Click here to switch to the map view.

The map label for this gene is trkA [H]

Identifier: 99081199

GI number: 99081199

Start: 1449969

End: 1451345

Strand: Reverse

Name: trkA [H]

Synonym: TM1040_1358

Alternate gene names: 99081199

Gene position: 1451345-1449969 (Counterclockwise)

Preceding gene: 99081200

Following gene: 99081198

Centisome position: 45.34

GC content: 60.57

Gene sequence:

>1377_bases
ATGAAAGTTATCATCTGTGGAGCCGGGCAGGTCGGTTGGCAGATCGCACGGCATTTGTCCGGCGAACACAACGACGTGAC
GGTTGTCGACAACAATCCTGACCTTGTGCGCCGCGCGACAGATACGCTTGATGTTCAAGGCATTGCGGGCTTTGCCTCAT
ATCCGGATGTTCTTGATCGGGCCGGGGCGCGGGACGCGGATATGATCATCGCCGCCACGCACTCGGACGAGGTGAACATG
GTCACCTGCCAAGTGGCGCATTCCGTGTTTGCCATCCAGCGCAAGATCGCGCGTCTGCGGGCCAAGAGCTATCTGAACGC
GATTTATTCCGATCTCTATCGCCGGGACCATCTGCCGATCGATGTGGTGATCAGCCCGGAGCGGGAAGTTGCGGCGGCGG
CTATGCAGCGTCTGCGCGCGCCGGCAGCTTTTGACACCGAAGTATTCATGGACGGACGTGCGCAGCTGTTGGGCATCAAC
GTGGAGGCAGACTGCCCCGTTGTAAACACGCCGCTGCGCCAGTTGACGGAGCTCTTCTCGACGTTGCGTGCCATTGTGGT
TGGCATTCGCCGCGACGGATCGCTGTTTGCGCCGGAGCCAGGGGATCAACTGTTTGTGGGCGATGCGGCCTATGTGTTTT
GCCATGCAGACGACGTGAGCCGCACGATGGAAGTCTTTGGAAAGACTGAGAAACGTCAGGAGCGCGTGGTGATCGTCGGC
GGCGGCAATGTCGGCCTTGAAGTTGCCAAAGCGCTCGAGGCGCGCACCCGGCGCACGCGGGCCAAGATGATCGAAAAGAA
CCGCAAAAACGCCGAGGTTGCCGCAGAGGCTCTGGAACGCACGATCGTTCTGAATGGCGATGGTCTGGATCGGGGGCTGA
TGATCGAGGCGGGCATCGACAAGGCCGATGCCATGCTGGCGGTGACCGATGACGACAAGACCAACATGCTGGCAGCGGTG
CGTGCCAAGACCGAAGGCTGCCCGTTTGCAATCGCCCTGATCAACGACCCGACGCTGCTGCCGCTGCTGCCGCACCTCGG
GATTGACGCGCATATCAATCCGCGCGCCACCACCGTCAGTTCTATCCTGCGTCACATCCGCTATGGCCGTATCCGGCAGG
TTTATTCCATTGGCGACGCCGAAGCGGAAGTTATTGAAACCGAAGTGCTTTCTACCTCTCCCATGGCGGGGCAGGCCATT
CGGGACATTGATTTCCCCGAAGGTGTGCTGGTGGGCGCTGTATCCAAGAACGGCGAGGTCATGCGCCCCAGTGGCGGGCT
TCGGATCGAGGCGGGGGACACGATTGCCCTCTTTGCGATGGCCGCTGATGTGCGGGAGGTCGAGCGCCTGATGCAAGTCT
CGATCGACTACTTCTAG

Upstream 100 bases:

>100_bases
AATCAGGTGTAGGCCAGGGCTGCGGCGGGACAATTGAATTGACCCCCTTCGCACCATCTGGCATGCAAATCAGGCAGTCC
AGCGCCCGGAGAGCGGATCT

Downstream 100 bases:

>100_bases
GATGATACGCCGCCCCCTGAAACAAGTGCGCGGTGTGCTGCGCTTGCCGCTGCTGCTGCTCATCTGGGGGGTGTTTGCCA
TTGCGATGTGGATCCCGGCC

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MKVIICGAGQVGWQIARHLSGEHNDVTVVDNNPDLVRRATDTLDVQGIAGFASYPDVLDRAGARDADMIIAATHSDEVNM
VTCQVAHSVFAIQRKIARLRAKSYLNAIYSDLYRRDHLPIDVVISPEREVAAAAMQRLRAPAAFDTEVFMDGRAQLLGIN
VEADCPVVNTPLRQLTELFSTLRAIVVGIRRDGSLFAPEPGDQLFVGDAAYVFCHADDVSRTMEVFGKTEKRQERVVIVG
GGNVGLEVAKALEARTRRTRAKMIEKNRKNAEVAAEALERTIVLNGDGLDRGLMIEAGIDKADAMLAVTDDDKTNMLAAV
RAKTEGCPFAIALINDPTLLPLLPHLGIDAHINPRATTVSSILRHIRYGRIRQVYSIGDAEAEVIETEVLSTSPMAGQAI
RDIDFPEGVLVGAVSKNGEVMRPSGGLRIEAGDTIALFAMAADVREVERLMQVSIDYF

Sequences:

>Translated_458_residues
MKVIICGAGQVGWQIARHLSGEHNDVTVVDNNPDLVRRATDTLDVQGIAGFASYPDVLDRAGARDADMIIAATHSDEVNM
VTCQVAHSVFAIQRKIARLRAKSYLNAIYSDLYRRDHLPIDVVISPEREVAAAAMQRLRAPAAFDTEVFMDGRAQLLGIN
VEADCPVVNTPLRQLTELFSTLRAIVVGIRRDGSLFAPEPGDQLFVGDAAYVFCHADDVSRTMEVFGKTEKRQERVVIVG
GGNVGLEVAKALEARTRRTRAKMIEKNRKNAEVAAEALERTIVLNGDGLDRGLMIEAGIDKADAMLAVTDDDKTNMLAAV
RAKTEGCPFAIALINDPTLLPLLPHLGIDAHINPRATTVSSILRHIRYGRIRQVYSIGDAEAEVIETEVLSTSPMAGQAI
RDIDFPEGVLVGAVSKNGEVMRPSGGLRIEAGDTIALFAMAADVREVERLMQVSIDYF
>Mature_458_residues
MKVIICGAGQVGWQIARHLSGEHNDVTVVDNNPDLVRRATDTLDVQGIAGFASYPDVLDRAGARDADMIIAATHSDEVNM
VTCQVAHSVFAIQRKIARLRAKSYLNAIYSDLYRRDHLPIDVVISPEREVAAAAMQRLRAPAAFDTEVFMDGRAQLLGIN
VEADCPVVNTPLRQLTELFSTLRAIVVGIRRDGSLFAPEPGDQLFVGDAAYVFCHADDVSRTMEVFGKTEKRQERVVIVG
GGNVGLEVAKALEARTRRTRAKMIEKNRKNAEVAAEALERTIVLNGDGLDRGLMIEAGIDKADAMLAVTDDDKTNMLAAV
RAKTEGCPFAIALINDPTLLPLLPHLGIDAHINPRATTVSSILRHIRYGRIRQVYSIGDAEAEVIETEVLSTSPMAGQAI
RDIDFPEGVLVGAVSKNGEVMRPSGGLRIEAGDTIALFAMAADVREVERLMQVSIDYF

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=458, Percent_Identity=36.0262008733624, Blast_Score=266, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49835; Mature: 49835

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIICGAGQVGWQIARHLSGEHNDVTVVDNNPDLVRRATDTLDVQGIAGFASYPDVLDR
CEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCEECCCCCCCCCHHHHHH
AGARDADMIIAATHSDEVNMVTCQVAHSVFAIQRKIARLRAKSYLNAIYSDLYRRDHLPI
CCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
DVVISPEREVAAAAMQRLRAPAAFDTEVFMDGRAQLLGINVEADCPVVNTPLRQLTELFS
EEEECCCHHHHHHHHHHHCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHH
TLRAIVVGIRRDGSLFAPEPGDQLFVGDAAYVFCHADDVSRTMEVFGKTEKRQERVVIVG
HHHHHHEEECCCCCEECCCCCCEEEECCEEEEEEECCHHHHHHHHHCCCCCCCCEEEEEE
GGNVGLEVAKALEARTRRTRAKMIEKNRKNAEVAAEALERTIVLNGDGLDRGLMIEAGID
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCCCEEEECCCC
KADAMLAVTDDDKTNMLAAVRAKTEGCPFAIALINDPTLLPLLPHLGIDAHINPRATTVS
CCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHH
SILRHIRYGRIRQVYSIGDAEAEVIETEVLSTSPMAGQAIRDIDFPEGVLVGAVSKNGEV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEECCCCCE
MRPSGGLRIEAGDTIALFAMAADVREVERLMQVSIDYF
ECCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKVIICGAGQVGWQIARHLSGEHNDVTVVDNNPDLVRRATDTLDVQGIAGFASYPDVLDR
CEEEEECCCHHHHHHHHHHCCCCCCEEEEECCCHHHHHHCCCCEECCCCCCCCCHHHHHH
AGARDADMIIAATHSDEVNMVTCQVAHSVFAIQRKIARLRAKSYLNAIYSDLYRRDHLPI
CCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
DVVISPEREVAAAAMQRLRAPAAFDTEVFMDGRAQLLGINVEADCPVVNTPLRQLTELFS
EEEECCCHHHHHHHHHHHCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCCHHHHHHHHH
TLRAIVVGIRRDGSLFAPEPGDQLFVGDAAYVFCHADDVSRTMEVFGKTEKRQERVVIVG
HHHHHHEEECCCCCEECCCCCCEEEECCEEEEEEECCHHHHHHHHHCCCCCCCCEEEEEE
GGNVGLEVAKALEARTRRTRAKMIEKNRKNAEVAAEALERTIVLNGDGLDRGLMIEAGID
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEECCCCCCCEEEECCCC
KADAMLAVTDDDKTNMLAAVRAKTEGCPFAIALINDPTLLPLLPHLGIDAHINPRATTVS
CCCEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCHHHHH
SILRHIRYGRIRQVYSIGDAEAEVIETEVLSTSPMAGQAIRDIDFPEGVLVGAVSKNGEV
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEEEEECCCCCE
MRPSGGLRIEAGDTIALFAMAADVREVERLMQVSIDYF
ECCCCCEEEECCCEEEEEHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]