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The map label for this gene is selU [H]

Identifier: 99081386

GI number: 99081386

Start: 1652518

End: 1653561

Strand: Reverse

Name: selU [H]

Synonym: TM1040_1545

Alternate gene names: 99081386

Gene position: 1653561-1652518 (Counterclockwise)

Preceding gene: 99081388

Following gene: 99081378

Centisome position: 51.66

GC content: 61.3

Gene sequence:

>1044_bases
ATGTTTCAAACTCTTTCCGATTTTCTCGCGCATGGGCATGACACGGTGATCGATGTGCGCAGCCCGGCGGAATACGCCGA
GGATCACGTGCCCGGCGCGATCAATCTGCCAGTGCTAGACAACGCCGAACGCGCCGACGTGGGCACAATTTATGTGCAGC
AGAGCCCGTTTCTGGCGCGCAAGATCGGGGCAGCGATGGTGTTTCGCAACGCCGCTGACCATATTGAACATCGGCTGAGC
CACCACGAAGGCAGTTGGAAACCTCTGGTCTATTGCTGGCGCGGCGGTCAGCGCTCCGGTAGCTTTACCTGGATGCTGAG
CCAGATTGGCTGGCGGGCCGAAGTGGTCAAGGGCGGTTATCAGAGCTATCGCCGGCTTGTGCATCAGGCGATGTATGAGG
CGCCGCTTGCGCATCGTTTGATGCTGCTCGACGGGCTCACTGGAACCGCCAAGACCGAGATCTTGAAACAGGTCGCCGAG
ATGGGCGGCCAGGTGTTGGATCTCGAAGGCTTTGCGGGGCATCGTGGCTCGCTCTTGGGCGAGATGCCGGGCGGGCAGCC
AAGTCAGAAACGCTTTGAAAGCTACATCGCCTGTGCTCTTGCCCAGATGGATCCGGCACGTCCGGTGCTCGTTGAGGCAG
AAGCCAGCAAGATCGGCGCACGGATCCTGCCTCCGAGCCTCTGGGATGCCATGAAGGCGGCGCCACGGATTGATCTTGAG
GTGCCCTTCGCGGCGCGTTGTGCCTATTTGCTGGAGGCTTACGACGACATCCTGTCGAACGCAGAGACCCTGCGCGAAAA
GCTCGGACTTCTGCGCGAGCACCGCTCAGGCGCTGTAGTAGATGCCTGGTTCGAGCTCATCGCGGCGGGGGATAAACCTG
CGCTGGTGGCGCGGCTGATGGCGGATCACTATGATCCGGCCTATCGCAAGGCGCGCAGCCGATATGAGGTGAGCGACCAG
CGCAAGGTTGCCTTGACGGGACTTGACGAGGCCGCGCGCAAACAGGCAGCTCAGCGGATCTTGGAGCTGCTCGACGCATC
CTGA

Upstream 100 bases:

>100_bases
CTGACATGGGCGTCGTCCGTTGCATGATTTCTGGGCGGAGTCTCCATGTTTCGTATTTTGTTGTCCGCCCTCTGCCCCTA
TGAGATGGGGCATGGCTCTC

Downstream 100 bases:

>100_bases
GCCTTAGAGGGCCAAGAGCGCTCCTGCTAACGGATCACGATACCTTGGTCTGCATCACGTATTTCTCCAATCTTTGCAGC
GTGATAGCCATGGTTTTTCA

Product: tRNA 2-selenouridine synthase

Products: NA

Alternate protein names: Selenophosphate-dependent tRNA 2-selenouridine synthase [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MFQTLSDFLAHGHDTVIDVRSPAEYAEDHVPGAINLPVLDNAERADVGTIYVQQSPFLARKIGAAMVFRNAADHIEHRLS
HHEGSWKPLVYCWRGGQRSGSFTWMLSQIGWRAEVVKGGYQSYRRLVHQAMYEAPLAHRLMLLDGLTGTAKTEILKQVAE
MGGQVLDLEGFAGHRGSLLGEMPGGQPSQKRFESYIACALAQMDPARPVLVEAEASKIGARILPPSLWDAMKAAPRIDLE
VPFAARCAYLLEAYDDILSNAETLREKLGLLREHRSGAVVDAWFELIAAGDKPALVARLMADHYDPAYRKARSRYEVSDQ
RKVALTGLDEAARKQAAQRILELLDAS

Sequences:

>Translated_347_residues
MFQTLSDFLAHGHDTVIDVRSPAEYAEDHVPGAINLPVLDNAERADVGTIYVQQSPFLARKIGAAMVFRNAADHIEHRLS
HHEGSWKPLVYCWRGGQRSGSFTWMLSQIGWRAEVVKGGYQSYRRLVHQAMYEAPLAHRLMLLDGLTGTAKTEILKQVAE
MGGQVLDLEGFAGHRGSLLGEMPGGQPSQKRFESYIACALAQMDPARPVLVEAEASKIGARILPPSLWDAMKAAPRIDLE
VPFAARCAYLLEAYDDILSNAETLREKLGLLREHRSGAVVDAWFELIAAGDKPALVARLMADHYDPAYRKARSRYEVSDQ
RKVALTGLDEAARKQAAQRILELLDAS
>Mature_347_residues
MFQTLSDFLAHGHDTVIDVRSPAEYAEDHVPGAINLPVLDNAERADVGTIYVQQSPFLARKIGAAMVFRNAADHIEHRLS
HHEGSWKPLVYCWRGGQRSGSFTWMLSQIGWRAEVVKGGYQSYRRLVHQAMYEAPLAHRLMLLDGLTGTAKTEILKQVAE
MGGQVLDLEGFAGHRGSLLGEMPGGQPSQKRFESYIACALAQMDPARPVLVEAEASKIGARILPPSLWDAMKAAPRIDLE
VPFAARCAYLLEAYDDILSNAETLREKLGLLREHRSGAVVDAWFELIAAGDKPALVARLMADHYDPAYRKARSRYEVSDQ
RKVALTGLDEAARKQAAQRILELLDAS

Specific function: Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA [H]

COG id: COG2603

COG function: function code R; Predicted ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Escherichia coli, GI1786712, Length=332, Percent_Identity=31.0240963855422, Blast_Score=117, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR017582 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38426; Mature: 38426

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQTLSDFLAHGHDTVIDVRSPAEYAEDHVPGAINLPVLDNAERADVGTIYVQQSPFLAR
CCCCHHHHHHCCCCCEEECCCCHHHHHCCCCCEEECCCCCCCCCCCCEEEEEECCCHHHH
KIGAAMVFRNAADHIEHRLSHHEGSWKPLVYCWRGGQRSGSFTWMLSQIGWRAEVVKGGY
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEHHHHHCCHHHHHHHHH
QSYRRLVHQAMYEAPLAHRLMLLDGLTGTAKTEILKQVAEMGGQVLDLEGFAGHRGSLLG
HHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
EMPGGQPSQKRFESYIACALAQMDPARPVLVEAEASKIGARILPPSLWDAMKAAPRIDLE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCHHHHHHHHCCCCCCCC
VPFAARCAYLLEAYDDILSNAETLREKLGLLREHRSGAVVDAWFELIAAGDKPALVARLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
ADHYDPAYRKARSRYEVSDQRKVALTGLDEAARKQAAQRILELLDAS
HHCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFQTLSDFLAHGHDTVIDVRSPAEYAEDHVPGAINLPVLDNAERADVGTIYVQQSPFLAR
CCCCHHHHHHCCCCCEEECCCCHHHHHCCCCCEEECCCCCCCCCCCCEEEEEECCCHHHH
KIGAAMVFRNAADHIEHRLSHHEGSWKPLVYCWRGGQRSGSFTWMLSQIGWRAEVVKGGY
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEHHHHHCCHHHHHHHHH
QSYRRLVHQAMYEAPLAHRLMLLDGLTGTAKTEILKQVAEMGGQVLDLEGFAGHRGSLLG
HHHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCC
EMPGGQPSQKRFESYIACALAQMDPARPVLVEAEASKIGARILPPSLWDAMKAAPRIDLE
CCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCCHHHHHHHHCCCCCCCC
VPFAARCAYLLEAYDDILSNAETLREKLGLLREHRSGAVVDAWFELIAAGDKPALVARLM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
ADHYDPAYRKARSRYEVSDQRKVALTGLDEAARKQAAQRILELLDAS
HHCCCHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA