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The map label for this gene is degQ [C]

Identifier: 99080128

GI number: 99080128

Start: 292758

End: 294155

Strand: Direct

Name: degQ [C]

Synonym: TM1040_0287

Alternate gene names: 99080128

Gene position: 292758-294155 (Clockwise)

Preceding gene: 99080127

Following gene: 99080129

Centisome position: 9.15

GC content: 62.66

Gene sequence:

>1398_bases
ATGATCCGCAGTCTCGCCCTTCCCCTGACGATTGCCCTCGCAACTGCTCTGCCGCTTGCGTCACCAGCAGAGACCAAGAT
CCCGCAGAGCCAGACCGAGATCTCGCTGGGCTTTGCCCCCTTGGTCAAAGAGGCCGCGCCCGCTGTGGTGAATATCTATG
CCAAGATCATCCGTCAGGACCGTGCGCGCAGCCCCTTTGCCGATGATCCTTTCTTTGATGATTTCTTTCGCCAGTTTGCC
CAGCCGCGCCCAAGGGTGCAGAACTCGCTCGGCTCTGGTGTAATCCTCTCCGAAGATGGCATCGTGGTCTCCAACTATCA
CGTCGTGGGCGAGGCGTCGGATATTCGCGTGGTGACCAACGACCGCCGTGAATATCAGGCCGAGGTGATCCTTGCGGATC
AGGCGTCCGATCTGGCGATCCTGCAACTGCAAGATGCCGAAGGGCTGCCGCATCTGGGATTGCGCAACAGTGATGAGGTC
GAGGTGGGCGAGCTGACCCTGGCCATCGGCAACCCGTTCGGGGTCGGTCAGACGGTGTCCTCCGGCATTATTTCCGGGCT
TGCGCGCACCGGTACCGGCGGCGGGCAGGGCTTTGGCTATTACATCCAGACCGATGCGCCGATCAATCCTGGCAACTCTG
GTGGGGCGCTGATTGATGTGAATGGCGATCTCATCGGGATCAACACGCGGATCCTCAGCCGTTCGGGTGGCTCCAACGGG
ATTGGCTTTGCCATTCCGGCCAATCTGGTGCGTGAATTTGTGCGACAGGCGCGGGCCGGTGCAGAGGAGTTTCAACGCCC
CTGGGCGGGGATGACTGGCCAGCCGGTGGATTCCGATCTGGCAGAAGCGCTGGGCCTTGGTCAGGTGGATGGGATGTTGA
TTTCAGAGCTCCACCCCCAGAGCCCCTTTGTCGAGGCGGGATTTGAGGTTGGCGATGTGGTGCTGGCCGTGGATGGCGAG
CCGGTGAACTCGCCCTCGGAGATGGCCTTTCGCTTGTCGGTGGCGGAACTGGGCGGCACCAGCGCGGTGACGCGGGTGCG
TCAGGGCAAGACGGACACTGTTGAGGTCGCCTTGATCGAAGCGCCTGACACCCCCGCCGCCGATCCGATCACGCTGAGCG
AGCGCACCCCGATGCCGGGTCTGGTGGTGGGACGGGTGAACCCGCAGGTCATCACCAAGATGCAGCTACCGCTATCGACC
GAGGGTGTTGTGGTGATGGACCCCGGCCCCTATGCCGGACGCGGCGGCGTGCGCGCGGGGGATTTGATTTTTGCGATCAA
CGGCGAGGCGGTTGAGGCCCCCGAAGATGTAGCAAATCTCCTGATGAGCAGTGACCGCTGGATGCGGATGGACCTGATGC
GTCAGGGCCAGCGCGTGTCTCTGCGGTTCCGGCTCTGA

Upstream 100 bases:

>100_bases
GCGCCCCTCAGCCGCCTTTGTGCTGTTGCGCAGCAGCGGCTTGCAATCCCCTGCGCGCCTTCGCATATCATCAGGACCAA
AATCACGTCCCGGAGGCCCC

Downstream 100 bases:

>100_bases
CATGGCGGATCTCTTTGACAGCGAGGAGGCGGGCGCTCGGGCGGCGCAGAACGGGGCCAGTGATGCCCCGCGCCCGCTCG
CGGACCGGTTGCGGCCCCGA

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MIRSLALPLTIALATALPLASPAETKIPQSQTEISLGFAPLVKEAAPAVVNIYAKIIRQDRARSPFADDPFFDDFFRQFA
QPRPRVQNSLGSGVILSEDGIVVSNYHVVGEASDIRVVTNDRREYQAEVILADQASDLAILQLQDAEGLPHLGLRNSDEV
EVGELTLAIGNPFGVGQTVSSGIISGLARTGTGGGQGFGYYIQTDAPINPGNSGGALIDVNGDLIGINTRILSRSGGSNG
IGFAIPANLVREFVRQARAGAEEFQRPWAGMTGQPVDSDLAEALGLGQVDGMLISELHPQSPFVEAGFEVGDVVLAVDGE
PVNSPSEMAFRLSVAELGGTSAVTRVRQGKTDTVEVALIEAPDTPAADPITLSERTPMPGLVVGRVNPQVITKMQLPLST
EGVVVMDPGPYAGRGGVRAGDLIFAINGEAVEAPEDVANLLMSSDRWMRMDLMRQGQRVSLRFRL

Sequences:

>Translated_465_residues
MIRSLALPLTIALATALPLASPAETKIPQSQTEISLGFAPLVKEAAPAVVNIYAKIIRQDRARSPFADDPFFDDFFRQFA
QPRPRVQNSLGSGVILSEDGIVVSNYHVVGEASDIRVVTNDRREYQAEVILADQASDLAILQLQDAEGLPHLGLRNSDEV
EVGELTLAIGNPFGVGQTVSSGIISGLARTGTGGGQGFGYYIQTDAPINPGNSGGALIDVNGDLIGINTRILSRSGGSNG
IGFAIPANLVREFVRQARAGAEEFQRPWAGMTGQPVDSDLAEALGLGQVDGMLISELHPQSPFVEAGFEVGDVVLAVDGE
PVNSPSEMAFRLSVAELGGTSAVTRVRQGKTDTVEVALIEAPDTPAADPITLSERTPMPGLVVGRVNPQVITKMQLPLST
EGVVVMDPGPYAGRGGVRAGDLIFAINGEAVEAPEDVANLLMSSDRWMRMDLMRQGQRVSLRFRL
>Mature_465_residues
MIRSLALPLTIALATALPLASPAETKIPQSQTEISLGFAPLVKEAAPAVVNIYAKIIRQDRARSPFADDPFFDDFFRQFA
QPRPRVQNSLGSGVILSEDGIVVSNYHVVGEASDIRVVTNDRREYQAEVILADQASDLAILQLQDAEGLPHLGLRNSDEV
EVGELTLAIGNPFGVGQTVSSGIISGLARTGTGGGQGFGYYIQTDAPINPGNSGGALIDVNGDLIGINTRILSRSGGSNG
IGFAIPANLVREFVRQARAGAEEFQRPWAGMTGQPVDSDLAEALGLGQVDGMLISELHPQSPFVEAGFEVGDVVLAVDGE
PVNSPSEMAFRLSVAELGGTSAVTRVRQGKTDTVEVALIEAPDTPAADPITLSERTPMPGLVVGRVNPQVITKMQLPLST
EGVVVMDPGPYAGRGGVRAGDLIFAINGEAVEAPEDVANLLMSSDRWMRMDLMRQGQRVSLRFRL

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=309, Percent_Identity=32.0388349514563, Blast_Score=142, Evalue=9e-34,
Organism=Homo sapiens, GI22129776, Length=330, Percent_Identity=31.2121212121212, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI24308541, Length=255, Percent_Identity=31.3725490196078, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI7019477, Length=293, Percent_Identity=34.4709897610922, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1789629, Length=439, Percent_Identity=34.624145785877, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1786356, Length=394, Percent_Identity=33.756345177665, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1789630, Length=375, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=5e-43,
Organism=Drosophila melanogaster, GI24646839, Length=287, Percent_Identity=29.616724738676, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 49257; Mature: 49257

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRSLALPLTIALATALPLASPAETKIPQSQTEISLGFAPLVKEAAPAVVNIYAKIIRQD
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECHHHHHHHHCHHHHHHHHHHHHHH
RARSPFADDPFFDDFFRQFAQPRPRVQNSLGSGVILSEDGIVVSNYHVVGEASDIRVVTN
HCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCEEEECCCEEEEEEEEEECCCCEEEEEC
DRREYQAEVILADQASDLAILQLQDAEGLPHLGLRNSDEVEVGELTLAIGNPFGVGQTVS
CCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHH
SGIISGLARTGTGGGQGFGYYIQTDAPINPGNSGGALIDVNGDLIGINTRILSRSGGSNG
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCC
IGFAIPANLVREFVRQARAGAEEFQRPWAGMTGQPVDSDLAEALGLGQVDGMLISELHPQ
CEEECCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHCCCC
SPFVEAGFEVGDVVLAVDGEPVNSPSEMAFRLSVAELGGTSAVTRVRQGKTDTVEVALIE
CCHHHCCCCCCCEEEEECCCCCCCHHHEEEEEEHHHCCCHHHHHHHHCCCCCEEEEEEEE
APDTPAADPITLSERTPMPGLVVGRVNPQVITKMQLPLSTEGVVVMDPGPYAGRGGVRAG
CCCCCCCCCEEECCCCCCCCEEEECCCHHEEEEEECCCCCCCEEEECCCCCCCCCCCCCC
DLIFAINGEAVEAPEDVANLLMSSDRWMRMDLMRQGQRVSLRFRL
CEEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHHCCCEEEEEEEC
>Mature Secondary Structure
MIRSLALPLTIALATALPLASPAETKIPQSQTEISLGFAPLVKEAAPAVVNIYAKIIRQD
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECHHHHHHHHCHHHHHHHHHHHHHH
RARSPFADDPFFDDFFRQFAQPRPRVQNSLGSGVILSEDGIVVSNYHVVGEASDIRVVTN
HCCCCCCCCCCHHHHHHHHCCCCCHHHHHCCCCEEEECCCEEEEEEEEEECCCCEEEEEC
DRREYQAEVILADQASDLAILQLQDAEGLPHLGLRNSDEVEVGELTLAIGNPFGVGQTVS
CCCEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHH
SGIISGLARTGTGGGQGFGYYIQTDAPINPGNSGGALIDVNGDLIGINTRILSRSGGSNG
HHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCEEEEEEEEEECCCCCCC
IGFAIPANLVREFVRQARAGAEEFQRPWAGMTGQPVDSDLAEALGLGQVDGMLISELHPQ
CEEECCHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHCCCC
SPFVEAGFEVGDVVLAVDGEPVNSPSEMAFRLSVAELGGTSAVTRVRQGKTDTVEVALIE
CCHHHCCCCCCCEEEEECCCCCCCHHHEEEEEEHHHCCCHHHHHHHHCCCCCEEEEEEEE
APDTPAADPITLSERTPMPGLVVGRVNPQVITKMQLPLSTEGVVVMDPGPYAGRGGVRAG
CCCCCCCCCEEECCCCCCCCEEEECCCHHEEEEEECCCCCCCEEEECCCCCCCCCCCCCC
DLIFAINGEAVEAPEDVANLLMSSDRWMRMDLMRQGQRVSLRFRL
CEEEEECCCCCCCHHHHHHHHHCCCCCEEHHHHHCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]