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The map label for this gene is pitA [C]

Identifier: 99080449

GI number: 99080449

Start: 647574

End: 649058

Strand: Reverse

Name: pitA [C]

Synonym: TM1040_0608

Alternate gene names: 99080449

Gene position: 649058-647574 (Counterclockwise)

Preceding gene: 99080450

Following gene: 99080448

Centisome position: 20.28

GC content: 59.33

Gene sequence:

>1485_bases
GTGTCCCAAAACGATCTAGAGCCGCGTCACCTTGAAACCCTGGACCGCGACCTTGATCGCCTGTCCTCGCTGGAACAGGC
GACAGCCTATGTGGGGCGGTCGAATGTCGGGCTTGGTCTCGCCTTCATGTTCATCCTGATCGTCGCTGCAGCGACCGGAT
TGATGCTCGGCAGTGCCGACAACACGTTTATCATCGTGATCGCCGCCGCCTTTGGCGCCTATATGGCGCTCAATATTGGG
GCCAATGATGTGGCCAACAACATGGGTCCTGCGGTTGGGGCAAACGCCATGTCGATGGGCTTTGCCATCGTGGTTGCGGC
CATCTTTGAGAGCGCGGGCGCCCTGATTGCGGGCGGAGATGTGGTTTCGACCATCGCCAAAGGGATCATCTCGCCCGATA
CCATGGCGACCTCTTCGATGTTCATCGCCGCTATGCTTGCCGCCCTTCTGGCCTCGGCACTCTGGGTCAACCTTGCAACC
TGGATCGGTGCACCTGTTTCCACCACGCATGCGGTTGTAGGGGGCGTCATGGGCGCCGGGATCGCGGCCGCCGGTTTTGC
CGCCGTGAACTGGAGTAAAATGAGCGCAATCGCCGCCAGCTGGGTGATCTCGCCGCTCTTGGGTGGACTGATCGCGGCCG
GGTTCCTGTGGCTCATCAAGTCGCGCATCATCTACCGCGAAGACAAGATTTCTGCAGCGCGCACCTGGGTCCCCATTCTG
GTGGGCATCATGGCGGGAGCATTCGCCTCTTACCTCGCGGTCAAAGGCCTGAAAAAGCTCATCAAAATTGACCTCTCGCA
TTCACTGATGATTGGTCTTGTGGTTGCGCTTCTGGTCTGGATGCTCATGATCCCCGTGATCCGCAAACAGTCGAAGGGAT
TGGAGAACAGAAACAAATCGCTGAAGGTGCTCTTCTCGATCCCACTGATTGTCTCGGCGGCCCTGCTGAGCTTTGCGCAT
GGTGCAAACGATGTGGCAAACGCGGTTGGACCGCTTGCGGCAATCGTGCAGGCGTCGACCTCTGGGGATTTCACCCATGC
AGTCTCAATCCCTTTCTGGGTGATGATTATCGGGGCCTTCGGGATTTCCTTTGGTCTCTTCCTGTTTGGCCCCAAACTGA
TCCGCATGGTGGGCAGCCAGATCACCAAACTGAACCCGATGCGGGCATATTGCGTGGCGCTGTCTGCGGCCATCACGGTG
ATCGTGGCAAGCTGGCTCGGCCTTCCGGTGAGCTCCACACATATCGCGATTGGCGGCGTCTTTGGCGTTGGATTCTTCCG
CGAATGGGACACAGAGCGCCGCATGCGCAAGTCTAAGGCCGTCAAGGCAGATGCGCCCAACGTAGGCCCCGAAGAGCGCC
GCCGCCGCAAACTGGTGCGACGCTCACATTTCCTGACCATCATCGCGGCCTGGGTCATCACCGTCCCCGCTGCCGCGACG
CTCTCTGGGGTGTTGTTCGTGCTGATCAACCGGATGGTGGGATAA

Upstream 100 bases:

>100_bases
GGATCAACAGGAACTCCTTCAGGGCAAGGCGGCATATACGTTGCCCGGGTGTCACAAAACCGTTACAGACGCGGCGCGCA
AAAACGAATGGAGAGGACGG

Downstream 100 bases:

>100_bases
GTCCCCCCTTCCCCATCGATTTTGATGCGGCCCGCCCCACTGGCGGGTCGTTTTCTTTTCAGGTCAGGCTTCCTATGATC
GCATTCAACAGGAGCACATA

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSQNDLEPRHLETLDRDLDRLSSLEQATAYVGRSNVGLGLAFMFILIVAAATGLMLGSADNTFIIVIAAAFGAYMALNIG
ANDVANNMGPAVGANAMSMGFAIVVAAIFESAGALIAGGDVVSTIAKGIISPDTMATSSMFIAAMLAALLASALWVNLAT
WIGAPVSTTHAVVGGVMGAGIAAAGFAAVNWSKMSAIAASWVISPLLGGLIAAGFLWLIKSRIIYREDKISAARTWVPIL
VGIMAGAFASYLAVKGLKKLIKIDLSHSLMIGLVVALLVWMLMIPVIRKQSKGLENRNKSLKVLFSIPLIVSAALLSFAH
GANDVANAVGPLAAIVQASTSGDFTHAVSIPFWVMIIGAFGISFGLFLFGPKLIRMVGSQITKLNPMRAYCVALSAAITV
IVASWLGLPVSSTHIAIGGVFGVGFFREWDTERRMRKSKAVKADAPNVGPEERRRRKLVRRSHFLTIIAAWVITVPAAAT
LSGVLFVLINRMVG

Sequences:

>Translated_494_residues
MSQNDLEPRHLETLDRDLDRLSSLEQATAYVGRSNVGLGLAFMFILIVAAATGLMLGSADNTFIIVIAAAFGAYMALNIG
ANDVANNMGPAVGANAMSMGFAIVVAAIFESAGALIAGGDVVSTIAKGIISPDTMATSSMFIAAMLAALLASALWVNLAT
WIGAPVSTTHAVVGGVMGAGIAAAGFAAVNWSKMSAIAASWVISPLLGGLIAAGFLWLIKSRIIYREDKISAARTWVPIL
VGIMAGAFASYLAVKGLKKLIKIDLSHSLMIGLVVALLVWMLMIPVIRKQSKGLENRNKSLKVLFSIPLIVSAALLSFAH
GANDVANAVGPLAAIVQASTSGDFTHAVSIPFWVMIIGAFGISFGLFLFGPKLIRMVGSQITKLNPMRAYCVALSAAITV
IVASWLGLPVSSTHIAIGGVFGVGFFREWDTERRMRKSKAVKADAPNVGPEERRRRKLVRRSHFLTIIAAWVITVPAAAT
LSGVLFVLINRMVG
>Mature_493_residues
SQNDLEPRHLETLDRDLDRLSSLEQATAYVGRSNVGLGLAFMFILIVAAATGLMLGSADNTFIIVIAAAFGAYMALNIGA
NDVANNMGPAVGANAMSMGFAIVVAAIFESAGALIAGGDVVSTIAKGIISPDTMATSSMFIAAMLAALLASALWVNLATW
IGAPVSTTHAVVGGVMGAGIAAAGFAAVNWSKMSAIAASWVISPLLGGLIAAGFLWLIKSRIIYREDKISAARTWVPILV
GIMAGAFASYLAVKGLKKLIKIDLSHSLMIGLVVALLVWMLMIPVIRKQSKGLENRNKSLKVLFSIPLIVSAALLSFAHG
ANDVANAVGPLAAIVQASTSGDFTHAVSIPFWVMIIGAFGISFGLFLFGPKLIRMVGSQITKLNPMRAYCVALSAAITVI
VASWLGLPVSSTHIAIGGVFGVGFFREWDTERRMRKSKAVKADAPNVGPEERRRRKLVRRSHFLTIIAAWVITVPAAATL
SGVLFVLINRMVG

Specific function: Potential transporter for phosphate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family [H]

Homologues:

Organism=Homo sapiens, GI31543630, Length=299, Percent_Identity=27.7591973244147, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI5803173, Length=244, Percent_Identity=29.9180327868852, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1789907, Length=266, Percent_Identity=27.4436090225564, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789360, Length=156, Percent_Identity=31.4102564102564, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146401, Length=488, Percent_Identity=27.2540983606557, Blast_Score=175, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32566716, Length=425, Percent_Identity=31.5294117647059, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI17557328, Length=464, Percent_Identity=24.3534482758621, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI71981576, Length=218, Percent_Identity=31.651376146789, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17539280, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536725, Length=456, Percent_Identity=21.4912280701754, Blast_Score=97, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319773, Length=142, Percent_Identity=34.5070422535211, Blast_Score=100, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21356511, Length=202, Percent_Identity=34.6534653465347, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 51917; Mature: 51786

Theoretical pI: Translated: 10.83; Mature: 10.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNDLEPRHLETLDRDLDRLSSLEQATAYVGRSNVGLGLAFMFILIVAAATGLMLGSAD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NTFIIVIAAAFGAYMALNIGANDVANNMGPAVGANAMSMGFAIVVAAIFESAGALIAGGD
CCEEEEEHHHHHHHHEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECHH
VVSTIAKGIISPDTMATSSMFIAAMLAALLASALWVNLATWIGAPVSTTHAVVGGVMGAG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IAAAGFAAVNWSKMSAIAASWVISPLLGGLIAAGFLWLIKSRIIYREDKISAARTWVPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIMAGAFASYLAVKGLKKLIKIDLSHSLMIGLVVALLVWMLMIPVIRKQSKGLENRNKS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LKVLFSIPLIVSAALLSFAHGANDVANAVGPLAAIVQASTSGDFTHAVSIPFWVMIIGAF
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
GISFGLFLFGPKLIRMVGSQITKLNPMRAYCVALSAAITVIVASWLGLPVSSTHIAIGGV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHH
FGVGFFREWDTERRMRKSKAVKADAPNVGPEERRRRKLVRRSHFLTIIAAWVITVPAAAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVLFVLINRMVG
HHHHHHHHHHHHCC
>Mature Secondary Structure 
SQNDLEPRHLETLDRDLDRLSSLEQATAYVGRSNVGLGLAFMFILIVAAATGLMLGSAD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
NTFIIVIAAAFGAYMALNIGANDVANNMGPAVGANAMSMGFAIVVAAIFESAGALIAGGD
CCEEEEEHHHHHHHHEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEECHH
VVSTIAKGIISPDTMATSSMFIAAMLAALLASALWVNLATWIGAPVSTTHAVVGGVMGAG
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
IAAAGFAAVNWSKMSAIAASWVISPLLGGLIAAGFLWLIKSRIIYREDKISAARTWVPIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGIMAGAFASYLAVKGLKKLIKIDLSHSLMIGLVVALLVWMLMIPVIRKQSKGLENRNKS
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
LKVLFSIPLIVSAALLSFAHGANDVANAVGPLAAIVQASTSGDFTHAVSIPFWVMIIGAF
EEHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHH
GISFGLFLFGPKLIRMVGSQITKLNPMRAYCVALSAAITVIVASWLGLPVSSTHIAIGGV
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHH
FGVGFFREWDTERRMRKSKAVKADAPNVGPEERRRRKLVRRSHFLTIIAAWVITVPAAAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVLFVLINRMVG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]