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The map label for this gene is nuoL [H]

Identifier: 99080599

GI number: 99080599

Start: 812049

End: 814169

Strand: Direct

Name: nuoL [H]

Synonym: TM1040_0758

Alternate gene names: 99080599

Gene position: 812049-814169 (Clockwise)

Preceding gene: 99080598

Following gene: 99080600

Centisome position: 25.37

GC content: 58.46

Gene sequence:

>2121_bases
ATGGAAACCATTCTCCTCTTTGCCCCTCTGGTGGGGGCTGTGATCTGCGGCTTTGGCCATAAGATCATCGGTGAAAAAGC
CGCCATGTGGACTGCCACGGGCCTCTTGTTCCTGACGGCGCTCTTGTCGTGGATCGTCTTCATCAGCTTTGATGGCGAAA
CCCGCATCATCGAGATCTTCCGCTGGATCGAGAGCGGTAGCCTCTCGACCTCTTGGTCGATCCGCCTGGACCGGCTGACC
GCGATCATGCTGATCGTGATCACCACCGTGTCGGCGCTCGTGCATCTCTATTCCTTTGGTTACATGGATCACGACCCGCA
GTGGAAAGAGGGCGAGAGCTACAAGCCACGTTTCTTTGCGTATCTGTCGTTCTTTACCTTCGCCATGCTGATGCTGGTCA
CATCTGACAACCTCGTGCAGATGTTCTTCGGCTGGGAAGGCGTGGGCGTCGCATCTTACCTGCTGATTGGTTTCTACTAC
CGCAAGCCCTCTGCCGGCGCGGCGGCGATGAAAGCATTCATCGTCAACCGTGTGGGCGACTTTGGCTTCTCGCTGGGGAT
CTTTGCGCTGTTCTTCCTCACCGACAGCATCAACCTCGGCACCATCTTTGCGGCAACGCCGGATCTGGCCGAGATGACCG
TGTCCTTCCTCTGGACAGAGTGGAATGCGGCCAATCTGATTGCCTTCCTGCTGTTTGTTGGCGCGATGGGCAAATCGGCG
CAGCTGATCCTGCACACCTGGCTGCCGGACGCGATGGAGGGCCCGACACCGGTTTCGGCACTTATTCACGCGGCAACCAT
GGTGACGGCGGGCGTGTTCCTTGTGTGCCGCATGTCGCCACTGATGGAAGTGGCTCCCGAAGCGACTGCCTTTATCACCG
TGCTCGGTGCGACCACCGCCTTCTTTGCTGCAACCGTGGGTCTGGTTCAGACCGACATCAAGCGCGTGATTGCCTATTCG
ACCTGTTCGCAGCTTGGGTACATGTTTGTCGCCGCAGGTGTGGGCATGTACTCGGCCGCGATGTTCCACCTGTTCACACA
CGCCTTCTTTAAGGCGATGCTGTTCCTTGGCGCGGGTTCCGTGATCCACGCCATGCATCACGAGCAGGACATGATGAACT
ATGGTGGCCTGCGCAAAAAGATCCCCTATACCTTCTGGGCGATGATGATCGGCACGCTCGCCATCACCGGCGTTGGTGTC
CCGGTCTGGATCATGAAGCTGGGCGAAATTCCGATCGGCTTTGCGGGCTTCCATTCCAAGGATGCCATCGTCGAGAGCGC
CTATGCCGCCGGGTCGGCCTATGGGTTCTGGATGCTGGTGATCGCCGCCCTGTTCACAAGCTTCTATAGCTGGCGCCTAA
TGTTCCTGACGTTTTATGGGAAGCCGCGCGGAGACAAGCATACCCACGAGCATGCACACGAGAGCCCGATGGTCATGCTG
ATCCCGCTAGGCGTCTTGGCGCTGGGGGCGATCTTTGCCGGGATGCTGTGGTACAAATCCTTCTTCGGCCACACCGACCA
GGTCGCGAAATTCTACGGCGTGCCTTATGCAGAGGCCTCTGCAGAGGCGCATGGCGATGACCACGCGTCCGACGACCACG
GCGCTGACGCATCCCATGGCGGCGGTGATAAAGAGGCAGAGCATCACTATGTCTTTGCTGGCGAGCCGGGCGAGGGTGCG
CTGTACATGGCGCCCGACAATACGCTTTTGGATGACGCGCATAAGGTTCCGTATTGGGTGAAAACCTCGCCCTTCATGGC
GATGCTTGTCGGGTTCCTCGTGGCCTATTGGTTCTACATCGTGAACCCGGAGCTGCCCAAGCGCCTGTCGCAGCAGCAGC
GCCCGCTCTACCTGTTCCTCAAGAACAAGTGGTATTTTGACGAGCTTTACAACGTGGTCTTTGTCAAACCCGCTCTGGCA
CTTGGCCGCTTCTTCTGGAAGAAGGGCGACGGAAAGACCATTGATGGCTTCCTCAACGGCGTGGCGATGGGGATTGTGCC
CTTCTTCACTCGTCTCGCTGGCCGGGCCCAGTCCGGTTACATCTTCACTTATGCCTTCTGGATGGTGCTCGGGATCGCAG
CCCTTGTCACCTGGATGTCGATCGGCGGAGGATCGCACTGA

Upstream 100 bases:

>100_bases
CTGCTGAGGCCGCGATTGGTCTGGCGATCCTCGTCTGCTTCTTCCGCAACCGCGGCACCATCGCTGTCGAAGACATCAAC
GTGATGAAGGGCTAATCCAG

Downstream 100 bases:

>100_bases
TGGACAATATTCTCTCCATCGTAACCTTCATTCCCGCACTGGCGGCCGCCGTGATGGCGCTGTTGATGCGCGGAGACGAC
GAGGCCGCACAGCGCAACGC

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
METILLFAPLVGAVICGFGHKIIGEKAAMWTATGLLFLTALLSWIVFISFDGETRIIEIFRWIESGSLSTSWSIRLDRLT
AIMLIVITTVSALVHLYSFGYMDHDPQWKEGESYKPRFFAYLSFFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFYY
RKPSAGAAAMKAFIVNRVGDFGFSLGIFALFFLTDSINLGTIFAATPDLAEMTVSFLWTEWNAANLIAFLLFVGAMGKSA
QLILHTWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPLMEVAPEATAFITVLGATTAFFAATVGLVQTDIKRVIAYS
TCSQLGYMFVAAGVGMYSAAMFHLFTHAFFKAMLFLGAGSVIHAMHHEQDMMNYGGLRKKIPYTFWAMMIGTLAITGVGV
PVWIMKLGEIPIGFAGFHSKDAIVESAYAAGSAYGFWMLVIAALFTSFYSWRLMFLTFYGKPRGDKHTHEHAHESPMVML
IPLGVLALGAIFAGMLWYKSFFGHTDQVAKFYGVPYAEASAEAHGDDHASDDHGADASHGGGDKEAEHHYVFAGEPGEGA
LYMAPDNTLLDDAHKVPYWVKTSPFMAMLVGFLVAYWFYIVNPELPKRLSQQQRPLYLFLKNKWYFDELYNVVFVKPALA
LGRFFWKKGDGKTIDGFLNGVAMGIVPFFTRLAGRAQSGYIFTYAFWMVLGIAALVTWMSIGGGSH

Sequences:

>Translated_706_residues
METILLFAPLVGAVICGFGHKIIGEKAAMWTATGLLFLTALLSWIVFISFDGETRIIEIFRWIESGSLSTSWSIRLDRLT
AIMLIVITTVSALVHLYSFGYMDHDPQWKEGESYKPRFFAYLSFFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFYY
RKPSAGAAAMKAFIVNRVGDFGFSLGIFALFFLTDSINLGTIFAATPDLAEMTVSFLWTEWNAANLIAFLLFVGAMGKSA
QLILHTWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPLMEVAPEATAFITVLGATTAFFAATVGLVQTDIKRVIAYS
TCSQLGYMFVAAGVGMYSAAMFHLFTHAFFKAMLFLGAGSVIHAMHHEQDMMNYGGLRKKIPYTFWAMMIGTLAITGVGV
PVWIMKLGEIPIGFAGFHSKDAIVESAYAAGSAYGFWMLVIAALFTSFYSWRLMFLTFYGKPRGDKHTHEHAHESPMVML
IPLGVLALGAIFAGMLWYKSFFGHTDQVAKFYGVPYAEASAEAHGDDHASDDHGADASHGGGDKEAEHHYVFAGEPGEGA
LYMAPDNTLLDDAHKVPYWVKTSPFMAMLVGFLVAYWFYIVNPELPKRLSQQQRPLYLFLKNKWYFDELYNVVFVKPALA
LGRFFWKKGDGKTIDGFLNGVAMGIVPFFTRLAGRAQSGYIFTYAFWMVLGIAALVTWMSIGGGSH
>Mature_706_residues
METILLFAPLVGAVICGFGHKIIGEKAAMWTATGLLFLTALLSWIVFISFDGETRIIEIFRWIESGSLSTSWSIRLDRLT
AIMLIVITTVSALVHLYSFGYMDHDPQWKEGESYKPRFFAYLSFFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFYY
RKPSAGAAAMKAFIVNRVGDFGFSLGIFALFFLTDSINLGTIFAATPDLAEMTVSFLWTEWNAANLIAFLLFVGAMGKSA
QLILHTWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPLMEVAPEATAFITVLGATTAFFAATVGLVQTDIKRVIAYS
TCSQLGYMFVAAGVGMYSAAMFHLFTHAFFKAMLFLGAGSVIHAMHHEQDMMNYGGLRKKIPYTFWAMMIGTLAITGVGV
PVWIMKLGEIPIGFAGFHSKDAIVESAYAAGSAYGFWMLVIAALFTSFYSWRLMFLTFYGKPRGDKHTHEHAHESPMVML
IPLGVLALGAIFAGMLWYKSFFGHTDQVAKFYGVPYAEASAEAHGDDHASDDHGADASHGGGDKEAEHHYVFAGEPGEGA
LYMAPDNTLLDDAHKVPYWVKTSPFMAMLVGFLVAYWFYIVNPELPKRLSQQQRPLYLFLKNKWYFDELYNVVFVKPALA
LGRFFWKKGDGKTIDGFLNGVAMGIVPFFTRLAGRAQSGYIFTYAFWMVLGIAALVTWMSIGGGSH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=463, Percent_Identity=38.6609071274298, Blast_Score=294, Evalue=2e-79,
Organism=Escherichia coli, GI1788614, Length=492, Percent_Identity=41.869918699187, Blast_Score=341, Evalue=1e-94,
Organism=Escherichia coli, GI1788829, Length=491, Percent_Identity=27.4949083503055, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1788831, Length=368, Percent_Identity=28.5326086956522, Blast_Score=112, Evalue=1e-25,
Organism=Escherichia coli, GI1788827, Length=452, Percent_Identity=27.6548672566372, Blast_Score=109, Evalue=5e-25,
Organism=Escherichia coli, GI1788613, Length=487, Percent_Identity=25.6673511293634, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI2367154, Length=229, Percent_Identity=27.9475982532751, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 77996; Mature: 77996

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METILLFAPLVGAVICGFGHKIIGEKAAMWTATGLLFLTALLSWIVFISFDGETRIIEIF
CCEEEHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
RWIESGSLSTSWSIRLDRLTAIMLIVITTVSALVHLYSFGYMDHDPQWKEGESYKPRFFA
HHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
YLSFFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFYYRKPSAGAAAMKAFIVNRVGD
HHHHHHHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FGFSLGIFALFFLTDSINLGTIFAATPDLAEMTVSFLWTEWNAANLIAFLLFVGAMGKSA
HHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
QLILHTWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPLMEVAPEATAFITVLGATTA
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHH
FFAATVGLVQTDIKRVIAYSTCSQLGYMFVAAGVGMYSAAMFHLFTHAFFKAMLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIHAMHHEQDMMNYGGLRKKIPYTFWAMMIGTLAITGVGVPVWIMKLGEIPIGFAGFHSK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCCC
DAIVESAYAAGSAYGFWMLVIAALFTSFYSWRLMFLTFYGKPRGDKHTHEHAHESPMVML
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHCCCCEEEE
IPLGVLALGAIFAGMLWYKSFFGHTDQVAKFYGVPYAEASAEAHGDDHASDDHGADASHG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCC
GGDKEAEHHYVFAGEPGEGALYMAPDNTLLDDAHKVPYWVKTSPFMAMLVGFLVAYWFYI
CCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
VNPELPKRLSQQQRPLYLFLKNKWYFDELYNVVFVKPALALGRFFWKKGDGKTIDGFLNG
CCCHHHHHHHHCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAMGIVPFFTRLAGRAQSGYIFTYAFWMVLGIAALVTWMSIGGGSH
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
METILLFAPLVGAVICGFGHKIIGEKAAMWTATGLLFLTALLSWIVFISFDGETRIIEIF
CCEEEHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHH
RWIESGSLSTSWSIRLDRLTAIMLIVITTVSALVHLYSFGYMDHDPQWKEGESYKPRFFA
HHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHH
YLSFFTFAMLMLVTSDNLVQMFFGWEGVGVASYLLIGFYYRKPSAGAAAMKAFIVNRVGD
HHHHHHHHHHHHHHCCCCEEHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
FGFSLGIFALFFLTDSINLGTIFAATPDLAEMTVSFLWTEWNAANLIAFLLFVGAMGKSA
HHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCC
QLILHTWLPDAMEGPTPVSALIHAATMVTAGVFLVCRMSPLMEVAPEATAFITVLGATTA
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHHH
FFAATVGLVQTDIKRVIAYSTCSQLGYMFVAAGVGMYSAAMFHLFTHAFFKAMLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIHAMHHEQDMMNYGGLRKKIPYTFWAMMIGTLAITGVGVPVWIMKLGEIPIGFAGFHSK
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEECCCCCC
DAIVESAYAAGSAYGFWMLVIAALFTSFYSWRLMFLTFYGKPRGDKHTHEHAHESPMVML
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHCCCCEEEE
IPLGVLALGAIFAGMLWYKSFFGHTDQVAKFYGVPYAEASAEAHGDDHASDDHGADASHG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHCCCCCCCCCCCCCCCCCCCCCC
GGDKEAEHHYVFAGEPGEGALYMAPDNTLLDDAHKVPYWVKTSPFMAMLVGFLVAYWFYI
CCCCCCCCEEEEECCCCCCEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHH
VNPELPKRLSQQQRPLYLFLKNKWYFDELYNVVFVKPALALGRFFWKKGDGKTIDGFLNG
CCCHHHHHHHHCCCCEEEEEECCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
VAMGIVPFFTRLAGRAQSGYIFTYAFWMVLGIAALVTWMSIGGGSH
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]