| Definition | Ruegeria sp. TM1040, complete genome. |
|---|---|
| Accession | NC_008044 |
| Length | 3,200,938 |
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The map label for this gene is lysC [C]
Identifier: 99080395
GI number: 99080395
Start: 590711
End: 592147
Strand: Direct
Name: lysC [C]
Synonym: TM1040_0554
Alternate gene names: 99080395
Gene position: 590711-592147 (Clockwise)
Preceding gene: 99080394
Following gene: 99080403
Centisome position: 18.45
GC content: 59.01
Gene sequence:
>1437_bases ATGACACATACTGTTGAAAAAATTGGCGGGACATCCATGTCCCGCGTGAACGAGCTGGTCGGCACGCTCTTTACTGGGGG TCGCAAACCGGATGATCTCTATGGCCGTGTGTTTGTGGTCTCGGCGTTTGGTGGCATCACCAACCTGCTGCTTGAACACA AGAAAACAGGTGAGCCGGGCGTCTATGCCCGGTTCGCAGACGCCGAATCCGATCATGGCTGGCACGAGGCGCTGAGTCGC GTGGGCGACGAGATGCGCAAGGCTCATGAGGCGGTTCTGGAGAACGCGGGCGATGTGGCGCAGGCTGACGCCTTTGTCTC CGAGCGCATCGAAGGCGCGCGCAACTGTCTGATCGATCTTCAGCGCCTGTGCAGCTACGGGCACTTCCGCCTGGCAGAGC ACATGCTGCAAATCCGGGAGCTGCTGTCGGGGCTGGGCGAGGCGCATTCCGCCTATGTGACCGCACTTTTGTTGCAGCGC GCGGGCGTGAATGCACGTTTTGTGGACCTCTCGGGCTGGCGCGACGAAGGTGACGTGACGCTAGAGGAACGCATCTCGAG CGCTCTAAATGACGTCGATCCGGCAACGGAAATGCCGATTGTCACAGGCTATGCACAATGCGCCGAAGGCCTGATGCGCG AGTTTGATCGCGGTTATTCCGAGGTGACGTTTTCCTGTCTGGCAGCCCTGACCGGGGCCAGCGAGGCGATCATCCACAAG GAATTCCACCTCTCCTCGGCCGATCCGAAGCTGGTGGGTGAGGGCGTGGCGCAGAAGCTCGGCCACACCAACTATGATGT TGCAGATCAGATGTCGAACATGGGCATGGAGGCCATCCACCCCAAGGCGGCCAAGACTCTACGTCAGGCCGATGTGCCGC TGCGGGTTACCAATGCGTTTGAACCCGAAGATCCAGGCACGCTCATCGACGACAAGCCGGCCGATCAGCCTGCAGTGGAG ATGATTACGGGTCTCGACATCATCGCGCTTGAGCTCTTTGAGCAGGATATGGTCGGGGTGAAAGGCTATGATGCTGCCAT TCTTGAGGTGCTGACACGCCACGATGTGCGCATCGTCTCCAAGACCTCGAATGCGAATACCATCACGCATTATCTCGACA CTTCCTTGACGGTTTTGAAACGGGTGGAGAAAGATCTCGCAAAGATCTACCCCAACGCGGATATTTCCGCGCGGCTCCTG TCGATGGCGTCCGCAATTGGGCGCGATCTCAAGGGGTTGTCGGTTCTCACCCGTGGCTTGCAGGCCATTGCGGACGTGGG TCTCGCAAGTCTGGGCGCCTCTCAGGGGCCGCGCAACGTGGACGTACAGTTCATCGTGGAACGCGAAGATCTGAAACCTG TGATCAGTGCTTTGCACAAGGTTCTGGTCGAGGGCAGACCCGCAAAACAGGAGAAGCCGATCAAAGCGGCAGCCTGA
Upstream 100 bases:
>100_bases TTCAACCCGCCAGTGACCGGCACAGAGGTCCATCGCGAAGATGGCTCCTATGCTCCGGCGGAGGAGCTGGCCTGATTCAG GCTCGAGAAACAGGTGACGT
Downstream 100 bases:
>100_bases CCTAAACACAGCCGTCGTCTGACAGGGATGATGCATCACCAAAGAAGGGGCGCCTGCGGGTGCCCCTTTGTGCGTTGCGG CTACATGTGGCTGGGAAGGT
Product: aspartate kinase
Products: NA
Alternate protein names: Aspartate kinase [H]
Number of amino acids: Translated: 478; Mature: 477
Protein sequence:
>478_residues MTHTVEKIGGTSMSRVNELVGTLFTGGRKPDDLYGRVFVVSAFGGITNLLLEHKKTGEPGVYARFADAESDHGWHEALSR VGDEMRKAHEAVLENAGDVAQADAFVSERIEGARNCLIDLQRLCSYGHFRLAEHMLQIRELLSGLGEAHSAYVTALLLQR AGVNARFVDLSGWRDEGDVTLEERISSALNDVDPATEMPIVTGYAQCAEGLMREFDRGYSEVTFSCLAALTGASEAIIHK EFHLSSADPKLVGEGVAQKLGHTNYDVADQMSNMGMEAIHPKAAKTLRQADVPLRVTNAFEPEDPGTLIDDKPADQPAVE MITGLDIIALELFEQDMVGVKGYDAAILEVLTRHDVRIVSKTSNANTITHYLDTSLTVLKRVEKDLAKIYPNADISARLL SMASAIGRDLKGLSVLTRGLQAIADVGLASLGASQGPRNVDVQFIVEREDLKPVISALHKVLVEGRPAKQEKPIKAAA
Sequences:
>Translated_478_residues MTHTVEKIGGTSMSRVNELVGTLFTGGRKPDDLYGRVFVVSAFGGITNLLLEHKKTGEPGVYARFADAESDHGWHEALSR VGDEMRKAHEAVLENAGDVAQADAFVSERIEGARNCLIDLQRLCSYGHFRLAEHMLQIRELLSGLGEAHSAYVTALLLQR AGVNARFVDLSGWRDEGDVTLEERISSALNDVDPATEMPIVTGYAQCAEGLMREFDRGYSEVTFSCLAALTGASEAIIHK EFHLSSADPKLVGEGVAQKLGHTNYDVADQMSNMGMEAIHPKAAKTLRQADVPLRVTNAFEPEDPGTLIDDKPADQPAVE MITGLDIIALELFEQDMVGVKGYDAAILEVLTRHDVRIVSKTSNANTITHYLDTSLTVLKRVEKDLAKIYPNADISARLL SMASAIGRDLKGLSVLTRGLQAIADVGLASLGASQGPRNVDVQFIVEREDLKPVISALHKVLVEGRPAKQEKPIKAAA >Mature_477_residues THTVEKIGGTSMSRVNELVGTLFTGGRKPDDLYGRVFVVSAFGGITNLLLEHKKTGEPGVYARFADAESDHGWHEALSRV GDEMRKAHEAVLENAGDVAQADAFVSERIEGARNCLIDLQRLCSYGHFRLAEHMLQIRELLSGLGEAHSAYVTALLLQRA GVNARFVDLSGWRDEGDVTLEERISSALNDVDPATEMPIVTGYAQCAEGLMREFDRGYSEVTFSCLAALTGASEAIIHKE FHLSSADPKLVGEGVAQKLGHTNYDVADQMSNMGMEAIHPKAAKTLRQADVPLRVTNAFEPEDPGTLIDDKPADQPAVEM ITGLDIIALELFEQDMVGVKGYDAAILEVLTRHDVRIVSKTSNANTITHYLDTSLTVLKRVEKDLAKIYPNADISARLLS MASAIGRDLKGLSVLTRGLQAIADVGLASLGASQGPRNVDVQFIVEREDLKPVISALHKVLVEGRPAKQEKPIKAAA
Specific function: Lysine biosynthesis; first step. [C]
COG id: COG0527
COG function: function code E; Aspartokinases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ACT domains [H]
Homologues:
Organism=Saccharomyces cerevisiae, GI6320893, Length=506, Percent_Identity=21.9367588932806, Blast_Score=70, Evalue=5e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR001048 - InterPro: IPR005260 - InterPro: IPR001341 - InterPro: IPR018042 [H]
Pfam domain/function: PF00696 AA_kinase; PF01842 ACT [H]
EC number: =2.7.2.4 [H]
Molecular weight: Translated: 51833; Mature: 51701
Theoretical pI: Translated: 5.16; Mature: 5.16
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTHTVEKIGGTSMSRVNELVGTLFTGGRKPDDLYGRVFVVSAFGGITNLLLEHKKTGEPG CCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHEEHHHHHHHHHHHHHCCCCCCC VYARFADAESDHGWHEALSRVGDEMRKAHEAVLENAGDVAQADAFVSERIEGARNCLIDL CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH QRLCSYGHFRLAEHMLQIRELLSGLGEAHSAYVTALLLQRAGVNARFVDLSGWRDEGDVT HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC LEERISSALNDVDPATEMPIVTGYAQCAEGLMREFDRGYSEVTFSCLAALTGASEAIIHK HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHH EFHLSSADPKLVGEGVAQKLGHTNYDVADQMSNMGMEAIHPKAAKTLRQADVPLRVTNAF HHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHCHHHHHHHHHCCCCEEECCCC EPEDPGTLIDDKPADQPAVEMITGLDIIALELFEQDMVGVKGYDAAILEVLTRHDVRIVS CCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEE KTSNANTITHYLDTSLTVLKRVEKDLAKIYPNADISARLLSMASAIGRDLKGLSVLTRGL ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH QAIADVGLASLGASQGPRNVDVQFIVEREDLKPVISALHKVLVEGRPAKQEKPIKAAA HHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC >Mature Secondary Structure THTVEKIGGTSMSRVNELVGTLFTGGRKPDDLYGRVFVVSAFGGITNLLLEHKKTGEPG CCCHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHEEHHHHHHHHHHHHHCCCCCCC VYARFADAESDHGWHEALSRVGDEMRKAHEAVLENAGDVAQADAFVSERIEGARNCLIDL CEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH QRLCSYGHFRLAEHMLQIRELLSGLGEAHSAYVTALLLQRAGVNARFVDLSGWRDEGDVT HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC LEERISSALNDVDPATEMPIVTGYAQCAEGLMREFDRGYSEVTFSCLAALTGASEAIIHK HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHH EFHLSSADPKLVGEGVAQKLGHTNYDVADQMSNMGMEAIHPKAAKTLRQADVPLRVTNAF HHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHCHHHHHHHHHCCCCEEECCCC EPEDPGTLIDDKPADQPAVEMITGLDIIALELFEQDMVGVKGYDAAILEVLTRHDVRIVS CCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCEEEEE KTSNANTITHYLDTSLTVLKRVEKDLAKIYPNADISARLLSMASAIGRDLKGLSVLTRGL ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHH QAIADVGLASLGASQGPRNVDVQFIVEREDLKPVISALHKVLVEGRPAKQEKPIKAAA HHHHHHHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]