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The map label for this gene is lpxA [H]

Identifier: 99081245

GI number: 99081245

Start: 1497608

End: 1498393

Strand: Reverse

Name: lpxA [H]

Synonym: TM1040_1404

Alternate gene names: 99081245

Gene position: 1498393-1497608 (Counterclockwise)

Preceding gene: 99081246

Following gene: 99081244

Centisome position: 46.81

GC content: 62.6

Gene sequence:

>786_bases
ATGAGCACGATTCACCCCAGCGCCATTATCGAGGATGGCGCCAAAATCGGCGAAGGCTGCGAAATCGGCCCCTTTTGCAT
CGTCGGCGCTGAGGTGGTGTTGGGCGACCGCGTGGTGCTGAAGTCCCATGTGGTCGTGACCGGCGACACGGAGATCGGCG
ATGACACGGTTGTGTTTTCCTTCTCTGTGCTGGGCGAGATCCCGCAGGATCTGAAGTTCAAGGGCGAGAAGTGCCGCACC
GTGATTGGCAAGCGCAACCGCATCCGCGAGCACGTGACCGTGAACGCGGGCACCGAAGGCGGCGGCGGCGTGACCCGGAT
CGGGGATGACGGGCTGTTCATGGCTGGCTGCCACATCGCCCATGACGCGCAGGTGGGCGACCGTGTGATCGTGGTGAATT
CTGCCGCAATTGCAGGGCATTGTGTGCTTGAGGATGACGTGATCATCGGCGGGCTGTCGGGCATCCATCAATGGGTGCGC
ATCGGCCGCGGCGCAATCATCGGCGCTGTCACCATGGTGACGAATGACGTTATTCCCTACGGTCTCGTGCAGGCCTCGCG
CGGCGAATTGGATGGGCTCAATCTTGTGGGCCTGAAACGGCGCGGTGTGAGTCGCGCGGACATCACCGCCCTTCGTGCAG
CCTTTCAGATGCTGGCGCAGGGCGAGGGGACGTTCTCCGAACGCGCCCGCCGCTTGGGCGATGAAAACGACAGCGAATAT
GTGCAGGAAATCGTGGCCTTTATCACCGGTCAGAGCGACCGCCACTTCCTGACTCCCGGCGGCTGA

Upstream 100 bases:

>100_bases
GCAAGATCTTCAAGTTTTCCGGTCGCGCCACCGTTGATGGCGAACTCGCCGCTGAGGCCGAGTTCACCGCGATGATCGAC
CGGGACGGAAAGGACGGCTG

Downstream 100 bases:

>100_bases
GAAAGGTCCGATTATGATTGCACTCATTGCTGGTCGCGGTGCCTTGCCTGCGGAGCTCATCGCACGTCTGCCCGAGCGCC
CAATGGTTTGCGCCATGTCC

Product: UDP-N-acetylglucosamine acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSTIHPSAIIEDGAKIGEGCEIGPFCIVGAEVVLGDRVVLKSHVVVTGDTEIGDDTVVFSFSVLGEIPQDLKFKGEKCRT
VIGKRNRIREHVTVNAGTEGGGGVTRIGDDGLFMAGCHIAHDAQVGDRVIVVNSAAIAGHCVLEDDVIIGGLSGIHQWVR
IGRGAIIGAVTMVTNDVIPYGLVQASRGELDGLNLVGLKRRGVSRADITALRAAFQMLAQGEGTFSERARRLGDENDSEY
VQEIVAFITGQSDRHFLTPGG

Sequences:

>Translated_261_residues
MSTIHPSAIIEDGAKIGEGCEIGPFCIVGAEVVLGDRVVLKSHVVVTGDTEIGDDTVVFSFSVLGEIPQDLKFKGEKCRT
VIGKRNRIREHVTVNAGTEGGGGVTRIGDDGLFMAGCHIAHDAQVGDRVIVVNSAAIAGHCVLEDDVIIGGLSGIHQWVR
IGRGAIIGAVTMVTNDVIPYGLVQASRGELDGLNLVGLKRRGVSRADITALRAAFQMLAQGEGTFSERARRLGDENDSEY
VQEIVAFITGQSDRHFLTPGG
>Mature_260_residues
STIHPSAIIEDGAKIGEGCEIGPFCIVGAEVVLGDRVVLKSHVVVTGDTEIGDDTVVFSFSVLGEIPQDLKFKGEKCRTV
IGKRNRIREHVTVNAGTEGGGGVTRIGDDGLFMAGCHIAHDAQVGDRVIVVNSAAIAGHCVLEDDVIIGGLSGIHQWVRI
GRGAIIGAVTMVTNDVIPYGLVQASRGELDGLNLVGLKRRGVSRADITALRAAFQMLAQGEGTFSERARRLGDENDSEYV
QEIVAFITGQSDRHFLTPGG

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=244, Percent_Identity=46.3114754098361, Blast_Score=223, Evalue=8e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 27585; Mature: 27454

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS00101 HEXAPEP_TRANSFERASES ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIHPSAIIEDGAKIGEGCEIGPFCIVGAEVVLGDRVVLKSHVVVTGDTEIGDDTVVFS
CCCCCCHHHHHCCCCCCCCCCCCCEEEECCEEEECCEEEEEEEEEEECCCCCCCCEEEEE
FSVLGEIPQDLKFKGEKCRTVIGKRNRIREHVTVNAGTEGGGGVTRIGDDGLFMAGCHIA
EHHHHCCCHHHCCCCHHHHHHHHCHHHHHEEEEEECCCCCCCCEEEECCCCEEEECEEEE
HDAQVGDRVIVVNSAAIAGHCVLEDDVIIGGLSGIHQWVRIGRGAIIGAVTMVTNDVIPY
ECCCCCCEEEEEECCEEEEEEEEECCEEEECHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
GLVQASRGELDGLNLVGLKRRGVSRADITALRAAFQMLAQGEGTFSERARRLGDENDSEY
HHEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHH
VQEIVAFITGQSDRHFLTPGG
HHHHHHHHCCCCCCEEECCCC
>Mature Secondary Structure 
STIHPSAIIEDGAKIGEGCEIGPFCIVGAEVVLGDRVVLKSHVVVTGDTEIGDDTVVFS
CCCCCHHHHHCCCCCCCCCCCCCEEEECCEEEECCEEEEEEEEEEECCCCCCCCEEEEE
FSVLGEIPQDLKFKGEKCRTVIGKRNRIREHVTVNAGTEGGGGVTRIGDDGLFMAGCHIA
EHHHHCCCHHHCCCCHHHHHHHHCHHHHHEEEEEECCCCCCCCEEEECCCCEEEECEEEE
HDAQVGDRVIVVNSAAIAGHCVLEDDVIIGGLSGIHQWVRIGRGAIIGAVTMVTNDVIPY
ECCCCCCEEEEEECCEEEEEEEEECCEEEECHHHHHHHHHHCCCHHHHHHHHHHCCCCCH
GLVQASRGELDGLNLVGLKRRGVSRADITALRAAFQMLAQGEGTFSERARRLGDENDSEY
HHEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHH
VQEIVAFITGQSDRHFLTPGG
HHHHHHHHCCCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA