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The map label for this gene is obgE

Identifier: 99081044

GI number: 99081044

Start: 1292795

End: 1293841

Strand: Direct

Name: obgE

Synonym: TM1040_1203

Alternate gene names: 99081044

Gene position: 1292795-1293841 (Clockwise)

Preceding gene: 99081043

Following gene: 99081045

Centisome position: 40.39

GC content: 62.08

Gene sequence:

>1047_bases
ATGAAATTCCTCGATCTGGCAAAGGTCTATATTCGCTCCGGCGCCGGCGGGAACGGTTGCGTCAGTTTTCGGCGCGAAAA
ATTCATCGAATACGGCGGCCCCGATGGCGGTGACGGCGGCAAGGGCGGCTCGGTCTGGGCGGAGGCCGTGGATGGCCTCA
ACACGCTCATCGATTTTCGCTATCAGCAGCATTTCTTTGCCAAAAACGGCCAGTCCGGCATGGGGCGCCAGCGCTCCGGC
AAGGACGGTGACGAGATCGTGCTGCGGGTGCCTGTGGGCACCGAGATCCTCGATGAGGACGAAGAGACGGTTCTGGCGGA
TCTGACCCATGTGGGCGAACGCGTGCTGCTGGCCAAAGGCGGCAATGGCGGCTTTGGGAACCTGCACTTCAAATCCTCTA
CCAACCAGGCGCCCCGGCGCGCGAATTCCGGTCAGGAGGGTGTCGAACGCACCATCTGGCTGCGCCTGAAGCTGATTGCG
GATGCGGGTCTATTGGGTCTGCCGAATGCGGGCAAATCGACGTTCCTGTCGTCGACCTCCAACGCGCGACCCAAGATCGC
CGACTATCCTTTCACCACATTGCACCCGAATCTCGGGGTGGTGGGCATCGACAATACCGAATTTGTGATGGCGGATATTC
CGGGCCTCATCGAGGGGGCGCACGAAGGCCGTGGCATCGGGGATCGTTTCCTGGGCCATGTGGAGCGTTGCGCTGTGCTG
CTCCACCTGGTTGATGGCACCTCTGAAACGGTGGCCGAGGATTACCGCACCATCATCAACGAACTCGAAGCCTATGGCGG
AGAGCTTGCGAGCAAGCCCCGTGTCACCGCGCTCAACAAGATTGACGCGCTGGATGACGAGGAACGGGCCGAGGCGCGTG
CTGCGCTTGAGGCCGAGGTGGGAGCGCCGGTTCTGATGATGTCGAGCGTGAGCCGGGAAGGTCTGGATCTGGTCCTGCGT
GCGGTGCGCGCCGAGATCGATGATGACCGCCTTCGGATCAAACAGGCGGAGGCGTCCGAGGAGGAGGACACCCCTTGGCA
GCCCTAA

Upstream 100 bases:

>100_bases
TTGGGCATGGAACGGGATCTCCTCAGATCCAAAGACGCAGGGTTGAGCCATCCCCTGAATTCAAGTATTGGCGATCCAAC
TCGAACACAGAGGCCTACTC

Downstream 100 bases:

>100_bases
GCACGGCGCGGCGCGTCGTCATCAAGATCGGCTCCGCCCTTTTGGTGGATCGCACCAGCAGTGCCTTGCGGCAGGAGTGG
CTCCTGTCGCTGGCAGAGGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MKFLDLAKVYIRSGAGGNGCVSFRREKFIEYGGPDGGDGGKGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQSGMGRQRSG
KDGDEIVLRVPVGTEILDEDEETVLADLTHVGERVLLAKGGNGGFGNLHFKSSTNQAPRRANSGQEGVERTIWLRLKLIA
DAGLLGLPNAGKSTFLSSTSNARPKIADYPFTTLHPNLGVVGIDNTEFVMADIPGLIEGAHEGRGIGDRFLGHVERCAVL
LHLVDGTSETVAEDYRTIINELEAYGGELASKPRVTALNKIDALDDEERAEARAALEAEVGAPVLMMSSVSREGLDLVLR
AVRAEIDDDRLRIKQAEASEEEDTPWQP

Sequences:

>Translated_348_residues
MKFLDLAKVYIRSGAGGNGCVSFRREKFIEYGGPDGGDGGKGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQSGMGRQRSG
KDGDEIVLRVPVGTEILDEDEETVLADLTHVGERVLLAKGGNGGFGNLHFKSSTNQAPRRANSGQEGVERTIWLRLKLIA
DAGLLGLPNAGKSTFLSSTSNARPKIADYPFTTLHPNLGVVGIDNTEFVMADIPGLIEGAHEGRGIGDRFLGHVERCAVL
LHLVDGTSETVAEDYRTIINELEAYGGELASKPRVTALNKIDALDDEERAEARAALEAEVGAPVLMMSSVSREGLDLVLR
AVRAEIDDDRLRIKQAEASEEEDTPWQP
>Mature_348_residues
MKFLDLAKVYIRSGAGGNGCVSFRREKFIEYGGPDGGDGGKGGSVWAEAVDGLNTLIDFRYQQHFFAKNGQSGMGRQRSG
KDGDEIVLRVPVGTEILDEDEETVLADLTHVGERVLLAKGGNGGFGNLHFKSSTNQAPRRANSGQEGVERTIWLRLKLIA
DAGLLGLPNAGKSTFLSSTSNARPKIADYPFTTLHPNLGVVGIDNTEFVMADIPGLIEGAHEGRGIGDRFLGHVERCAVL
LHLVDGTSETVAEDYRTIINELEAYGGELASKPRVTALNKIDALDDEERAEARAALEAEVGAPVLMMSSVSREGLDLVLR
AVRAEIDDDRLRIKQAEASEEEDTPWQP

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=329, Percent_Identity=38.9057750759878, Blast_Score=175, Evalue=5e-44,
Organism=Homo sapiens, GI111955139, Length=299, Percent_Identity=37.7926421404682, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI111955063, Length=133, Percent_Identity=45.8646616541353, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI58761500, Length=98, Percent_Identity=34.6938775510204, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4758796, Length=124, Percent_Identity=35.4838709677419, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4557537, Length=118, Percent_Identity=34.7457627118644, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1789574, Length=355, Percent_Identity=49.5774647887324, Blast_Score=294, Evalue=5e-81,
Organism=Escherichia coli, GI1787454, Length=102, Percent_Identity=35.2941176470588, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1790615, Length=201, Percent_Identity=29.8507462686567, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=37.7300613496933, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17552324, Length=346, Percent_Identity=29.1907514450867, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=154, Percent_Identity=33.7662337662338, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17555344, Length=114, Percent_Identity=31.5789473684211, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71981008, Length=115, Percent_Identity=34.7826086956522, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=170, Percent_Identity=39.4117647058824, Blast_Score=119, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=116, Percent_Identity=34.4827586206897, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321649, Length=168, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI20129375, Length=330, Percent_Identity=35.7575757575758, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=36.3013698630137, Blast_Score=141, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24640873, Length=143, Percent_Identity=29.3706293706294, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640877, Length=143, Percent_Identity=29.3706293706294, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24640875, Length=143, Percent_Identity=29.3706293706294, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19921908, Length=160, Percent_Identity=28.125, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17981711, Length=114, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21356473, Length=118, Percent_Identity=33.8983050847458, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_SILST (Q1GHD0)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_613198.1
- ProteinModelPortal:   Q1GHD0
- SMR:   Q1GHD0
- STRING:   Q1GHD0
- GeneID:   4076338
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_1203
- NMPDR:   fig|292414.1.peg.3665
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- PhylomeDB:   Q1GHD0
- ProtClustDB:   PRK12299
- BioCyc:   SSP292414:TM1040_1203-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 37574; Mature: 37574

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLDLAKVYIRSGAGGNGCVSFRREKFIEYGGPDGGDGGKGGSVWAEAVDGLNTLIDFR
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YQQHFFAKNGQSGMGRQRSGKDGDEIVLRVPVGTEILDEDEETVLADLTHVGERVLLAKG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHCCCEEEEEEC
GNGGFGNLHFKSSTNQAPRRANSGQEGVERTIWLRLKLIADAGLLGLPNAGKSTFLSSTS
CCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCCHHEECCCC
NARPKIADYPFTTLHPNLGVVGIDNTEFVMADIPGLIEGAHEGRGIGDRFLGHVERCAVL
CCCCCCCCCCCEEECCCCCEEECCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVDGTSETVAEDYRTIINELEAYGGELASKPRVTALNKIDALDDEERAEARAALEAEV
HHHHCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHC
GAPVLMMSSVSREGLDLVLRAVRAEIDDDRLRIKQAEASEEEDTPWQP
CCCEEEHHHHCHHHHHHHHHHHHHCCCCHHHEEEHHHCCCCCCCCCCC
>Mature Secondary Structure
MKFLDLAKVYIRSGAGGNGCVSFRREKFIEYGGPDGGDGGKGGSVWAEAVDGLNTLIDFR
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
YQQHFFAKNGQSGMGRQRSGKDGDEIVLRVPVGTEILDEDEETVLADLTHVGERVLLAKG
HHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHCCCEEEEEEC
GNGGFGNLHFKSSTNQAPRRANSGQEGVERTIWLRLKLIADAGLLGLPNAGKSTFLSSTS
CCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCCCCHHEECCCC
NARPKIADYPFTTLHPNLGVVGIDNTEFVMADIPGLIEGAHEGRGIGDRFLGHVERCAVL
CCCCCCCCCCCEEECCCCCEEECCCCCEEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHH
LHLVDGTSETVAEDYRTIINELEAYGGELASKPRVTALNKIDALDDEERAEARAALEAEV
HHHHCCCHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHC
GAPVLMMSSVSREGLDLVLRAVRAEIDDDRLRIKQAEASEEEDTPWQP
CCCEEEHHHHCHHHHHHHHHHHHHCCCCHHHEEEHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA