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The map label for this gene is trkG [H]

Identifier: 99081198

GI number: 99081198

Start: 1448429

End: 1449967

Strand: Reverse

Name: trkG [H]

Synonym: TM1040_1357

Alternate gene names: 99081198

Gene position: 1449967-1448429 (Counterclockwise)

Preceding gene: 99081199

Following gene: 99081197

Centisome position: 45.3

GC content: 59.71

Gene sequence:

>1539_bases
ATGATACGCCGCCCCCTGAAACAAGTGCGCGGTGTGCTGCGCTTGCCGCTGCTGCTGCTCATCTGGGGGGTGTTTGCCAT
TGCGATGTGGATCCCGGCCGTACATGCGGTGATTGTGGATGACCACCAGACATCGCAGAGCTTCTTTTATTCCGGGATTG
TCGGGCTCACGTTGGTGGCCTTTGTGGGGCTTTCGGTTTCGAACCGCGTGCCGCGTTACGGGATGCCAGGGCAGCTTATG
ACCCTGCTCGCGACTTTTGTGCTTTTGCCGCTCTACCTCGCCATTCCGCTGCAGGATGCGTTGAAAAACACAAGCTATCT
CAATGCCTATTTCGATATGGTCTCGGCGCTAACGACCACGGGGGCCGATATTTTTGACCGTCCTGGACGGGTGCCGGACT
CGGTGCACCTGTGGCGGGTTCTGGTGGCGTGGCTTGGCGGCATGTTCATGTGGATTGCGGCCTCAGCCGTGCTGGCGCCT
CTGTCGCTCGGCGGGTTTGAGGTCACCACGCGCGCAGAACCCGGTCGCAGCGATGCAATCCTGCGCGAAAGCCAGCGCCC
CGACCCGCGGCGTAAGCTGATCATCGTGACCCGTGCGCTTGCGCCGGTTTATGCGGGCCTGACCTTTGCGCTGGCTCTTT
TGCTCATGCTGTGTGGCGAGAGCGGCCTTGTCGCCGTCAGCCATGCCATGTCGATCATGGCGACCTCCGGTCTGTCGCCG
ATTGGCGGCATTCAGGATGCACAGGCGGGCCTCGCTGGCGAGATGATCATGTTCCTTTTTCTGCTGTTTGCGCTCTCACG
CCTGACGTTTTCCAGCGATACAGTGGCTGTGGGGCATGGGCGTCTCGACAAGGATCCCGAGTTCCGCTCTGGCATTCTCA
TCATTCTCGGCGTGCCGATGCTCTTGTTTCTGCGGCATTGGCTAGCCTCGCTCGAGGTGAATGCGTCTGACGATTGGGGC
ATGGCGCTGACCTCTCTTTGGGGTGCGATTTTCACCGTTGCCTCATTCCTCACAACCAACGGATTTGAGAGCGCGTATTG
GTTCAGCGCGCAGGAATGGTCGGGACTGGAGACACCGGGTATGATCCTGCTCGGGCTGGCGGTCATGGGCGGTGGCGTTG
CGACCACTGCAGGCGGCGTAAAGCTCCTGCGTGTCTATGCGCTATATCTCAATGGTCTTCGGGAAATGGAGCGTCTGGTC
CTACCGTCCTCCGTCAGTGGTGAGGGGCGGGGCAATCGACGCCTGCAGAGCAATGGTGCCTTTGTGGCCTGGATCTTTTT
CATGCTCTTTGCGCTGTCCTTGACGCTCATTTCGGTGGCGCTCTCGGCCTTTGGTATTCCGTTTGAACAGGCTATGATTC
TCGCCGTTGCGGGGCTTTCCACAACGGGGCCTTTGGTGGAGGCCGCAGGGCAGGTTCCCATCGAGCTCAATCTGCTGGAT
GCCCCCGCAAAGCTGATCTTGTGTTTTGCGATGGTTCTGGGGCGTCTGGAAACGCTGGCCATTATCGCGCTTCTGTCGCC
CAATCTTTGGCGCAACTGA

Upstream 100 bases:

>100_bases
CTTCGGATCGAGGCGGGGGACACGATTGCCCTCTTTGCGATGGCCGCTGATGTGCGGGAGGTCGAGCGCCTGATGCAAGT
CTCGATCGACTACTTCTAGG

Downstream 100 bases:

>100_bases
CACATACTGGCTAAGTCATGCGAAAAAGTGACGTTTTTCGGGTGGAAACCCGCGAAATCTGCGTCCATACTCGCCATAAG
GGACGCGTTGGGCCGCAGCG

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MIRRPLKQVRGVLRLPLLLLIWGVFAIAMWIPAVHAVIVDDHQTSQSFFYSGIVGLTLVAFVGLSVSNRVPRYGMPGQLM
TLLATFVLLPLYLAIPLQDALKNTSYLNAYFDMVSALTTTGADIFDRPGRVPDSVHLWRVLVAWLGGMFMWIAASAVLAP
LSLGGFEVTTRAEPGRSDAILRESQRPDPRRKLIIVTRALAPVYAGLTFALALLLMLCGESGLVAVSHAMSIMATSGLSP
IGGIQDAQAGLAGEMIMFLFLLFALSRLTFSSDTVAVGHGRLDKDPEFRSGILIILGVPMLLFLRHWLASLEVNASDDWG
MALTSLWGAIFTVASFLTTNGFESAYWFSAQEWSGLETPGMILLGLAVMGGGVATTAGGVKLLRVYALYLNGLREMERLV
LPSSVSGEGRGNRRLQSNGAFVAWIFFMLFALSLTLISVALSAFGIPFEQAMILAVAGLSTTGPLVEAAGQVPIELNLLD
APAKLILCFAMVLGRLETLAIIALLSPNLWRN

Sequences:

>Translated_512_residues
MIRRPLKQVRGVLRLPLLLLIWGVFAIAMWIPAVHAVIVDDHQTSQSFFYSGIVGLTLVAFVGLSVSNRVPRYGMPGQLM
TLLATFVLLPLYLAIPLQDALKNTSYLNAYFDMVSALTTTGADIFDRPGRVPDSVHLWRVLVAWLGGMFMWIAASAVLAP
LSLGGFEVTTRAEPGRSDAILRESQRPDPRRKLIIVTRALAPVYAGLTFALALLLMLCGESGLVAVSHAMSIMATSGLSP
IGGIQDAQAGLAGEMIMFLFLLFALSRLTFSSDTVAVGHGRLDKDPEFRSGILIILGVPMLLFLRHWLASLEVNASDDWG
MALTSLWGAIFTVASFLTTNGFESAYWFSAQEWSGLETPGMILLGLAVMGGGVATTAGGVKLLRVYALYLNGLREMERLV
LPSSVSGEGRGNRRLQSNGAFVAWIFFMLFALSLTLISVALSAFGIPFEQAMILAVAGLSTTGPLVEAAGQVPIELNLLD
APAKLILCFAMVLGRLETLAIIALLSPNLWRN
>Mature_512_residues
MIRRPLKQVRGVLRLPLLLLIWGVFAIAMWIPAVHAVIVDDHQTSQSFFYSGIVGLTLVAFVGLSVSNRVPRYGMPGQLM
TLLATFVLLPLYLAIPLQDALKNTSYLNAYFDMVSALTTTGADIFDRPGRVPDSVHLWRVLVAWLGGMFMWIAASAVLAP
LSLGGFEVTTRAEPGRSDAILRESQRPDPRRKLIIVTRALAPVYAGLTFALALLLMLCGESGLVAVSHAMSIMATSGLSP
IGGIQDAQAGLAGEMIMFLFLLFALSRLTFSSDTVAVGHGRLDKDPEFRSGILIILGVPMLLFLRHWLASLEVNASDDWG
MALTSLWGAIFTVASFLTTNGFESAYWFSAQEWSGLETPGMILLGLAVMGGGVATTAGGVKLLRVYALYLNGLREMERLV
LPSSVSGEGRGNRRLQSNGAFVAWIFFMLFALSLTLISVALSAFGIPFEQAMILAVAGLSTTGPLVEAAGQVPIELNLLD
APAKLILCFAMVLGRLETLAIIALLSPNLWRN

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=433, Percent_Identity=26.7898383371824, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI48994987, Length=419, Percent_Identity=29.8329355608592, Blast_Score=106, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 55213; Mature: 55213

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRPLKQVRGVLRLPLLLLIWGVFAIAMWIPAVHAVIVDDHQTSQSFFYSGIVGLTLVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
FVGLSVSNRVPRYGMPGQLMTLLATFVLLPLYLAIPLQDALKNTSYLNAYFDMVSALTTT
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHC
GADIFDRPGRVPDSVHLWRVLVAWLGGMFMWIAASAVLAPLSLGGFEVTTRAEPGRSDAI
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
LRESQRPDPRRKLIIVTRALAPVYAGLTFALALLLMLCGESGLVAVSHAMSIMATSGLSP
HHHCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
IGGIQDAQAGLAGEMIMFLFLLFALSRLTFSSDTVAVGHGRLDKDPEFRSGILIILGVPM
CCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHCCEEHHHHHHH
LLFLRHWLASLEVNASDDWGMALTSLWGAIFTVASFLTTNGFESAYWFSAQEWSGLETPG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCH
MILLGLAVMGGGVATTAGGVKLLRVYALYLNGLREMERLVLPSSVSGEGRGNRRLQSNGA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCC
FVAWIFFMLFALSLTLISVALSAFGIPFEQAMILAVAGLSTTGPLVEAAGQVPIELNLLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECC
APAKLILCFAMVLGRLETLAIIALLSPNLWRN
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIRRPLKQVRGVLRLPLLLLIWGVFAIAMWIPAVHAVIVDDHQTSQSFFYSGIVGLTLVA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHH
FVGLSVSNRVPRYGMPGQLMTLLATFVLLPLYLAIPLQDALKNTSYLNAYFDMVSALTTT
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHHHHC
GADIFDRPGRVPDSVHLWRVLVAWLGGMFMWIAASAVLAPLSLGGFEVTTRAEPGRSDAI
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHH
LRESQRPDPRRKLIIVTRALAPVYAGLTFALALLLMLCGESGLVAVSHAMSIMATSGLSP
HHHCCCCCCHHEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
IGGIQDAQAGLAGEMIMFLFLLFALSRLTFSSDTVAVGHGRLDKDPEFRSGILIILGVPM
CCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCHHCCEEHHHHHHH
LLFLRHWLASLEVNASDDWGMALTSLWGAIFTVASFLTTNGFESAYWFSAQEWSGLETPG
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCH
MILLGLAVMGGGVATTAGGVKLLRVYALYLNGLREMERLVLPSSVSGEGRGNRRLQSNGA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCC
FVAWIFFMLFALSLTLISVALSAFGIPFEQAMILAVAGLSTTGPLVEAAGQVPIELNLLD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEECC
APAKLILCFAMVLGRLETLAIIALLSPNLWRN
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]