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The map label for this gene is 99081215

Identifier: 99081215

GI number: 99081215

Start: 1466516

End: 1468060

Strand: Reverse

Name: 99081215

Synonym: TM1040_1374

Alternate gene names: NA

Gene position: 1468060-1466516 (Counterclockwise)

Preceding gene: 99081225

Following gene: 99081213

Centisome position: 45.86

GC content: 60.26

Gene sequence:

>1545_bases
ATGACGGATGCAGCACCGCGTCGTCGAAGCCGGGGTGGCGGTGGCGCCGCCCGTCGTGCCGAACGCACCAGCGTCAAGAT
CGAGACAGCGAAGTATATCGAGCGCAATATCCCGAACTACGAGGTGCTGACAGAAGAGGCGCTCGAGGTCATCGAGACAA
ACGCCGAGACCATCCTCGAGGAGGTTGGCGTCAATTTCGTGGATAACCCGGCCGCGCTTGAACGCTGGCGCGACGCGGGC
GCCGATGTTCAGGGCGAGCGGGTCCGGATCCCGCGTGGTCTGGCGCGCAAACTCTGCGAAACTGCGCCGAGCCAGTTTAC
CCAGCACGCGCGCAACCCCGAGAAATCCGTTGAGATCGGCGGCAAGAACCTCGTGCTCGCGCCGATCTACGGCCCGCCGT
TTGTGCGCGATGCCAATGGTGGCCGGCGCTACGCAACGCTGGAGGATTTCCAGAAGTTCGTGAAGCTCGGCTATATGTCG
AAATGGCTGCATCACTCTGGCGGGACCGTCTGCGAGCCCACCGATGTTCCGGTGAACAAACGCCACCTCGACATGTTGAT
GGCGCATATCGAGCTCTCGGATAAACCCTTCATGGGGTCGGTTACGGAACCGAGCCGTGCGCAGGACACCGTTGATATGT
GCGGCATCCTGTTCGGCAAGGATTTCGTGCAGGAAAATACTGTCACCACCTCGCTGATCAACATCAACTCGCCAATGACG
TTTGACGATGTGATGATGGGCGCGCTTGAGGTTTATGCCAAGAACAACCAGGCCTGCATCATTTCGCCCTTCATCGTGGG
CGGTGCAATGGCTCCGGTCACCATCGCGGGCACATTGACACAGGTCCTGGCAGAAGTTCTGGCCGGTGTGGCCTATAGCC
AGCTGATCCGTCCCGGTGCGCCGGTGATCTTCGGGGCCTTTGTGTCGTCGATCGATATGAACTCCGGTGCGCCGACCTTT
GGCACGCCCGAAGCCTCGATGGTGACCTATGGCGCCGGGCAGCTGGCGCGGCGCCTCAATCTGCCCTTCCGCTCGGCGGG
GTCGTTCTGCGGCTCCAAACTCCCCGATGCGCAGGCGGCCTATGAGACGGCGAACTCGCTCAACATGGGGCTCTTGTCCG
GCGTGAACTTCATGCTGCATTCTTGCGGCTGGCTCGAAGGCGGTCTGGTGGCCGATTTTGAGAAATTCGTGATGGACGCC
GATCAGCTCGGCGTGCTGCATGGACTGGCCAAAGGCATCCAGATGGATGAAAACGGGCAGGGCCTTGATGCGATCCGTGA
GGTTGGCCCGGGAGGTCACTACCTAGGATGTGCCCATACGCAAGCGAACTTCAAAACGGCGTTCTGGAAGTCCAACCTCC
TGGATTACAAGCCTTTTGAGCAGTGGGAAGAAGAAGGCGCGCGCGACACCTACAAACTTGCCTCGGCGCGTGTGGAACAT
CTGCTCGCCACCTACAAACAGCCCGAACTGGATCCCGCGATCCGTGAGGCGCTGATGGCTTACATCGCAGAAAAGAAAGC
CTCGATGCCCGACGCCTTTATGTAA

Upstream 100 bases:

>100_bases
ATGTCGCATTTATGCGAGAATAGCCGTTATCCTTCGGCGCGGCCCAGTCTTGCTCCGATAATCAGAATGCACAGAATTCA
TACTGTCGTGAGGAAGAACA

Downstream 100 bases:

>100_bases
GCGATCCGTGGTATTGAGTTCAAACGGCGTCCTGCGGGGCGCCGTTTTTTGTTGCGCGTCGGGGCTGCGAGCGCGACGCC
AGATAGAGACGGCTTTCGGC

Product: trimethylamine methyltransferase

Products: NA

Alternate protein names: TMA methyltransferase [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MTDAAPRRRSRGGGGAARRAERTSVKIETAKYIERNIPNYEVLTEEALEVIETNAETILEEVGVNFVDNPAALERWRDAG
ADVQGERVRIPRGLARKLCETAPSQFTQHARNPEKSVEIGGKNLVLAPIYGPPFVRDANGGRRYATLEDFQKFVKLGYMS
KWLHHSGGTVCEPTDVPVNKRHLDMLMAHIELSDKPFMGSVTEPSRAQDTVDMCGILFGKDFVQENTVTTSLININSPMT
FDDVMMGALEVYAKNNQACIISPFIVGGAMAPVTIAGTLTQVLAEVLAGVAYSQLIRPGAPVIFGAFVSSIDMNSGAPTF
GTPEASMVTYGAGQLARRLNLPFRSAGSFCGSKLPDAQAAYETANSLNMGLLSGVNFMLHSCGWLEGGLVADFEKFVMDA
DQLGVLHGLAKGIQMDENGQGLDAIREVGPGGHYLGCAHTQANFKTAFWKSNLLDYKPFEQWEEEGARDTYKLASARVEH
LLATYKQPELDPAIREALMAYIAEKKASMPDAFM

Sequences:

>Translated_514_residues
MTDAAPRRRSRGGGGAARRAERTSVKIETAKYIERNIPNYEVLTEEALEVIETNAETILEEVGVNFVDNPAALERWRDAG
ADVQGERVRIPRGLARKLCETAPSQFTQHARNPEKSVEIGGKNLVLAPIYGPPFVRDANGGRRYATLEDFQKFVKLGYMS
KWLHHSGGTVCEPTDVPVNKRHLDMLMAHIELSDKPFMGSVTEPSRAQDTVDMCGILFGKDFVQENTVTTSLININSPMT
FDDVMMGALEVYAKNNQACIISPFIVGGAMAPVTIAGTLTQVLAEVLAGVAYSQLIRPGAPVIFGAFVSSIDMNSGAPTF
GTPEASMVTYGAGQLARRLNLPFRSAGSFCGSKLPDAQAAYETANSLNMGLLSGVNFMLHSCGWLEGGLVADFEKFVMDA
DQLGVLHGLAKGIQMDENGQGLDAIREVGPGGHYLGCAHTQANFKTAFWKSNLLDYKPFEQWEEEGARDTYKLASARVEH
LLATYKQPELDPAIREALMAYIAEKKASMPDAFM
>Mature_513_residues
TDAAPRRRSRGGGGAARRAERTSVKIETAKYIERNIPNYEVLTEEALEVIETNAETILEEVGVNFVDNPAALERWRDAGA
DVQGERVRIPRGLARKLCETAPSQFTQHARNPEKSVEIGGKNLVLAPIYGPPFVRDANGGRRYATLEDFQKFVKLGYMSK
WLHHSGGTVCEPTDVPVNKRHLDMLMAHIELSDKPFMGSVTEPSRAQDTVDMCGILFGKDFVQENTVTTSLININSPMTF
DDVMMGALEVYAKNNQACIISPFIVGGAMAPVTIAGTLTQVLAEVLAGVAYSQLIRPGAPVIFGAFVSSIDMNSGAPTFG
TPEASMVTYGAGQLARRLNLPFRSAGSFCGSKLPDAQAAYETANSLNMGLLSGVNFMLHSCGWLEGGLVADFEKFVMDAD
QLGVLHGLAKGIQMDENGQGLDAIREVGPGGHYLGCAHTQANFKTAFWKSNLLDYKPFEQWEEEGARDTYKLASARVEHL
LATYKQPELDPAIREALMAYIAEKKASMPDAFM

Specific function: Catalyzes probably the transfer of a methyl group from trimethylamine to the corrinoid cofactor of mttC [H]

COG id: COG5598

COG function: function code H; Trimethylamine:corrinoid methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trimethylamine methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010426 [H]

Pfam domain/function: PF06253 MTTB [H]

EC number: NA

Molecular weight: Translated: 55982; Mature: 55851

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDAAPRRRSRGGGGAARRAERTSVKIETAKYIERNIPNYEVLTEEALEVIETNAETILE
CCCCCCCHHCCCCCHHHHHHHHCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHH
EVGVNFVDNPAALERWRDAGADVQGERVRIPRGLARKLCETAPSQFTQHARNPEKSVEIG
HHCCCCCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHEEEC
GKNLVLAPIYGPPFVRDANGGRRYATLEDFQKFVKLGYMSKWLHHSGGTVCEPTDVPVNK
CCCEEEEECCCCCCEECCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCH
RHLDMLMAHIELSDKPFMGSVTEPSRAQDTVDMCGILFGKDFVQENTVTTSLININSPMT
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
FDDVMMGALEVYAKNNQACIISPFIVGGAMAPVTIAGTLTQVLAEVLAGVAYSQLIRPGA
HHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVIFGAFVSSIDMNSGAPTFGTPEASMVTYGAGQLARRLNLPFRSAGSFCGSKLPDAQAA
CHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
YETANSLNMGLLSGVNFMLHSCGWLEGGLVADFEKFVMDADQLGVLHGLAKGIQMDENGQ
HHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCC
GLDAIREVGPGGHYLGCAHTQANFKTAFWKSNLLDYKPFEQWEEEGARDTYKLASARVEH
CHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
LLATYKQPELDPAIREALMAYIAEKKASMPDAFM
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TDAAPRRRSRGGGGAARRAERTSVKIETAKYIERNIPNYEVLTEEALEVIETNAETILE
CCCCCCHHCCCCCHHHHHHHHCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHH
EVGVNFVDNPAALERWRDAGADVQGERVRIPRGLARKLCETAPSQFTQHARNPEKSVEIG
HHCCCCCCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHEEEC
GKNLVLAPIYGPPFVRDANGGRRYATLEDFQKFVKLGYMSKWLHHSGGTVCEPTDVPVNK
CCCEEEEECCCCCCEECCCCCCEECCHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCH
RHLDMLMAHIELSDKPFMGSVTEPSRAQDTVDMCGILFGKDFVQENTVTTSLININSPMT
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCC
FDDVMMGALEVYAKNNQACIISPFIVGGAMAPVTIAGTLTQVLAEVLAGVAYSQLIRPGA
HHHHHHHHHHHHCCCCCEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PVIFGAFVSSIDMNSGAPTFGTPEASMVTYGAGQLARRLNLPFRSAGSFCGSKLPDAQAA
CHHHHHHHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
YETANSLNMGLLSGVNFMLHSCGWLEGGLVADFEKFVMDADQLGVLHGLAKGIQMDENGQ
HHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCC
GLDAIREVGPGGHYLGCAHTQANFKTAFWKSNLLDYKPFEQWEEEGARDTYKLASARVEH
CHHHHHHCCCCCCEEEEECCCCCCHHHHHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
LLATYKQPELDPAIREALMAYIAEKKASMPDAFM
HHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA