Click here to switch to the map view.

The map label for this gene is ctrA [H]

Identifier: 99081240

GI number: 99081240

Start: 1493148

End: 1493867

Strand: Reverse

Name: ctrA [H]

Synonym: TM1040_1399

Alternate gene names: 99081240

Gene position: 1493867-1493148 (Counterclockwise)

Preceding gene: 99081241

Following gene: 99081239

Centisome position: 46.67

GC content: 54.86

Gene sequence:

>720_bases
ATGCGCATTCTTCTGGTCGAGGATGATCCCACGACAGCGAAAAGCATCGAGCTGATGCTGACTCATGCGAACCTGAACGT
TTATACCACGGATCTTGGCGAAGAGGGCATAGACCTGGCCAAGCTCTATGACTACGACCTGATCCTTCTGGATCTTGGTC
TGCCGGATATGAACGGCCATGAGGTTCTGCGTCAGCTGCGTTTGTCGCGTATCGAGACCCCGATCCTGATCCTCTCCGGT
GCTGATGACACCGAGAACAAGATCAAAGGCTTTGGCTTTGGCGCGGATGACTATCTGACCAAACCCTTCCATCGTGAAGA
GCTGGTCGCCCGGATCCACGCGATCATTCGTCGCTCGAAAGGGCATTCGCAGTCGATCATCAAGACGGGCAAGATCTCGG
TTAACCTTGACGCCAAGACCGTTGATGTCGAAGGGAAATCTGTGCATCTCACTGGTAAGGAATACCAGATGCTCGAGCTG
CTCTCGTTGCGCAAGGGCACAACCCTGACCAAAGAGATGTTCCTGAACCACCTCTATGGCGGAATGGACGAGCCCGAGCT
CAAGATTATCGACGTCTTTATCTGCAAGCTGCGCAAAAAGCTCAGCACAGCAACCGACGGCGAGAACTATATCGAAACCG
TCTGGGGCCGTGGCTATGTGCTGCGAGATCCGCAAGAAGATCTCTCCGCTGGTGGGCCACGCATGGCGGTCGGCGCCTGA

Upstream 100 bases:

>100_bases
GTGATCCTAAAAAATTAACCAACATGGTAACGAGACATTAACCTTTTCGCAGCAAGGTTAACGCAACCTGAGGACAACAG
AGTACAGGCGGAGACCTAAT

Downstream 100 bases:

>100_bases
ACGTCAGACGGGCCATCATAGCCCATTCATTTAAAAACCCCGTCGGGCTGAGCATCCCGGCGGGGTTTTTGCGTCTCTAG
ATCTGACACTGGACCTCTCT

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MRILLVEDDPTTAKSIELMLTHANLNVYTTDLGEEGIDLAKLYDYDLILLDLGLPDMNGHEVLRQLRLSRIETPILILSG
ADDTENKIKGFGFGADDYLTKPFHREELVARIHAIIRRSKGHSQSIIKTGKISVNLDAKTVDVEGKSVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLSTATDGENYIETVWGRGYVLRDPQEDLSAGGPRMAVGA

Sequences:

>Translated_239_residues
MRILLVEDDPTTAKSIELMLTHANLNVYTTDLGEEGIDLAKLYDYDLILLDLGLPDMNGHEVLRQLRLSRIETPILILSG
ADDTENKIKGFGFGADDYLTKPFHREELVARIHAIIRRSKGHSQSIIKTGKISVNLDAKTVDVEGKSVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLSTATDGENYIETVWGRGYVLRDPQEDLSAGGPRMAVGA
>Mature_239_residues
MRILLVEDDPTTAKSIELMLTHANLNVYTTDLGEEGIDLAKLYDYDLILLDLGLPDMNGHEVLRQLRLSRIETPILILSG
ADDTENKIKGFGFGADDYLTKPFHREELVARIHAIIRRSKGHSQSIIKTGKISVNLDAKTVDVEGKSVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLSTATDGENYIETVWGRGYVLRDPQEDLSAGGPRMAVGA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.0869565217391, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=35.1111111111111, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.4841628959276, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=33.9130434782609, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=32.4200913242009, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=30.8370044052863, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=32.5991189427313, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=31.0502283105023, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.8947368421053, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=31.2775330396476, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=29.2792792792793, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=28.5067873303167, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=26.1061946902655, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=26.25, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789149, Length=146, Percent_Identity=31.5068493150685, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=145, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=24.2553191489362, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26740; Mature: 26740

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLVEDDPTTAKSIELMLTHANLNVYTTDLGEEGIDLAKLYDYDLILLDLGLPDMNGH
CEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCEEHHCCCEEEEEECCCCCCCHH
EVLRQLRLSRIETPILILSGADDTENKIKGFGFGADDYLTKPFHREELVARIHAIIRRSK
HHHHHHHHHHCCCCEEEEECCCCCCHHHEECCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GHSQSIIKTGKISVNLDAKTVDVEGKSVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCCCHHEEECEEEEEECCEEEECCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLSTATDGENYIETVWGRGYVLRDPQEDLSAGGPRMAVGA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCHHHHHCCCCEEECCC
>Mature Secondary Structure
MRILLVEDDPTTAKSIELMLTHANLNVYTTDLGEEGIDLAKLYDYDLILLDLGLPDMNGH
CEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCEEHHCCCEEEEEECCCCCCCHH
EVLRQLRLSRIETPILILSGADDTENKIKGFGFGADDYLTKPFHREELVARIHAIIRRSK
HHHHHHHHHHCCCCEEEEECCCCCCHHHEECCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
GHSQSIIKTGKISVNLDAKTVDVEGKSVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCCCHHEEECEEEEEECCEEEECCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLSTATDGENYIETVWGRGYVLRDPQEDLSAGGPRMAVGA
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA