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The map label for this gene is munIM [H]

Identifier: 99081520

GI number: 99081520

Start: 1777291

End: 1777863

Strand: Reverse

Name: munIM [H]

Synonym: TM1040_1679

Alternate gene names: 99081520

Gene position: 1777863-1777291 (Counterclockwise)

Preceding gene: 99081521

Following gene: 99081519

Centisome position: 55.54

GC content: 56.72

Gene sequence:

>573_bases
ATGGCAGCATTCTCAAATTTCGCTGACATGCCGCTGTTCCGCTATGGCCTGATCATGGCAGATCCGCCGTGGTCTTATGA
GAATTGGTCGGCAAAAGGAGACCACAAGAACGCAAGCGCGAAATATGATTGCATCGGCCTGGACGACATCAAGGGAATGC
AGGTCGGTCATCTAGCGGCTGAAAGCTGCGTTTTGTGGCTTTGGGCCACCAACCCGCTGCTGGATAAGGCTTTCGAGGTC
ATGGAGGCATGGGGGTTCCAATCCAAGACCGCAGGCCATTGGTCAAAGAAGACCTCCGGCGGTAAGCAAGCCTTCGGCAC
GGGCTATATCCTTCGTTGTGCCGGTGAACCCTTCCTGATCGGCACCGTTGGGAATCCAAAGACCGCGAGAAACGTTCGAT
CGGTAATCGAAGGGCCCTTGCGCGAGCATTCTCGAAAGCCAGAGGAGGCTTTCGCAGCAGCTGAGGCCCTTTGCGGTGAT
GTTCCTAGGCTAGAGCTTTTCAGCCGCCAAGAGCGGACAGGCTGGGACGTGTTCGGGAACGAGGTCGACAAGTTTCAGGG
GGCGGCCGCATGA

Upstream 100 bases:

>100_bases
TCGAGCGCAAGAAGCTGATCCTCGCGGAGACTATCGCTGAGCGCACACGGATCATGAACCGCTGCATCCGCCGGATGCGC
AGAGCCGCGGGTAAGGACTG

Downstream 100 bases:

>100_bases
AGTCCACCACCATTCGCCTCTCTTGGCCCCGCCGCGCCCTCTGGGACAATGAGAAGGCCAGCCACATGGTGAGGGCCGCA
GCCAAGCGCACACAGCGCAA

Product: MT-A70

Products: NA

Alternate protein names: Adenine-specific methyltransferase MunI; M.MunI [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MAAFSNFADMPLFRYGLIMADPPWSYENWSAKGDHKNASAKYDCIGLDDIKGMQVGHLAAESCVLWLWATNPLLDKAFEV
MEAWGFQSKTAGHWSKKTSGGKQAFGTGYILRCAGEPFLIGTVGNPKTARNVRSVIEGPLREHSRKPEEAFAAAEALCGD
VPRLELFSRQERTGWDVFGNEVDKFQGAAA

Sequences:

>Translated_190_residues
MAAFSNFADMPLFRYGLIMADPPWSYENWSAKGDHKNASAKYDCIGLDDIKGMQVGHLAAESCVLWLWATNPLLDKAFEV
MEAWGFQSKTAGHWSKKTSGGKQAFGTGYILRCAGEPFLIGTVGNPKTARNVRSVIEGPLREHSRKPEEAFAAAEALCGD
VPRLELFSRQERTGWDVFGNEVDKFQGAAA
>Mature_189_residues
AAFSNFADMPLFRYGLIMADPPWSYENWSAKGDHKNASAKYDCIGLDDIKGMQVGHLAAESCVLWLWATNPLLDKAFEVM
EAWGFQSKTAGHWSKKTSGGKQAFGTGYILRCAGEPFLIGTVGNPKTARNVRSVIEGPLREHSRKPEEAFAAAEALCGDV
PRLELFSRQERTGWDVFGNEVDKFQGAAA

Specific function: This methylase recognizes the double-stranded sequence CAATTG, causes specific methylation on A-3 on both strands, and protects the DNA from cleavage by the MunI endonuclease [H]

COG id: COG4725

COG function: function code TK; Transcriptional activator, adenine-specific DNA methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MT-A70-like family [H]

Homologues:

Organism=Homo sapiens, GI145275206, Length=196, Percent_Identity=30.1020408163265, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321246, Length=178, Percent_Identity=29.7752808988764, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR007757 [H]

Pfam domain/function: PF05063 MT-A70 [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 20908; Mature: 20777

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51143 MT_A70

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFSNFADMPLFRYGLIMADPPWSYENWSAKGDHKNASAKYDCIGLDDIKGMQVGHLAA
CCCCCCCCCCCHHHHCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHH
ESCVLWLWATNPLLDKAFEVMEAWGFQSKTAGHWSKKTSGGKQAFGTGYILRCAGEPFLI
CCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEE
GTVGNPKTARNVRSVIEGPLREHSRKPEEAFAAAEALCGDVPRLELFSRQERTGWDVFGN
EECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHCC
EVDKFQGAAA
HHHHHCCCCC
>Mature Secondary Structure 
AAFSNFADMPLFRYGLIMADPPWSYENWSAKGDHKNASAKYDCIGLDDIKGMQVGHLAA
CCCCCCCCCCHHHHCEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHH
ESCVLWLWATNPLLDKAFEVMEAWGFQSKTAGHWSKKTSGGKQAFGTGYILRCAGEPFLI
CCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEE
GTVGNPKTARNVRSVIEGPLREHSRKPEEAFAAAEALCGDVPRLELFSRQERTGWDVFGN
EECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHCC
EVDKFQGAAA
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8181741 [H]