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The map label for this gene is rpoC [H]

Identifier: 99080076

GI number: 99080076

Start: 251905

End: 256137

Strand: Direct

Name: rpoC [H]

Synonym: TM1040_0235

Alternate gene names: 99080076

Gene position: 251905-256137 (Clockwise)

Preceding gene: 99080075

Following gene: 99080077

Centisome position: 7.87

GC content: 59.41

Gene sequence:

>4233_bases
ATGAACCAGGAAATCACCAACAACCCGTTCAACCCGCTGACTCCGCCCAAGGTCTTTGACGAAATCAAAGTCTCGCTGGC
CAGCCCCGAACGGATCCTGTCTTGGTCCTACGGCGAGATTAAAAAGCCGGAAACCATCAACTACCGTACGTTCAAGCCCG
AGCGTGACGGCCTGTTCTGCGCGCGTATCTTTGGCCCGATCAAAGACTACGAATGTCTCTGCGGCAAATATAAGCGCATG
AAGTATCGCGGCGTTGTCTGCGAGAAATGTGGTGTTGAAGTTACCCTTCAAAAAGTGCGCCGCGAGCGCATGGGCCACAT
CGAACTGGCGGCACCCGTTGCGCATATCTGGTTCCTGAAGTCGCTTCCTTCCCGGATCGGCCTCATGCTGGACATGACCC
TGCGTGATCTGGAACGTGTTCTGTACTTTGAAAACTACGTTGTCATCGAGCCGGGTCTGACTGACCTGCAATACGGCCAG
ATGATGACCGAAGAAGAGTACATGGACGCGCAAGACGCCTATGGCATGGACGCTTTCACCGCCAATATCGGTGCGGAAGC
GATCCGCGAAATGCTGGCGGCGATCGATCTTGAGGCAGAAGCCGAGCACCTGCGCGCCGAACTGGCCGAGGCCACCGGCG
AACTGAAGCCCAAGAAGATCATCAAACGTCTGAAAGTCGTTGAATCCTTCCTCGAGTCGGGCAACCGTCCTGAGTGGATG
ATCATGACCGTGATCCCGGTTATCCCGCCGGAACTGCGTCCGCTGGTTCCGCTGGATGGGGGCCGTTTTGCGACCTCCGA
CCTCAACGACCTCTATCGTCGTGTGATCAACCGGAACAATCGTCTGAAGCGACTCATCGAGCTGCGCGCGCCTGACATCA
TCGTCCGCAACGAAAAGCGGATGCTGCAGGAATCCGTTGATGCTCTGTTCGACAACGGCCGTCGTGGTCGCGTCATCACC
GGTGCCAACAAGCGTCCGCTGAAGTCGCTCTCCGACATGCTGAAGGGTAAGCAGGGTCGCTTCCGTCAGAACCTTCTCGG
TAAACGCGTCGACTTCTCCGGTCGTTCGGTTATTGTGACCGGCCCCGAGCTGAAGCTGCACCAGTGTGGCCTGCCCAAGA
AGATGGCGCTCGAACTCTTCAAGCCCTTCATCTACTCGCGTCTGGAGGCCAAAGGTCTGTCCTCCACCGTGAAGCAGGCG
AAGAAGCTCGTTGAAAAAGAACGTCCCGAAGTTTGGGATATCCTCGACGAGGTGATCCGCGAGCACCCGGTGATGCTGAA
CCGCGCACCGACGCTGCACCGTCTTGGTATTCAGGCGTTCGAACCCACGCTGATCGAAGGTAAAGCGATCCAGCTGCACC
CGCTGGTCTGTTCGGCGTTCAACGCGGACTTCGACGGTGACCAGATGGCCGTGCACGTCCCGCTGAGCCTTGAGGCCCAG
CTGGAAGCGCGCGTCCTGATGATGTCGACGAACAACGTTCTGTCGCCCGCAAACGGTGCGCCGATCATCGTTCCCTCGCA
GGATATGATCCTTGGTCTCTACTACCTCACGCTGGAGCGTGAAGGCATGAAGGGCGAAGGCAAGATCTTTGGCAACCTCG
ACGAGGTCCAGCACGCGCTGGACGCGGGCGAGGTGCATCTGCACTCCAAAGTGACCGTGCGGGTTCCGCAGATCGACGAA
GAGGGCAACGAAGTCTTCCAACGCTTCGAGACCACGCCGGGCCGTGCCCGTCTGGGCTCCTTGCTGCCGAAGAACGCCAA
GGCACCGTTTGAACTGGTGAACCGTCTGCTGCGCAAACGCGAAGTTCAGCAGGTCATCGACACCGTCTACCGTTACTGCG
GTCAGAAAGAGTCGGTGATCTTCTGTGACCAGATCATGACCATGGGCTTCCGCGAAGCGTTCAAGGCGGGCATCTCGTTC
GGCAAGGACGACATGGTGATCCCCGACAACAAGTGGACCATCGTCGACGACACCCGCGATCAGGTGAAAGACTTTGAACA
GCAGTACATGGACGGCCTGATCACTCAGGGCGAAAAGTACAACAAGGTTGTCGATGCCTGGTCGAAGTGTAACGACAAGC
TCACCGAAGCCATGATGTCCACCATCTCGGCGGTCAAAAAGGCTGAAGATGGCTCCGACATGGAACCGAACTCGGTCTAT
ATGATGGCGCACTCCGGTGCGCGTGGCTCCGTGACGCAGATGCGTCAGCTGGGCGGGATGCGCGGCCTGATGGCAAAGCC
GAACGGCGACATCATCGAGACCCCGGTTATCTCGAACTTTAAAGAAGGCCTCACCGTTCTGGAGTACTTCAACTCCACCC
ACGGTGCGCGTAAGGGTCTGTCGGACACCGCTCTGAAAACGGCGAACTCCGGTTACCTTACACGTCGTCTTGTGGACGTG
GCGCAGGACTGCATCGTGCGCGAGCACGACTGTGGCACCGAGCGTGCGATCACGGCTGAAACCGCGGTCAACGACGGTGA
AGTTGTGGCGTCTCTTGGTGAGCGTATCCTGGGTCGTGTGGCGGCAGATGACGTCAAGCGTCCAGGCACCGAAGAAGTCC
TGTTGGCTGCAGGTCAGCTCATTGACGAACGTATGGCCGACACCATCGAGGAAGCTGGCGTTCAGTCCATGCGCATCCGC
AGCCCGCTGACCTGTGAAAGCGAAGAGGGCGTCTGCGCCATGTGCTATGGCCGCGACCTTGCACGCGGCACCATGGTCAA
CTCCGGTGAGGCCGTCGGCATCATCGCGGCGCAGTCCATCGGTGAACCAGGTACACAGCTGACGATGCGGACCTTCCACA
TCGGCGGCGTGGCCCAGGGTGGTCAGCAGTCCTTCCTCGAGGCGTCCCAGGAGGGCAAGATCGTGTTCGAGAACACGAAC
ACGCTCACCAACGCCAACGGCGAAGTTCTGACCATCGGCCGGAACATGAAGCTGATCATTCAGGACGAGCACGGTGAAGA
GCGCTCCAGCCACAAGCTGGGCTACGGTACCAAGCTCTTTGTGAAAGAGGGCCAAGAGGTCAAACGCGGCGATAAACTGT
TCGAGTGGGACCCCTATACCCTGCCGATCATCGCCGAGAAGCCGGGTACCGCGAAGTACGTGGACCTCGTGTCCGGTCTG
GCCGTGCGCGAAGAAACCGACGATGCCACCGGCATGACCCAGAAGATCGTGATCGACTGGCGTGCGGCACCGAAGGGGTC
TGACCTGAAGCCGGAGATCATCCTTGTGGGTGACGATGGCGAACCAGTGCGCAACTCCCTTGGAAACCCGCTCACCTATC
CGATGTCCGTGGATGCGATCCTGTCCTGTGAAGATGGCCAGAAGATCGAAGCCGGTGACGTTGTTGCGCGTATCCCGCGT
GAAGGCGCGAAGACGAAGGACATTACCGGTGGTCTGCCGCGTGTGGCCGAACTCTTCGAGGCGCGTCGTCCGAAGGATCA
CGCGATCATCGCGGAAATCGACGGCTATGTGCGCTTTGGTCGTGACTACAAGAACAAGCGTCGTATCTCGATCGAGCCGG
CAGATGAGTCCATGGAGGCCGTGGAATACATGGTGCCCAAGGGCAAGCACATCCCGGTGGTCGAAGGCGACTTCGTTCAG
AAGGGCGACTACATCATGGACGGCAACCCGGCGCCGCATGACATCCTCTCCATCATGGGTGTCGAGGCTCTGGCGAACTA
CATGATCGACGAGGTGCAGGACGTCTATCGCCTGCAGGGTGTGAAGATCAACGACAAGCACATCGAGGTGATCGTTCGCC
AGATGCTGCAGAAGTGGGAGATCTCCGACTCTGGCGAGACCACGCTCCTCAAGGGCGAACACGTCGACAAGCAGGAGTTC
GACGCTGCAAACGAGAAGGCGCTGGCCCGTGGCAAGCGTCCTGCTCAGGGCGAGCCGATCCTTCTTGGTATCACCAAGGC
GTCGCTGCAGACCCGCTCCTTCATCTCCGCGGCCTCCTTCCAGGAGACCACACGGGTGCTCACCGAAGCCTCCGTACAGG
GCAAGAAGGACAAGCTGGTCGGCCTGAAGGAAAACGTCATCGTGGGTCGTCTGATCCCGGCGGGTACCGGTGGTGCCACC
CAGCAGGTGCGTCACATCGCGGCCTCGCGCGACAATGTGGTTCTTGAGGCCCGTCGTGAAGAAGCCGAAGCGGCGGCAGC
CCTTGCTGCGCCGATGGCGGATGATGCGGCGGATGCGGACTTCCTCGTGGAAACCCCGGAAAGCCGCGACTGA

