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The map label for this gene is frpC [H]

Identifier: 99080409

GI number: 99080409

Start: 604197

End: 605432

Strand: Reverse

Name: frpC [H]

Synonym: TM1040_0568

Alternate gene names: 99080409

Gene position: 605432-604197 (Counterclockwise)

Preceding gene: 99080410

Following gene: 99080408

Centisome position: 18.91

GC content: 55.34

Gene sequence:

>1236_bases
ATGGCGATTTTAACTTCAAGCGACTCAATTGACGCGATCTTATTTCCAAGCACCTTCATTTCCGGTGGATACATTTTCCC
AACGCCTGTCTACAGATATGATGTGACTGACAGCTACATTTCCTACACGCTTGACCAAACGCGCGGCTCGACCGGCTATT
ACAACATAAACCCAACTGTTCGGATATTTGGGGACAATCTCAGTGTCGACTCGTCTGGGCGTGCGTCAGGCACGATCACC
GCGATGGAGTTTCGCTCTTCTAATCGGGGCGAGATCGCACGCATTGAGCAGATCAGCATCAATGCATCCGATTTCACGGA
CATCATTTTCGCACGGATCTCCGGAGACAATACGTCAAGCACACAATTCGAGACCCTGCTGGCAGAGGCTTTGGACGTTC
TTGAATTTGGCAATCGCAACCAAGACATCTCTGACAGAGGCATGTTGCAGTATTTGAGCTTCATCGACCTGCAGGGAGGA
AACGACGAATTCCATCTCGCGCGCCCCAAAACTGACGGGACACGCACAATTGACGGCGGCGCGGGTCAGGACACGCTCCA
TCTTGATGACTTCGGCGTGCCCGACTCGTTTGTCGTGAACTTAAAGACAGGCCAGATCATCACCGACTCAACTTCGGTGA
ATATCACTGGCTTTGAGATCATTGACGGCAACCCCTTCGTCGATCGCTATATTGGTTCCAACAGCGGTGATCACATCAGA
GCAGCTGGTCGCGCCGATCAGATCAACGGGTTCGGGGGGCGCGACACCCTCTCTGGAGGATGGGGGGATGACAGGATCAC
GGGTGGCCGAGGCAAAGACAGACTTCATGGCGACGAAGGCAACGACTTTCTGCGCGGGGACGCGGGCGCAGATCTTCTTG
TTGGTGGCGCAGGGCGGGATCGCCTCGTCGGCCGCGCCGGGCAGGACACGCTCATCGCAGATGACGGGCGGGACCGCCTC
ATCGGCGGAGCGGGTTCGGACCTCTTCGTGTTCAATCTCAGCGGCTCTGGAAGCAAGATCCGCGACTTTGACATCTCTGA
GGGAGATCACATCCGACTCGACACAGACGGGAGTTACGCCTTTGACACCGATAGTCTGAAACTGACGCGCTCTGGCTTTC
GGATAAACACAATCGACTCAGACTCGAATGTCGAGACGCTTCGGGTCGTGCTGAATGATGACGCGAGACATGACCTCAGC
CTCGACGCGCTGTGGGACGTCCTGACATTTGGCTGA

Upstream 100 bases:

>100_bases
CGAGCTTGAGGCAATGGAAGCTTGATCCGGAGTTAGGCTTCTCGGTAATTTGAAATGGCTCCCATTTGGGAGCCATTTTT
ACATCAGGAACGATTTTCTC

Downstream 100 bases:

>100_bases
ATGACCTCTCCCCGTCCGCAAAACACGGCTTCACCATCGCTCCTGCCGCTTTCGCGTTCGGACCATGATCTGGTCCGAGA
TATTGCCGTCGCGCCCGAAC

Product: hemolysin-type calcium-binding region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAILTSSDSIDAILFPSTFISGGYIFPTPVYRYDVTDSYISYTLDQTRGSTGYYNINPTVRIFGDNLSVDSSGRASGTIT
AMEFRSSNRGEIARIEQISINASDFTDIIFARISGDNTSSTQFETLLAEALDVLEFGNRNQDISDRGMLQYLSFIDLQGG
NDEFHLARPKTDGTRTIDGGAGQDTLHLDDFGVPDSFVVNLKTGQIITDSTSVNITGFEIIDGNPFVDRYIGSNSGDHIR
AAGRADQINGFGGRDTLSGGWGDDRITGGRGKDRLHGDEGNDFLRGDAGADLLVGGAGRDRLVGRAGQDTLIADDGRDRL
IGGAGSDLFVFNLSGSGSKIRDFDISEGDHIRLDTDGSYAFDTDSLKLTRSGFRINTIDSDSNVETLRVVLNDDARHDLS
LDALWDVLTFG

Sequences:

>Translated_411_residues
MAILTSSDSIDAILFPSTFISGGYIFPTPVYRYDVTDSYISYTLDQTRGSTGYYNINPTVRIFGDNLSVDSSGRASGTIT
AMEFRSSNRGEIARIEQISINASDFTDIIFARISGDNTSSTQFETLLAEALDVLEFGNRNQDISDRGMLQYLSFIDLQGG
NDEFHLARPKTDGTRTIDGGAGQDTLHLDDFGVPDSFVVNLKTGQIITDSTSVNITGFEIIDGNPFVDRYIGSNSGDHIR
AAGRADQINGFGGRDTLSGGWGDDRITGGRGKDRLHGDEGNDFLRGDAGADLLVGGAGRDRLVGRAGQDTLIADDGRDRL
IGGAGSDLFVFNLSGSGSKIRDFDISEGDHIRLDTDGSYAFDTDSLKLTRSGFRINTIDSDSNVETLRVVLNDDARHDLS
LDALWDVLTFG
>Mature_410_residues
AILTSSDSIDAILFPSTFISGGYIFPTPVYRYDVTDSYISYTLDQTRGSTGYYNINPTVRIFGDNLSVDSSGRASGTITA
MEFRSSNRGEIARIEQISINASDFTDIIFARISGDNTSSTQFETLLAEALDVLEFGNRNQDISDRGMLQYLSFIDLQGGN
DEFHLARPKTDGTRTIDGGAGQDTLHLDDFGVPDSFVVNLKTGQIITDSTSVNITGFEIIDGNPFVDRYIGSNSGDHIRA
AGRADQINGFGGRDTLSGGWGDDRITGGRGKDRLHGDEGNDFLRGDAGADLLVGGAGRDRLVGRAGQDTLIADDGRDRLI
GGAGSDLFVFNLSGSGSKIRDFDISEGDHIRLDTDGSYAFDTDSLKLTRSGFRINTIDSDSNVETLRVVLNDDARHDLSL
DALWDVLTFG

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 44409; Mature: 44278

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAILTSSDSIDAILFPSTFISGGYIFPTPVYRYDVTDSYISYTLDQTRGSTGYYNINPTV
CEEEECCCCCCEEEECHHHHCCCEECCCCEEEEECCCCCEEEEEECCCCCCCEEECCCEE
RIFGDNLSVDSSGRASGTITAMEFRSSNRGEIARIEQISINASDFTDIIFARISGDNTSS
EEEECCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCC
TQFETLLAEALDVLEFGNRNQDISDRGMLQYLSFIDLQGGNDEFHLARPKTDGTRTIDGG
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEEECCCCCCEEEECCCCCCCEEECCC
AGQDTLHLDDFGVPDSFVVNLKTGQIITDSTSVNITGFEIIDGNPFVDRYIGSNSGDHIR
CCCCEEEECCCCCCCEEEEEEECCEEEECCCEEEEEEEEEECCCCHHHHHCCCCCCCEEE
AAGRADQINGFGGRDTLSGGWGDDRITGGRGKDRLHGDEGNDFLRGDAGADLLVGGAGRD
ECCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEECCCCCEEEEECCCCC
RLVGRAGQDTLIADDGRDRLIGGAGSDLFVFNLSGSGSKIRDFDISEGDHIRLDTDGSYA
HHCCCCCCCCEEECCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCCCEEEEECCCCEE
FDTDSLKLTRSGFRINTIDSDSNVETLRVVLNDDARHDLSLDALWDVLTFG
EECCCEEEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
AILTSSDSIDAILFPSTFISGGYIFPTPVYRYDVTDSYISYTLDQTRGSTGYYNINPTV
EEEECCCCCCEEEECHHHHCCCEECCCCEEEEECCCCCEEEEEECCCCCCCEEECCCEE
RIFGDNLSVDSSGRASGTITAMEFRSSNRGEIARIEQISINASDFTDIIFARISGDNTSS
EEEECCCCCCCCCCCCEEEEEEEECCCCCCCEEEEEEEEECCCCCCEEEEEEECCCCCCC
TQFETLLAEALDVLEFGNRNQDISDRGMLQYLSFIDLQGGNDEFHLARPKTDGTRTIDGG
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHEEECCCCCCEEEECCCCCCCEEECCC
AGQDTLHLDDFGVPDSFVVNLKTGQIITDSTSVNITGFEIIDGNPFVDRYIGSNSGDHIR
CCCCEEEECCCCCCCEEEEEEECCEEEECCCEEEEEEEEEECCCCHHHHHCCCCCCCEEE
AAGRADQINGFGGRDTLSGGWGDDRITGGRGKDRLHGDEGNDFLRGDAGADLLVGGAGRD
ECCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEEECCCCCEEEEECCCCC
RLVGRAGQDTLIADDGRDRLIGGAGSDLFVFNLSGSGSKIRDFDISEGDHIRLDTDGSYA
HHCCCCCCCCEEECCCCCEEEECCCCEEEEEEECCCCCEEEEEECCCCCEEEEECCCCEE
FDTDSLKLTRSGFRINTIDSDSNVETLRVVLNDDARHDLSLDALWDVLTFG
EECCCEEEEECCCEEEEECCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]