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The map label for this gene is 99079948

Identifier: 99079948

GI number: 99079948

Start: 113804

End: 114856

Strand: Reverse

Name: 99079948

Synonym: TM1040_0107

Alternate gene names: NA

Gene position: 114856-113804 (Counterclockwise)

Preceding gene: 99079949

Following gene: 99079947

Centisome position: 3.59

GC content: 63.25

Gene sequence:

>1053_bases
ATGACACATCTCTGGGTCCGGGCCGAACAGCGCCTGAACGAGGATCGCGTGGGGCTGACGCCTGCAGGGGCCAAGGCGCT
TCTGGAAGCGGGTATTCGCGTTACCGTCGAAGAAAGCAGCAGCCGCGCCATCCCGCTTCAGGGCTACATCGATGCAGGCT
GCGAAATTGCGCCAGAAAACGCCTGGCCCGATGCGCCGCGTGACGCCATCATCTTTGGCCTCAAGGAGCTGCCCGACGAC
GGCACCCCACTGCCCCATCGCCACATCATGTTTGGTCACGCTTTCAAAGGCCAGCACTCCGGCAAGGAACTGCTGCGCCG
GTTCCGCGAGGGCGGCGGGACGCTTTATGATCTGGAGTATCTGGTGGATCCGTCCGGCCGCAGGGTCGCCGCCTTTGGCT
ATTGGGCCGGGTATGCAGGTGCTGCTGTCACGCTCAAGGCCTGGGCCGCACAGCAGCGCGGCGAAACCTGCGGGCCGGTT
GGGGTCTACAAGAACAAGGACGCGCTTCTGGCCGATCTCGGCCGCGAGTTGGACGCCACCGGTGCAGACCGTCCCAAGGC
CATTGTCATCGGCGCTCTGGGTCGGGTGGGCACTGGCGCTGCGGATCTCTGCGAGGCGATGGGTGTTGCCGTCACCAAAT
GGGATATGAACGAGACCGCGAGCGGCGGACCGTTCCCGGAAATCCTCGACCATGATCTGTTCCTGAACTGCATCTTTGCC
CGCCCCGGTACGCCCGTTTTTGTGCCCAAAGAGGCGCTCACGGCCGCGCGCAACCTTACCGCAATCGGGGATGTAGCCTG
TGATCCGGACAGCGATTACAATCCCGTCCCCGTCTATTCCCGCGCAACCACATGGGATGCGCCGGTTGTACGTGTTGCCA
ATGATCCAGTCCTGGACGTAATGGCGATCGACAACCTCCCCTCGATGCTTCCTGCCGAAAGCTCCGAGGATTACGCGGAT
CAGCTTCTGGCAAGCCTTCTGACCCTGTCCGATCTGGATGCGGGCGTCTGGGGCCGGGCCAAGGCGGTCTTTGACGAACA
TGTGGCGGGCTGA

Upstream 100 bases:

>100_bases
TGGCAGGTTTTCCAAAACTCAGAGCCTTCATCGAGGCGATGGACGCGCGCGACAGCGTCAAGACTGTGCGCGCCAAAGAT
ATGCTTTAAGGAACAAGACT

Downstream 100 bases:

>100_bases
AAAGCCTGCCCAGATCAAGGAGAACAACTATGACTATTCACTGGTGCGGCACCGGCCTCTCCGCCATTCCCGGCCTGCGT
CGCCTGCTCGAAGCGGGTCA

Product: saccharopine dehydrogenase (NAD+, L-lysine-forming)

Products: L-lysine; 2-oxoglutarate; NADH; H+

Alternate protein names: NAD(P) Transhydrogenase Subunit Alpha; Alanine Dehydrogenase/PNT Domain-Containing Protein; Alanine Dehydrogenase/PNT Domain Protein; Oxidoreductase; Alanine Dehydrogenase/PNT N-Terminal Domain Family

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTHLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPENAWPDAPRDAIIFGLKELPDD
GTPLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLEYLVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQRGETCGPV
GVYKNKDALLADLGRELDATGADRPKAIVIGALGRVGTGAADLCEAMGVAVTKWDMNETASGGPFPEILDHDLFLNCIFA
RPGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPVVRVANDPVLDVMAIDNLPSMLPAESSEDYAD
QLLASLLTLSDLDAGVWGRAKAVFDEHVAG

Sequences:

>Translated_350_residues
MTHLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPENAWPDAPRDAIIFGLKELPDD
GTPLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLEYLVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQRGETCGPV
GVYKNKDALLADLGRELDATGADRPKAIVIGALGRVGTGAADLCEAMGVAVTKWDMNETASGGPFPEILDHDLFLNCIFA
RPGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPVVRVANDPVLDVMAIDNLPSMLPAESSEDYAD
QLLASLLTLSDLDAGVWGRAKAVFDEHVAG
>Mature_349_residues
THLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPENAWPDAPRDAIIFGLKELPDDG
TPLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLEYLVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQRGETCGPVG
VYKNKDALLADLGRELDATGADRPKAIVIGALGRVGTGAADLCEAMGVAVTKWDMNETASGGPFPEILDHDLFLNCIFAR
PGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPVVRVANDPVLDVMAIDNLPSMLPAESSEDYADQ
LLASLLTLSDLDAGVWGRAKAVFDEHVAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI17541738, Length=390, Percent_Identity=23.8461538461538, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322225, Length=360, Percent_Identity=43.0555555555556, Blast_Score=279, Evalue=4e-76,
Organism=Drosophila melanogaster, GI23397395, Length=400, Percent_Identity=24.25, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.7

Molecular weight: Translated: 37447; Mature: 37315

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPEN
CCEEEEEHHHHCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCEECCCCCCCCCCEECCCC
AWPDAPRDAIIFGLKELPDDGTPLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLEY
CCCCCCCHHEEEEHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEE
LVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQRGETCGPVGVYKNKDALLADLGRELDAT
EECCCCCEEEEEECHHHHCCCEEEHHHHHHHHCCCCCCCCCEECCCCHHHHHHCCHHCCC
GADRPKAIVIGALGRVGTGAADLCEAMGVAVTKWDMNETASGGPFPEILDHDLFLNCIFA
CCCCCCEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCHHHHCCCEEEEEEEE
RPGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPVVRVANDPVLDV
CCCCCEEECHHHHHHHHCCCEECCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
MAIDNLPSMLPAESSEDYADQLLASLLTLSDLDAGVWGRAKAVFDEHVAG
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
THLWVRAEQRLNEDRVGLTPAGAKALLEAGIRVTVEESSSRAIPLQGYIDAGCEIAPEN
CEEEEEHHHHCCCCCCCCCCCCHHHHHHCCCEEEEECCCCCEECCCCCCCCCCEECCCC
AWPDAPRDAIIFGLKELPDDGTPLPHRHIMFGHAFKGQHSGKELLRRFREGGGTLYDLEY
CCCCCCCHHEEEEHHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEE
LVDPSGRRVAAFGYWAGYAGAAVTLKAWAAQQRGETCGPVGVYKNKDALLADLGRELDAT
EECCCCCEEEEEECHHHHCCCEEEHHHHHHHHCCCCCCCCCEECCCCHHHHHHCCHHCCC
GADRPKAIVIGALGRVGTGAADLCEAMGVAVTKWDMNETASGGPFPEILDHDLFLNCIFA
CCCCCCEEEEECCCCCCCCHHHHHHHHCCEEEEECCCCCCCCCCCHHHHCCCEEEEEEEE
RPGTPVFVPKEALTAARNLTAIGDVACDPDSDYNPVPVYSRATTWDAPVVRVANDPVLDV
CCCCCEEECHHHHHHHHCCCEECCEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEE
MAIDNLPSMLPAESSEDYADQLLASLLTLSDLDAGVWGRAKAVFDEHVAG
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N6-(L-1,3-dicarboxypropyl)-L-lysine; NAD+; H2O

Specific reaction: N6-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O = L-lysine + 2-oxoglutarate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA