Click here to switch to the map view.

The map label for this gene is siaP [H]

Identifier: 99081432

GI number: 99081432

Start: 1702034

End: 1703014

Strand: Reverse

Name: siaP [H]

Synonym: TM1040_1591

Alternate gene names: 99081432

Gene position: 1703014-1702034 (Counterclockwise)

Preceding gene: 99081433

Following gene: 99081431

Centisome position: 53.2

GC content: 60.04

Gene sequence:

>981_bases
ATGAATGTCATTTGGAAAACGATCACAGGCGCCGCATTTGTGCTGTCGAGTACGGTTGCCCCCCAGGCCAAGGAGTTTCG
TCTTGGCCTGATCACACCGCCGCCACACATCTGGACCAAAGCTGCCGAAGCCTTTGGCGCAGATATCGCCAAGGCCAGCG
ATGGGGCCCATAGCGTCACCGTGTTTCCCGCGCGCCAGCTCGGCAACGAGGCAGAGATGCTGCAACAATTGCAGACCGGC
GCCCTGGACATGGCGTTTATGACGGTAGCCGAAGTGTCCAATCGCGCCCCGGATTTTGGCGCGCTTTATGCGCCCTATCT
CGCGGAGGACATCGCCCACGCAGGCCGAATCCTGCGCAGTGAAACCGCCACCTCCATGCTGGCACAATTGCCTGCCAAAA
CAGGTGTTGTCGGCACGGGATATGGCATGGCGGGGCTGCGTCAGATCGTGACCCGTGGTGAGGTCAACAGTGTTGACGAT
CTTGCGGGTCTGAAGCTGCGGATCACGCCCTTCGAGCCGATCCTCGATTTCTACAATGCCATTGGCGCCGCCCCAACGCC
GATGCCGCTGCCCTCGGTCTATGATGCGCTGGCCAATGGTCAGGTCGATGCGATCGACATGGATGCCGAACTGATCTGGG
TGCTCAAATACTACGAACATGCGGATACGGTTGTGCAATCAAACCACATGATGTTCCCGATGGTGGGGCTTGTCTCTGCA
CGGGTCTGGGCGGGCCTTTCGGAGGCGGACCGTGCCCTGATCGGAGATCTCATGGCGCGCCATGTAGACAGCACGATCGA
TACCTATGTGGAGAAAGAACAGCTCTGGCTGGATGAGATCAAGGCGACGGGGCGCACCTATAAGACGGTCGATGCGGCAT
TCTTTGGTGAGGCGGTCGAGAGCTGGAATGCGGTTTGGTCGGAGCGCTCGCAAATGCTCGGGCCATTACGCGCAGCGGCT
GCGGCCACCGCGCGGGACTGA

Upstream 100 bases:

>100_bases
GTCCACACTGCGGCGCGCTCCATCCCGGCAAGGGGAAGCCACCTGCAGATTGGGTGCAGCTTTGATGATCAAAACAATAA
GCAAAACAGGGAATTGGCCA

Downstream 100 bases:

>100_bases
CCCTCAACAGCCATCGGCGGCGGCCCCTCGCGAGAGGGGCGCGCCAGTGAGGCGGAGAGCGAAATGATCGGACGTATCTC
GGCAGCCTGGGCACGCTGTG

Product: TRAP dicarboxylate transporter- DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNVIWKTITGAAFVLSSTVAPQAKEFRLGLITPPPHIWTKAAEAFGADIAKASDGAHSVTVFPARQLGNEAEMLQQLQTG
ALDMAFMTVAEVSNRAPDFGALYAPYLAEDIAHAGRILRSETATSMLAQLPAKTGVVGTGYGMAGLRQIVTRGEVNSVDD
LAGLKLRITPFEPILDFYNAIGAAPTPMPLPSVYDALANGQVDAIDMDAELIWVLKYYEHADTVVQSNHMMFPMVGLVSA
RVWAGLSEADRALIGDLMARHVDSTIDTYVEKEQLWLDEIKATGRTYKTVDAAFFGEAVESWNAVWSERSQMLGPLRAAA
AATARD

Sequences:

>Translated_326_residues
MNVIWKTITGAAFVLSSTVAPQAKEFRLGLITPPPHIWTKAAEAFGADIAKASDGAHSVTVFPARQLGNEAEMLQQLQTG
ALDMAFMTVAEVSNRAPDFGALYAPYLAEDIAHAGRILRSETATSMLAQLPAKTGVVGTGYGMAGLRQIVTRGEVNSVDD
LAGLKLRITPFEPILDFYNAIGAAPTPMPLPSVYDALANGQVDAIDMDAELIWVLKYYEHADTVVQSNHMMFPMVGLVSA
RVWAGLSEADRALIGDLMARHVDSTIDTYVEKEQLWLDEIKATGRTYKTVDAAFFGEAVESWNAVWSERSQMLGPLRAAA
AATARD
>Mature_326_residues
MNVIWKTITGAAFVLSSTVAPQAKEFRLGLITPPPHIWTKAAEAFGADIAKASDGAHSVTVFPARQLGNEAEMLQQLQTG
ALDMAFMTVAEVSNRAPDFGALYAPYLAEDIAHAGRILRSETATSMLAQLPAKTGVVGTGYGMAGLRQIVTRGEVNSVDD
LAGLKLRITPFEPILDFYNAIGAAPTPMPLPSVYDALANGQVDAIDMDAELIWVLKYYEHADTVVQSNHMMFPMVGLVSA
RVWAGLSEADRALIGDLMARHVDSTIDTYVEKEQLWLDEIKATGRTYKTVDAAFFGEAVESWNAVWSERSQMLGPLRAAA
AATARD

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

Organism=Escherichia coli, GI1790004, Length=255, Percent_Identity=26.6666666666667, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 35189; Mature: 35189

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIWKTITGAAFVLSSTVAPQAKEFRLGLITPPPHIWTKAAEAFGADIAKASDGAHSVT
CCCCHHHHHHHHHHHHHHCCCCCHHCEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCEEE
VFPARQLGNEAEMLQQLQTGALDMAFMTVAEVSNRAPDFGALYAPYLAEDIAHAGRILRS
EEEHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ETATSMLAQLPAKTGVVGTGYGMAGLRQIVTRGEVNSVDDLAGLKLRITPFEPILDFYNA
HHHHHHHHHCCHHCCCEECCCCHHHHHHHHHCCCCCCCHHHCCCEEEECCHHHHHHHHHH
IGAAPTPMPLPSVYDALANGQVDAIDMDAELIWVLKYYEHADTVVQSNHMMFPMVGLVSA
HCCCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RVWAGLSEADRALIGDLMARHVDSTIDTYVEKEQLWLDEIKATGRTYKTVDAAFFGEAVE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SWNAVWSERSQMLGPLRAAAAATARD
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNVIWKTITGAAFVLSSTVAPQAKEFRLGLITPPPHIWTKAAEAFGADIAKASDGAHSVT
CCCCHHHHHHHHHHHHHHCCCCCHHCEEECCCCCCHHHHHHHHHHCCHHHHCCCCCCEEE
VFPARQLGNEAEMLQQLQTGALDMAFMTVAEVSNRAPDFGALYAPYLAEDIAHAGRILRS
EEEHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ETATSMLAQLPAKTGVVGTGYGMAGLRQIVTRGEVNSVDDLAGLKLRITPFEPILDFYNA
HHHHHHHHHCCHHCCCEECCCCHHHHHHHHHCCCCCCCHHHCCCEEEECCHHHHHHHHHH
IGAAPTPMPLPSVYDALANGQVDAIDMDAELIWVLKYYEHADTVVQSNHMMFPMVGLVSA
HCCCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RVWAGLSEADRALIGDLMARHVDSTIDTYVEKEQLWLDEIKATGRTYKTVDAAFFGEAVE
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SWNAVWSERSQMLGPLRAAAAATARD
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA