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The map label for this gene is fabH [H]

Identifier: 99080469

GI number: 99080469

Start: 665754

End: 666878

Strand: Reverse

Name: fabH [H]

Synonym: TM1040_0628

Alternate gene names: 99080469

Gene position: 666878-665754 (Counterclockwise)

Preceding gene: 99080473

Following gene: 99080467

Centisome position: 20.83

GC content: 59.11

Gene sequence:

>1125_bases
ATGTACACAGCAGCAATTACCGGCACCGGGGTGTACACCCCGTCCGAACGCATCACCAATGCAGAACTGGTCAAGGCCTT
TAACGCCTATGTCGACCTGCAGAATGAGAAACACGCCGACGAGATCGCCTCGGGCGCGCGCGAGCCGCTGCAATACTCAT
CCGAGGAGTTCATCCTCAAGGCCTCAGGCATTGAGAGCCGTTTTGTCATGGACAAATCCGGCGTCCTCGACCCGGAGGTG
ATGCACCCGCTCCTGCGCCAGCGCAGCGATGACGAACCCGGGATCATGGCCGAAATGGCGGTTGATGCCGCCAGACAGGC
TCTCGCGCAGGCAGGAAAATCGGCTGAGGATGTGGATCTGGTAATCTGTGCCGCCTCCAATATGGAGCGCGCCTATCCTG
CGGTGGCCATCGAGATCCAGCAGCTTCTCGGCATCCGGGGCTTTGCCTTTGACATGAACGTTGCCTGTTCCTCGGCCACC
TTTGGCATTCAGACCGCCGCCGACATGATCCGCTCGGGTTCCATTCGTGCAGCTCTTGTGGTCAATCCCGAAATCTGTTC
CGGCCACCTAGAGTGGCGCGACCGCGATTGCCACTTCATTTTTGGGGATGTTGCGACCGCCACCTTGATCGAGCGCAGCG
AAGACGCCACAAGCGCCCATTTCGAGATCCTCTCCACCCGTTGCGCCACAGAGTTCTCCAACAACATCCGCAACAACAAC
GGCTACCTGCGCCGCTCGCGCCCCGATGGCGTTGCGGACCGTCGTGACATGCAGTTCATGCAAAACGGTCGCAAGGTGTT
CAAGGAAGTGCTGCCAATGGTCAGCCAGCACATCACCGATCATATGACCGCTGAAGGTGTCGGCGCTGCCGACCTTAAAC
GGCTCTGGCTGCATCAGGCCAACAAGACGATGAATGATTTCATCGGTAAAAAGGTTCTGGGTCGCACGCCAGAGGCCGGA
GAACAGCCCAATATCCTGCAAGACTATGCCAACACCTCTTCGGCCGGCTCGATCATTGCGTTTTCAAAATTCTCGGACGA
TCTCGAGGCGGGCGACACGGGCCTGATCTGCTCTTTTGGGGCGGGCTACTCGGTGGGCTCAGTGCTCGTGCGGCGCCACG
GCTGA

Upstream 100 bases:

>100_bases
GATCTTGCGACTGCCCTTGACCTTCGCGAGGTAAACGGGCCCTATATGCGCCACCTTGAGACAGGGCCCTAGGGATGGGC
CTGCGACCCGGGACGTTACA

Downstream 100 bases:

>100_bases
GGCGATCCATCCTCCGGGCCCTTCTGGCCAAACCAAAACGCGCGCCCGAATGGGGCGCGCGGCTCAAGATCCTCGATACA
CATGGCCCCTGCAAAAAGGC

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MYTAAITGTGVYTPSERITNAELVKAFNAYVDLQNEKHADEIASGAREPLQYSSEEFILKASGIESRFVMDKSGVLDPEV
MHPLLRQRSDDEPGIMAEMAVDAARQALAQAGKSAEDVDLVICAASNMERAYPAVAIEIQQLLGIRGFAFDMNVACSSAT
FGIQTAADMIRSGSIRAALVVNPEICSGHLEWRDRDCHFIFGDVATATLIERSEDATSAHFEILSTRCATEFSNNIRNNN
GYLRRSRPDGVADRRDMQFMQNGRKVFKEVLPMVSQHITDHMTAEGVGAADLKRLWLHQANKTMNDFIGKKVLGRTPEAG
EQPNILQDYANTSSAGSIIAFSKFSDDLEAGDTGLICSFGAGYSVGSVLVRRHG

Sequences:

>Translated_374_residues
MYTAAITGTGVYTPSERITNAELVKAFNAYVDLQNEKHADEIASGAREPLQYSSEEFILKASGIESRFVMDKSGVLDPEV
MHPLLRQRSDDEPGIMAEMAVDAARQALAQAGKSAEDVDLVICAASNMERAYPAVAIEIQQLLGIRGFAFDMNVACSSAT
FGIQTAADMIRSGSIRAALVVNPEICSGHLEWRDRDCHFIFGDVATATLIERSEDATSAHFEILSTRCATEFSNNIRNNN
GYLRRSRPDGVADRRDMQFMQNGRKVFKEVLPMVSQHITDHMTAEGVGAADLKRLWLHQANKTMNDFIGKKVLGRTPEAG
EQPNILQDYANTSSAGSIIAFSKFSDDLEAGDTGLICSFGAGYSVGSVLVRRHG
>Mature_374_residues
MYTAAITGTGVYTPSERITNAELVKAFNAYVDLQNEKHADEIASGAREPLQYSSEEFILKASGIESRFVMDKSGVLDPEV
MHPLLRQRSDDEPGIMAEMAVDAARQALAQAGKSAEDVDLVICAASNMERAYPAVAIEIQQLLGIRGFAFDMNVACSSAT
FGIQTAADMIRSGSIRAALVVNPEICSGHLEWRDRDCHFIFGDVATATLIERSEDATSAHFEILSTRCATEFSNNIRNNN
GYLRRSRPDGVADRRDMQFMQNGRKVFKEVLPMVSQHITDHMTAEGVGAADLKRLWLHQANKTMNDFIGKKVLGRTPEAG
EQPNILQDYANTSSAGSIIAFSKFSDDLEAGDTGLICSFGAGYSVGSVLVRRHG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=377, Percent_Identity=27.0557029177719, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 40811; Mature: 40811

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTAAITGTGVYTPSERITNAELVKAFNAYVDLQNEKHADEIASGAREPLQYSSEEFILK
CEEEEEECCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHCCCCCEEEE
ASGIESRFVMDKSGVLDPEVMHPLLRQRSDDEPGIMAEMAVDAARQALAQAGKSAEDVDL
ECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
VICAASNMERAYPAVAIEIQQLLGIRGFAFDMNVACSSATFGIQTAADMIRSGSIRAALV
EEEECCCCCHHCCHHHEEHHHHHCCCCEEEECCEEECCCCCCHHHHHHHHHCCCCEEEEE
VNPEICSGHLEWRDRDCHFIFGDVATATLIERSEDATSAHFEILSTRCATEFSNNIRNNN
ECHHHHCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GYLRRSRPDGVADRRDMQFMQNGRKVFKEVLPMVSQHITDHMTAEGVGAADLKRLWLHQA
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NKTMNDFIGKKVLGRTPEAGEQPNILQDYANTSSAGSIIAFSKFSDDLEAGDTGLICSFG
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEECC
AGYSVGSVLVRRHG
CCCCHHHHHHHCCC
>Mature Secondary Structure
MYTAAITGTGVYTPSERITNAELVKAFNAYVDLQNEKHADEIASGAREPLQYSSEEFILK
CEEEEEECCCCCCCHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCHHHCCCCCEEEE
ASGIESRFVMDKSGVLDPEVMHPLLRQRSDDEPGIMAEMAVDAARQALAQAGKSAEDVDL
ECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEE
VICAASNMERAYPAVAIEIQQLLGIRGFAFDMNVACSSATFGIQTAADMIRSGSIRAALV
EEEECCCCCHHCCHHHEEHHHHHCCCCEEEECCEEECCCCCCHHHHHHHHHCCCCEEEEE
VNPEICSGHLEWRDRDCHFIFGDVATATLIERSEDATSAHFEILSTRCATEFSNNIRNNN
ECHHHHCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
GYLRRSRPDGVADRRDMQFMQNGRKVFKEVLPMVSQHITDHMTAEGVGAADLKRLWLHQA
CEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
NKTMNDFIGKKVLGRTPEAGEQPNILQDYANTSSAGSIIAFSKFSDDLEAGDTGLICSFG
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEECC
AGYSVGSVLVRRHG
CCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA