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The map label for this gene is pepT [H]

Identifier: 99080489

GI number: 99080489

Start: 691865

End: 693112

Strand: Reverse

Name: pepT [H]

Synonym: TM1040_0648

Alternate gene names: 99080489

Gene position: 693112-691865 (Counterclockwise)

Preceding gene: 99080490

Following gene: 99080488

Centisome position: 21.65

GC content: 60.34

Gene sequence:

>1248_bases
ATGACCGACAGCTTTGACAACACCCTTCAATCCCGTCTCGTGCGCTATGCTGCCATCGACAGCCAGAGCGATGAGAATTC
CCCCACGGCACCCAGCACCAAGATCCAGTTTGATATGTTGCACTTGGTGCGCGACGAGTTGACCGAGATCGGAGCGCAAG
ACGTGCAGCTGACCGATTACGGCGTTGTTCTGGCGACTATCCCCGGCAGGTCGGAGGCCCCCACAGTGGGCTTCCTCGCC
CATGTCGACACTGCCCCGCAGTTCAATGCCACCGGTGTGAAACCTCGTGTGATCAAAGGGTACAATGGCGGCGAGATCAG
CTTTCCCGATGATCCGGAGCTGGTGCTCTCTCCCGAGGCGCACCCCTATCTGGCCGAGAAAATCGGCCATGATCTGATCA
CTGCGTCTGGCACCACATTGCTTGGGGCGGACGACAAGGCGGGGGTTGCGATCATAATGACGATGGCAGAGCACCTGCTG
CAAAACCCGGATGCCGCCCGTCCAACAATCCGGATTGCCTTCACTCCGGACGAAGAGATCGGTCGCGGCGTGCAACCCCA
GCTGGAGCGCGACCTCGGGGCGGATTTTGCCTATACGCTCGATGGCGGGGAACTCGGCGAAGTGGAGTACGAGAGCTTTT
CGGCCGACCGCGCAGTTGTCAAAATCACCGGCGTTTCCATTCACCCGGGCCTCGCCAAGGAAAAGATGGTCAATGCCATC
CATCTTGCCTCCAAGATCATCCAGACGCTGCCTCAGGCCACGATGACGCCCGAGACAACAGCGGACCGCGAGGGGTTCAT
CCATGCCACCGACATGTTCGGGGGGTCTTCCGAGATGGAGATCCGCTTCATCCTGCGCGATTTTGAAATGGCCGATCTTG
AGGCCAAGGGCGCCCTTCTACGCAGCGTCTGCGAGGCGGTTGCGGCAACCGAACCGCGCGCGGAGATCACCTGCGAGATT
ACCCCGCAATATCGCAACATGCGGTATTGGCTTGAAAAGGACATGACCCCTGTCGATCTCGCCCATGCCGCCTGCCGCGA
TGTGGGACTGGAGCCGGTATCGGTTCCGATCCGCGGGGGCACCGATGGGTCTCGCCTGACCGAATTCGGCACGCCGACGC
CCAATATCTTTACGGGGATGCAATGCATTCATGGCCCCTTGGAGTGGATCTCGGTTCAGGATATGTCGCTGGCAACGCAG
ATGTGTCTGAGCCTCGCGGCGCGCGCCGCAACGCTCGACAAGACCTAA

Upstream 100 bases:

>100_bases
ACACCCAATCCGGCCACATTCAGGACGGAGCAGGTTTGAGAGTTCACCTTGACCTGCTCCTCTCCGCCCTCAATCTTGCA
GTCGACAGCAGGAGTTTTTG

Downstream 100 bases:

>100_bases
AACTAACCATGGCGCGCCTTTCGCTCTGCCCCGCAGAGCTGCTAGGCTCCTGCCCTGGGCCGCACAGGAACAAGTGATGC
AACACTACGAGTACAAGGTC

Product: peptidase T

Products: NA

Alternate protein names: Aminotripeptidase; Tripeptidase; Tripeptide aminopeptidase [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTDSFDNTLQSRLVRYAAIDSQSDENSPTAPSTKIQFDMLHLVRDELTEIGAQDVQLTDYGVVLATIPGRSEAPTVGFLA
HVDTAPQFNATGVKPRVIKGYNGGEISFPDDPELVLSPEAHPYLAEKIGHDLITASGTTLLGADDKAGVAIIMTMAEHLL
QNPDAARPTIRIAFTPDEEIGRGVQPQLERDLGADFAYTLDGGELGEVEYESFSADRAVVKITGVSIHPGLAKEKMVNAI
HLASKIIQTLPQATMTPETTADREGFIHATDMFGGSSEMEIRFILRDFEMADLEAKGALLRSVCEAVAATEPRAEITCEI
TPQYRNMRYWLEKDMTPVDLAHAACRDVGLEPVSVPIRGGTDGSRLTEFGTPTPNIFTGMQCIHGPLEWISVQDMSLATQ
MCLSLAARAATLDKT

Sequences:

>Translated_415_residues
MTDSFDNTLQSRLVRYAAIDSQSDENSPTAPSTKIQFDMLHLVRDELTEIGAQDVQLTDYGVVLATIPGRSEAPTVGFLA
HVDTAPQFNATGVKPRVIKGYNGGEISFPDDPELVLSPEAHPYLAEKIGHDLITASGTTLLGADDKAGVAIIMTMAEHLL
QNPDAARPTIRIAFTPDEEIGRGVQPQLERDLGADFAYTLDGGELGEVEYESFSADRAVVKITGVSIHPGLAKEKMVNAI
HLASKIIQTLPQATMTPETTADREGFIHATDMFGGSSEMEIRFILRDFEMADLEAKGALLRSVCEAVAATEPRAEITCEI
TPQYRNMRYWLEKDMTPVDLAHAACRDVGLEPVSVPIRGGTDGSRLTEFGTPTPNIFTGMQCIHGPLEWISVQDMSLATQ
MCLSLAARAATLDKT
>Mature_414_residues
TDSFDNTLQSRLVRYAAIDSQSDENSPTAPSTKIQFDMLHLVRDELTEIGAQDVQLTDYGVVLATIPGRSEAPTVGFLAH
VDTAPQFNATGVKPRVIKGYNGGEISFPDDPELVLSPEAHPYLAEKIGHDLITASGTTLLGADDKAGVAIIMTMAEHLLQ
NPDAARPTIRIAFTPDEEIGRGVQPQLERDLGADFAYTLDGGELGEVEYESFSADRAVVKITGVSIHPGLAKEKMVNAIH
LASKIIQTLPQATMTPETTADREGFIHATDMFGGSSEMEIRFILRDFEMADLEAKGALLRSVCEAVAATEPRAEITCEIT
PQYRNMRYWLEKDMTPVDLAHAACRDVGLEPVSVPIRGGTDGSRLTEFGTPTPNIFTGMQCIHGPLEWISVQDMSLATQM
CLSLAARAATLDKT

Specific function: Cleaves the N-terminal amino acid of tripeptides [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20B family [H]

Homologues:

Organism=Escherichia coli, GI1787372, Length=407, Percent_Identity=39.3120393120393, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR010161 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.11.4 [H]

Molecular weight: Translated: 44976; Mature: 44845

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSFDNTLQSRLVRYAAIDSQSDENSPTAPSTKIQFDMLHLVRDELTEIGAQDVQLTDY
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEECC
GVVLATIPGRSEAPTVGFLAHVDTAPQFNATGVKPRVIKGYNGGEISFPDDPELVLSPEA
CEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCC
HPYLAEKIGHDLITASGTTLLGADDKAGVAIIMTMAEHLLQNPDAARPTIRIAFTPDEEI
CHHHHHHCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHH
GRGVQPQLERDLGADFAYTLDGGELGEVEYESFSADRAVVKITGVSIHPGLAKEKMVNAI
CCCCCCHHHHHCCCCEEEEECCCCCCCEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHH
HLASKIIQTLPQATMTPETTADREGFIHATDMFGGSSEMEIRFILRDFEMADLEAKGALL
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCHHCHHHHHHHH
RSVCEAVAATEPRAEITCEITPQYRNMRYWLEKDMTPVDLAHAACRDVGLEPVSVPIRGG
HHHHHHHHCCCCCCEEEEEECCCHHCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECC
TDGSRLTEFGTPTPNIFTGMQCIHGPLEWISVQDMSLATQMCLSLAARAATLDKT
CCCCHHHHCCCCCCHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDSFDNTLQSRLVRYAAIDSQSDENSPTAPSTKIQFDMLHLVRDELTEIGAQDVQLTDY
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCCEEEECC
GVVLATIPGRSEAPTVGFLAHVDTAPQFNATGVKPRVIKGYNGGEISFPDDPELVLSPEA
CEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEECCCC
HPYLAEKIGHDLITASGTTLLGADDKAGVAIIMTMAEHLLQNPDAARPTIRIAFTPDEEI
CHHHHHHCCCCEEECCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHH
GRGVQPQLERDLGADFAYTLDGGELGEVEYESFSADRAVVKITGVSIHPGLAKEKMVNAI
CCCCCCHHHHHCCCCEEEEECCCCCCCEECCCCCCCCEEEEEEEEEECCCCHHHHHHHHH
HLASKIIQTLPQATMTPETTADREGFIHATDMFGGSSEMEIRFILRDFEMADLEAKGALL
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCHHCHHHHHHHH
RSVCEAVAATEPRAEITCEITPQYRNMRYWLEKDMTPVDLAHAACRDVGLEPVSVPIRGG
HHHHHHHHCCCCCCEEEEEECCCHHCHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECC
TDGSRLTEFGTPTPNIFTGMQCIHGPLEWISVQDMSLATQMCLSLAARAATLDKT
CCCCHHHHCCCCCCHHHHHHHHHCCCHHHEEECHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA