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The map label for this gene is aroG [H]

Identifier: 99080127

GI number: 99080127

Start: 291466

End: 292560

Strand: Direct

Name: aroG [H]

Synonym: TM1040_0286

Alternate gene names: 99080127

Gene position: 291466-292560 (Clockwise)

Preceding gene: 99080125

Following gene: 99080128

Centisome position: 9.11

GC content: 64.57

Gene sequence:

>1095_bases
ATGACCACCCTCTCTCAGACACCGACCCATGATCTGCGCATCACCGACATGCAGGAATTGATCTGCCCCGAAGCCCTCGC
GGTGAAACACCCGCTGACAGATGCCGCGCGCGAAACCGTGCTCTCGGCGCGCGCCAGCATCCAGAAGATCCTGCATGGCG
CCGACGACCGGCTGGTCGTCGTGGTCGGCCCCTGTTCGATCCACGACCCGGAGGCCGCGCTGGACTATGCGCGCCGTCTT
GCGCCGCTGCGCGCCGAGCTGGGCGATGCGCTTGAGATCGTGATGCGGGTCTACTTTGAAAAACCGCGCACCATCGCGGG
CTGGAAGGGGCTGATCAACGACCCCAACCTTGATGGGTCTTTCCGCATCAACAAGGGGTTGTCGGTCGCCCGCAAGCTCT
GCCTGGATCTGAGCGAAATGGGCCTGCCCGTGGGGACCGAATTCCTCGATGCCTCGGTGCCGCAATACATCAGTGATCTG
GTGAGCTGGGCCGCGATTGGCGCCCGCACCACCGAGAGCCAGATCCACCGCGAAATGGCTTCGGGCCTGAGCTGCCCGGT
GGGCTTCAAGAACGGCACCCGCGGCAATGTGCAGATCGCCATTGACGCGGTGCGCTCGGCGGCCACACCGCATCATTTCA
TGGCGCTGGCCCCCTCGGGTCTCGCGGCGATTGCGGCGACGGCCGGAAACCCGGATTGCCACATCATCCTGCGCGGCGGC
GGTGGTACCAACTTTGATGCCGAGAGCGTGGATTCAGCCTGCAAAAAGGCCGAAGCCGATGGCATCCGTCCGCAGGTGAT
GATCGACGCAAGCCACGCCAACTCTGCCAAGGATCCCGCCAAACAGCCCGAGGTGCTCTCGGATGTGGCCGGCCAGATGG
CACAGGGTGAGACCCGCATCACCGGCATCATGATCGAAAGCCACCTCGAACAGGGTCGTCAGGATCTGCCCAAGGACGGG
GACCTGTCGAAACTCACCTATGGTCAGTCGATCACCGACGGCTGCATCGGCTGGGAGCAAACCGAGGCCGAGCTGCGCAA
ACTGGCCCAGGCGGTCAAAACACGCCGCACGCAGGGCGCCCGCCTGGCGGGTTGA

Upstream 100 bases:

>100_bases
GACAGAAACAGCCGAATACCACACCAAACCGCCCCGGGACCGAGGGCGGTTTTTTGTTGCCCAGAGGTCCACGCGGGGCC
CCCGCCCAAGGAACCGCCCG

Downstream 100 bases:

>100_bases
GCTCGGATCAAAACGAAACGGGGCGGTGCACCGCCGCCCCCCTTCATCTTCTGACCAAAATATCCCGGGGTGAACTGACC
GCAGGTCAGGAGGGGCAGCG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MTTLSQTPTHDLRITDMQELICPEALAVKHPLTDAARETVLSARASIQKILHGADDRLVVVVGPCSIHDPEAALDYARRL
APLRAELGDALEIVMRVYFEKPRTIAGWKGLINDPNLDGSFRINKGLSVARKLCLDLSEMGLPVGTEFLDASVPQYISDL
VSWAAIGARTTESQIHREMASGLSCPVGFKNGTRGNVQIAIDAVRSAATPHHFMALAPSGLAAIAATAGNPDCHIILRGG
GGTNFDAESVDSACKKAEADGIRPQVMIDASHANSAKDPAKQPEVLSDVAGQMAQGETRITGIMIESHLEQGRQDLPKDG
DLSKLTYGQSITDGCIGWEQTEAELRKLAQAVKTRRTQGARLAG

Sequences:

>Translated_364_residues
MTTLSQTPTHDLRITDMQELICPEALAVKHPLTDAARETVLSARASIQKILHGADDRLVVVVGPCSIHDPEAALDYARRL
APLRAELGDALEIVMRVYFEKPRTIAGWKGLINDPNLDGSFRINKGLSVARKLCLDLSEMGLPVGTEFLDASVPQYISDL
VSWAAIGARTTESQIHREMASGLSCPVGFKNGTRGNVQIAIDAVRSAATPHHFMALAPSGLAAIAATAGNPDCHIILRGG
GGTNFDAESVDSACKKAEADGIRPQVMIDASHANSAKDPAKQPEVLSDVAGQMAQGETRITGIMIESHLEQGRQDLPKDG
DLSKLTYGQSITDGCIGWEQTEAELRKLAQAVKTRRTQGARLAG
>Mature_363_residues
TTLSQTPTHDLRITDMQELICPEALAVKHPLTDAARETVLSARASIQKILHGADDRLVVVVGPCSIHDPEAALDYARRLA
PLRAELGDALEIVMRVYFEKPRTIAGWKGLINDPNLDGSFRINKGLSVARKLCLDLSEMGLPVGTEFLDASVPQYISDLV
SWAAIGARTTESQIHREMASGLSCPVGFKNGTRGNVQIAIDAVRSAATPHHFMALAPSGLAAIAATAGNPDCHIILRGGG
GTNFDAESVDSACKKAEADGIRPQVMIDASHANSAKDPAKQPEVLSDVAGQMAQGETRITGIMIESHLEQGRQDLPKDGD
LSKLTYGQSITDGCIGWEQTEAELRKLAQAVKTRRTQGARLAG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786969, Length=346, Percent_Identity=59.2485549132948, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1788953, Length=354, Percent_Identity=52.2598870056497, Blast_Score=373, Evalue=1e-105,
Organism=Escherichia coli, GI1787996, Length=347, Percent_Identity=51.5850144092219, Blast_Score=367, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6320240, Length=352, Percent_Identity=51.1363636363636, Blast_Score=370, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6319726, Length=357, Percent_Identity=53.5014005602241, Blast_Score=370, Evalue=1e-103,

Paralogues:

None

Copy number: 600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 38884; Mature: 38752

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLSQTPTHDLRITDMQELICPEALAVKHPLTDAARETVLSARASIQKILHGADDRLVV
CCCCCCCCCCCEEECCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VVGPCSIHDPEAALDYARRLAPLRAELGDALEIVMRVYFEKPRTIAGWKGLINDPNLDGS
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCC
FRINKGLSVARKLCLDLSEMGLPVGTEFLDASVPQYISDLVSWAAIGARTTESQIHREMA
EEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SGLSCPVGFKNGTRGNVQIAIDAVRSAATPHHFMALAPSGLAAIAATAGNPDCHIILRGG
CCCCCCCCCCCCCCCCEEEEEEHHHHCCCCHHEEEECCCCCEEEEEECCCCCEEEEEECC
GGTNFDAESVDSACKKAEADGIRPQVMIDASHANSAKDPAKQPEVLSDVAGQMAQGETRI
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
TGIMIESHLEQGRQDLPKDGDLSKLTYGQSITDGCIGWEQTEAELRKLAQAVKTRRTQGA
HHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCC
RLAG
CCCC
>Mature Secondary Structure 
TTLSQTPTHDLRITDMQELICPEALAVKHPLTDAARETVLSARASIQKILHGADDRLVV
CCCCCCCCCCEEECCHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VVGPCSIHDPEAALDYARRLAPLRAELGDALEIVMRVYFEKPRTIAGWKGLINDPNLDGS
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCC
FRINKGLSVARKLCLDLSEMGLPVGTEFLDASVPQYISDLVSWAAIGARTTESQIHREMA
EEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
SGLSCPVGFKNGTRGNVQIAIDAVRSAATPHHFMALAPSGLAAIAATAGNPDCHIILRGG
CCCCCCCCCCCCCCCCEEEEEEHHHHCCCCHHEEEECCCCCEEEEEECCCCCEEEEEECC
GGTNFDAESVDSACKKAEADGIRPQVMIDASHANSAKDPAKQPEVLSDVAGQMAQGETRI
CCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCHHH
TGIMIESHLEQGRQDLPKDGDLSKLTYGQSITDGCIGWEQTEAELRKLAQAVKTRRTQGA
HHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCC
RLAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]