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The map label for this gene is cyaA [H]

Identifier: 99080454

GI number: 99080454

Start: 652460

End: 654220

Strand: Reverse

Name: cyaA [H]

Synonym: TM1040_0613

Alternate gene names: 99080454

Gene position: 654220-652460 (Counterclockwise)

Preceding gene: 99080455

Following gene: 99080453

Centisome position: 20.44

GC content: 60.42

Gene sequence:

>1761_bases
ATGTTCCCGCAAGGTGTTACAGAGGCGACATGCGCGCCGCCCCTCCAATGCAAGAAGGACAGCTCGCTCTTGGCCCAAGC
ACTCTGGCAAGGCAACTGGATCCACCGCAGCCGGCTGGTCTCCGGCCTTGTGCTTTTTACTTTTGCATTCTTTCACTTTC
TGAATGTTGCCGCCGGTCTGGTCTCGCCCGCGCTGATGGAGGCGATGCAGGAGGTGCGCGAACCTTTCAGCAAAAGCCCC
CCCGGTCAGGTGCTTCTGTACGGGTCGCTTTTGGTGCATGCCGGTCTAGCACTCTGGCAGGTGGCGATGCGGCGCACACT
GCGGATGAGCTTTGTGCAGGGATTGCAATTGCTTCTTGGGGTACTGATCCCGCTGCAATTGTTTCAACATATTGCGCACA
CGAACTACGCCGCCCGCGTGCAAGGCTATGAGGACGAAATGTCCTCGGTCGTGGTGATGCTATGGTCAGGGCCGGAAGCG
CTGCACCAGTATCTCCTGCTGCTGGCGGTATGGATACATGGCTGCGTCGGCCTTCACATGTGGCTGCGCCTGACAAGATG
GTGGGGGACCCTGACACCCTATATGATCGGGCTTGCGGTCTTGATCCCCGCGCTGGCCCTAGCCGGTTTGGTGACTGAAG
GGCGCCGCATGTGGGCGTTCTTTTCAAACCCTGAGGTCGCGCAACAAATCATCGAGGATTACAACTGGCCGGATGCCGCG
GGTTTTGCCCATCTGGCGATGGTCTCCGACTATAGCATCTCGATCTTTTTTGGCTGTCTCGTGCTCGCCCTGGGCACCTA
TGGGGTGAGGCGCCTCATTCGGCGTCGTCGATCGGTGCGCATCACCTACGAGCGTGGTCCCGAGGTGACGGCCGACCGCG
GGCTGACCGTGCTGGAAATCTCGCAAATGAATGGCATTGCGCACCCTTCGCTTTGTGGCGGCAAAGGGCGCTGCACGACC
TGCCGCGTGGCAATTCTGGCGGGGGGCGACGATCTCCCCCCACCGACAGCGGCTGAGGCCCGCAGTTTGCGCGCCATCAA
CGCGCCCGAGAACATGCGTCTGGCATGCCAGATCACGCCCACCTCGGCTTTGACGGTCAAGCGTCTCTATATGGCAAAGG
GCCGTCATCAGGTTCACGCAACCCAAGGCGAAGAAAAAACCATCGCGGTGCTGTTTCTCGACATTCGTGGTTTTACCGCG
CGGTCCGAGGGGCTCTTGCCCTATGATGTTGTGTTCCTGCTCAACCGGTTTTTTGACGCCATTGTCCCGCAAATCACACG
CGCTGGCGGGGCCGTCGACAAATATATGGGGGATGGGTTGCTCGCTCTGTTTGAAACCTCGGATGCCACCAGTTCGGCAC
AGGCCGCGCTGACAGCGGCAGCCGACATTGGTTCCGCGCTGGAGCGGTTCAATCGCCTGCTGGTCGCCGAAGGAGAACAG
CCATTGCGCATCGGCATGGGGGTTCACACCGGAACCGTCGTTCTGGGTGAAATCGGTGCAGCCGGGCATGCGCCCCGTAC
GCTCATTGGTGCCACTGTCAATGCCGCAAGCCGCCTTGAGGCCAAGACCAAGGAGCTCGGCGTCGAAATCCTCATTTCGC
GCGCAGTCTTCGACACCGCAACCCTGCCCCAAGCTGAGACACGGTTTCAAACCTTCGAGCTGCGTGGCGTGGATGCCCCG
GTTGCGGCCCTGCCCCTTGAGCATGCATCAAGGCTGAGTGACTTGTTGGCAGACACTCCCTCGGAGAACGCCCTTCGGTA
A

Upstream 100 bases:

>100_bases
TTGCGAACTAATACGCAGCCAGGCGGACAGCGCGCCCTGCGCAGCACCATTCTAGGGTCGCAACCACCGGTATCATGAGA
AGGGCTTGTCGGCGGGCGGC

Downstream 100 bases:

>100_bases
CATCGGCGCGAATGAACCATCCAACCCTGAGCGCGCAACGGTGAATTCTGTTCCAAAACCGGGCCCGTTTGCATGACCCG
TGATTGAAACACGTCACATT

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MFPQGVTEATCAPPLQCKKDSSLLAQALWQGNWIHRSRLVSGLVLFTFAFFHFLNVAAGLVSPALMEAMQEVREPFSKSP
PGQVLLYGSLLVHAGLALWQVAMRRTLRMSFVQGLQLLLGVLIPLQLFQHIAHTNYAARVQGYEDEMSSVVVMLWSGPEA
LHQYLLLLAVWIHGCVGLHMWLRLTRWWGTLTPYMIGLAVLIPALALAGLVTEGRRMWAFFSNPEVAQQIIEDYNWPDAA
GFAHLAMVSDYSISIFFGCLVLALGTYGVRRLIRRRRSVRITYERGPEVTADRGLTVLEISQMNGIAHPSLCGGKGRCTT
CRVAILAGGDDLPPPTAAEARSLRAINAPENMRLACQITPTSALTVKRLYMAKGRHQVHATQGEEKTIAVLFLDIRGFTA
RSEGLLPYDVVFLLNRFFDAIVPQITRAGGAVDKYMGDGLLALFETSDATSSAQAALTAAADIGSALERFNRLLVAEGEQ
PLRIGMGVHTGTVVLGEIGAAGHAPRTLIGATVNAASRLEAKTKELGVEILISRAVFDTATLPQAETRFQTFELRGVDAP
VAALPLEHASRLSDLLADTPSENALR

Sequences:

>Translated_586_residues
MFPQGVTEATCAPPLQCKKDSSLLAQALWQGNWIHRSRLVSGLVLFTFAFFHFLNVAAGLVSPALMEAMQEVREPFSKSP
PGQVLLYGSLLVHAGLALWQVAMRRTLRMSFVQGLQLLLGVLIPLQLFQHIAHTNYAARVQGYEDEMSSVVVMLWSGPEA
LHQYLLLLAVWIHGCVGLHMWLRLTRWWGTLTPYMIGLAVLIPALALAGLVTEGRRMWAFFSNPEVAQQIIEDYNWPDAA
GFAHLAMVSDYSISIFFGCLVLALGTYGVRRLIRRRRSVRITYERGPEVTADRGLTVLEISQMNGIAHPSLCGGKGRCTT
CRVAILAGGDDLPPPTAAEARSLRAINAPENMRLACQITPTSALTVKRLYMAKGRHQVHATQGEEKTIAVLFLDIRGFTA
RSEGLLPYDVVFLLNRFFDAIVPQITRAGGAVDKYMGDGLLALFETSDATSSAQAALTAAADIGSALERFNRLLVAEGEQ
PLRIGMGVHTGTVVLGEIGAAGHAPRTLIGATVNAASRLEAKTKELGVEILISRAVFDTATLPQAETRFQTFELRGVDAP
VAALPLEHASRLSDLLADTPSENALR
>Mature_586_residues
MFPQGVTEATCAPPLQCKKDSSLLAQALWQGNWIHRSRLVSGLVLFTFAFFHFLNVAAGLVSPALMEAMQEVREPFSKSP
PGQVLLYGSLLVHAGLALWQVAMRRTLRMSFVQGLQLLLGVLIPLQLFQHIAHTNYAARVQGYEDEMSSVVVMLWSGPEA
LHQYLLLLAVWIHGCVGLHMWLRLTRWWGTLTPYMIGLAVLIPALALAGLVTEGRRMWAFFSNPEVAQQIIEDYNWPDAA
GFAHLAMVSDYSISIFFGCLVLALGTYGVRRLIRRRRSVRITYERGPEVTADRGLTVLEISQMNGIAHPSLCGGKGRCTT
CRVAILAGGDDLPPPTAAEARSLRAINAPENMRLACQITPTSALTVKRLYMAKGRHQVHATQGEEKTIAVLFLDIRGFTA
RSEGLLPYDVVFLLNRFFDAIVPQITRAGGAVDKYMGDGLLALFETSDATSSAQAALTAAADIGSALERFNRLLVAEGEQ
PLRIGMGVHTGTVVLGEIGAAGHAPRTLIGATVNAASRLEAKTKELGVEILISRAVFDTATLPQAETRFQTFELRGVDAP
VAALPLEHASRLSDLLADTPSENALR

Specific function: Unknown

COG id: COG0633

COG function: function code C; Ferredoxin

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 63828; Mature: 63828

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50125 GUANYLATE_CYCLASES_2 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPQGVTEATCAPPLQCKKDSSLLAQALWQGNWIHRSRLVSGLVLFTFAFFHFLNVAAGL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSPALMEAMQEVREPFSKSPPGQVLLYGSLLVHAGLALWQVAMRRTLRMSFVQGLQLLLG
HHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIPLQLFQHIAHTNYAARVQGYEDEMSSVVVMLWSGPEALHQYLLLLAVWIHGCVGLHM
HHHHHHHHHHHHHCCHHHEECCCHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
WLRLTRWWGTLTPYMIGLAVLIPALALAGLVTEGRRMWAFFSNPEVAQQIIEDYNWPDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCC
GFAHLAMVSDYSISIFFGCLVLALGTYGVRRLIRRRRSVRITYERGPEVTADRGLTVLEI
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEE
SQMNGIAHPSLCGGKGRCTTCRVAILAGGDDLPPPTAAEARSLRAINAPENMRLACQITP
HHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHCEEECCCCCCEEEEEECC
TSALTVKRLYMAKGRHQVHATQGEEKTIAVLFLDIRGFTARSEGLLPYDVVFLLNRFFDA
CHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
IVPQITRAGGAVDKYMGDGLLALFETSDATSSAQAALTAAADIGSALERFNRLLVAEGEQ
HHHHHHHCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
PLRIGMGVHTGTVVLGEIGAAGHAPRTLIGATVNAASRLEAKTKELGVEILISRAVFDTA
CEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TLPQAETRFQTFELRGVDAPVAALPLEHASRLSDLLADTPSENALR
CCCCHHHHHEEEEECCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFPQGVTEATCAPPLQCKKDSSLLAQALWQGNWIHRSRLVSGLVLFTFAFFHFLNVAAGL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSPALMEAMQEVREPFSKSPPGQVLLYGSLLVHAGLALWQVAMRRTLRMSFVQGLQLLLG
HHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLIPLQLFQHIAHTNYAARVQGYEDEMSSVVVMLWSGPEALHQYLLLLAVWIHGCVGLHM
HHHHHHHHHHHHHCCHHHEECCCHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
WLRLTRWWGTLTPYMIGLAVLIPALALAGLVTEGRRMWAFFSNPEVAQQIIEDYNWPDAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCC
GFAHLAMVSDYSISIFFGCLVLALGTYGVRRLIRRRRSVRITYERGPEVTADRGLTVLEI
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEEEE
SQMNGIAHPSLCGGKGRCTTCRVAILAGGDDLPPPTAAEARSLRAINAPENMRLACQITP
HHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHCEEECCCCCCEEEEEECC
TSALTVKRLYMAKGRHQVHATQGEEKTIAVLFLDIRGFTARSEGLLPYDVVFLLNRFFDA
CHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
IVPQITRAGGAVDKYMGDGLLALFETSDATSSAQAALTAAADIGSALERFNRLLVAEGEQ
HHHHHHHCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCC
PLRIGMGVHTGTVVLGEIGAAGHAPRTLIGATVNAASRLEAKTKELGVEILISRAVFDTA
CEEEECCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TLPQAETRFQTFELRGVDAPVAALPLEHASRLSDLLADTPSENALR
CCCCHHHHHEEEEECCCCCCHHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]