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The map label for this gene is tdk [H]

Identifier: 99080467

GI number: 99080467

Start: 664038

End: 664640

Strand: Reverse

Name: tdk [H]

Synonym: TM1040_0626

Alternate gene names: 99080467

Gene position: 664640-664038 (Counterclockwise)

Preceding gene: 99080469

Following gene: 99080461

Centisome position: 20.76

GC content: 59.87

Gene sequence:

>603_bases
ATGGCCAAGCTCTATTTCAACTACTCGACCATGAACGCCGGCAAGTCCACGGTCCTGCTGCAAGCGTCTCATAACTATCG
CGAGAACAACATGCAGACCTACCTGCTGACCGCGCGCATCGACGACCGCGCCGGAACGGGTCGGATTGCCTCACGCATTG
GCATCAGCGCAGAGGCAGATATGTTTGCGCCCGAAGATGACCTCTTTGGCAAAATCGAAACCCGCCTCAAGGATGGGCCT
GTGGCGGCGATCTTTGTGGATGAGGCGCAGTTTCTGACGCACGAGCAGGTCTGGCAGCTGGCCCGCGTCGTCGATGATCT
GGGTGTGCCGGTGCTGGCCTTCGGGCTTCGTGTGGATTTTCAGGGCAATCTGTTTCCCGGCTCTGCAAGCCTGCTGGCCC
TTGCCGACGAGATGCGCGAAGTGCGCACCATCTGCCATTGCGGCAAAAAAGCAACCATGGTGGTGCGTCAGGACGCGACA
GGCCAGGTCCTGACCGAAGGGGACCAGGTACAGATTGGCGGCAACGAATCTTATATCTCCTTGTGCCGCCGCCACTGGCG
CGCCGCGATGGGGGATCTCCCCACCGCTAAAACACTGGGATAG

Upstream 100 bases:

>100_bases
CATGCCCCTTGGCCTGCCCCACCCAAGGTCTGGCTGACCCAACTTCGCCCACCGCGCTTTCGTCTTTTCTAGAGCCAGCA
AACGGGATAGACCGCAGCGC

Downstream 100 bases:

>100_bases
AGCATCTTCTTCTAACCGCAAATATCCCGGGGTGAATGGGCCCCTTGTGGGCCCAGAGGGGCAGTGCCCCTGCCTTCACG
AGATCTCCCTCGCGCCTGGT

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MAKLYFNYSTMNAGKSTVLLQASHNYRENNMQTYLLTARIDDRAGTGRIASRIGISAEADMFAPEDDLFGKIETRLKDGP
VAAIFVDEAQFLTHEQVWQLARVVDDLGVPVLAFGLRVDFQGNLFPGSASLLALADEMREVRTICHCGKKATMVVRQDAT
GQVLTEGDQVQIGGNESYISLCRRHWRAAMGDLPTAKTLG

Sequences:

>Translated_200_residues
MAKLYFNYSTMNAGKSTVLLQASHNYRENNMQTYLLTARIDDRAGTGRIASRIGISAEADMFAPEDDLFGKIETRLKDGP
VAAIFVDEAQFLTHEQVWQLARVVDDLGVPVLAFGLRVDFQGNLFPGSASLLALADEMREVRTICHCGKKATMVVRQDAT
GQVLTEGDQVQIGGNESYISLCRRHWRAAMGDLPTAKTLG
>Mature_199_residues
AKLYFNYSTMNAGKSTVLLQASHNYRENNMQTYLLTARIDDRAGTGRIASRIGISAEADMFAPEDDLFGKIETRLKDGPV
AAIFVDEAQFLTHEQVWQLARVVDDLGVPVLAFGLRVDFQGNLFPGSASLLALADEMREVRTICHCGKKATMVVRQDATG
QVLTEGDQVQIGGNESYISLCRRHWRAAMGDLPTAKTLG

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Escherichia coli, GI1787490, Length=190, Percent_Identity=52.6315789473684, Blast_Score=221, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22013; Mature: 21882

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00603 TK_CELLULAR_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLYFNYSTMNAGKSTVLLQASHNYRENNMQTYLLTARIDDRAGTGRIASRIGISAEAD
CEEEEEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCC
MFAPEDDLFGKIETRLKDGPVAAIFVDEAQFLTHEQVWQLARVVDDLGVPVLAFGLRVDF
CCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
QGNLFPGSASLLALADEMREVRTICHCGKKATMVVRQDATGQVLTEGDQVQIGGNESYIS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCEEEECCCHHHHH
LCRRHWRAAMGDLPTAKTLG
HHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AKLYFNYSTMNAGKSTVLLQASHNYRENNMQTYLLTARIDDRAGTGRIASRIGISAEAD
EEEEEEEEECCCCCEEEEEEECCCCCCCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCC
MFAPEDDLFGKIETRLKDGPVAAIFVDEAQFLTHEQVWQLARVVDDLGVPVLAFGLRVDF
CCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEE
QGNLFPGSASLLALADEMREVRTICHCGKKATMVVRQDATGQVLTEGDQVQIGGNESYIS
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCEEEECCCHHHHH
LCRRHWRAAMGDLPTAKTLG
HHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA