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The map label for this gene is 99080596

Identifier: 99080596

GI number: 99080596

Start: 810750

End: 811124

Strand: Direct

Name: 99080596

Synonym: TM1040_0755

Alternate gene names: NA

Gene position: 810750-811124 (Clockwise)

Preceding gene: 99080595

Following gene: 99080597

Centisome position: 25.33

GC content: 60.27

Gene sequence:

>375_bases
ATGGCCCAGGCGCAGGAGATGGCGAAGGCCCTCAATCCTGCGCTAGAGAGTTTCTCTCCCAAGGGGTTTGAGGCGCTCTG
GCCCACCATGCCCAAAGAGGTCATGGAGATGATGTTCGGCAACACCGTCAACAAAGACGGGCTTGATGCCAAAACCCGCC
TGCTGCTGACGCTGGCGGGATTGACCATGCAGGGCGCGCAGGCCGATACGGCCGTGCGTCAGACCGTGCGCCACGCTCTT
GCGGCGGGCGCAAAGAAACAAGAGATCGTTGAAACGATCGGACAGATGTCGGTCTTTGCCGGCATTCCGGCCATGACCCG
CGCAATGGATTTGGCGCAGGAGGTCATGGACGACAAAGGGGACGATGAGACATGA

Upstream 100 bases:

>100_bases
TGGCGAATGGCGAGCGCTGGGAAGCCGAGATTGCCCGCAATCTTGAGCTGGACGCGCCCTACAGATGAGCGAGACGCCGA
AAAACCCTTTCGAGGCCATG

Downstream 100 bases:

>100_bases
GCGTTTTTGCCTTTTACCTCTTCGCCATCAGCGCCATCACCGGCGGGCTGTTCACAGTGATCAGCCGCCAGCCGGTGCAC
TCGGTGCTGTGGCTCATTTT

Product: carboxymuconolactone decarboxylase

Products: 4,5-dihydro-5-oxofuran-2-acetate; CO2

Alternate protein names: URF6 [H]

Number of amino acids: Translated: 124; Mature: 123

Protein sequence:

>124_residues
MAQAQEMAKALNPALESFSPKGFEALWPTMPKEVMEMMFGNTVNKDGLDAKTRLLLTLAGLTMQGAQADTAVRQTVRHAL
AAGAKKQEIVETIGQMSVFAGIPAMTRAMDLAQEVMDDKGDDET

Sequences:

>Translated_124_residues
MAQAQEMAKALNPALESFSPKGFEALWPTMPKEVMEMMFGNTVNKDGLDAKTRLLLTLAGLTMQGAQADTAVRQTVRHAL
AAGAKKQEIVETIGQMSVFAGIPAMTRAMDLAQEVMDDKGDDET
>Mature_123_residues
AQAQEMAKALNPALESFSPKGFEALWPTMPKEVMEMMFGNTVNKDGLDAKTRLLLTLAGLTMQGAQADTAVRQTVRHALA
AGAKKQEIVETIGQMSVFAGIPAMTRAMDLAQEVMDDKGDDET

Specific function: May have a role in the regulation of NDH-1 biosynthesis [H]

COG id: COG0599

COG function: function code S; Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003779 [H]

Pfam domain/function: PF02627 CMD [H]

EC number: 4.1.1.44

Molecular weight: Translated: 13374; Mature: 13242

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
8.9 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.1 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAQEMAKALNPALESFSPKGFEALWPTMPKEVMEMMFGNTVNKDGLDAKTRLLLTLAG
CCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LTMQGAQADTAVRQTVRHALAAGAKKQEIVETIGQMSVFAGIPAMTRAMDLAQEVMDDKG
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DDET
CCCC
>Mature Secondary Structure 
AQAQEMAKALNPALESFSPKGFEALWPTMPKEVMEMMFGNTVNKDGLDAKTRLLLTLAG
CHHHHHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
LTMQGAQADTAVRQTVRHALAAGAKKQEIVETIGQMSVFAGIPAMTRAMDLAQEVMDDKG
HHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DDET
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate

Specific reaction: 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 4,5-dihydro-5-oxofuran-2-acetate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]