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The map label for this gene is recG [H]

Identifier: 99081238

GI number: 99081238

Start: 1488653

End: 1490743

Strand: Reverse

Name: recG [H]

Synonym: TM1040_1397

Alternate gene names: 99081238

Gene position: 1490743-1488653 (Counterclockwise)

Preceding gene: 99081239

Following gene: 99081235

Centisome position: 46.57

GC content: 61.5

Gene sequence:

>2091_bases
ATGAGCGGTCGCCCAGAACAATTGTTCCCGCTTTTCGCGGAACTTGAGACCTTGCAAGGCGTCGGACCAAAGATTGCCGA
GCATTTTGCGCAGCTGCATATCACGGCCCCCCGCGATCTTCTGTTCTCGCTGCCATACAGCGTTGTTGACCGGCGTAGGC
GCGAAACCATCCGGGGGTTGGATCTGCCGACGACCGCAACGGTCGAAGTCACCGTGGGGCGCCATCGTCCGGCCCGCAAC
CGGGGCGGTGCCTATCGCATCGACGTGACGGACCAGGAGACTGAGTTTCAGCTGGTCTTTTTCCACGGCCGAAGCCGGTA
TCTGACCGCGCAATTGCCGGAAGGCGCGCGGCGTGTGGTTTCGGGCAAGCTTGAGCTATTTGATGGCATGGCTCAGATGG
TCCACCCCGAACACATGCTGCCGCTAGAAGAAGCCGGGGACATTCCGGACTTTGAGCCGGTCTATCATCTGACACACGGC
ATCACCCAAAAAACCATGTACAAGGCCGTCCAGAGCGCCCTTGCGCGGGTGCCGGATCTCACAGAGTGGATGGATCCCGC
GCAAAAAACGAAACAGGGCTGGCCGGATTGGCACGCGGCGATTTCTGCCGCACATGCGCCCGCGACGCTGGAGGATCTAG
GCGCACAGGCCCCGGCGCGCGCGCGCCTTGCCTATGACGAGCTTTTTGCGCACCAGCTTACACTTGCGATTGCCCGCTCG
GTGGAGCGGGACCTGCCGGGACGGCGGTCAGTCGCGACGGGCACGCTGCAGAGAAAGGTGCTTGCCACATTGCCCTATCG
CCCCACCGGGGCGCAGGGGCGAGCCATAGAAGAGATCACCGCCGATATGGGCTCTGAGCGGCGCATGAACCGTTTGCTGC
AAGGCGACGTGGGAGCGGGGAAAACGCTGGTCGGTTTCATGGCGCTTCTGGTTGCGGTCGAGGCTGGCGGTCAGGGTGTG
ATGATGGCGCCGACAGAAATCCTTGCGCGGCAACATCTTGAAGGGCTCAAGCCGCTTGCCGAAGACGCCGGTGTCGTTCT
TGAGATCCTGACCGGACGCGACAAGGGCAAGGACCGTCGCGCCAAACTGGAGTCCCTCGCGCGGGGCGACATCCATATTC
TTGTCGGCACTCATGCGGTGTTCCAGCAAGATGTCGTCTTTGACGATCTGCGCCTCGTGATCGTCGATGAACAGCACCGC
TTTGGCGTGCGGCAACGCATGGAACTGGCTGAAAAAGGCAAGCGCGCGGATGTTCTTGTCATGACCGCGACGCCGATTCC
GCGCTCGCTGGCGTTGACCCAATATGGCGATATGGAGGTCTCGATCCTCGATGAAAAACCGCCAGGACGCAAACCGATCA
AGACTGCGATTCTGAGCACAGAGCGGATGTCCGAGGTTGTGGACCACCTGCGTCGTGCCATCGACGAGGGACGGCAGTGT
TATTGGGTCTGCCCGCTGGTTGAGGAATCCGAGGTGATGGATCTGACCGCTGCGGACGAGCGGTTCAAACACCTGCGCGC
GGTCTTGGGCGAGGAGGTGGTGGGGCTGGTGCATGGCCAAATGCCGCCAGCGGAAAAAGATGCCGCCATGCTCGCGTTTC
AAGAAGGCCGCACCCGTGTTCTGGTGGCGACCACCGTGATCGAGGTCGGGGTCAATGTCCCCAACGCGTCGATCATGGTG
ATCGAACGTGCCGAGATCTTTGGCCTTGCCCAACTGCACCAATTGCGGGGACGGGTGGGGCGCGGCGAGGCGCAGTCCAC
CTGTTTGCTGATGTATCAGCCGCCCCTGACCGAAGGCGGACGCAAGCGGCTCGAGGTGCTGCGCGAGAGCGAAGATGGAT
TTGTCATCGCCGAAACCGATCTGCAAATGCGCGGTGCCGGAGACGTCATCGGCACGGCACAATCTGGTTTGCCACGGTTC
CATATCGCGGATCTCGAGCGTCAGTCGGATCTGATGGCAATCGCGCAAAGCGATGCGCGCGCATTGATGACCTCGGATCC
CGATCTCTCCAGTGCGCGCGGGCGCGCAGCAAGAACGCTCTTGTGGTTGTTGCGTCAGGATGAGGCTATCCGGTTGATTT
CAGTCGGCTAA

Upstream 100 bases:

>100_bases
CCGGGCGCGGGGTCGAAGGCCGCCAAGGCTGCAGAGCTCGGCATTCAGACATTGGATGAGGACGGATGGCTGGACTTGAT
CGGGCAGGCATAGACGCATC

Downstream 100 bases:

>100_bases
TTGGCCTGTGTTCCTATCCTGACAGATTTTTGTTCCAGTTTGTTCGCAAATGTTCTTAGAAAGTTCTTTACACGACTCGC
TTAAAATGAGAACAAAAGGA

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 695

Protein sequence:

>696_residues
MSGRPEQLFPLFAELETLQGVGPKIAEHFAQLHITAPRDLLFSLPYSVVDRRRRETIRGLDLPTTATVEVTVGRHRPARN
RGGAYRIDVTDQETEFQLVFFHGRSRYLTAQLPEGARRVVSGKLELFDGMAQMVHPEHMLPLEEAGDIPDFEPVYHLTHG
ITQKTMYKAVQSALARVPDLTEWMDPAQKTKQGWPDWHAAISAAHAPATLEDLGAQAPARARLAYDELFAHQLTLAIARS
VERDLPGRRSVATGTLQRKVLATLPYRPTGAQGRAIEEITADMGSERRMNRLLQGDVGAGKTLVGFMALLVAVEAGGQGV
MMAPTEILARQHLEGLKPLAEDAGVVLEILTGRDKGKDRRAKLESLARGDIHILVGTHAVFQQDVVFDDLRLVIVDEQHR
FGVRQRMELAEKGKRADVLVMTATPIPRSLALTQYGDMEVSILDEKPPGRKPIKTAILSTERMSEVVDHLRRAIDEGRQC
YWVCPLVEESEVMDLTAADERFKHLRAVLGEEVVGLVHGQMPPAEKDAAMLAFQEGRTRVLVATTVIEVGVNVPNASIMV
IERAEIFGLAQLHQLRGRVGRGEAQSTCLLMYQPPLTEGGRKRLEVLRESEDGFVIAETDLQMRGAGDVIGTAQSGLPRF
HIADLERQSDLMAIAQSDARALMTSDPDLSSARGRAARTLLWLLRQDEAIRLISVG

Sequences:

>Translated_696_residues
MSGRPEQLFPLFAELETLQGVGPKIAEHFAQLHITAPRDLLFSLPYSVVDRRRRETIRGLDLPTTATVEVTVGRHRPARN
RGGAYRIDVTDQETEFQLVFFHGRSRYLTAQLPEGARRVVSGKLELFDGMAQMVHPEHMLPLEEAGDIPDFEPVYHLTHG
ITQKTMYKAVQSALARVPDLTEWMDPAQKTKQGWPDWHAAISAAHAPATLEDLGAQAPARARLAYDELFAHQLTLAIARS
VERDLPGRRSVATGTLQRKVLATLPYRPTGAQGRAIEEITADMGSERRMNRLLQGDVGAGKTLVGFMALLVAVEAGGQGV
MMAPTEILARQHLEGLKPLAEDAGVVLEILTGRDKGKDRRAKLESLARGDIHILVGTHAVFQQDVVFDDLRLVIVDEQHR
FGVRQRMELAEKGKRADVLVMTATPIPRSLALTQYGDMEVSILDEKPPGRKPIKTAILSTERMSEVVDHLRRAIDEGRQC
YWVCPLVEESEVMDLTAADERFKHLRAVLGEEVVGLVHGQMPPAEKDAAMLAFQEGRTRVLVATTVIEVGVNVPNASIMV
IERAEIFGLAQLHQLRGRVGRGEAQSTCLLMYQPPLTEGGRKRLEVLRESEDGFVIAETDLQMRGAGDVIGTAQSGLPRF
HIADLERQSDLMAIAQSDARALMTSDPDLSSARGRAARTLLWLLRQDEAIRLISVG
>Mature_695_residues
SGRPEQLFPLFAELETLQGVGPKIAEHFAQLHITAPRDLLFSLPYSVVDRRRRETIRGLDLPTTATVEVTVGRHRPARNR
GGAYRIDVTDQETEFQLVFFHGRSRYLTAQLPEGARRVVSGKLELFDGMAQMVHPEHMLPLEEAGDIPDFEPVYHLTHGI
TQKTMYKAVQSALARVPDLTEWMDPAQKTKQGWPDWHAAISAAHAPATLEDLGAQAPARARLAYDELFAHQLTLAIARSV
ERDLPGRRSVATGTLQRKVLATLPYRPTGAQGRAIEEITADMGSERRMNRLLQGDVGAGKTLVGFMALLVAVEAGGQGVM
MAPTEILARQHLEGLKPLAEDAGVVLEILTGRDKGKDRRAKLESLARGDIHILVGTHAVFQQDVVFDDLRLVIVDEQHRF
GVRQRMELAEKGKRADVLVMTATPIPRSLALTQYGDMEVSILDEKPPGRKPIKTAILSTERMSEVVDHLRRAIDEGRQCY
WVCPLVEESEVMDLTAADERFKHLRAVLGEEVVGLVHGQMPPAEKDAAMLAFQEGRTRVLVATTVIEVGVNVPNASIMVI
ERAEIFGLAQLHQLRGRVGRGEAQSTCLLMYQPPLTEGGRKRLEVLRESEDGFVIAETDLQMRGAGDVIGTAQSGLPRFH
IADLERQSDLMAIAQSDARALMTSDPDLSSARGRAARTLLWLLRQDEAIRLISVG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=675, Percent_Identity=41.7777777777778, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1787357, Length=379, Percent_Identity=38.7862796833773, Blast_Score=248, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 76917; Mature: 76785

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRPEQLFPLFAELETLQGVGPKIAEHFAQLHITAPRDLLFSLPYSVVDRRRRETIRGL
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCHHHHHHCCHHHHHHHHHHHHCCC
DLPTTATVEVTVGRHRPARNRGGAYRIDVTDQETEFQLVFFHGRSRYLTAQLPEGARRVV
CCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCEEEEEECCHHHHHHH
SGKLELFDGMAQMVHPEHMLPLEEAGDIPDFEPVYHLTHGITQKTMYKAVQSALARVPDL
HHHHHHHHHHHHHCCCHHCCCHHHCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCH
TEWMDPAQKTKQGWPDWHAAISAAHAPATLEDLGAQAPARARLAYDELFAHQLTLAIARS
HHHCCHHHHHHCCCCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VERDLPGRRSVATGTLQRKVLATLPYRPTGAQGRAIEEITADMGSERRMNRLLQGDVGAG
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCC
KTLVGFMALLVAVEAGGQGVMMAPTEILARQHLEGLKPLAEDAGVVLEILTGRDKGKDRR
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHH
AKLESLARGDIHILVGTHAVFQQDVVFDDLRLVIVDEQHRFGVRQRMELAEKGKRADVLV
HHHHHHCCCCEEEEECCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEE
MTATPIPRSLALTQYGDMEVSILDEKPPGRKPIKTAILSTERMSEVVDHLRRAIDEGRQC
EECCCCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YWVCPLVEESEVMDLTAADERFKHLRAVLGEEVVGLVHGQMPPAEKDAAMLAFQEGRTRV
EEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCEE
LVATTVIEVGVNVPNASIMVIERAEIFGLAQLHQLRGRVGRGEAQSTCLLMYQPPLTEGG
EEEEEEEHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCH
RKRLEVLRESEDGFVIAETDLQMRGAGDVIGTAQSGLPRFHIADLERQSDLMAIAQSDAR
HHHHHHHHCCCCCEEEEECCEEECCCCCEEECHHCCCCCEEECCCHHHHHHHHHHHCCCC
ALMTSDPDLSSARGRAARTLLWLLRQDEAIRLISVG
EEECCCCCCCHHCCHHHHHHHHHHCCCCCEEEEECC
>Mature Secondary Structure 
SGRPEQLFPLFAELETLQGVGPKIAEHFAQLHITAPRDLLFSLPYSVVDRRRRETIRGL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHEEECCCHHHHHHCCHHHHHHHHHHHHCCC
DLPTTATVEVTVGRHRPARNRGGAYRIDVTDQETEFQLVFFHGRSRYLTAQLPEGARRVV
CCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCEEEEEECCHHHHHHH
SGKLELFDGMAQMVHPEHMLPLEEAGDIPDFEPVYHLTHGITQKTMYKAVQSALARVPDL
HHHHHHHHHHHHHCCCHHCCCHHHCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCH
TEWMDPAQKTKQGWPDWHAAISAAHAPATLEDLGAQAPARARLAYDELFAHQLTLAIARS
HHHCCHHHHHHCCCCHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VERDLPGRRSVATGTLQRKVLATLPYRPTGAQGRAIEEITADMGSERRMNRLLQGDVGAG
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCCC
KTLVGFMALLVAVEAGGQGVMMAPTEILARQHLEGLKPLAEDAGVVLEILTGRDKGKDRR
HHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHCCHHHHCCCEEEEEECCCCCCCHHH
AKLESLARGDIHILVGTHAVFQQDVVFDDLRLVIVDEQHRFGVRQRMELAEKGKRADVLV
HHHHHHCCCCEEEEECCHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCCCEEE
MTATPIPRSLALTQYGDMEVSILDEKPPGRKPIKTAILSTERMSEVVDHLRRAIDEGRQC
EECCCCCCCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
YWVCPLVEESEVMDLTAADERFKHLRAVLGEEVVGLVHGQMPPAEKDAAMLAFQEGRTRV
EEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCCEE
LVATTVIEVGVNVPNASIMVIERAEIFGLAQLHQLRGRVGRGEAQSTCLLMYQPPLTEGG
EEEEEEEHHCCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCH
RKRLEVLRESEDGFVIAETDLQMRGAGDVIGTAQSGLPRFHIADLERQSDLMAIAQSDAR
HHHHHHHHCCCCCEEEEECCEEECCCCCEEECHHCCCCCEEECCCHHHHHHHHHHHCCCC
ALMTSDPDLSSARGRAARTLLWLLRQDEAIRLISVG
EEECCCCCCCHHCCHHHHHHHHHHCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]