCEEEEE
RRNLVVSMLSEIDGLTCPVPEGAFYVYPSIAGLIGKTTPKGVTINSDEDFATALLEEADV
HHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHCCCCCCCEEECCCCHHHHHHHHCCCE
AVVFGAAFGLSPNFRVSYATSDDALKEACTRIQRFCASLS
EEEEEEHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2019560; 8096210; 11481430 [H]