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The map label for this gene is pgl [H]

Identifier: 99081171

GI number: 99081171

Start: 1416887

End: 1417558

Strand: Reverse

Name: pgl [H]

Synonym: TM1040_1330

Alternate gene names: 99081171

Gene position: 1417558-1416887 (Counterclockwise)

Preceding gene: 99081172

Following gene: 99081165

Centisome position: 44.29

GC content: 61.61

Gene sequence:

>672_bases
ATGTATTTCAACGAATATCCGGATAGAGAGATGCTCTCGATCTCGGTTGCCAATCGGATTGCCGGGGATCTGAAAACCCA
GCTTTTGAACGATGGGCACGCCGCCATCGCCGTCGCTGGCGGCACCACTCCGGGCCCGATATTCGACGACCTCTGCGCTG
CTGAGCTCGATTGGGCCAATGTCTGCGTGATGGCTTCGGACGAGCGTTGGGTTCCAGAGGACAGCGATCGCTCGAACGCA
AAGCTGATCCGCAATCGGCTCTTGACCAACCGTGCGTCCGAGGCCCGGTTCTTGCCGTTTTACAAAACAGGGCTTGAGCC
AAACGACGCGATCGCGCCGCTCTGCGAAGAGGTGCGCGGGCAGGGTGGCCTTGGAGTTGCGCTCTTGGGCATGGGCACGG
ACATGCACACGGCCAGCCTCTTTCCGGGCGTTTCCGGGCTCGAGGCCGCGCTGGCCGCAGACGCGCCAGAGCTTGCCGTA
ATGCGTCCCGATAGCCAACCCGAGCCGCGTATCACGCTGACCGCACGGGTCCTGGACGCCGCTATGGCAAAACACTTGGT
GATTTTTGGTGCGGACAAACGCGAGGCGCTGGAACGCGCGCAAAGCCTGCCGCCAGAAGAAGCGCCGATTCAGGCTGTCC
TGTCTGAATGTGAGGTCCATTGGGCTGCCTGA

Upstream 100 bases:

>100_bases
ATCCGGTTCGATGGCTTGGCCTTTGCGGCAAGCTGTGACACTGTTTTGAACAGACGATTTCATCCTGCGGGATGCGACCT
CAAGTTTCAGGAGCAGTGTC

Downstream 100 bases:

>100_bases
GCCCTCGATGATCTTGCCGCAGGGAGGTGCTCAGCCTGCCTGCGTCGCCCCATCAACGTCGACAAACTGCTGCGTCAGGC
TCTCCGGGATCGGATAGCCG

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MYFNEYPDREMLSISVANRIAGDLKTQLLNDGHAAIAVAGGTTPGPIFDDLCAAELDWANVCVMASDERWVPEDSDRSNA
KLIRNRLLTNRASEARFLPFYKTGLEPNDAIAPLCEEVRGQGGLGVALLGMGTDMHTASLFPGVSGLEAALAADAPELAV
MRPDSQPEPRITLTARVLDAAMAKHLVIFGADKREALERAQSLPPEEAPIQAVLSECEVHWAA

Sequences:

>Translated_223_residues
MYFNEYPDREMLSISVANRIAGDLKTQLLNDGHAAIAVAGGTTPGPIFDDLCAAELDWANVCVMASDERWVPEDSDRSNA
KLIRNRLLTNRASEARFLPFYKTGLEPNDAIAPLCEEVRGQGGLGVALLGMGTDMHTASLFPGVSGLEAALAADAPELAV
MRPDSQPEPRITLTARVLDAAMAKHLVIFGADKREALERAQSLPPEEAPIQAVLSECEVHWAA
>Mature_223_residues
MYFNEYPDREMLSISVANRIAGDLKTQLLNDGHAAIAVAGGTTPGPIFDDLCAAELDWANVCVMASDERWVPEDSDRSNA
KLIRNRLLTNRASEARFLPFYKTGLEPNDAIAPLCEEVRGQGGLGVALLGMGTDMHTASLFPGVSGLEAALAADAPELAV
MRPDSQPEPRITLTARVLDAAMAKHLVIFGADKREALERAQSLPPEEAPIQAVLSECEVHWAA

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI52145310, Length=224, Percent_Identity=28.125, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900 [H]

Pfam domain/function: NA

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 23993; Mature: 23993

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFNEYPDREMLSISVANRIAGDLKTQLLNDGHAAIAVAGGTTPGPIFDDLCAAELDWAN
CCCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCE
VCVMASDERWVPEDSDRSNAKLIRNRLLTNRASEARFLPFYKTGLEPNDAIAPLCEEVRG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHHHHHHCC
QGGLGVALLGMGTDMHTASLFPGVSGLEAALAADAPELAVMRPDSQPEPRITLTARVLDA
CCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHCCCCCEEEECCCCCCCCCEEEHHHHHHH
AMAKHLVIFGADKREALERAQSLPPEEAPIQAVLSECEVHWAA
HHHHEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYFNEYPDREMLSISVANRIAGDLKTQLLNDGHAAIAVAGGTTPGPIFDDLCAAELDWAN
CCCCCCCCCHHEEHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCE
VCVMASDERWVPEDSDRSNAKLIRNRLLTNRASEARFLPFYKTGLEPNDAIAPLCEEVRG
EEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCHHHCCCCCCHHHHHHHHHHCC
QGGLGVALLGMGTDMHTASLFPGVSGLEAALAADAPELAVMRPDSQPEPRITLTARVLDA
CCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHCCCCCEEEECCCCCCCCCEEEHHHHHHH
AMAKHLVIFGADKREALERAQSLPPEEAPIQAVLSECEVHWAA
HHHHEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]