Upstream 100 bases:

>100_bases
GCCTCGGCCTGAACATGGAACTCCTGGATGCGGAGGTTGAGGAGTGAGGGGGCTTCCCCTCACCCCACGTCCCCCCTTCC
GCAAGATTTGAGGTATCAAA

Downstream 100 bases:

>100_bases
GCCTGACCGGCCGTTTTGAAATGAAGAGCGCCCCGCGTCCACCGTGACGCGGGGCGCTTTTGTTTCGCGCGCGGGGCCTT
GCAGGTGTCGCGCCTAGGCT

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1410; Mature: 1410

Protein sequence:

>1410_residues
MNQEITNNPFNPLTPPKVFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRM
KYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERVLYFENYVVIEPGLTDLQYGQ
MMTEEEYMDAQDAYGMDAFTANIGAEAIREMLAAIDLEAEAEHLRAELAEATGELKPKKIIKRLKVVESFLESGNRPEWM
IMTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRVIT
GANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQA
KKLVEKERPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYLTLEREGMKGEGKIFGNLDEVQHALDAGEVHLHSKVTVRVPQIDE
EGNEVFQRFETTPGRARLGSLLPKNAKAPFELVNRLLRKREVQQVIDTVYRYCGQKESVIFCDQIMTMGFREAFKAGISF
GKDDMVIPDNKWTIVDDTRDQVKDFEQQYMDGLITQGEKYNKVVDAWSKCNDKLTEAMMSTISAVKKAEDGSDMEPNSVY
MMAHSGARGSVTQMRQLGGMRGLMAKPNGDIIETPVISNFKEGLTVLEYFNSTHGARKGLSDTALKTANSGYLTRRLVDV
AQDCIVREHDCGTERAITAETAVNDGEVVASLGERILGRVAADDVKRPGTEEVLLAAGQLIDERMADTIEEAGVQSMRIR
SPLTCESEEGVCAMCYGRDLARGTMVNSGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFLEASQEGKIVFENTN
TLTNANGEVLTIGRNMKLIIQDEHGEERSSHKLGYGTKLFVKEGQEVKRGDKLFEWDPYTLPIIAEKPGTAKYVDLVSGL
AVREETDDATGMTQKIVIDWRAAPKGSDLKPEIILVGDDGEPVRNSLGNPLTYPMSVDAILSCEDGQKIEAGDVVARIPR
EGAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGYVRFGRDYKNKRRISIEPADESMEAVEYMVPKGKHIPVVEGDFVQ
KGDYIMDGNPAPHDILSIMGVEALANYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWEISDSGETTLLKGEHVDKQEF
DAANEKALARGKRPAQGEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKKDKLVGLKENVIVGRLIPAGTGGAT
QQVRHIAASRDNVVLEARREEAEAAAALAAPMADDAADADFLVETPESRD

Sequences:

>Translated_1410_residues
MNQEITNNPFNPLTPPKVFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRM
KYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERVLYFENYVVIEPGLTDLQYGQ
MMTEEEYMDAQDAYGMDAFTANIGAEAIREMLAAIDLEAEAEHLRAELAEATGELKPKKIIKRLKVVESFLESGNRPEWM
IMTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRVIT
GANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQA
KKLVEKERPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYLTLEREGMKGEGKIFGNLDEVQHALDAGEVHLHSKVTVRVPQIDE
EGNEVFQRFETTPGRARLGSLLPKNAKAPFELVNRLLRKREVQQVIDTVYRYCGQKESVIFCDQIMTMGFREAFKAGISF
GKDDMVIPDNKWTIVDDTRDQVKDFEQQYMDGLITQGEKYNKVVDAWSKCNDKLTEAMMSTISAVKKAEDGSDMEPNSVY
MMAHSGARGSVTQMRQLGGMRGLMAKPNGDIIETPVISNFKEGLTVLEYFNSTHGARKGLSDTALKTANSGYLTRRLVDV
AQDCIVREHDCGTERAITAETAVNDGEVVASLGERILGRVAADDVKRPGTEEVLLAAGQLIDERMADTIEEAGVQSMRIR
SPLTCESEEGVCAMCYGRDLARGTMVNSGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFLEASQEGKIVFENTN
TLTNANGEVLTIGRNMKLIIQDEHGEERSSHKLGYGTKLFVKEGQEVKRGDKLFEWDPYTLPIIAEKPGTAKYVDLVSGL
AVREETDDATGMTQKIVIDWRAAPKGSDLKPEIILVGDDGEPVRNSLGNPLTYPMSVDAILSCEDGQKIEAGDVVARIPR
EGAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGYVRFGRDYKNKRRISIEPADESMEAVEYMVPKGKHIPVVEGDFVQ
KGDYIMDGNPAPHDILSIMGVEALANYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWEISDSGETTLLKGEHVDKQEF
DAANEKALARGKRPAQGEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKKDKLVGLKENVIVGRLIPAGTGGAT
QQVRHIAASRDNVVLEARREEAEAAAALAAPMADDAADADFLVETPESRD
>Mature_1410_residues
MNQEITNNPFNPLTPPKVFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRM
KYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLKSLPSRIGLMLDMTLRDLERVLYFENYVVIEPGLTDLQYGQ
MMTEEEYMDAQDAYGMDAFTANIGAEAIREMLAAIDLEAEAEHLRAELAEATGELKPKKIIKRLKVVESFLESGNRPEWM
IMTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRVIT
GANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVTGPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQA
KKLVEKERPEVWDILDEVIREHPVMLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYLTLEREGMKGEGKIFGNLDEVQHALDAGEVHLHSKVTVRVPQIDE
EGNEVFQRFETTPGRARLGSLLPKNAKAPFELVNRLLRKREVQQVIDTVYRYCGQKESVIFCDQIMTMGFREAFKAGISF
GKDDMVIPDNKWTIVDDTRDQVKDFEQQYMDGLITQGEKYNKVVDAWSKCNDKLTEAMMSTISAVKKAEDGSDMEPNSVY
MMAHSGARGSVTQMRQLGGMRGLMAKPNGDIIETPVISNFKEGLTVLEYFNSTHGARKGLSDTALKTANSGYLTRRLVDV
AQDCIVREHDCGTERAITAETAVNDGEVVASLGERILGRVAADDVKRPGTEEVLLAAGQLIDERMADTIEEAGVQSMRIR
SPLTCESEEGVCAMCYGRDLARGTMVNSGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFLEASQEGKIVFENTN
TLTNANGEVLTIGRNMKLIIQDEHGEERSSHKLGYGTKLFVKEGQEVKRGDKLFEWDPYTLPIIAEKPGTAKYVDLVSGL
AVREETDDATGMTQKIVIDWRAAPKGSDLKPEIILVGDDGEPVRNSLGNPLTYPMSVDAILSCEDGQKIEAGDVVARIPR
EGAKTKDITGGLPRVAELFEARRPKDHAIIAEIDGYVRFGRDYKNKRRISIEPADESMEAVEYMVPKGKHIPVVEGDFVQ
KGDYIMDGNPAPHDILSIMGVEALANYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWEISDSGETTLLKGEHVDKQEF
DAANEKALARGKRPAQGEPILLGITKASLQTRSFISAASFQETTRVLTEASVQGKKDKLVGLKENVIVGRLIPAGTGGAT
QQVRHIAASRDNVVLEARREEAEAAAALAAPMADDAADADFLVETPESRD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=938, Percent_Identity=25.9061833688699, Blast_Score=191, Evalue=5e-48,
Organism=Homo sapiens, GI39725938, Length=1031, Percent_Identity=24.5392822502425, Blast_Score=181, Evalue=4e-45,
Organism=Homo sapiens, GI103471997, Length=249, Percent_Identity=28.5140562248996, Blast_Score=91, Evalue=8e-18,
Organism=Escherichia coli, GI2367335, Length=1382, Percent_Identity=59.4066570188133, Blast_Score=1667, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=907, Percent_Identity=25.0275633958104, Blast_Score=170, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI25145495, Length=308, Percent_Identity=32.1428571428571, Blast_Score=143, Evalue=9e-34,
Organism=Saccharomyces cerevisiae, GI6324690, Length=565, Percent_Identity=26.3716814159292, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6320061, Length=549, Percent_Identity=27.1402550091075, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI17530899, Length=865, Percent_Identity=24.7398843930636, Blast_Score=171, Evalue=2e-42,
Organism=Drosophila melanogaster, GI281360912, Length=336, Percent_Identity=29.7619047619048, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17647875, Length=397, Percent_Identity=24.4332493702771, Blast_Score=101, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 156715; Mature: 156715

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQEITNNPFNPLTPPKVFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFC
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEE
ARIFGPIKDYECLCGKYKRMKYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLK
EHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHH
SLPSRIGLMLDMTLRDLERVLYFENYVVIEPGLTDLQYGQMMTEEEYMDAQDAYGMDAFT
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHCCHHHHCCCHHCCCCCHHH
ANIGAEAIREMLAAIDLEAEAEHLRAELAEATGELKPKKIIKRLKVVESFLESGNRPEWM
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEE
IMTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKR
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHH
MLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVT
HHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEE
GPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQAKKLVEKERPEVWDILDEVIR
CCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EHPVMLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
HCCEEECCCCCHHHHCHHHCCCEEECCCEEEEEHHHHHHCCCCCCCCCEEEEECCEECCC
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYLTLEREGMKGEGKIFGNLDEVQHAL
CCEEEEEEECCCCCCCCCCCEEEECCCHHHEEEEEEEEECCCCCCCCCEECCHHHHHHHH
DAGEVHLHSKVTVRVPQIDEEGNEVFQRFETTPGRARLGSLLPKNAKAPFELVNRLLRKR
CCCCEEEECEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
EVQQVIDTVYRYCGQKESVIFCDQIMTMGFREAFKAGISFGKDDMVIPDNKWTIVDDTRD
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCHH
QVKDFEQQYMDGLITQGEKYNKVVDAWSKCNDKLTEAMMSTISAVKKAEDGSDMEPNSVY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
MMAHSGARGSVTQMRQLGGMRGLMAKPNGDIIETPVISNFKEGLTVLEYFNSTHGARKGL
EEEECCCCCCHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCHHHHCCC
SDTALKTANSGYLTRRLVDVAQDCIVREHDCGTERAITAETAVNDGEVVASLGERILGRV
CHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHH
AADDVKRPGTEEVLLAAGQLIDERMADTIEEAGVQSMRIRSPLTCESEEGVCAMCYGRDL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCEEEEECCCHH
ARGTMVNSGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFLEASQEGKIVFENTN
HCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHCCCCCEEEECCC
TLTNANGEVLTIGRNMKLIIQDEHGEERSSHKLGYGTKLFVKEGQEVKRGDKLFEWDPYT
EEECCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHCCCCCEECCCEE
LPIIAEKPGTAKYVDLVSGLAVREETDDATGMTQKIVIDWRAAPKGSDLKPEIILVGDDG
EEEEECCCCCHHHHHHHHCCHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEECCCC
EPVRNSLGNPLTYPMSVDAILSCEDGQKIEAGDVVARIPREGAKTKDITGGLPRVAELFE
CHHHHHCCCCEECCEEECEEEECCCCCEECCCHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGYVRFGRDYKNKRRISIEPADESMEAVEYMVPKGKHIPVVEGDFVQ
HCCCCCCEEEEEECCHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCEECCCCCC
KGDYIMDGNPAPHDILSIMGVEALANYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWE
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCC
ISDSGETTLLKGEHVDKQEFDAANEKALARGKRPAQGEPILLGITKASLQTRSFISAASF
CCCCCCEEEEECCCCCHHHHCCCCHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
QETTRVLTEASVQGKKDKLVGLKENVIVGRLIPAGTGGATQQVRHIAASRDNVVLEARRE
HHHHHHHHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHH
EAEAAAALAAPMADDAADADFLVETPESRD
HHHHHHHHHCCCCCCCCCCCEEEECCCCCC
>Mature Secondary Structure
MNQEITNNPFNPLTPPKVFDEIKVSLASPERILSWSYGEIKKPETINYRTFKPERDGLFC
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEE
ARIFGPIKDYECLCGKYKRMKYRGVVCEKCGVEVTLQKVRRERMGHIELAAPVAHIWFLK
EHHHCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHH
SLPSRIGLMLDMTLRDLERVLYFENYVVIEPGLTDLQYGQMMTEEEYMDAQDAYGMDAFT
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHCCHHHHCCCHHCCCCCHHH
ANIGAEAIREMLAAIDLEAEAEHLRAELAEATGELKPKKIIKRLKVVESFLESGNRPEWM
HHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCEE
IMTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKR
EEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHH
MLQESVDALFDNGRRGRVITGANKRPLKSLSDMLKGKQGRFRQNLLGKRVDFSGRSVIVT
HHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCEEEEE
GPELKLHQCGLPKKMALELFKPFIYSRLEAKGLSSTVKQAKKLVEKERPEVWDILDEVIR
CCCEEEHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
EHPVMLNRAPTLHRLGIQAFEPTLIEGKAIQLHPLVCSAFNADFDGDQMAVHVPLSLEAQ
HCCEEECCCCCHHHHCHHHCCCEEECCCEEEEEHHHHHHCCCCCCCCCEEEEECCEECCC
LEARVLMMSTNNVLSPANGAPIIVPSQDMILGLYYLTLEREGMKGEGKIFGNLDEVQHAL
CCEEEEEEECCCCCCCCCCCEEEECCCHHHEEEEEEEEECCCCCCCCCEECCHHHHHHHH
DAGEVHLHSKVTVRVPQIDEEGNEVFQRFETTPGRARLGSLLPKNAKAPFELVNRLLRKR
CCCCEEEECEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHH
EVQQVIDTVYRYCGQKESVIFCDQIMTMGFREAFKAGISFGKDDMVIPDNKWTIVDDTRD
HHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEECCCHH
QVKDFEQQYMDGLITQGEKYNKVVDAWSKCNDKLTEAMMSTISAVKKAEDGSDMEPNSVY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
MMAHSGARGSVTQMRQLGGMRGLMAKPNGDIIETPVISNFKEGLTVLEYFNSTHGARKGL
EEEECCCCCCHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHCCHHHHCCC
SDTALKTANSGYLTRRLVDVAQDCIVREHDCGTERAITAETAVNDGEVVASLGERILGRV
CHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHCCCCHHHHHHHHHHHHHHH
AADDVKRPGTEEVLLAAGQLIDERMADTIEEAGVQSMRIRSPLTCESEEGVCAMCYGRDL
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCCCEEEEECCCHH
ARGTMVNSGEAVGIIAAQSIGEPGTQLTMRTFHIGGVAQGGQQSFLEASQEGKIVFENTN
HCCCCCCCCCEEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHCCCCCEEEECCC
TLTNANGEVLTIGRNMKLIIQDEHGEERSSHKLGYGTKLFVKEGQEVKRGDKLFEWDPYT
EEECCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCEEEEEECCCHHHCCCCCEECCCEE
LPIIAEKPGTAKYVDLVSGLAVREETDDATGMTQKIVIDWRAAPKGSDLKPEIILVGDDG
EEEEECCCCCHHHHHHHHCCHHCCCCCCCCCCEEEEEEEEECCCCCCCCCCCEEEECCCC
EPVRNSLGNPLTYPMSVDAILSCEDGQKIEAGDVVARIPREGAKTKDITGGLPRVAELFE
CHHHHHCCCCEECCEEECEEEECCCCCEECCCHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ARRPKDHAIIAEIDGYVRFGRDYKNKRRISIEPADESMEAVEYMVPKGKHIPVVEGDFVQ
HCCCCCCEEEEEECCHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCEECCCCCC
KGDYIMDGNPAPHDILSIMGVEALANYMIDEVQDVYRLQGVKINDKHIEVIVRQMLQKWE
CCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCC
ISDSGETTLLKGEHVDKQEFDAANEKALARGKRPAQGEPILLGITKASLQTRSFISAASF
CCCCCCEEEEECCCCCHHHHCCCCHHHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
QETTRVLTEASVQGKKDKLVGLKENVIVGRLIPAGTGGATQQVRHIAASRDNVVLEARRE
HHHHHHHHHHHCCCCCHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEHHH
EAEAAAALAAPMADDAADADFLVETPESRD
HHHHHHHHHCCCCCCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA