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The map label for this gene is lldR [H]

Identifier: 99080206

GI number: 99080206

Start: 374933

End: 375625

Strand: Reverse

Name: lldR [H]

Synonym: TM1040_0365

Alternate gene names: 99080206

Gene position: 375625-374933 (Counterclockwise)

Preceding gene: 99080207

Following gene: 99080195

Centisome position: 11.73

GC content: 65.66

Gene sequence:

>693_bases
GTGGCTCTGAGCCACCCCAACCCTCCGGAGCAAGCACTGCGCGAAGCCATCCTCAATGCGGGCGCGTCACCCGATGGCCG
CCTGCCACCCGAACGGATCCTCGCGGCGCAGCTCTCGATCTCTCGCACCCAGTTGCGTGGGATCCTGGACGCGATGGCGC
GAGATGGGCTGATCTTTCGCCGTCACGGACAGGGTACGTTTTTGCAGCCACCTCCCGTGCAGGCTGCGGAGCGCCTGAGC
ACGCTTGCCAAACGCGTCACGCCGCGCGATCTGATGGAGGTCCGTCTCGATCTCGAACCGGCGCTCGCTGCCCATGCCGC
CCGGCGCGGCAGCGCAAAGGATAAGGCACGCCTGCTTCAACTTATGGAACACAGCCTCGCGGCGGACGATATTGAGCGCT
ACGAACACGCGGATGATCTCTTTCACTACAAGATTGCCGAGATGGCTGGAAACCCGCTGTTCCTGTCACTCTTTGAAGAA
ATTCGCACCCTGCGACGTGCAGGCGACTGGCAACGCACGCGGCGCGCAGCGCTCACGGGCGACGACATCGCGCGCCTCCC
GGCGCTGCACCGCGACATAGCGCAGTCCATCTGCGCCGGATCCGCCGAAGACGCCCGCGCCGCCATGCGCCAGCATTTGC
AGCAAGTCTCCGGAGCACTCCGCCGCGGCGATGCGGCGTCCGGTGAGAGTTAG

Upstream 100 bases:

>100_bases
TGGCCCACTCGATCCCCCGCCGTGCACTCAAACTCTCGTTTGGGGTCTTTTTGATGGCGACCTCCCTGCGCATGTTTGCC
GATCTCGCGGAGCAAATGGG

Downstream 100 bases:

>100_bases
CACGGCCCGCACCGCCAGCCCAACGGGCGCGCCAGCGCCTCAGCCTGCGCGCCGCAGGCGCTCCGCAGGACGACCCGGCA
TCAGGTGCCGAGGTCCTTTA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MALSHPNPPEQALREAILNAGASPDGRLPPERILAAQLSISRTQLRGILDAMARDGLIFRRHGQGTFLQPPPVQAAERLS
TLAKRVTPRDLMEVRLDLEPALAAHAARRGSAKDKARLLQLMEHSLAADDIERYEHADDLFHYKIAEMAGNPLFLSLFEE
IRTLRRAGDWQRTRRAALTGDDIARLPALHRDIAQSICAGSAEDARAAMRQHLQQVSGALRRGDAASGES

Sequences:

>Translated_230_residues
MALSHPNPPEQALREAILNAGASPDGRLPPERILAAQLSISRTQLRGILDAMARDGLIFRRHGQGTFLQPPPVQAAERLS
TLAKRVTPRDLMEVRLDLEPALAAHAARRGSAKDKARLLQLMEHSLAADDIERYEHADDLFHYKIAEMAGNPLFLSLFEE
IRTLRRAGDWQRTRRAALTGDDIARLPALHRDIAQSICAGSAEDARAAMRQHLQQVSGALRRGDAASGES
>Mature_229_residues
ALSHPNPPEQALREAILNAGASPDGRLPPERILAAQLSISRTQLRGILDAMARDGLIFRRHGQGTFLQPPPVQAAERLST
LAKRVTPRDLMEVRLDLEPALAAHAARRGSAKDKARLLQLMEHSLAADDIERYEHADDLFHYKIAEMAGNPLFLSLFEEI
RTLRRAGDWQRTRRAALTGDDIARLPALHRDIAQSICAGSAEDARAAMRQHLQQVSGALRRGDAASGES

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=206, Percent_Identity=31.5533980582524, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1786303, Length=218, Percent_Identity=32.1100917431193, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790780, Length=216, Percent_Identity=28.7037037037037, Blast_Score=69, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25307; Mature: 25176

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSHPNPPEQALREAILNAGASPDGRLPPERILAAQLSISRTQLRGILDAMARDGLIFR
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
RHGQGTFLQPPPVQAAERLSTLAKRVTPRDLMEVRLDLEPALAAHAARRGSAKDKARLLQ
ECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
LMEHSLAADDIERYEHADDLFHYKIAEMAGNPLFLSLFEEIRTLRRAGDWQRTRRAALTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCC
DDIARLPALHRDIAQSICAGSAEDARAAMRQHLQQVSGALRRGDAASGES
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALSHPNPPEQALREAILNAGASPDGRLPPERILAAQLSISRTQLRGILDAMARDGLIFR
CCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEE
RHGQGTFLQPPPVQAAERLSTLAKRVTPRDLMEVRLDLEPALAAHAARRGSAKDKARLLQ
ECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHH
LMEHSLAADDIERYEHADDLFHYKIAEMAGNPLFLSLFEEIRTLRRAGDWQRTRRAALTG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCC
DDIARLPALHRDIAQSICAGSAEDARAAMRQHLQQVSGALRRGDAASGES
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]