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The map label for this gene is pabB [H]

Identifier: 99080474

GI number: 99080474

Start: 675784

End: 676980

Strand: Direct

Name: pabB [H]

Synonym: TM1040_0633

Alternate gene names: 99080474

Gene position: 675784-676980 (Clockwise)

Preceding gene: 99080472

Following gene: 99080475

Centisome position: 21.11

GC content: 63.49

Gene sequence:

>1197_bases
GTGGCGTCGAAACCGCTATATGCGGGGCAAGGGAGACACTCACTGCTCACGGAGACCCTGCCGGTGGAAATCCGCTTTGA
CAATGGCCCATCGAAGGGCGCGGCGCTGTTTGAAGACCCAGTTGACCTGATCCGCGCGCAAGACCCGGATGAGGTGCAGG
GGGCGCTTGCGGCCTTGGACCGCGCCCGCGCCGAGGGGCATTGGGTTGCAGGCTATGCGTCTTATGAGTTGGGCTATGCG
CTTGAGCCACGTTTGGCGCATCTTCTGAATGGGCGCGGGCACCGGCGTCTTCCGTTGCTGCAGTTCGGTGTGTTCCGCGC
GCCGGTGGCGGCGGATGTTCCGCTTTGGGCTGGGGATGCAGGTGTGGGAGAGACGACCGCGCGCTGGGACGCTGCCCGCT
ACACCGAGGCCTTTGATCGCGTTAAATCCTACATTGGCGCCGGCGACATATATCAGGCCAATCTGACTTTCCCCATCGAC
GCACAGGTCTGGGGCGGGGCGGAGGCGCTTTATGCGGCCCTTGCCGCGCGTCAGCCTGTGGGCCACGGGGCGCTTGTGCG
TCAGGACGGGCTGCCAACGATCCTGTCGCGCAGCCCGGAGCTCTTCTTTCGCACATCCTCGGATGGGGTGATCGAGACGC
GTCCCATGAAGGGCACGCAACCGCGCAGCCTTGACCCGCGAGAGGATTCGCGACGACGGGATTTCCTGCGCTCTGACGAA
AAGAACCGCGCTGAAAACCTGATGATTGTCGACCTTCTGCGCAATGACATCAGCCGCGTGTCCGAGACCGGCTCGGTCCA
TGTGCCAGAGCTGTTTGCCGTGGAAAGCTATGCGACGGTGCACCAGATGGTGTCATTGGTGCGGGCACGCCTCAAGGCCG
GCTGCGGTCTGGCGGACATCTTTGCGGCACTTTATCCCTGCGGGTCGATCACCGGCGCGCCCAAAATCCGTGCCATGGAG
ATCCTTGCGGAACTCGAGCCCGGGGCGCGCGACATTTATTGCGGCACCATTGGCTGGGCGGCCCCCGACGGGCGGTCGGA
ATTCAATGTCTCCATACGTACGATGATGCTGGAGGGCGATGCGGCCACGTTCAACGTCGGCGGTGGGCTGGTCTGGGACA
GCACCTCCGCCTCCGAGTATGAGGAAGCGCTGTGGAAAGCCCGTTTTGCACAAGTGACGACCCCGATTTCCGCTTGA

Upstream 100 bases:

>100_bases
CACGGGCTGCGCCCAAATTGTCCTGCGTTATAGGCAGCGAGACAAAAGGTGCAAGGGGGATCGGCCCTGCAATGCAAATT
GCCGTTTTCGACCCTTTCGT

Downstream 100 bases:

>100_bases
TCGAGACCTTCGGCTTTGCGCCGGGGCAGGGTGTTGCGCGGCTTGATCTGCACTTGGCGCGTCTGACGCGCTCTGCCGAG
GCCTTTGGTATTCCGTTCCG

Product: aminodeoxychorismate synthase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MASKPLYAGQGRHSLLTETLPVEIRFDNGPSKGAALFEDPVDLIRAQDPDEVQGALAALDRARAEGHWVAGYASYELGYA
LEPRLAHLLNGRGHRRLPLLQFGVFRAPVAADVPLWAGDAGVGETTARWDAARYTEAFDRVKSYIGAGDIYQANLTFPID
AQVWGGAEALYAALAARQPVGHGALVRQDGLPTILSRSPELFFRTSSDGVIETRPMKGTQPRSLDPREDSRRRDFLRSDE
KNRAENLMIVDLLRNDISRVSETGSVHVPELFAVESYATVHQMVSLVRARLKAGCGLADIFAALYPCGSITGAPKIRAME
ILAELEPGARDIYCGTIGWAAPDGRSEFNVSIRTMMLEGDAATFNVGGGLVWDSTSASEYEEALWKARFAQVTTPISA

Sequences:

>Translated_398_residues
MASKPLYAGQGRHSLLTETLPVEIRFDNGPSKGAALFEDPVDLIRAQDPDEVQGALAALDRARAEGHWVAGYASYELGYA
LEPRLAHLLNGRGHRRLPLLQFGVFRAPVAADVPLWAGDAGVGETTARWDAARYTEAFDRVKSYIGAGDIYQANLTFPID
AQVWGGAEALYAALAARQPVGHGALVRQDGLPTILSRSPELFFRTSSDGVIETRPMKGTQPRSLDPREDSRRRDFLRSDE
KNRAENLMIVDLLRNDISRVSETGSVHVPELFAVESYATVHQMVSLVRARLKAGCGLADIFAALYPCGSITGAPKIRAME
ILAELEPGARDIYCGTIGWAAPDGRSEFNVSIRTMMLEGDAATFNVGGGLVWDSTSASEYEEALWKARFAQVTTPISA
>Mature_397_residues
ASKPLYAGQGRHSLLTETLPVEIRFDNGPSKGAALFEDPVDLIRAQDPDEVQGALAALDRARAEGHWVAGYASYELGYAL
EPRLAHLLNGRGHRRLPLLQFGVFRAPVAADVPLWAGDAGVGETTARWDAARYTEAFDRVKSYIGAGDIYQANLTFPIDA
QVWGGAEALYAALAARQPVGHGALVRQDGLPTILSRSPELFFRTSSDGVIETRPMKGTQPRSLDPREDSRRRDFLRSDEK
NRAENLMIVDLLRNDISRVSETGSVHVPELFAVESYATVHQMVSLVRARLKAGCGLADIFAALYPCGSITGAPKIRAMEI
LAELEPGARDIYCGTIGWAAPDGRSEFNVSIRTMMLEGDAATFNVGGGLVWDSTSASEYEEALWKARFAQVTTPISA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=255, Percent_Identity=43.1372549019608, Blast_Score=195, Evalue=4e-51,
Organism=Escherichia coli, GI1787518, Length=259, Percent_Identity=33.2046332046332, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1786809, Length=213, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082077, Length=197, Percent_Identity=25.8883248730964, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=194, Percent_Identity=37.6288659793814, Blast_Score=138, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324361, Length=267, Percent_Identity=29.5880149812734, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 43275; Mature: 43144

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKPLYAGQGRHSLLTETLPVEIRFDNGPSKGAALFEDPVDLIRAQDPDEVQGALAALD
CCCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHH
RARAEGHWVAGYASYELGYALEPRLAHLLNGRGHRRLPLLQFGVFRAPVAADVPLWAGDA
HHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCEECCCC
GVGETTARWDAARYTEAFDRVKSYIGAGDIYQANLTFPIDAQVWGGAEALYAALAARQPV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHCCCHHHHHHHHHHCCCC
GHGALVRQDGLPTILSRSPELFFRTSSDGVIETRPMKGTQPRSLDPREDSRRRDFLRSDE
CCCCEEECCCCCHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
KNRAENLMIVDLLRNDISRVSETGSVHVPELFAVESYATVHQMVSLVRARLKAGCGLADI
CHHHCCEEHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FAALYPCGSITGAPKIRAMEILAELEPGARDIYCGTIGWAAPDGRSEFNVSIRTMMLEGD
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEECC
AATFNVGGGLVWDSTSASEYEEALWKARFAQVTTPISA
CEEEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ASKPLYAGQGRHSLLTETLPVEIRFDNGPSKGAALFEDPVDLIRAQDPDEVQGALAALD
CCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCHHHCCHHHHCCCCHHHHHHHHHHHH
RARAEGHWVAGYASYELGYALEPRLAHLLNGRGHRRLPLLQFGVFRAPVAADVPLWAGDA
HHHCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCEECCCC
GVGETTARWDAARYTEAFDRVKSYIGAGDIYQANLTFPIDAQVWGGAEALYAALAARQPV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCHHCCCHHHHHHHHHHCCCC
GHGALVRQDGLPTILSRSPELFFRTSSDGVIETRPMKGTQPRSLDPREDSRRRDFLRSDE
CCCCEEECCCCCHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCC
KNRAENLMIVDLLRNDISRVSETGSVHVPELFAVESYATVHQMVSLVRARLKAGCGLADI
CHHHCCEEHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
FAALYPCGSITGAPKIRAMEILAELEPGARDIYCGTIGWAAPDGRSEFNVSIRTMMLEGD
HHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCEEEEEEEEEEECC
AATFNVGGGLVWDSTSASEYEEALWKARFAQVTTPISA
CEEEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]