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The map label for this gene is lrp [H]

Identifier: 99080456

GI number: 99080456

Start: 655592

End: 656092

Strand: Direct

Name: lrp [H]

Synonym: TM1040_0615

Alternate gene names: 99080456

Gene position: 655592-656092 (Clockwise)

Preceding gene: 99080452

Following gene: 99080458

Centisome position: 20.48

GC content: 61.68

Gene sequence:

>501_bases
ATGGTCACCACACGTCTGGACCCGATCGACCGCAAGATTCTGTCGGAGCTACAGGCCGATGGCCGGATGACGAATGTCGA
ACTGGCCAAGCGCGTCGGAATTTCTGCGCCCCCCTGCCTGCGGCGGGTGCGCGCCTTGGAGGAGGCGGGTTTGATCCGGG
GCTACCACGCGGAGGTGAACGACCGCGAGTTGGGCTTTGAGGTGCAGGTCTTTGCGATGGTGGGCCTCGAAAGCCAGGCC
GAAGCGGAACTCAGTGCCTTTGAAGAAAAATGCCGCAGTTGGCCCTTGGTTCGGGAATGCCACATGCTGAATGGCGAGGT
GGATTTCATCCTGAAGTGCGTGGCGCCGGACCTGTCGACGTTCCAGAGCTTTTTGACCAGCGATCTGCTGACCACGCCCA
ATGTGGCGAGCGTCAAGACGTCGCTGGTTATCCGGGGTGCCAAGGATGAGCCAGGCGTGCCCTTTGACGTGCTTGAAGAG
CGGCTCGCGCGCGAAGCCTGA

Upstream 100 bases:

>100_bases
TCCGAAGATCGCTACAAGAATGTTGCTAGGTTGTGAAATAATGTTGCGTGATTGCCGGCCTCTGCTATAAGAAACGCAAT
TCTCAGGAGAAAGCCTACCC

Downstream 100 bases:

>100_bases
GCACGGCGGAACCCGCGCTCAAGACCTCAGTCAGGCTTGCGTGGTGCGCGCGCGATCAAAGGCGAGCGGGCCAAAATCCG
AAATCTTGTCGGCATGTGGA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MVTTRLDPIDRKILSELQADGRMTNVELAKRVGISAPPCLRRVRALEEAGLIRGYHAEVNDRELGFEVQVFAMVGLESQA
EAELSAFEEKCRSWPLVRECHMLNGEVDFILKCVAPDLSTFQSFLTSDLLTTPNVASVKTSLVIRGAKDEPGVPFDVLEE
RLAREA

Sequences:

>Translated_166_residues
MVTTRLDPIDRKILSELQADGRMTNVELAKRVGISAPPCLRRVRALEEAGLIRGYHAEVNDRELGFEVQVFAMVGLESQA
EAELSAFEEKCRSWPLVRECHMLNGEVDFILKCVAPDLSTFQSFLTSDLLTTPNVASVKTSLVIRGAKDEPGVPFDVLEE
RLAREA
>Mature_166_residues
MVTTRLDPIDRKILSELQADGRMTNVELAKRVGISAPPCLRRVRALEEAGLIRGYHAEVNDRELGFEVQVFAMVGLESQA
EAELSAFEEKCRSWPLVRECHMLNGEVDFILKCVAPDLSTFQSFLTSDLLTTPNVASVKTSLVIRGAKDEPGVPFDVLEE
RLAREA

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=41.958041958042, Blast_Score=119, Evalue=8e-29,
Organism=Escherichia coli, GI87081742, Length=151, Percent_Identity=23.841059602649, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1790182, Length=140, Percent_Identity=26.4285714285714, Blast_Score=63, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18458; Mature: 18458

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTTRLDPIDRKILSELQADGRMTNVELAKRVGISAPPCLRRVRALEEAGLIRGYHAEVN
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
DRELGFEVQVFAMVGLESQAEAELSAFEEKCRSWPLVRECHMLNGEVDFILKCVAPDLST
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCHHH
FQSFLTSDLLTTPNVASVKTSLVIRGAKDEPGVPFDVLEERLAREA
HHHHHHHHHCCCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MVTTRLDPIDRKILSELQADGRMTNVELAKRVGISAPPCLRRVRALEEAGLIRGYHAEVN
CCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
DRELGFEVQVFAMVGLESQAEAELSAFEEKCRSWPLVRECHMLNGEVDFILKCVAPDLST
CCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCCCHHH
FQSFLTSDLLTTPNVASVKTSLVIRGAKDEPGVPFDVLEERLAREA
HHHHHHHHHCCCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]