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The map label for this gene is coaX

Identifier: 99080603

GI number: 99080603

Start: 818036

End: 818818

Strand: Direct

Name: coaX

Synonym: TM1040_0762

Alternate gene names: 99080603

Gene position: 818036-818818 (Clockwise)

Preceding gene: 99080602

Following gene: 99080604

Centisome position: 25.56

GC content: 58.88

Gene sequence:

>783_bases
ATGCTTCTCGCGGTTGATTGCGGCAATACTAACACGGTTTTTGCGCTCTGGGATGGCGATCAGATGATCGGCCACTGGCG
CACGTCGACCGAATGGCAGCGCACGGCGGATCAGTATTATGTCTGGCTCTCCACCTTGATGAACCTGCAGGGCATCAAGG
CTCAGATCACGGATATGATTATCTCGTCGACCGTGCCGCGTGTCGTGTTCAACCTGCGCGTTCTGTCGGACCGCTACTTC
AACACCCGCCCGCTGGTGGTGGGTAAACCCGAATGCGCGCTTCCGGTGGATGTGCGCGTCGACGAAGGTACCACCGTCGG
CCCGGACCGGCTGGTCAATACGGTGGCGGGGTATGAAAAATATGGCGGTGATCTGATCGTCGTCGATTTTGGAACCGCAA
CTACATTCGATGTGGTGGCCGCCGACGGCGCCTATGTGGGCGGAGTCATCGCGCCGGGGGTGAACCTCAGCCTGGAGGCG
TTGCACCATGCCGCCGCCGCGCTGCCACACGTCGACATTTCGAAACCACAGAATGTCATCGGCACCAACACGGTGGCCTG
CATGCAGTCTGGCGTCTTCTGGGGCTATGTCGGCCTCGTGCGCGAGATCTGCGATCGCATCAAGGCCGAATCCGGTGTGC
CGATGAAAGTCATATCAACCGGCGGGCTGGCGCCGCTCTTCCAGCAGACAGCAGATCTATTTGACGCATATGAGGATGAC
CTGACCATGCAAGGTCTGAGGCGCATCCACGAGCATAACAAGGATATCGGTAATCACGCATGA

Upstream 100 bases:

>100_bases
TTGAAACCATCGACGACGCGGGCAACCTCGTTCTCAAGACCGCAAAGGGGATCGTCACCATCCCCGCAGCGGACATCTTT
TTCTGACGGAGGCGGGGTAT

Downstream 100 bases:

>100_bases
GCAGTGAAAGACTAATCTATTTGCCCCTCGGCGGGGCAGGCGAAATCGGCATGAACGCCTACGTCTACGGCTATGGTGCG
CCGGGCAAGGAACGGCTGAT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MLLAVDCGNTNTVFALWDGDQMIGHWRTSTEWQRTADQYYVWLSTLMNLQGIKAQITDMIISSTVPRVVFNLRVLSDRYF
NTRPLVVGKPECALPVDVRVDEGTTVGPDRLVNTVAGYEKYGGDLIVVDFGTATTFDVVAADGAYVGGVIAPGVNLSLEA
LHHAAAALPHVDISKPQNVIGTNTVACMQSGVFWGYVGLVREICDRIKAESGVPMKVISTGGLAPLFQQTADLFDAYEDD
LTMQGLRRIHEHNKDIGNHA

Sequences:

>Translated_260_residues
MLLAVDCGNTNTVFALWDGDQMIGHWRTSTEWQRTADQYYVWLSTLMNLQGIKAQITDMIISSTVPRVVFNLRVLSDRYF
NTRPLVVGKPECALPVDVRVDEGTTVGPDRLVNTVAGYEKYGGDLIVVDFGTATTFDVVAADGAYVGGVIAPGVNLSLEA
LHHAAAALPHVDISKPQNVIGTNTVACMQSGVFWGYVGLVREICDRIKAESGVPMKVISTGGLAPLFQQTADLFDAYEDD
LTMQGLRRIHEHNKDIGNHA
>Mature_260_residues
MLLAVDCGNTNTVFALWDGDQMIGHWRTSTEWQRTADQYYVWLSTLMNLQGIKAQITDMIISSTVPRVVFNLRVLSDRYF
NTRPLVVGKPECALPVDVRVDEGTTVGPDRLVNTVAGYEKYGGDLIVVDFGTATTFDVVAADGAYVGGVIAPGVNLSLEA
LHHAAAALPHVDISKPQNVIGTNTVACMQSGVFWGYVGLVREICDRIKAESGVPMKVISTGGLAPLFQQTADLFDAYEDD
LTMQGLRRIHEHNKDIGNHA

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_SILST (Q1GIM1)

Other databases:

- EMBL:   CP000377
- RefSeq:   YP_612757.1
- ProteinModelPortal:   Q1GIM1
- SMR:   Q1GIM1
- STRING:   Q1GIM1
- GeneID:   4076171
- GenomeReviews:   CP000377_GR
- KEGG:   sit:TM1040_0762
- NMPDR:   fig|292414.1.peg.2865
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13318
- BioCyc:   SSP292414:TM1040_0762-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28340; Mature: 28340

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAVDCGNTNTVFALWDGDQMIGHWRTSTEWQRTADQYYVWLSTLMNLQGIKAQITDMI
CEEEEECCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ISSTVPRVVFNLRVLSDRYFNTRPLVVGKPECALPVDVRVDEGTTVGPDRLVNTVAGYEK
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
YGGDLIVVDFGTATTFDVVAADGAYVGGVIAPGVNLSLEALHHAAAALPHVDISKPQNVI
HCCCEEEEECCCCCEEEEEECCCCEECCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GTNTVACMQSGVFWGYVGLVREICDRIKAESGVPMKVISTGGLAPLFQQTADLFDAYEDD
CCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
LTMQGLRRIHEHNKDIGNHA
HHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLLAVDCGNTNTVFALWDGDQMIGHWRTSTEWQRTADQYYVWLSTLMNLQGIKAQITDMI
CEEEEECCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ISSTVPRVVFNLRVLSDRYFNTRPLVVGKPECALPVDVRVDEGTTVGPDRLVNTVAGYEK
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
YGGDLIVVDFGTATTFDVVAADGAYVGGVIAPGVNLSLEALHHAAAALPHVDISKPQNVI
HCCCEEEEECCCCCEEEEEECCCCEECCEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GTNTVACMQSGVFWGYVGLVREICDRIKAESGVPMKVISTGGLAPLFQQTADLFDAYEDD
CCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
LTMQGLRRIHEHNKDIGNHA
HHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA