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The map label for this gene is frr [H]

Identifier: 99081254

GI number: 99081254

Start: 1506544

End: 1507107

Strand: Reverse

Name: frr [H]

Synonym: TM1040_1413

Alternate gene names: 99081254

Gene position: 1507107-1506544 (Counterclockwise)

Preceding gene: 99081255

Following gene: 99081253

Centisome position: 47.08

GC content: 58.33

Gene sequence:

>564_bases
ATGTCTGAAGAGTTTGAACTGGACACCGATGATCTGAAACGCCGCATGGACGGCGCGATGGCGAATCTCAAAACAGAATT
CGCGTCGCTGCGCACCGGTCGCGCCTCCGCGTCGATGCTGGAACCGGTGATGGTGGATGCCTACGGGTCGATGACTCCGA
TCAACCAAGTGGGCACCGTGAACGTGCCCGAGCCGCGTATGGTGACCATCAATGTCTGGGACAAGGGTCTCGTTGGCAAA
GTTGAAAAAGCGATCCGCGAGTCGGGCCTCGGTATCAACCCGCAGCTTAATGGCACCATCATCATGCTGCCGATCCCCGA
GTTGAACGAGGAACGCCGCCGCGAGTTGACCAAGGTTGCCGGCCAATATGCCGAACACGCCCGCGTGTCGATCCGCAATG
TGCGCCGCGACGGGATGGATCAGATCAAGAAAGCCAAAGCCGACGGCATGTCCGAGGACGACCAGAAATTCTGGGAGACC
GAGGTTCAGGAACTGACCGACAAGATGATCAAGGCCGTGGACGCTGCGCTGGAGACCAAGCAAGCCGAAATCATGCAGGT
TTGA

Upstream 100 bases:

>100_bases
GAAGGTTTCGCGGGTGTTTGTCCGCCGAGATCGCTATACAATCTATACATGATGGCGTAAGAGCCATCCTCAAGACCGCC
TCAAGCAAGGGGAGAGCAGA

Downstream 100 bases:

>100_bases
TCAGCTCAGATGTCACTCGTCACAGATAGCGCAACGCCGCGTGCGGCTGGTGCGGGAGATCCTGCACCGGGCGTTGGTGA
CGGGCCGAAACATGTAGCGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSEEFELDTDDLKRRMDGAMANLKTEFASLRTGRASASMLEPVMVDAYGSMTPINQVGTVNVPEPRMVTINVWDKGLVGK
VEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTKVAGQYAEHARVSIRNVRRDGMDQIKKAKADGMSEDDQKFWET
EVQELTDKMIKAVDAALETKQAEIMQV

Sequences:

>Translated_187_residues
MSEEFELDTDDLKRRMDGAMANLKTEFASLRTGRASASMLEPVMVDAYGSMTPINQVGTVNVPEPRMVTINVWDKGLVGK
VEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTKVAGQYAEHARVSIRNVRRDGMDQIKKAKADGMSEDDQKFWET
EVQELTDKMIKAVDAALETKQAEIMQV
>Mature_186_residues
SEEFELDTDDLKRRMDGAMANLKTEFASLRTGRASASMLEPVMVDAYGSMTPINQVGTVNVPEPRMVTINVWDKGLVGKV
EKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTKVAGQYAEHARVSIRNVRRDGMDQIKKAKADGMSEDDQKFWETE
VQELTDKMIKAVDAALETKQAEIMQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=28.8888888888889, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI291042689, Length=155, Percent_Identity=32.258064516129, Blast_Score=92, Evalue=3e-19,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=46.3276836158192, Blast_Score=160, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24661488, Length=180, Percent_Identity=25.5555555555556, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20967; Mature: 20836

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEFELDTDDLKRRMDGAMANLKTEFASLRTGRASASMLEPVMVDAYGSMTPINQVGTV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
NVPEPRMVTINVWDKGLVGKVEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTKVA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
GQYAEHARVSIRNVRRDGMDQIKKAKADGMSEDDQKFWETEVQELTDKMIKAVDAALETK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEIMQV
HHHHHCC
>Mature Secondary Structure 
SEEFELDTDDLKRRMDGAMANLKTEFASLRTGRASASMLEPVMVDAYGSMTPINQVGTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCC
NVPEPRMVTINVWDKGLVGKVEKAIRESGLGINPQLNGTIIMLPIPELNEERRRELTKVA
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHH
GQYAEHARVSIRNVRRDGMDQIKKAKADGMSEDDQKFWETEVQELTDKMIKAVDAALETK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAEIMQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA