Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 99081246

GI number: 99081246

Start: 1498393

End: 1498875

Strand: Reverse

Name: fabZ

Synonym: TM1040_1405

Alternate gene names: 99081246

Gene position: 1498875-1498393 (Counterclockwise)

Preceding gene: 99081247

Following gene: 99081245

Centisome position: 46.83

GC content: 56.31

Gene sequence:

>483_bases
ATGAGTGCTGACGCCAATCCCGACCTCAAGAGCGCCGATATCGGCTTGATTCAACAGATTCTGCCGCATCGCTATCCGTT
TTTGCTGGTGGACAAGGTGGTCGATATCGACGGCTATCAATCCGCGCGCGGCATCAAGAATGTCACCATGAACGAGCCGC
ATTTTCAGGGCCATTTCCCCGGTACTCCGATCATGCCCGGTGTGACCATCGTCGAAGCGATGGCGCAGACCTCTGGTGTG
ATGCTCGGGGTTGGCATGGATCTGATCGGCACCGATATGCTGATCTATTTCATGAATATCGACAAATGCAAATTCCGCCG
CAAGGTTGTTCCCGGTGATGTGCTGGAAATGCATGTGGAGACGGTGCGCGGCAAACCCGGTGGCAAGATCTTCAAGTTTT
CCGGTCGCGCCACCGTTGATGGCGAACTCGCCGCTGAGGCCGAGTTCACCGCGATGATCGACCGGGACGGAAAGGACGGC
TGA

Upstream 100 bases:

>100_bases
CCTCGATGCCAGCGAACCGGACAGCAATCAGCCCTGAACTTGCCCGAAGGGGCGGCAATTGCTACCACACATATCTGACG
AAACCAATGGAACGTGACCC

Downstream 100 bases:

>100_bases
TGAGCACGATTCACCCCAGCGCCATTATCGAGGATGGCGCCAAAATCGGCGAAGGCTGCGAAATCGGCCCCTTTTGCATC
GTCGGCGCTGAGGTGGTGTT

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MSADANPDLKSADIGLIQQILPHRYPFLLVDKVVDIDGYQSARGIKNVTMNEPHFQGHFPGTPIMPGVTIVEAMAQTSGV
MLGVGMDLIGTDMLIYFMNIDKCKFRRKVVPGDVLEMHVETVRGKPGGKIFKFSGRATVDGELAAEAEFTAMIDRDGKDG

Sequences:

>Translated_160_residues
MSADANPDLKSADIGLIQQILPHRYPFLLVDKVVDIDGYQSARGIKNVTMNEPHFQGHFPGTPIMPGVTIVEAMAQTSGV
MLGVGMDLIGTDMLIYFMNIDKCKFRRKVVPGDVLEMHVETVRGKPGGKIFKFSGRATVDGELAAEAEFTAMIDRDGKDG
>Mature_159_residues
SADANPDLKSADIGLIQQILPHRYPFLLVDKVVDIDGYQSARGIKNVTMNEPHFQGHFPGTPIMPGVTIVEAMAQTSGVM
LGVGMDLIGTDMLIYFMNIDKCKFRRKVVPGDVLEMHVETVRGKPGGKIFKFSGRATVDGELAAEAEFTAMIDRDGKDG

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=147, Percent_Identity=43.5374149659864, Blast_Score=127, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_SILST (Q1GGS8)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613400.1
- ProteinModelPortal:   Q1GGS8
- SMR:   Q1GGS8
- STRING:   Q1GGS8
- GeneID:   4075898
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1405
- NMPDR:   fig|292414.1.peg.3490
- eggNOG:   COG0764
- HOGENOM:   HBG433282
- OMA:   KERRGVA
- PhylomeDB:   Q1GGS8
- ProtClustDB:   PRK00006
- BioCyc:   SSP292414:TM1040_1405-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17440; Mature: 17309

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: ACT_SITE 58-58

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADANPDLKSADIGLIQQILPHRYPFLLVDKVVDIDGYQSARGIKNVTMNEPHFQGHFP
CCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GTPIMPGVTIVEAMAQTSGVMLGVGMDLIGTDMLIYFMNIDKCKFRRKVVPGDVLEMHVE
CCCCCCCHHHHHHHHHHCCEEEECCCCHHHHCEEEEEECCCHHHHHHCCCCCHHHHHHHH
TVRGKPGGKIFKFSGRATVDGELAAEAEFTAMIDRDGKDG
HHCCCCCCEEEEECCCCEECCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
SADANPDLKSADIGLIQQILPHRYPFLLVDKVVDIDGYQSARGIKNVTMNEPHFQGHFP
CCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
GTPIMPGVTIVEAMAQTSGVMLGVGMDLIGTDMLIYFMNIDKCKFRRKVVPGDVLEMHVE
CCCCCCCHHHHHHHHHHCCEEEECCCCHHHHCEEEEEECCCHHHHHHCCCCCHHHHHHHH
TVRGKPGGKIFKFSGRATVDGELAAEAEFTAMIDRDGKDG
HHCCCCCCEEEEECCCCEECCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA