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The map label for this gene is dctD [H]

Identifier: 99081302

GI number: 99081302

Start: 1561389

End: 1562726

Strand: Reverse

Name: dctD [H]

Synonym: TM1040_1461

Alternate gene names: 99081302

Gene position: 1562726-1561389 (Counterclockwise)

Preceding gene: 99081303

Following gene: 99081301

Centisome position: 48.82

GC content: 60.31

Gene sequence:

>1338_bases
ATGGCACAGGCCATGAAAATTGCGATTGTGGATGACGAACAGGACATGCGTCAGTCGATCAGCCAATGGCTGGCACTGTC
TGGCTATGACACCGAAACATTCGCCAGCGCCGAGGATGCGCTCAAGGCGCTGGGGCCGGATTATCCGGGCATTGTGATTT
CCGACATCAAAATGCCGGGCATGGACGGGATGCAGTTCCTCAAGAAACTCATGGGATCGGACAGTTCGCTGCCGGTGATC
ATGATCACCGGTCACGGCGATGTGCCGATGGCAGTCGAGGCCATGCGCGTCGGAGCGTTTGATTTTCTCGAAAAACCCTT
CAACCCTGACCGCATGTCGGAGCTGGCCAAGCGCGCCACTGGCGCACGACGGTTGACGCTCGATACACGTGCGCTGCGCC
GCGAGCTTTCCGATGGCGGTCAAATCATGAAGAAGCTGATCGGAACCAGCCCCGTTATGGACCGCCTGCGCGAGGACATT
CTCGACCTCGGCCAGGCGGATGGCCATGTTCTGATCGACGGGGAAACCGGCACCGGCAAAACGCTCGTTGCGCATGCGCT
TCATGCCGTGGGCAGCCGCGCGGGCAAGAAATTCGTGCTGGTGTCCTGTGCCGCTCTTGAGGAAGAAGCACTCGCCAAAC
GTCTGTTTGGTCCCATGCAGCCCGAAGACAGCATGCTGCCCGCCGTCGAAGAGGCCCGTGGCGGCACCCTTGTGTTGGAG
GATGTCGAGGCGCTGAGCGAAGCCCTGCAGGCGAAGCTCTTGAGCTTTATCAACGAGCAGGGCATTCCGGGCGAGACCCG
CATCATTGCGATCTCCAACCTGCAGGAGGCGGGGAAAACCTCCGAGGATGTACTGCGCGCCGATCTCTTTTATCGCTTGG
CCGCGCTGCGCATCACGGTGCCCCCGTTGCGCCAGCGGGGCGAGGACATCCTGACGCTGTTCACTCGCCTGTCGGAACAA
TTTTCCGAGGAATACGGCTGCGAGGCGCCGCAGGTGACGGCGCAGGAGGCTGCGCAGCTCTTGCAGGCGCCGTGGCCCGG
TAACGTTCGTCAGCTGATCAACGTGGCAGAGCGCGCAGTGCTGCAATCGCGCCGCGGCTCAGGCACCATTGCCTCTCTCT
TGATGAGCGACCACGAAGATATGCAGCCGGTGATGACCACCGAAGGCAAGCCTCTGAAAGAATACGTCGAAGCCTTTGAA
CGTATGTTGATCGACAACACCATGCGTCGTCACAAGGGGTCTATCGCTTCGGTGATGGAAGAGCTCTGCCTGCCGCGTCG
AACGCTGAATGAGAAAATGGCGAAATACGGCCTGCAGCGCTCCGACTATCTCGGCTGA

Upstream 100 bases:

>100_bases
CAATTCCGATGCGGGCGGCGCGGTGTTTGAAATGCAACTGCCGATCCTGATGGACGGCATCGAGGCCGCCGAATAGGCGG
CACGACCTGGAGGGCAACTT

Downstream 100 bases:

>100_bases
TGCCCGCGGGGTATCTCTTTGATATGGATGGGCTGCTCCTTGATACGGAGCGGCTCACGCTGGACGCCTTTCTCGATTGC
GCGCCGGAGTTCGATCTGGA

Product: two component, sigma54 specific, Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MAQAMKIAIVDDEQDMRQSISQWLALSGYDTETFASAEDALKALGPDYPGIVISDIKMPGMDGMQFLKKLMGSDSSLPVI
MITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSELAKRATGARRLTLDTRALRRELSDGGQIMKKLIGTSPVMDRLREDI
LDLGQADGHVLIDGETGTGKTLVAHALHAVGSRAGKKFVLVSCAALEEEALAKRLFGPMQPEDSMLPAVEEARGGTLVLE
DVEALSEALQAKLLSFINEQGIPGETRIIAISNLQEAGKTSEDVLRADLFYRLAALRITVPPLRQRGEDILTLFTRLSEQ
FSEEYGCEAPQVTAQEAAQLLQAPWPGNVRQLINVAERAVLQSRRGSGTIASLLMSDHEDMQPVMTTEGKPLKEYVEAFE
RMLIDNTMRRHKGSIASVMEELCLPRRTLNEKMAKYGLQRSDYLG

Sequences:

>Translated_445_residues
MAQAMKIAIVDDEQDMRQSISQWLALSGYDTETFASAEDALKALGPDYPGIVISDIKMPGMDGMQFLKKLMGSDSSLPVI
MITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSELAKRATGARRLTLDTRALRRELSDGGQIMKKLIGTSPVMDRLREDI
LDLGQADGHVLIDGETGTGKTLVAHALHAVGSRAGKKFVLVSCAALEEEALAKRLFGPMQPEDSMLPAVEEARGGTLVLE
DVEALSEALQAKLLSFINEQGIPGETRIIAISNLQEAGKTSEDVLRADLFYRLAALRITVPPLRQRGEDILTLFTRLSEQ
FSEEYGCEAPQVTAQEAAQLLQAPWPGNVRQLINVAERAVLQSRRGSGTIASLLMSDHEDMQPVMTTEGKPLKEYVEAFE
RMLIDNTMRRHKGSIASVMEELCLPRRTLNEKMAKYGLQRSDYLG
>Mature_444_residues
AQAMKIAIVDDEQDMRQSISQWLALSGYDTETFASAEDALKALGPDYPGIVISDIKMPGMDGMQFLKKLMGSDSSLPVIM
ITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSELAKRATGARRLTLDTRALRRELSDGGQIMKKLIGTSPVMDRLREDIL
DLGQADGHVLIDGETGTGKTLVAHALHAVGSRAGKKFVLVSCAALEEEALAKRLFGPMQPEDSMLPAVEEARGGTLVLED
VEALSEALQAKLLSFINEQGIPGETRIIAISNLQEAGKTSEDVLRADLFYRLAALRITVPPLRQRGEDILTLFTRLSEQF
SEEYGCEAPQVTAQEAAQLLQAPWPGNVRQLINVAERAVLQSRRGSGTIASLLMSDHEDMQPVMTTEGKPLKEYVEAFER
MLIDNTMRRHKGSIASVMEELCLPRRTLNEKMAKYGLQRSDYLG

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=469, Percent_Identity=33.2622601279318, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI1790299, Length=470, Percent_Identity=30.4255319148936, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1790437, Length=457, Percent_Identity=30.6345733041575, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI1788905, Length=455, Percent_Identity=30.3296703296703, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1787583, Length=310, Percent_Identity=30.3225806451613, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=31.4465408805031, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87082117, Length=320, Percent_Identity=31.25, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789087, Length=342, Percent_Identity=30.9941520467836, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=31.0769230769231, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1786524, Length=250, Percent_Identity=34.4, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=33.7662337662338, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87081858, Length=292, Percent_Identity=29.4520547945205, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789809, Length=109, Percent_Identity=29.3577981651376, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082012, Length=121, Percent_Identity=36.3636363636364, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787487, Length=112, Percent_Identity=33.0357142857143, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787375, Length=149, Percent_Identity=26.1744966442953, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=123, Percent_Identity=29.2682926829268, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1789828, Length=333, Percent_Identity=26.1261261261261, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788191, Length=113, Percent_Identity=34.5132743362832, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48905; Mature: 48774

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAMKIAIVDDEQDMRQSISQWLALSGYDTETFASAEDALKALGPDYPGIVISDIKMPG
CCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
MDGMQFLKKLMGSDSSLPVIMITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSELAKRAT
CCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GARRLTLDTRALRRELSDGGQIMKKLIGTSPVMDRLREDILDLGQADGHVLIDGETGTGK
CCCEEEHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
TLVAHALHAVGSRAGKKFVLVSCAALEEEALAKRLFGPMQPEDSMLPAVEEARGGTLVLE
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEHH
DVEALSEALQAKLLSFINEQGIPGETRIIAISNLQEAGKTSEDVLRADLFYRLAALRITV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHCCC
PPLRQRGEDILTLFTRLSEQFSEEYGCEAPQVTAQEAAQLLQAPWPGNVRQLINVAERAV
CHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQSRRGSGTIASLLMSDHEDMQPVMTTEGKPLKEYVEAFERMLIDNTMRRHKGSIASVME
HHHCCCCHHHHHHHHHCCHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELCLPRRTLNEKMAKYGLQRSDYLG
HHHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AQAMKIAIVDDEQDMRQSISQWLALSGYDTETFASAEDALKALGPDYPGIVISDIKMPG
CCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCC
MDGMQFLKKLMGSDSSLPVIMITGHGDVPMAVEAMRVGAFDFLEKPFNPDRMSELAKRAT
CCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
GARRLTLDTRALRRELSDGGQIMKKLIGTSPVMDRLREDILDLGQADGHVLIDGETGTGK
CCCEEEHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCH
TLVAHALHAVGSRAGKKFVLVSCAALEEEALAKRLFGPMQPEDSMLPAVEEARGGTLVLE
HHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEHH
DVEALSEALQAKLLSFINEQGIPGETRIIAISNLQEAGKTSEDVLRADLFYRLAALRITV
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHCCCHHHHHHHHHHHHHHHHHCCC
PPLRQRGEDILTLFTRLSEQFSEEYGCEAPQVTAQEAAQLLQAPWPGNVRQLINVAERAV
CHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
LQSRRGSGTIASLLMSDHEDMQPVMTTEGKPLKEYVEAFERMLIDNTMRRHKGSIASVME
HHHCCCCHHHHHHHHHCCHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
ELCLPRRTLNEKMAKYGLQRSDYLG
HHHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]