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The map label for this gene is ectC [H]

Identifier: 99080394

GI number: 99080394

Start: 590293

End: 590685

Strand: Direct

Name: ectC [H]

Synonym: TM1040_0553

Alternate gene names: 99080394

Gene position: 590293-590685 (Clockwise)

Preceding gene: 99080393

Following gene: 99080395

Centisome position: 18.44

GC content: 54.45

Gene sequence:

>393_bases
ATGATCGTACGCGATTTCAACGAACTGAAAAACACTGACCGCTCCGTCTCTGATGCGCGCTGGACATCCACCCGTATGTT
GCTCGCTGATGATGGTATGGGCTTTTCCTTCCACATCACTGTGCTGGAAGCGGGTTCTGAACATCAGTTCCACTACAAAC
ACCACTTCGAGAGCGTTTATTGCATGAAAGGTAAGGGCTCGATCACGGATATCGCCACCGGCGAGACCCATGAGATCAAG
CCTGGTGTCATGTATGCGCTGAACCTGCACGACAAACACATCCTCCGGGCAGAAGAAGAGCTGCATATGGCGTGCTGTTT
CAACCCGCCAGTGACCGGCACAGAGGTCCATCGCGAAGATGGCTCCTATGCTCCGGCGGAGGAGCTGGCCTGA

Upstream 100 bases:

>100_bases
GCTTTGCGAAGGCTTCGCCATCCTGAGCACTGCGGCCCGCGAAGTGGCTGCAAAAACCAAAATTGCCGCGCAATAATCTG
AAGACCGGAGACCAAGACTA

Downstream 100 bases:

>100_bases
TTCAGGCTCGAGAAACAGGTGACGTATGACACATACTGTTGAAAAAATTGGCGGGACATCCATGTCCCGCGTGAACGAGC
TGGTCGGCACGCTCTTTACT

Product: L-ectoine synthase

Products: NA

Alternate protein names: N-acetyldiaminobutyrate dehydratase [H]

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MIVRDFNELKNTDRSVSDARWTSTRMLLADDGMGFSFHITVLEAGSEHQFHYKHHFESVYCMKGKGSITDIATGETHEIK
PGVMYALNLHDKHILRAEEELHMACCFNPPVTGTEVHREDGSYAPAEELA

Sequences:

>Translated_130_residues
MIVRDFNELKNTDRSVSDARWTSTRMLLADDGMGFSFHITVLEAGSEHQFHYKHHFESVYCMKGKGSITDIATGETHEIK
PGVMYALNLHDKHILRAEEELHMACCFNPPVTGTEVHREDGSYAPAEELA
>Mature_130_residues
MIVRDFNELKNTDRSVSDARWTSTRMLLADDGMGFSFHITVLEAGSEHQFHYKHHFESVYCMKGKGSITDIATGETHEIK
PGVMYALNLHDKHILRAEEELHMACCFNPPVTGTEVHREDGSYAPAEELA

Specific function: Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ectoine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR010462
- InterPro:   IPR014710
- ProDom:   PD080544 [H]

Pfam domain/function: PF06339 Ectoine_synth [H]

EC number: =4.2.1.108 [H]

Molecular weight: Translated: 14709; Mature: 14709

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVRDFNELKNTDRSVSDARWTSTRMLLADDGMGFSFHITVLEAGSEHQFHYKHHFESVY
CCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCEEEEECCCEEE
CMKGKGSITDIATGETHEIKPGVMYALNLHDKHILRAEEELHMACCFNPPVTGTEVHRED
EECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCEEEEEECCCCCCCCEEECCC
GSYAPAEELA
CCCCCHHHCC
>Mature Secondary Structure
MIVRDFNELKNTDRSVSDARWTSTRMLLADDGMGFSFHITVLEAGSEHQFHYKHHFESVY
CCCCCCHHHCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCCEEEEECCCEEE
CMKGKGSITDIATGETHEIKPGVMYALNLHDKHILRAEEELHMACCFNPPVTGTEVHRED
EECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEECCCCCEEEEEECCCCCCCCEEECCC
GSYAPAEELA
CCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA