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The map label for this gene is appB [H]

Identifier: 99080555

GI number: 99080555

Start: 768727

End: 769734

Strand: Reverse

Name: appB [H]

Synonym: TM1040_0714

Alternate gene names: 99080555

Gene position: 769734-768727 (Counterclockwise)

Preceding gene: 99080556

Following gene: 99080554

Centisome position: 24.05

GC content: 58.73

Gene sequence:

>1008_bases
ATGCTGACTTTTACCATCCGACGGCTGATCATAGCAGTGCCGACACTGCTGTTCATCAGTCTCGTGATCTTCCTGCTGCT
GGAACTCGCCCCCGGCGATCCCATGGCACAGGTTCCCCTGACCGTCCCCCCCGAAGTGAAAGAGAAGATGCGCCTGGCCC
TCGGCCTTGGCGAGCCCGTCCATATCCGGTTCTGGAAATGGCTGGTGCAGTTCTTCTGGATCGAACCTCAGGTTCTGATC
GACCATATCTTTGGCACATCCTTTTCCGCAGGCGATCTGCGTGTCATCTCCTGGCAGACCCGGTCTCCGGTGATGGACAT
CGTGGTGCAGCGCTTGCCGCAGACCCTCTGGGTTGTGGGCACCGCCTATATCGTGGCCATCCTGATCGCCCTGCCCATCG
GCATCTACTCTGCCTACCGCCAGTACAGCTGGTTCGACCAGATGGGGACATTCGTCTCCATGGTGGGCTTCTCGGTGCCG
CCGTTCTTCTCTGGTGTTCTGGTCATCGTGATCTTCTCGGTTCAGCTTGGCTGGTTCCCGTCGATCTATGACACCACGCT
CGAGGTCAACAGCTGGGAAACCTTCGTGAAGCAGCTCCAGCAGATGGTGATGCCGGTGATGGTACTGGCACTTCAGATCA
CCGCACAGCTCAGCCGGTTCATGCGCGCCTCCATGCTCGACAACCTTAACCAGGACTACGTGCGCACCGCGCGCGCCAAG
GGCCTGGGCGAGTATACGGTTGTCATGGTGCATGTGCTGCGCAATTCCATGATCCCGGTTGTCACCGTGATCGCCCTGGG
CATTCCGTCGATCTTTGGCGGCGCCATCATCACCGAACAGGTGTTCAAGGTGAACGGGATTGGCCAGTTGCTGATCGGCG
CCATCCAGGCCAACGACCTGCCTATGGTGCAGACGCTTACCTTCATCTTTGCCGTGCTCATCGTGCTGTTCAACCTGATC
GCCGATGTGCTCTACGGCATTCTCGACCCGAGGATCCGCTATGACTGA

Upstream 100 bases:

>100_bases
TGGACTTGGCTTAAGAGACCCGCCATCACGCGACACCCGCCCGACAAGGGCAAGGCAAACGCGGACCTGTCGACAACCCA
TTTGCAAAGGCGCCCGGCTG

Downstream 100 bases:

>100_bases
CGCTGCAAAAGAAAAGACCCTGCAGCACTCCAGCGTGCAGGACGAACTCGCCACACCCGCCCGCAGCCAGTGGCGCGAGA
TCTGGGTTCAGTTCAAATCG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MLTFTIRRLIIAVPTLLFISLVIFLLLELAPGDPMAQVPLTVPPEVKEKMRLALGLGEPVHIRFWKWLVQFFWIEPQVLI
DHIFGTSFSAGDLRVISWQTRSPVMDIVVQRLPQTLWVVGTAYIVAILIALPIGIYSAYRQYSWFDQMGTFVSMVGFSVP
PFFSGVLVIVIFSVQLGWFPSIYDTTLEVNSWETFVKQLQQMVMPVMVLALQITAQLSRFMRASMLDNLNQDYVRTARAK
GLGEYTVVMVHVLRNSMIPVVTVIALGIPSIFGGAIITEQVFKVNGIGQLLIGAIQANDLPMVQTLTFIFAVLIVLFNLI
ADVLYGILDPRIRYD

Sequences:

>Translated_335_residues
MLTFTIRRLIIAVPTLLFISLVIFLLLELAPGDPMAQVPLTVPPEVKEKMRLALGLGEPVHIRFWKWLVQFFWIEPQVLI
DHIFGTSFSAGDLRVISWQTRSPVMDIVVQRLPQTLWVVGTAYIVAILIALPIGIYSAYRQYSWFDQMGTFVSMVGFSVP
PFFSGVLVIVIFSVQLGWFPSIYDTTLEVNSWETFVKQLQQMVMPVMVLALQITAQLSRFMRASMLDNLNQDYVRTARAK
GLGEYTVVMVHVLRNSMIPVVTVIALGIPSIFGGAIITEQVFKVNGIGQLLIGAIQANDLPMVQTLTFIFAVLIVLFNLI
ADVLYGILDPRIRYD
>Mature_335_residues
MLTFTIRRLIIAVPTLLFISLVIFLLLELAPGDPMAQVPLTVPPEVKEKMRLALGLGEPVHIRFWKWLVQFFWIEPQVLI
DHIFGTSFSAGDLRVISWQTRSPVMDIVVQRLPQTLWVVGTAYIVAILIALPIGIYSAYRQYSWFDQMGTFVSMVGFSVP
PFFSGVLVIVIFSVQLGWFPSIYDTTLEVNSWETFVKQLQQMVMPVMVLALQITAQLSRFMRASMLDNLNQDYVRTARAK
GLGEYTVVMVHVLRNSMIPVVTVIALGIPSIFGGAIITEQVFKVNGIGQLLIGAIQANDLPMVQTLTFIFAVLIVLFNLI
ADVLYGILDPRIRYD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=339, Percent_Identity=35.693215339233, Blast_Score=210, Evalue=1e-55,
Organism=Escherichia coli, GI1789965, Length=356, Percent_Identity=33.9887640449438, Blast_Score=191, Evalue=5e-50,
Organism=Escherichia coli, GI1789888, Length=339, Percent_Identity=31.858407079646, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1787497, Length=334, Percent_Identity=29.940119760479, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1787761, Length=333, Percent_Identity=31.2312312312312, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787550, Length=283, Percent_Identity=26.1484098939929, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788504, Length=380, Percent_Identity=25.7894736842105, Blast_Score=121, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37712; Mature: 37712

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFTIRRLIIAVPTLLFISLVIFLLLELAPGDPMAQVPLTVPPEVKEKMRLALGLGEPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCH
HIRFWKWLVQFFWIEPQVLIDHIFGTSFSAGDLRVISWQTRSPVMDIVVQRLPQTLWVVG
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
TAYIVAILIALPIGIYSAYRQYSWFDQMGTFVSMVGFSVPPFFSGVLVIVIFSVQLGWFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
SIYDTTLEVNSWETFVKQLQQMVMPVMVLALQITAQLSRFMRASMLDNLNQDYVRTARAK
CHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GLGEYTVVMVHVLRNSMIPVVTVIALGIPSIFGGAIITEQVFKVNGIGQLLIGAIQANDL
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
PMVQTLTFIFAVLIVLFNLIADVLYGILDPRIRYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLTFTIRRLIIAVPTLLFISLVIFLLLELAPGDPMAQVPLTVPPEVKEKMRLALGLGEPV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCH
HIRFWKWLVQFFWIEPQVLIDHIFGTSFSAGDLRVISWQTRSPVMDIVVQRLPQTLWVVG
HHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
TAYIVAILIALPIGIYSAYRQYSWFDQMGTFVSMVGFSVPPFFSGVLVIVIFSVQLGWFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCC
SIYDTTLEVNSWETFVKQLQQMVMPVMVLALQITAQLSRFMRASMLDNLNQDYVRTARAK
CHHHCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
GLGEYTVVMVHVLRNSMIPVVTVIALGIPSIFGGAIITEQVFKVNGIGQLLIGAIQANDL
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
PMVQTLTFIFAVLIVLFNLIADVLYGILDPRIRYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]